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  1. Book: Crohn's Disease

    Rajesh, Arumugam / Sinha, Rakesh

    current concepts

    2015  

    Author's details Arumugam Rajesh ; Rakesh Sinha ed
    Language English
    Size XIV, 178 S. : Ill.
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018516125
    ISBN 978-3-319-01912-3 ; 9783319019130 ; 3-319-01912-0 ; 3319019139
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 264 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: From the Desk of the International Editor

    Rakesh Sinha

    Journal of Gastrointestinal and Abdominal Radiology, Vol 01, Iss 01, Pp 005-

    2018  Volume 005

    Keywords Internal medicine ; RC31-1245 ; Diseases of the digestive system. Gastroenterology ; RC799-869
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Article ; Online: Intestinal Imaging

    Rakesh Sinha

    Journal of Gastrointestinal and Abdominal Radiology, Vol 01, Iss 01, Pp 007-

    The Last Frontier

    2018  Volume 011

    Keywords Internal medicine ; RC31-1245 ; Diseases of the digestive system. Gastroenterology ; RC799-869
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Time-domain heart rate dynamics in the prognosis of progressive atherosclerosis.

    Kumar, Rahul / Aggarwal, Yogender / Nigam, Vinod Kumar / Sinha, Rakesh Kumar

    Nutrition, metabolism, and cardiovascular diseases : NMCD

    2024  

    Abstract: Background and aim: The regular uptake of a high-fat diet (HFD) with changing lifestyle causes atherosclerosis leading to cardiovascular diseases and autonomic dysfunction. Therefore, the current study aimed to investigate the correlation of autonomic ... ...

    Abstract Background and aim: The regular uptake of a high-fat diet (HFD) with changing lifestyle causes atherosclerosis leading to cardiovascular diseases and autonomic dysfunction. Therefore, the current study aimed to investigate the correlation of autonomic activity to lipid and atherosclerosis markers. Further, the study proposes a support vector machine (SVM) based model in the prediction of atherosclerosis severity.
    Methods and results: The Lead-II electrocardiogram and blood markers were measured from both the control and the experiment subjects each week for nine consecutive weeks. The time-domain heart rate variability (HRV) parameters were derived, and the significance level was tested using a one-way Analysis of Variance. The correlation analysis was performed to determine the relation between autonomic parameters and lipid and atherosclerosis markers. The statistically significant time-domain values were used as features of the SVM. The observed results demonstrated the reduced time domain HRV parameters with the increase in lipid and atherosclerosis index markers with the progressive atherosclerosis severity. The correlation analysis revealed a negative association between time-domain HRV parameters with lipid and atherosclerosis parameters. The percentage accuracy increases from 86.58% to 98.71% with the increase in atherosclerosis severity with regular consumption of HFD.
    Conclusions: Atherosclerosis causes autonomic dysfunction with reduced HRV. The negative correlation between autonomic parameters and lipid profile and atherosclerosis indexes marker revealed the potential role of vagal activity in the prognosis of atherosclerosis progression. The support vector machine presented a respectable accuracy in the prediction of atherosclerosis severity from the control group.
    Language English
    Publishing date 2024-01-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1067704-5
    ISSN 1590-3729 ; 0939-4753
    ISSN (online) 1590-3729
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2024.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3149: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Anesthetic Management in a 4-Year-Old Child Undergoing Removal of a Gemstone Tracheobronchial Foreign Body.

    Shelly / Kumar, Rakesh / Jayakumar, T K / Sinha, Arvind / Kumar, Sandeep

    Journal of Indian Association of Pediatric Surgeons

    2023  Volume 28, Issue 5, Page(s) 448–449

    Language English
    Publishing date 2023-09-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_78_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects.

    Sinha, Shweta / Sehgal, Alka / Ray, Sudip / Sehgal, Rakesh

    Mini reviews in medicinal chemistry

    2023  Volume 23, Issue 20, Page(s) 1928–1941

    Abstract: The benefits of honey have been recognized since ancient times for treating numerous diseases. However, in today's modern era, the use of traditional remedies has been rapidly diminishing due to the complexities of modern lifestyles. While antibiotics ... ...

    Abstract The benefits of honey have been recognized since ancient times for treating numerous diseases. However, in today's modern era, the use of traditional remedies has been rapidly diminishing due to the complexities of modern lifestyles. While antibiotics are commonly used and effective in treating pathogenic infections, their inappropriate use can lead to the development of resistance among microorganisms, resulting in their widespread prevalence. Therefore, new approaches are constantly required to combat drug-resistant microorganisms, and one practical and useful approach is the use of drug combination treatments. Manuka honey, derived from the manuka tree (Leptospermum scoparium) found exclusively in New Zealand, has garnered significant attention for its biological potential, particularly due to its antioxidant and antimicrobial properties. Moreover, when combined with antibiotics, it has demonstrated the ability to enhance their effectiveness. In this review, we delve into the chemical markers of manuka honey that are currently known, as well as detail the impact of manuka honey on the management of infectious diseases up to the present.
    MeSH term(s) Humans ; Honey ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Leptospermum/chemistry ; Communicable Diseases/drug therapy
    Chemical Substances Antioxidants ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-06-06
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2104081-3
    ISSN 1875-5607 ; 1389-5575
    ISSN (online) 1875-5607
    ISSN 1389-5575
    DOI 10.2174/1389557523666230605120717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5891: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: The Impact of Inferior Turbinate Reduction on Middle Ear Function in Adults With Nasal Obstruction.

    Prakash, Piyush / Singh, Rakesh K / Sinha, Richi

    Cureus

    2023  Volume 15, Issue 11, Page(s) e48535

    Abstract: Objective This study aims to evaluate the effect of inferior turbinate reduction on middle ear compliance and pressure. Methods A prospective observational study was conducted on 100 patients between 20 and 60 years of age with bilateral nasal ... ...

    Abstract Objective This study aims to evaluate the effect of inferior turbinate reduction on middle ear compliance and pressure. Methods A prospective observational study was conducted on 100 patients between 20 and 60 years of age with bilateral nasal obstruction due to inferior turbinate hypertrophy and a normal-looking external and middle ear. The Wilcoxon signed-rank test with a 95% confidence interval was used to compare the middle ear peak compliance and pressure on tympanometry before and one month after the inferior turbinate reduction surgery. Results The mean age was 28.44 ± 8.23 years, with a male/female ratio of 7:3. After surgery, patients with normal compliance increased by 8%, high compliance decreased by 12%, and low compliance increased by 4% in the right ear. High compliance decreased by 2%, normal compliance decreased by 10%, and low compliance increased by 12% in the left ear. Positive tympanometric peak pressure (TPP) increased by 37% and 43% in the right and left ears, respectively. Conclusion After turbinate reduction surgery, the overall tympanometric peak pressure and compliance improved. However, we did not see an obvious improvement in low middle ear compliance. Thus, turbinate reduction surgery might benefit patients with inferior turbinate hypertrophy and associated poor middle ear ventilation.
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.48535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Monitoring and Root Cause Analysis of Clinical Biochemistry Turnaround Time at a Tertiary Care Institute.

    Prasad, Priyanka / Kumar, Rakesh / Kumar, Santosh / Sinha, Poonam

    Cureus

    2023  Volume 15, Issue 6, Page(s) e39821

    Abstract: Introduction: Most laboratories around the world have focused on improving the analytical quality of laboratory tests. Laboratory turnaround time (TAT) is often left unnoticed and under-recognised in the healthcare setting. Both patients and clinicians ... ...

    Abstract Introduction: Most laboratories around the world have focused on improving the analytical quality of laboratory tests. Laboratory turnaround time (TAT) is often left unnoticed and under-recognised in the healthcare setting. Both patients and clinicians are more interested in receiving rapid, reliable, and accurate results. This can be achieved by improving the TAT through the identification of the causes that lead to delayed TAT.
    Materials and methods: This prospective study aims to identify the cause of delayed TATs within the outpatient department and implement corrective strategies to overcome them. A total of 214 samples were received. The study was conducted for a period of two years; of all the samples received, 154 were from the outpatient department, and 78 samples exceeded the expected TAT. The samples were analysed in the clinical biochemistry department of the hospital. The time spent at each station was determined using an internal computer system, which was also used to identify the samples that exceeded TATs. The primary outcome of the study was to identify the number of samples exceeding TAT and the causes of it.
    Results: Upon implementation of corrective measures and root cause analysis, the TATs were reduced from 80-88% to 11-33%. After analysing the duration of time for the samples that exceeded TAT, 45.1% and 37.5% exceeded 30 minutes in Year 1 and Year 2, respectively. Only 3.2% and 6.2% exceeded five hours in Year 1 and Year 2, respectively. Furthermore, using root cause analysis, it was found that 12% of the delay was due to increased waiting time or sample collection, 14% included other causes such as outsourcing of samples, and 18% of the delay was due to pre-analytic processing time.
    Conclusion: Our study concludes that TAT is an important quality assessment tool within the laboratory setting, and with proper identification of causes, it can be improved. Although monitoring TAT is a tedious process that mandates tremendous efforts, with the presence of real-time monitoring, improving TAT is an achievable goal. This, in turn, can improve patient treatment outcomes and clinician satisfaction.
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.39821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Balancing potential benefits and ethical considerations of gene editing.

    Ghosh, Shampa / Ghosh, Soumya / Raghunath, Manchala / Bhaskar, Rakesh / Sinha, Jitendra Kumar

    Lancet (London, England)

    2023  Volume 401, Issue 10394, Page(s) 2109–2110

    MeSH term(s) Humans ; Gene Editing
    Language English
    Publishing date 2023-06-24
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)01084-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.5: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 94: Show issues

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  10. Article ; Online: Assessing the impacts of land use/land cover and climate change on surface runoff of a humid tropical river basin in Western Ghats, India

    Sinha, Rakesh Kumar / Eldho, T. I. / Subimal, Ghosh

    International Journal of River Basin Management. 2023 Apr. 03, v. 21, no. 2 p.141-152

    2023  

    Abstract: In this study, the impacts of changes in land use/ land cover (LULC) and climate on surface runoff are investigated in the Kadalundi river basin, Western Ghats, India. Land Change Modeller (LCM) was applied to project the future LULC scenarios in 2030 ... ...

    Abstract In this study, the impacts of changes in land use/ land cover (LULC) and climate on surface runoff are investigated in the Kadalundi river basin, Western Ghats, India. Land Change Modeller (LCM) was applied to project the future LULC scenarios in 2030 and 2050. Climate change scenarios of the future time period of near (2011−2040), mid (2041−2070), and far (2071−2099) were procured for Representative Concentration Pathway (RCP) 4.5 and 8.5 emission scenarios from five different general circulation models of coordinated regional downscaled experiment project. The 1988 and 2000 LULC were used for projection of 2014 LULC and validated with actual 2014 LULC. Further, 2000 and 2014 LULC were used for projection of 2030 LULC, and 2014 and 2030 LULC were used to project 2050 LULC. Changes in LULC from 2000 to 2050 are calculated using the transition matrix approach. The impacts of changes in LULC and climate on surface runoff are investigated by the Soil and Water Assessment Tool (SWAT) model. The results showed a decrease in forest and grassland and an increase in agriculture, and urban areas from 2000 to 2050, with an increase in the mean annual surface runoff. For climate change scenarios assessed, mean annual surface runoff in the near, mid, and far would be decreasing under both RCP 4.5 and 8.5 while RCP 8.5 showing more worse condition than RCP 4.5 in the future. The combined effects of changes in LULC and climate showed a decreasing trend in the surface runoff for the near and mid future. Furthermore, the projected results indicate that the surface runoff would be higher in both RCP scenarios during winter and summer; while the monsoon period largely demonstrates a reverse trend. The analysis of combined impacts reveals that the decreasing of surface runoff under RCP 4.5 and 8.5 would be higher in near compared to mid future.
    Keywords Soil and Water Assessment Tool model ; administrative management ; climate ; climate change ; forests ; grasslands ; land cover ; land use ; monsoon season ; runoff ; summer ; watersheds ; winter ; India ; LULC ; SWAT modelling ; surface runoff
    Language English
    Dates of publication 2023-0403
    Size p. 141-152.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2568945-9
    ISSN 1814-2060 ; 1571-5124
    ISSN (online) 1814-2060
    ISSN 1571-5124
    DOI 10.1080/15715124.2020.1809434
    Database NAL-Catalogue (AGRICOLA)

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