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  1. Article ; Online: Pressure ulcer risk assessment: Where will the journey take us?

    Kottner, Jan / Coleman, Susanne / Balzer, Katrin

    International journal of nursing studies

    2023  Volume 150, Page(s) 104646

    MeSH term(s) Humans ; Pressure Ulcer/prevention & control ; Risk Factors ; Risk Assessment ; Nursing Assessment
    Language English
    Publishing date 2023-11-22
    Publishing country England
    Document type Editorial
    ZDB-ID 80148-3
    ISSN 1873-491X ; 0020-7489
    ISSN (online) 1873-491X
    ISSN 0020-7489
    DOI 10.1016/j.ijnurstu.2023.104646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Epidemiologie von Salmonella enterica subspecies enterica serovar Bovismorbificans in Deutschland

    Balzer, Jan Christian

    klonale Analyse und epidemische Herkunft

    2002  

    Author's details vorgelegt von Jan Christian Balzer
    Language German
    Size 103 Bl. : Ill.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Essen, Univ., Diss., 2003
    HBZ-ID HT013648226
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Begründung pflegerischer Maßnahmen zur Hautreinigung und Hautpflege.

    Sill, Janna / Kottner, Jan / Balzer, Katrin

    Pflege

    2022  Volume 36, Issue 5, Page(s) 286–295

    Abstract: Justification of nurses' interventions for skin cleansing and skincare: Qualitative results of the SKINCARE-Pilot ... ...

    Title translation Justification of nurses' interventions for skin cleansing and skincare: Qualitative results of the SKINCARE-Pilot study.
    Abstract Justification of nurses' interventions for skin cleansing and skincare: Qualitative results of the SKINCARE-Pilot study
    MeSH term(s) Humans ; Nursing Homes ; Pilot Projects ; Long-Term Care ; Skin Care ; Nurses ; Qualitative Research
    Language German
    Publishing date 2022-05-04
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 645005-2
    ISSN 1664-283X ; 1012-5302
    ISSN (online) 1664-283X
    ISSN 1012-5302
    DOI 10.1024/1012-5302/a000882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Laser diode based THz-TDS system with 133 dB peak signal-to-noise ratio at 100 GHz.

    Cherniak, Vladyslav / Kubiczek, Tobias / Kolpatzeck, Kevin / Balzer, Jan C

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 13476

    Abstract: Terahertz time-domain spectroscopy (THz-TDS) has emerged as a powerful and versatile tool in various scientific fields. These include-among others-imaging, material characterization, and layer thickness measurements. While THz-TDS has achieved ... ...

    Abstract Terahertz time-domain spectroscopy (THz-TDS) has emerged as a powerful and versatile tool in various scientific fields. These include-among others-imaging, material characterization, and layer thickness measurements. While THz-TDS has achieved significant success in research environments, the high cost and bulky nature of most systems have hindered widespread commercialization of this technology. Two primary factors contributing to the size and cost of these systems are the laser and the optical delay unit (ODU). Consequently, our group has focused on developing THz-TDS systems based on compact monolithic mode-locked laser diodes (MLLDs). The ultra-high repetition rate (UHRR) of the MLLD has the added benefit that it allows us to utilize shorter ODUs, thereby reducing the overall cost and size of our systems. However, achieving the necessary precision in the ODU to acquire accurate terahertz time-domain signals remains a crucial aspect. To address this issue, we have developed and enhanced an interferometric extension for UHRR-THz-TDS systems. This extension is inexpensive, compact, and easy to incorporate. In this article, we present the system setup, the extension itself, and the algorithmic procedure for reconstructing the delay axis based on the interferometric reference signal. We evaluate a dataset comprising 10,000 signal traces and report a standard deviation of the measured terahertz phase at 1.6 THz as low as 3 mrad. Additionally, we demonstrate a remaining peak-to-peak jitter of only 20 fs and a record-high peak signal-to-noise ratio of 133 dB at 100 GHz after averaging. The method presented in this paper allows for simplified THz-TDS system builds, reducing bulk and cost. As a result, it further facilitates the transition of terahertz technologies from laboratory to field applications.
    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-40634-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comment on "International consensus on pressure injury preventative interventions by risk level for critically ill patients: A modified Delphi study".

    Kottner, Jan / Cuddigan, Janet / Balzer, Katrin / Haesler, Emily

    International wound journal

    2020  Volume 18, Issue 5, Page(s) 742–743

    MeSH term(s) Humans ; Consensus ; Critical Illness ; Delphi Technique ; Pressure Ulcer/prevention & control
    Language English
    Publishing date 2020-11-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2170920-8
    ISSN 1742-481X ; 1742-4801
    ISSN (online) 1742-481X
    ISSN 1742-4801
    DOI 10.1111/iwj.13520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Non-invasive glucose sensing via the fingernail bed using THz radiation

    Jalali Mandana / Prokscha Andreas / Yan Yijun / Kubiczek Tobias / Taro Svejda Jan / Preu Sascha / Balzer Jan / Kaiser Thomas / Erni Daniel

    Current Directions in Biomedical Engineering, Vol 9, Iss 1, Pp 507-

    2023  Volume 510

    Abstract: The possibility of establishing a novel technique for reliably accessing glycemic information in a non-invasive, easy to implement method at THz frequencies via the fingernail bed is investigated. The nail bed’s major content is blood at its various ... ...

    Abstract The possibility of establishing a novel technique for reliably accessing glycemic information in a non-invasive, easy to implement method at THz frequencies via the fingernail bed is investigated. The nail bed’s major content is blood at its various glucose levels and is also partially protected from environmental conditions by the nail plate, making it a desirable platform for non-invasive glucose sensing. The study is based on a 2D computational electromagnetics (EM) model of the layered fingernail in COMSOL Multiphysics, where the required dielectric function (i.e. permittivity and conductivity) of the fingernail plate is measured using THz-Time-Domain- Spectroscopy (THz-TDS), and the glucose-dependend dielectric functions of the fingernail bed are taken from available experimental data in the literature. From this data a material model using a multipole Cole-Cole model is established for both, the nail plate and the nail bed, where the glucose content in the latter is varied from 3.0-19.0 mmol/l. A numerical analysis of the THz reflectometry at the fingernail in the frequency range of 0.1-2.0 THz revealed that the reflectance spectra are sensitive to the glucose content in the nail bed proving that accurate glucose sensing via the fingernail bed may become feasible around 0.2-0.4 THz.
    Keywords diabetes ; glucose sensing ; fingernail bed ; cole- cole model ; thz radiation ; thz-tds ; Medicine ; R
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Repetition frequency tunability and stability of BH InAs/InP QD and InGaAsP/InP QW two-section mode-locked laser diodes.

    Cherniak, Vladyslav / Zander, Marlene / Moehrle, Martin / Rehbein, Wolfgang / Balzer, Jan C

    Optics express

    2022  Volume 30, Issue 19, Page(s) 34411–34419

    Abstract: Ultra-high repetition rate (UHRR) mode-locked laser diodes (MLLD) have shown promising results for applications based on optical sampling such as asynchronous optical sampling (ASOPS), optical sampling by repetition-rate tuning (OSBERT), and optical ... ...

    Abstract Ultra-high repetition rate (UHRR) mode-locked laser diodes (MLLD) have shown promising results for applications based on optical sampling such as asynchronous optical sampling (ASOPS), optical sampling by repetition-rate tuning (OSBERT), and optical ranging. Important metrics to consider are the repetition frequency (RF) and the RF linewidth. Here, we compare two monolithically integrated MLLDs. A quantum dot (QD) MLLD with an RF of approx. 50.1 GHz and a quantum well (QW) MLLD with an RF of approx. 51.4 GHz. The tunability of the RF is characterized by sweeping the lasers pump current, temperature, and saturable absorber (SA) reverse voltage. The QW MLLD has a tuning range of 31 MHz with an average RF linewidth of 53 kHz, while the QD MLLD has a smaller tuning range of 26 MHz with a higher average RF linewidth of 172 kHz.
    Language English
    Publishing date 2022-10-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.468031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Prevalence and associations of xerosis cutis, incontinence-associated dermatitis, skin tears, pressure ulcers, and intertrigo in aged nursing home residents: A representative prevalence study.

    Völzer, Bettina / El Genedy-Kalyoncu, Monira / Fastner, Alexandra / Tomova-Simitchieva, Tsenka / Neumann, Konrad / Sill, Janna / Balzer, Katrin / Kottner, Jan

    International journal of nursing studies

    2023  Volume 141, Page(s) 104472

    Abstract: Background: The number of elderly and care-dependent people is increasing, leading to increased risks of adverse skin conditions. Skin care, including prevention and treatment of vulnerable skin, is an essential part of daily nursing practice in long- ... ...

    Abstract Background: The number of elderly and care-dependent people is increasing, leading to increased risks of adverse skin conditions. Skin care, including prevention and treatment of vulnerable skin, is an essential part of daily nursing practice in long-term residential settings. For many years, the research focus has been on individual skin problems including xerosis cutis, incontinence-associated dermatitis, skin tears, pressure ulcers, and intertrigo, although people may be affected by several at the same time.
    Objectives: Aim of the present study was to describe the prevalence and associations of skin conditions relevant to nursing practice in aged nursing home residents.
    Design: Analysis of baseline data of a cluster-RCT in long-term residential settings.
    Setting: The study was conducted in a representative sample of n = 17 nursing homes in the federal state of Berlin, Germany.
    Participants: Care dependent nursing home residents being 65+ years.
    Methods: A random sample of all eligible nursing homes was drawn. Demographic and health characteristics were collected and head-to-toe skin examinations conducted by dermatologists. Prevalence estimates and intracluster correlation coefficients were calculated, and group comparisons conducted.
    Results: Three hundred fourteen residents with a mean age of 85.4 (SD 7.1) years were included. The majority was affected by xerosis cutis (95.9%, 95% CI 93.6 to 97.8), followed by intertrigo 35.0% (95% CI 30.0 to 40.1), incontinence-associated dermatitis 21.0% (95% CI 15.6 to 26.3), skin tears 10.5% (95% CI 7.3 to 13.8), and pressure ulcers 8.0% (95% CI 5.1 to 10.8). In total, more than half of the nursing home residents were affected by two or more skin conditions at the same time. Several associations between skin conditions and mobility, care dependency, or cognitive impairment were observed. There were no associations between xerosis cutis, incontinence-associated dermatitis, skin tears, pressure ulcers or intertrigo.
    Conclusions: The adverse skin and tissue conditions xerosis cutis, incontinence-associated dermatitis, skin tears, pressure ulcers and intertrigo are very common in long-term residential settings, placing a high burden on this population. Although care receivers share similar risk factors and may be affected by several skin conditions at the same time, there are no associations indicating separate aetiological pathways.
    Registration: This study is registered at the German Clinical Trials Register (registration number: DRKS00015680; date of registration: January 29th, 2019) and ClinicalTrials.gov (NCT03824886; date of registration: January 31st, 2019).
    MeSH term(s) Aged ; Humans ; Aged, 80 and over ; Pressure Ulcer/epidemiology ; Cross-Sectional Studies ; Prevalence ; Nursing Homes ; Skin Diseases ; Intertrigo
    Language English
    Publishing date 2023-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 80148-3
    ISSN 1873-491X ; 0020-7489
    ISSN (online) 1873-491X
    ISSN 0020-7489
    DOI 10.1016/j.ijnurstu.2023.104472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Haptoglobin depletion during the first seven days of veno-venous ECMO therapy is associated with increased mortality and adverse outcomes in patients with ARDS.

    Bünger, Victoria / Hunsicker, Oliver / Krannich, Alexander / Balzer, Felix / Spies, Claudia D / Kuebler, Wolfgang M / Weber-Carstens, Steffen / Menk, Mario / Graw, Jan A

    Shock (Augusta, Ga.)

    2024  

    Abstract: Background: Hemolysis is a frequent complication in patients with sepsis, ARDS, or extracorporeal membrane oxygenation (ECMO). Haptoglobin (Hp) can scavenge released cell-free hemoglobin (CFH). Hemolysis and low plasma concentrations of Hp may be ... ...

    Abstract Background: Hemolysis is a frequent complication in patients with sepsis, ARDS, or extracorporeal membrane oxygenation (ECMO). Haptoglobin (Hp) can scavenge released cell-free hemoglobin (CFH). Hemolysis and low plasma concentrations of Hp may be independently associated with mortality in critically ill patients.
    Methods: Retrospective analysis of 435 patients with ARDS and veno-venous ECMO therapy, admitted to a tertiary ARDS referral center (01/2007-12/2018). Hp-depletion was defined as decrease in plasma Hp concentration < 0.39 g/l within the first week after ECMO initiation. Patients with Hp depletion were compared to patients without Hp depletion. The primary endpoint was 28-day mortality. Secondary endpoints included organ dysfunction-free, renal replacement therapy (RRT)-free, vasopressor-free, and ECMO-free composites.
    Results: Patients with Hp-depletion (n = 269) had a significantly higher mortality 28 days after ECMO initiation compared to patients without Hp-depletion (43.5%, [95% CI: 37.52-49.66] vs. 25.3%, [19.03-32.74], p < 0.001). Furthermore, patients with Hp depletion had fewer organ dysfunction-free days (subdistribution hazard ratio, [SHR] 0.35, [95% CI 0.25-0.50], p < 0.001), lower chances for successful weaning from renal replacement therapy (SHR 0.50, [0.32-0.79], p < 0.001), vasopressor therapy (SHR 0.39, [0.28-0.54], p < 0.001), and ECMO therapy (SHR 0.41, [0.30-0.57], p < 0.001) within 28 days after ECMO initiation. Patients with initial Hp <0.66 g/l had higher risks for Hp-depletion than patients with initial Hp ≥ 0.66 g/l.
    Conclusion: Patients with Hp-depletion within the first week of ECMO therapy might benefit from close monitoring of hemolysis with early detection and elimination of the underlying cause. They might be potential candidates for future Hp supplementation therapy to prevent overload of the CFH-scavenger system.
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1185432-7
    ISSN 1540-0514 ; 1073-2322
    ISSN (online) 1540-0514
    ISSN 1073-2322
    DOI 10.1097/SHK.0000000000002352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Validity and reliability of an electromyography-based upper limb assessment quantifying selective voluntary motor control in children with upper motor neuron lesions.

    Keller, Jeffrey W / Fahr, Annina / Balzer, Julia / Lieber, Jan / van Hedel, Hubertus Ja

    Science progress

    2021  Volume 104, Issue 2, Page(s) 368504211008058

    Abstract: Current clinical assessments evaluating selective voluntary motor control are measured on an ordinal scale. We combined the Selective Control of the Upper Extremity Scale (SCUES) with surface electromyography to develop a more objective and interval- ... ...

    Abstract Current clinical assessments evaluating selective voluntary motor control are measured on an ordinal scale. We combined the Selective Control of the Upper Extremity Scale (SCUES) with surface electromyography to develop a more objective and interval-scaled assessment of selective voluntary motor control. The resulting Similarity Index (SI) quantifies the similarity of muscle activation patterns. We aimed to evaluate the validity and reliability of this new assessment named SI
    MeSH term(s) Adult ; Child ; Electromyography ; Humans ; Motor Neuron Disease/diagnosis ; Motor Neurons ; Reproducibility of Results ; Upper Extremity
    Language English
    Publishing date 2021-04-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504211008058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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