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  1. Article ; Online: Letter from the new commissioning editor-Martin Harper.

    Harper, Martin

    Journal of occupational and environmental hygiene

    2021  Volume 18, Issue 1, Page(s) D1

    MeSH term(s) Environmental Health ; Occupational Health ; Open Access Publishing ; Periodicals as Topic
    Language English
    Publishing date 2021-01-15
    Publishing country England
    Document type Editorial ; Letter
    ZDB-ID 2131820-7
    ISSN 1545-9632 ; 1545-9624
    ISSN (online) 1545-9632
    ISSN 1545-9624
    DOI 10.1080/15459624.2020.1859293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5821: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Research profile. Martin Harper.

    Harper, Martin

    Journal of environmental monitoring : JEM

    2004  Volume 6, Issue 10, Page(s) 124N–127N

    MeSH term(s) Education ; History, 20th Century ; History, 21st Century ; National Institute for Occupational Safety and Health (U.S.) ; Occupational Health/history ; Occupations ; Research ; United States
    Language English
    Publishing date 2004-10
    Publishing country England
    Document type Autobiography ; Biography ; Historical Article ; Journal Article
    ZDB-ID 1453583-x
    ISSN 1464-0333 ; 1464-0325
    ISSN (online) 1464-0333
    ISSN 1464-0325
    DOI 10.1039/b413406k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7401: Show issues

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  3. Article ; Online: The importance of assessing wall deposits in samplers for airborne particulates.

    White, Kenneth T / Ashley, Kevin / Harper, Martin

    Journal of occupational and environmental hygiene

    2024  , Page(s) 1–4

    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2131820-7
    ISSN 1545-9632 ; 1545-9624
    ISSN (online) 1545-9632
    ISSN 1545-9624
    DOI 10.1080/15459624.2024.2337692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5821: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Recent Advances in Occupational Exposure Assessment of Aerosols.

    Harper, Martin

    International journal of environmental research and public health

    2020  Volume 17, Issue 18

    Abstract: Exposure science is underpinned by characterization (measurement) of exposures. In this article, six recent advances in exposure characterization by sampling and analysis are reviewed as tools in the occupational exposure assessment of aerosols. Three ... ...

    Abstract Exposure science is underpinned by characterization (measurement) of exposures. In this article, six recent advances in exposure characterization by sampling and analysis are reviewed as tools in the occupational exposure assessment of aerosols. Three advances discussed in detail are (1) recognition and inclusion of sampler wall deposits; (2) development of a new sampling and analytical procedure for respirable crystalline silica that allows non-destructive field analysis at the end of the sampling period; and (3) development of a new sampler to collect the portion of sub-300 nm aerodynamic diameter particles that would deposit in human airways. Three additional developments are described briefly: (4) a size-selective aerosol sampler that allows the collection of multiple physiologically-relevant size fractions; (5) a miniaturized pump and versatile sampling head to meet multiple size-selective sampling criteria; and (6) a novel method of sampling bioaerosols including viruses while maintaining viability. These recent developments are placed in the context of the historical evolution in sampling and analytical developments from 1900 to the present day. While these are not the only advances in exposure characterization, or exposure assessment techniques, they provide an illustration of how technological advances are adding more tools to our toolkit. The review concludes with a number of recommended areas for future research, including expansion of real-time and end-of-shift on-site measurement, development of samplers that operate at higher flow-rates to ensure measurement at lowered limit values, and development of procedures that accurately distinguish aerosol and vapor phases of semi-volatile substances.
    MeSH term(s) Aerosols/analysis ; Aerosols/toxicity ; Air Pollutants, Occupational/analysis ; Dust/analysis ; Environmental Monitoring ; Humans ; Occupational Exposure/analysis ; Particle Size
    Chemical Substances Aerosols ; Air Pollutants, Occupational ; Dust
    Keywords covid19
    Language English
    Publishing date 2020-09-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17186820
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  5. Article ; Online: Recent Advances in Occupational Exposure Assessment of Aerosols

    Martin Harper

    International Journal of Environmental Research and Public Health, Vol 17, Iss 6820, p

    2020  Volume 6820

    Abstract: Exposure science is underpinned by characterization (measurement) of exposures. In this article, six recent advances in exposure characterization by sampling and analysis are reviewed as tools in the occupational exposure assessment of aerosols. Three ... ...

    Abstract Exposure science is underpinned by characterization (measurement) of exposures. In this article, six recent advances in exposure characterization by sampling and analysis are reviewed as tools in the occupational exposure assessment of aerosols. Three advances discussed in detail are (1) recognition and inclusion of sampler wall deposits; (2) development of a new sampling and analytical procedure for respirable crystalline silica that allows non-destructive field analysis at the end of the sampling period; and (3) development of a new sampler to collect the portion of sub-300 nm aerodynamic diameter particles that would deposit in human airways. Three additional developments are described briefly: (4) a size-selective aerosol sampler that allows the collection of multiple physiologically-relevant size fractions; (5) a miniaturized pump and versatile sampling head to meet multiple size-selective sampling criteria; and (6) a novel method of sampling bioaerosols including viruses while maintaining viability. These recent developments are placed in the context of the historical evolution in sampling and analytical developments from 1900 to the present day. While these are not the only advances in exposure characterization, or exposure assessment techniques, they provide an illustration of how technological advances are adding more tools to our toolkit. The review concludes with a number of recommended areas for future research, including expansion of real-time and end-of-shift on-site measurement, development of samplers that operate at higher flow-rates to ensure measurement at lowered limit values, and development of procedures that accurately distinguish aerosol and vapor phases of semi-volatile substances.
    Keywords exposure assessment ; aerosols ; air sampling ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Tourism Translation

    Patrizia Giampieri / Martin Harper

    Umanistica Digitale, Iss 14, Pp 119-

    from Corpus to Machine Translation (and back)

    2023  Volume 135

    Abstract: Tourism language is characterised by features which make it distinct from other sector-based or technical languages. There are many examples of corpus-based studies and corpus-driven translation in the tourism sector but little regarding machine ... ...

    Abstract Tourism language is characterised by features which make it distinct from other sector-based or technical languages. There are many examples of corpus-based studies and corpus-driven translation in the tourism sector but little regarding machine translation. Fewer still are the case studies or research papers dedicated to a comparison between machine-translated and corpus-based translated tourism texts. This paper aims to fill this gap by investigating whether, and to what extent, Google machine translation (from Italian into English) of a variety of tourism texts can be considered reliable or, at least, acceptable. To this end, it compares machine translations of tourism texts to their respective corpus-based translations. The paper’s findings uncover issues which mostly concern lexical and collocational choices, as well as a neglect of certain English writing conventions, such as those relating to clause structures, ego-targeting and figurative language. MT appears to perform well with informative and descriptive tourism texts, where sentences are simpler and no vivid language is involved. These, however, could hardly be considered representative of tourism texts, as a whole. The paper calls for advancements in MT algorithms in order to address certain lexical and collocational issues. Moreover, it is the opinion of the authors that MT in the tourism field is best left to translators capable of discerning accurate word usage in context.
    Keywords machine translation ; corpus-based translation ; tourism texts ; tourism translation ; tourism language ; General Works ; A ; History of scholarship and learning. The humanities ; AZ20-999
    Subject code 410
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher University of Bologna
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: To Everything, there is a season.

    Koyle, Martin / North, Amanda / Harper, Luke / Pinto, Kirk

    Journal of pediatric urology

    2022  Volume 18, Issue 5, Page(s) 552–553

    Language English
    Publishing date 2022-08-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2022.08.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6387: Show issues Location:
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  8. Article ; Online: Thermal Stability of Protic Ionic Liquids.

    Paporakis, Stefan / Liu, Kenny T-C / Brown, Stuart J / Harper, Jason B / Martin, Andrew V / Greaves, Tamar L

    The journal of physical chemistry. B

    2024  Volume 128, Issue 17, Page(s) 4208–4219

    Abstract: While protic ionic liquids (ILs) have found great success as solvents for a broad range of applications, little is known about their degradation when exposed to temperatures above ambient for extended periods of time. Here, we report the thermal ... ...

    Abstract While protic ionic liquids (ILs) have found great success as solvents for a broad range of applications, little is known about their degradation when exposed to temperatures above ambient for extended periods of time. Here, we report the thermal stability of six protic ILs, namely, ethylammonium nitrate, ethylammonium formate, ethylammonium acetate, ethanolammonium nitrate, ethanolammonium formate, and ethanolammonium acetate. The effect of heating each ionic liquid to 60 °C for 1 h or 1 week (sealed or open to the atmosphere) was evaluated by considering the changes to water content, pH, mass, thermal phase transitions, and molecular structure after each treatment. Heating each of the six ILs when sealed led to measurable shifts in their water content and 10 wt % pH, but there was no significant change in their mass, thermal phase transitions according to differential scanning calorimetry (DSC), or molecular structure using proton nuclear magnetic resonance (
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c08011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration.

    Martin, Shenée C / Joyce, Kathryn K / Harper, Kathryn M / Harp, Samuel J / Cohen, Todd J / Moy, Sheryl S / Diering, Graham H

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 3

    Abstract: Sleep disruption is an expected component of aging and neurodegenerative conditions, including Alzheimer's disease (AD). Sleep disruption has been demonstrated as a driver of AD pathology and cognitive decline. Therefore, treatments designed to maintain ... ...

    Abstract Sleep disruption is an expected component of aging and neurodegenerative conditions, including Alzheimer's disease (AD). Sleep disruption has been demonstrated as a driver of AD pathology and cognitive decline. Therefore, treatments designed to maintain sleep may be effective in slowing or halting AD progression. However, commonly used sleep aid medications are associated with an increased risk of AD, highlighting the need for sleep aids with novel mechanisms of action. The endocannabinoid system holds promise as a potentially effective and novel sleep-enhancing target. By using pharmacology and genetic knockout strategies, we evaluated fatty acid amide hydrolase (FAAH) as a therapeutic target to improve sleep and halt disease progression in a transgenic Tau P301S (PS19) model of Tauopathy and AD. We have recently shown that PS19 mice exhibit sleep disruption in the form of dark phase hyperarousal as an early symptom that precedes robust Tau pathology and cognitive decline. Acute FAAH inhibition with PF3845 resulted in immediate improvements in sleep behaviors in male and female PS19 mice, supporting FAAH as a potentially suitable sleep-promoting target. Moreover, sustained drug dosing for 5-10 days resulted in maintained improvements in sleep. To evaluate the effect of chronic FAAH inhibition as a possible therapeutic strategy, we generated FAAH-/- PS19 mice models. Counter to our expectations, FAAH knockout did not protect PS19 mice from progressive sleep loss, neuroinflammation, or cognitive decline. Our results provide support for FAAH as a novel target for sleep-promoting therapies but further indicate that the complete loss of FAAH activity may be detrimental.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17030319
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  10. Article: Liver regeneration biology: Implications for liver tumour therapies.

    Hadjittofi, Christopher / Feretis, Michael / Martin, Jack / Harper, Simon / Huguet, Emmanuel

    World journal of clinical oncology

    2022  Volume 12, Issue 12, Page(s) 1101–1156

    Abstract: The liver has remarkable regenerative potential, with the capacity to regenerate after 75% hepatectomy in humans and up to 90% hepatectomy in some rodent models, enabling it to meet the challenge of diverse injury types, including physical trauma, ... ...

    Abstract The liver has remarkable regenerative potential, with the capacity to regenerate after 75% hepatectomy in humans and up to 90% hepatectomy in some rodent models, enabling it to meet the challenge of diverse injury types, including physical trauma, infection, inflammatory processes, direct toxicity, and immunological insults. Current understanding of liver regeneration is based largely on animal research, historically in large animals, and more recently in rodents and zebrafish, which provide powerful genetic manipulation experimental tools. Whilst immensely valuable, these models have limitations in extrapolation to the human situation. In vitro models have evolved from 2-dimensional culture to complex 3 dimensional organoids, but also have shortcomings in replicating the complex hepatic micro-anatomical and physiological milieu. The process of liver regeneration is only partially understood and characterized by layers of complexity. Liver regeneration is triggered and controlled by a multitude of mitogens acting in autocrine, paracrine, and endocrine ways, with much redundancy and cross-talk between biochemical pathways. The regenerative response is variable, involving both hypertrophy and true proliferative hyperplasia, which is itself variable, including both cellular phenotypic fidelity and cellular trans-differentiation, according to the type of injury. Complex interactions occur between parenchymal and non-parenchymal cells, and regeneration is affected by the status of the liver parenchyma, with differences between healthy and diseased liver. Finally, the process of termination of liver regeneration is even less well understood than its triggers. The complexity of liver regeneration biology combined with limited understanding has restricted specific clinical interventions to enhance liver regeneration. Moreover, manipulating the fundamental biochemical pathways involved would require cautious assessment, for fear of unintended consequences. Nevertheless, current knowledge provides guiding principles for strategies to optimise liver regeneration potential.
    Language English
    Publishing date 2022-01-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2587357-X
    ISSN 2218-4333
    ISSN 2218-4333
    DOI 10.5306/wjco.v12.i12.1101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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