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  1. Book ; Online: Antarctica

    Kanao, Masaki / Toyokuni, Genti / Yamamoto, Masa-yuki

    A Key To Global Change

    2019  

    Keywords Environmental science, engineering & technology ; climate change, remote sensing, climate, isolation, transport, lakes
    Language English
    Size 1 electronic resource (136 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030647761
    ISBN 9781839621093 ; 1839621095
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Heterogeneity in a meta-analysis: randomized controlled trials versus observational studies.

    Kotani, Yuki / Yamamoto, Taihei / Shibata, Taisuke / Hayashi, Yoshiro

    Intensive care medicine

    2024  Volume 50, Issue 3, Page(s) 480–482

    MeSH term(s) Humans ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07337-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Photoinduced Synthesis of Bisphosphinated Quinoxalines via Radical Cyclization of o-Diisocyanoarenes with Diphosphines.

    Yamamoto, Yuki / Ogawa, Akiya

    Chemistry, an Asian journal

    2023  Volume 18, Issue 8, Page(s) e202201269

    Abstract: The cycloaddition reaction of o-diisocyanoarenes with interelement compounds under light is a very important reaction system to clarify whether this reaction proceeds by radical cyclization or by aza-Bergman cyclization. In this study, a series of ... ...

    Abstract The cycloaddition reaction of o-diisocyanoarenes with interelement compounds under light is a very important reaction system to clarify whether this reaction proceeds by radical cyclization or by aza-Bergman cyclization. In this study, a series of diphosphines with phosphorus-phosphorus single bonds were selected as interelement compounds, and their cycloaddition reactions with o-diisocyanoarenes under light were investigated in detail to achieve a novel photoinduced synthesis of bisphosphinated quinoxalines via the radical cyclization pathway. In addition, the photoinduced reaction of diphosphines with isocyanides having o-functional groups such as cyano and ethenyl groups allowed us to elucidate the reaction pathway and product selectivity of this bisphosphination. Furthermore, the one-pot synthesis of Pd
    Language English
    Publishing date 2023-02-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202201269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Metal-Free One-Pot Multi-Functionalization of Unsaturated Compounds with Interelement Compounds by Radical Process.

    Yamamoto, Yuki / Ogawa, Akiya

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 2

    Abstract: In recent years, the importance of "environmentally friendly manufacturing" has been increasing toward the establishment of a resource-recycling society. In organic synthesis, as well, it is becoming increasingly important to develop new synthetic ... ...

    Abstract In recent years, the importance of "environmentally friendly manufacturing" has been increasing toward the establishment of a resource-recycling society. In organic synthesis, as well, it is becoming increasingly important to develop new synthetic strategies with resource conservation and the recycling of elemental resources in mind, rather than just only synthesis. Many studies on the construction of frameworks of functional molecules using ionic reactions and transition-metal-catalyzed reactions have been reported, but most of them have focused on the formation of carbon-carbon bonds. However, it is essential to introduce appropriate functional groups at appropriate positions in molecules in order for the molecules to express their functions, and furthermore, the highly selective preparation of multiple functional groups is considered important for the creation of new functional molecules. In this review, we focus on radical reactions with high functional group selectivity and overview the recent progress in practical methods for the simultaneous introduction of multiple functional groups and propose future synthetic strategies that emphasize the recycling of elemental resources and environmental friendliness.
    MeSH term(s) Transition Elements/chemistry ; Metals ; Carbon/chemistry ; Chemistry Techniques, Synthetic
    Chemical Substances Transition Elements ; Metals ; Carbon (7440-44-0)
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28020787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Transition-Metal-Catalyzed Addition of Organosulfur Compounds to Alkynes and Alkenes: Catalysis and Catalyst Poisons.

    Yamamoto, Yuki / Ogawa, Akiya

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2023  Volume 29, Issue 64, Page(s) e202302432

    Abstract: The addition of heteroatom compounds to alkynes and alkenes is an atom-efficient method of carbon-heteroatom bond formation and is widely used as a fundamental synthetic method for the construction of functional molecules. Nevertheless, examples of ... ...

    Abstract The addition of heteroatom compounds to alkynes and alkenes is an atom-efficient method of carbon-heteroatom bond formation and is widely used as a fundamental synthetic method for the construction of functional molecules. Nevertheless, examples of transition-metal-catalyzed addition reactions of group 16 heteroatom compounds to carbon-carbon unsaturated bonds have been limited due to the widespread belief that organic sulfur and selenium compounds are representative catalyst poisons. In recent decades, however, several seminal catalytic reactions of sulfur compounds have been developed, providing important insights into catalysis and poisons. Therefore, this paper focuses on the transition-metal-catalyzed addition of organosulfur compounds to alkynes and alkenes, gains comprehensive insights into the catalysis and catalyst poisons, and proposes concepts for the development of transition-metal-catalyzed reactions of group 16 heteroatom compounds.
    Language English
    Publishing date 2023-10-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202302432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Multicomponent Reactions between Heteroatom Compounds and Unsaturated Compounds in Radical Reactions.

    Ogawa, Akiya / Yamamoto, Yuki

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 17

    Abstract: In this mini-review, we present our concepts for designing multicomponent reactions with reference to a series of sequential radical reactions that we have developed. Radical reactions are well suited for the design of multicomponent reactions due to ... ...

    Abstract In this mini-review, we present our concepts for designing multicomponent reactions with reference to a series of sequential radical reactions that we have developed. Radical reactions are well suited for the design of multicomponent reactions due to their high functional group tolerance and low solvent sensitivity. We have focused on the photolysis of interelement compounds with a heteroatom-heteroatom single bond, which readily generates heteroatom-centered radicals, and have studied the photoinduced radical addition of interelement compounds to unsaturated compounds. First, the background of multicomponent radical reactions is described, and basic concepts and methodology for the construction of multicomponent reactions are explained. Next, examples of multicomponent reactions involving two interelement compounds and one unsaturated compound are presented, as well as examples of multicomponent reactions involving one interelement compound and two unsaturated compounds. Furthermore, multicomponent reactions involving intramolecular cyclization processes are described.
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28176356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Practical synthesis of 1,3-benzoazaphosphole analogues.

    Yamamoto, Yuki / Mita, Soichiro / Sato, Yuki / Yano, Kentaro / Ogawa, Akiya

    Frontiers in chemistry

    2023  Volume 11, Page(s) 1174895

    Abstract: Despite the promising pharmacological activity and material properties of five-membered heterocyclic compounds containing phosphorus and nitrogen, synthetic examples of them have been rather limited due to the instability of phosphorus toward air and ... ...

    Abstract Despite the promising pharmacological activity and material properties of five-membered heterocyclic compounds containing phosphorus and nitrogen, synthetic examples of them have been rather limited due to the instability of phosphorus toward air and water. In this study, 1,3-benzoazaphosphol analogues were selected as target molecules, and various synthetic routes were examined to establish a fundamental technology for the introduction of phosphorus groups into aromatic rings and formation of five-membered rings containing phosphorus and nitrogen by cyclization. As a result, we found that 2-aminophenyl(phenyl)phosphine is an extremely promising synthetic intermediate with high stability and easy handling. Furthermore, 2-methyl-3-phenyl-2,3-dihydro-1
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2023.1174895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Manganese-Catalyzed 5-

    Yamamoto, Daisuke / Matsukawa, Daisuke / Kikuchi, Ryusei / Narushima, Yuki / Kumakura, Yuta / Ito, Mana / Makino, Kazuishi

    The Journal of organic chemistry

    2024  

    Abstract: The stereoselective 5- ...

    Abstract The stereoselective 5-
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.4c00390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Mycosis fungoides with pseudocarcinomatous hyperplasia masquerading as verrucous carcinoma.

    Saeki, Yuka / Miyachi, Hideaki / Miura, Keiko / Okazaki, Daijiro / Yamamoto, Makoto / Yuki, Yumika / Nakano, Michiyo

    JAAD case reports

    2023  Volume 39, Page(s) 130–134

    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.07.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparing interplay effects in scanned proton therapy of lung cancer: Free breathing with various layer and volume rescanning versus respiratory gating with different gate widths.

    Tominaga, Yuki / Suga, Masaki / Takeda, Mikuni / Yamamoto, Yuki / Akagi, Takashi / Kato, Takahiro / Tokumaru, Sunao / Yamamoto, Michinori / Oita, Masataka

    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

    2024  Volume 120, Page(s) 103323

    Abstract: Purpose: We investigated interplay effects and treatment time (TT) in scanned proton therapy for lung cancer patients. We compared free-breathing (FB) approaches with multiple rescanning strategies and respiratory-gating (RG) methods with various gating ...

    Abstract Purpose: We investigated interplay effects and treatment time (TT) in scanned proton therapy for lung cancer patients. We compared free-breathing (FB) approaches with multiple rescanning strategies and respiratory-gating (RG) methods with various gating widths to identify the superior irradiation technique.
    Methods: Plans were created with 4/1, 2/2, and 1/4 layered/volume rescans of FB (L4V1, L2V2, and L1V4), and 50%, 30%, and 10% gating widths of the total respiratory curves (G50, G30, and G10) of the RG plans with L4V1. We calculated 4-dimensional dynamic doses assuming a constant sinusoidal curve for six irradiation methods. The reconstructed doses per fraction were compared with planned doses in terms of dose differences in 99% clinical-target-volume (CTV) (ΔD
    Results: The mean/minimum CTV ΔD
    Conclusions: FB (L4V1) is the most efficient treatment, but not necessarily the optimal choice due to interplay effects. To satisfy both TT extensions and interplay, RG with a gate width as large as possible within safety limits is desirable.
    MeSH term(s) Humans ; Lung Neoplasms ; Proton Therapy/methods ; Radiotherapy Planning, Computer-Assisted/methods ; Respiration ; Radiotherapy Dosage ; Four-Dimensional Computed Tomography/methods
    Language English
    Publishing date 2024-03-10
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1122650-x
    ISSN 1724-191X ; 1120-1797
    ISSN (online) 1724-191X
    ISSN 1120-1797
    DOI 10.1016/j.ejmp.2024.103323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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