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  1. Article ; Online: Introduction to Thematic Reviews on Neurovascular Diseases.

    Brown, Robert D / Lanzino, Giuseppe / Kallmes, David F

    Mayo Clinic proceedings

    2020  Volume 95, Issue 7, Page(s) 1310–1312

    MeSH term(s) Cerebrovascular Disorders/therapy ; Humans ; Review Literature as Topic
    Language English
    Publishing date 2020-07-01
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2020.05.019
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  2. Article ; Online: Rabbit Elastase Aneurysm Model Mimics the Recurrence Rate of Human Intracranial Aneurysms following Platinum Coil Embolization.

    Ding, Y-H / Ghozy, S / Dai, D / Brinjikji, W / Kallmes, D F / Kadirvel, R

    AJNR. American journal of neuroradiology

    2022  Volume 43, Issue 5, Page(s) 741–747

    Abstract: Background and purpose: Intracranial aneurysms treated with coils have been associated with incomplete occlusion, particularly in large or wide-neck aneurysms. This study aimed to validate the accuracy of the rabbit elastase model in predicting aneurysm ...

    Abstract Background and purpose: Intracranial aneurysms treated with coils have been associated with incomplete occlusion, particularly in large or wide-neck aneurysms. This study aimed to validate the accuracy of the rabbit elastase model in predicting aneurysm recurrence in humans treated with platinum coils.
    Materials and methods: Elastase-induced saccular aneurysms were induced in rabbits and embolized with conventional platinum coils. The recurrence rates of aneurysms were retrospectively analyzed. Morphologic characteristics of aneurysms, angiographic outcomes, and histologic healing were evaluated.
    Results: A total of 28 (15.3%) of 183 aneurysms recurred. The aneurysm recurrence rate observed in this study (15.3%) is similar to those reported in multiple analyses of aneurysm recurrence rates in humans (7%-27%). The rate of recurrence was higher in aneurysms treated without balloon assistance (19/66, 28.8%) compared with those treated with balloon assistance (9/117, 7.7%). Aneurysms treated with balloon-assisted coiling had a lower recurrence rate (OR = 0.17; 95% CI, 0.05-0.47;
    Conclusions: The rabbit elastase aneurysm model may mimic aneurysm recurrence rates observed in humans after platinum coil embolization. Moreover, balloon assistance and high packing densities were significant predictors of aneurysm recurrence and occlusion.
    MeSH term(s) Animals ; Embolization, Therapeutic ; Humans ; Intracranial Aneurysm/chemically induced ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/therapy ; Pancreatic Elastase ; Platinum/adverse effects ; Rabbits ; Recurrence ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Platinum (49DFR088MY) ; Pancreatic Elastase (EC 3.4.21.36)
    Language English
    Publishing date 2022-04-28
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A7497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1580: Show issues Location:
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  3. Article ; Online: Comparison of citation rates between Covid-19 and non-Covid-19 articles across 24 major scientific journals.

    Brandt, Michael D / Ghozy, Sherief A / Kallmes, David F / McDonald, Robert J / Kadirvel, Ramanathan D

    PloS one

    2022  Volume 17, Issue 7, Page(s) e0271071

    Abstract: Covid-19 has been front and center in the global landscape since the beginning of 2020. In response, the scientific field has dedicated enormous amounts of resources to researching the virus and its effects. The number of times Covid-19 publications are ... ...

    Abstract Covid-19 has been front and center in the global landscape since the beginning of 2020. In response, the scientific field has dedicated enormous amounts of resources to researching the virus and its effects. The number of times Covid-19 publications are being cited throughout the literature appears remarkably high but has not been directly compared to non-Covid-19 papers in the same journals over an extended period. In our study, we use Clarivate's Web of Science-Science Citation Index Expanded™ database to identify Covid-19 papers published in 24 major scientific journals over a period of 24 months from January 1, 2020 to December 31, 2021. We conduct our search using keywords "Covid-19", "coronavirus", and "sars-cov-2" to locate publications with these words in the title. We then quantify the number of citations these papers have received and compare rates to non-Covid-19 papers in the same journals over the same timeframe. We find that, across 24 open-access and subscription-based scientific journals, Covid-19 papers published in the past 2 years currently have a median citation rate of 120.79 compared to 21.63 for non-Covid-19 papers. When negative binomial regression is used to minimize the influence of other variables such as article number variation and field of research, Covid-19 papers have still experienced more than 80% increase in citations relative to non-Covid-19 papers. These novel findings demonstrate that Covid-19 papers are being cited at remarkably higher rates than non-Covid-19 articles contained within the same journals. This suggests that journal impact factor, which is a product of the number of citations that recently published articles receive, will likely be drastically influenced by the number of Covid-19 papers that a journal has included within its pages in the previous years.
    MeSH term(s) COVID-19/epidemiology ; Databases, Factual ; Humans ; Journal Impact Factor ; Periodicals as Topic ; Publications
    Language English
    Publishing date 2022-07-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0271071
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  4. Article ; Online: Radiology-Pathology Correlations of Intracranial Clots: Current Theories, Clinical Applications, and Future Directions.

    Benson, J C / Kallmes, D F / Larson, A S / Brinjikji, W

    AJNR. American journal of neuroradiology

    2021  Volume 42, Issue 9, Page(s) 1558–1565

    Abstract: In recent years, there has been substantial progression in the field of stroke clot/thrombus imaging. Thrombus imaging aims to deduce the histologic composition of the clot through evaluation of various imaging characteristics. If the histology of a ... ...

    Abstract In recent years, there has been substantial progression in the field of stroke clot/thrombus imaging. Thrombus imaging aims to deduce the histologic composition of the clot through evaluation of various imaging characteristics. If the histology of a thrombus can be reliably determined by noninvasive imaging methods, critical information may be extrapolated about its expected response to treatment and about the patient's clinical outcome. Crucially, as we move into an era of stroke therapy individualization, determination of the histologic composition of a clot may be able to guide precise and targeted therapeutic effort. Most radiologists, however, remain largely unfamiliar with the topic of clot imaging. This article will review the current literature regarding clot imaging, including its histologic backdrop, the correlation of images with cellular components and treatment responsiveness, and future expectations.
    MeSH term(s) Humans ; Intracranial Thrombosis/diagnostic imaging ; Radiography ; Radiology ; Stroke/diagnostic imaging ; Thrombosis/diagnostic imaging
    Language English
    Publishing date 2021-07-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A7249
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  5. Article ; Online: TICI: if you are not confused, then you are not paying attention.

    Kallmes, D F

    AJNR. American journal of neuroradiology

    2012  Volume 33, Issue 5, Page(s) 975–976

    MeSH term(s) Brain Diseases/therapy ; Cerebral Revascularization/methods ; Humans ; Thrombolytic Therapy/methods
    Language English
    Publishing date 2012-01-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A2905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Point: CFD--computational fluid dynamics or confounding factor dissemination.

    Kallmes, D F

    AJNR. American journal of neuroradiology

    2012  Volume 33, Issue 3, Page(s) 395–396

    MeSH term(s) Computer Simulation ; Diagnosis, Computer-Assisted/methods ; Humans ; Image Interpretation, Computer-Assisted/methods ; Intracranial Aneurysm/diagnosis ; Intracranial Aneurysm/physiopathology ; Models, Cardiovascular ; Rheology/methods
    Language English
    Publishing date 2012-01-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A2993
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  7. Article ; Online: Evaluation of Outcome Prediction of Flow Diversion for Intracranial Aneurysms.

    Hadad, S / Mut, F / Kadirvel, R / Ding, Y-H / Kallmes, D / Cebral, J R

    AJNR. American journal of neuroradiology

    2021  Volume 42, Issue 11, Page(s) 1973–1978

    Abstract: Background and purpose: Identifying and predicting which aneurysms are likely to quickly occlude and which ones are likely to remain open following treatment with flow-diverting devices is important to develop optimal patient management strategies. The ... ...

    Abstract Background and purpose: Identifying and predicting which aneurysms are likely to quickly occlude and which ones are likely to remain open following treatment with flow-diverting devices is important to develop optimal patient management strategies. The purpose of this study was to evaluate predictions based on computational fluid dynamics models using the elastase rabbit aneurysm model.
    Materials and methods: A series of 13 aneurysms created in rabbits were treated with flow diverters, and outcomes were angiographically assessed at 8 weeks' follow-up. Computational fluid dynamics models were constructed from pretreatment 3D rotational angiograms and Doppler ultrasound flow velocity measurements. Postimplantation mean aneurysm inflow rate and flow velocity were used to prospectively predict aneurysm occlusion blinded to the actual outcomes. Specifically, if both variables were below their corresponding thresholds, fast occlusion was predicted, while if one of them was above the threshold, slow or incomplete occlusion was predicted.
    Results: Of the 13 aneurysms included, 8 were incompletely occluded 8 weeks after treatment, and 5 were completely occluded. A total of 10 computational fluid dynamics-based predictions agreed with the angiographic outcome, reaching 77% accuracy, 80% sensitivity, and 75% specificity. Posttreatment mean velocity alone was able to achieve the same predictive power as the combination of inflow rate and velocity.
    Conclusions: Subject-specific computational fluid dynamics models of the hemodynamic conditions created immediately after implantation of flow-diverting devices in experimental aneurysms created in rabbits are capable of prospectively predicting, with a reasonable accuracy, which aneurysms will completely occlude and which ones will remain incompletely occluded.
    MeSH term(s) Animals ; Hemodynamics ; Hydrodynamics ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Pancreatic Elastase ; Prognosis ; Rabbits ; Treatment Outcome
    Chemical Substances Pancreatic Elastase (EC 3.4.21.36)
    Language English
    Publishing date 2021-08-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A7263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Identifying "truth" in computational fluid dynamics research.

    Kallmes, D F

    AJNR. American journal of neuroradiology

    2011  Volume 32, Issue 6, Page(s) E122; author reply E123

    MeSH term(s) Cerebral Angiography/methods ; Cerebrovascular Circulation ; Female ; Humans ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/physiopathology ; Male ; Models, Cardiovascular ; Radiographic Image Interpretation, Computer-Assisted/methods ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2011-04-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A2537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Flow reversal in distal collaterals as a possible mechanism of delayed intraparenchymal hemorrhage after flow diversion treatment of cerebral aneurysms.

    Hadad, Sara / Pradhan, Aseem / Kadirvel, Ramanathan / Kallmes, David / Cebral, Juan R / Mut, Fernando

    Frontiers in physiology

    2022  Volume 13, Page(s) 881627

    Abstract: Background and Purpose: ...

    Abstract Background and Purpose:
    Language English
    Publishing date 2022-07-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.881627
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  10. Article ; Online: Treatment of giant intracranial aneurysms using the Pipeline flow-diverting stent: Long-term results from the International Retrospective Study of the Pipeline Embolization Device (IntrePED) study.

    Grandhi, Ramesh / Ravindra, Vijay M / Kallmes, David F / Lopes, Demetrius / Hanel, Ricardo A / Lylyk, Pedro

    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

    2022  , Page(s) 15910199221123282

    Abstract: Background: Traditional endovascular treatments of giant intracranial aneurysms are associated with high rates of complications and retreatment. Our objective was to examine the safety and long-term efficacy of the Pipeline Embolization Device for ... ...

    Abstract Background: Traditional endovascular treatments of giant intracranial aneurysms are associated with high rates of complications and retreatment. Our objective was to examine the safety and long-term efficacy of the Pipeline Embolization Device for treatment of these aneurysms.
    Methods: This retrospective study using the IntrePED database included all patients with giant intracranial aneurysms treated with the Pipeline device between July 2008 and February 2013. Efficacy outcomes were stratified by using the Raymond-Roy Occlusion Classification. Predefined safety outcomes included spontaneous rupture of the target aneurysm; ipsilateral intracranial hemorrhage; ischemic stroke; parent artery stenosis; and sustained cranial neuropathy.
    Results: Sixty-six embolizations were performed to treat 63 giant intracranial aneurysms (including 2 ruptured): 49 (77.8%) in the anterior and 14 (22.2%) in the posterior circulation. The median follow-up was 22.4 (0.1-60.5) months. Class I angiographic occlusion was achieved in 72.0% (36/50). The neurological morbidity/mortality rate was 23.8% (15/63), with higher rates in the posterior circulation than in the anterior circulation (22.4% vs. 28.6%). Among seven deaths, five had neurological causes. The procedure-related neurological morbidity and mortality rates were 22.7% (15/66) and 7.6% (5/66), respectively. The spontaneous rupture rate was 4.5% (3/66). Two spontaneous ruptures (1 death), 4/4 postprocedural intracranial hemorrhages, and 6/9 ischemic events occurred within 30 days. In-stent stenosis and new-onset cranial neuropathy were not observed during the angiographic follow-up period.
    Conclusions: Although procedure-related neurological morbidity/mortality rates were not insignificant, this study confirms the feasibility and long-term efficacy of the Pipeline Embolization Device to treat giant intracranial aneurysms.
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354913-3
    ISSN 2385-2011 ; 1591-0199 ; 1123-9344
    ISSN (online) 2385-2011
    ISSN 1591-0199 ; 1123-9344
    DOI 10.1177/15910199221123282
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