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  1. Book ; Online ; E-Book: Metastatic disease of the nervous system

    Schiff, David / Bent, Martin J. van den

    (Handbook of clinical neurology ; 149)

    2018  

    Author's details volume editors David Schiff and Martin J. van den Bent
    Series title Handbook of clinical neurology ; 149
    Collection
    Language English
    Size 1 Online-Ressource (xiv, 287 Seiten), Illustrationen, Diagramme
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019654955
    ISBN 978-0-444-63879-3 ; 9780128111611 ; 0-444-63879-2 ; 0128111615
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article ; Online: What is a glioblastoma?

    Lassman, Andrew B / van den Bent, Martin J

    Neuro-oncology

    2023  Volume 25, Issue 6, Page(s) 1015–1016

    MeSH term(s) Humans ; Glioblastoma ; Brain Neoplasms/therapy
    Language English
    Publishing date 2023-02-14
    Publishing country England
    Document type Editorial
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noad044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5307: Show issues Location:
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  3. Article ; Online: Autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L) in glioblastoma: Breakthrough or fata morgana?

    Preusser, Matthias / van den Bent, Martin J

    Neuro-oncology

    2022  Volume 25, Issue 4, Page(s) 631–634

    MeSH term(s) Humans ; Glioblastoma ; Vaccination ; Dendritic Cells ; Cancer Vaccines
    Chemical Substances Cancer Vaccines
    Language English
    Publishing date 2022-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noac281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: H3 K27M-altered glioma and diffuse intrinsic pontine glioma: Semi-systematic review of treatment landscape and future directions.

    van den Bent, Martin / Saratsis, Amanda M / Geurts, Marjolein / Franceschi, Enrico

    Neuro-oncology

    2024  Volume 26, Issue Supplement_2, Page(s) S110–S124

    Abstract: H3 K27M-mutant diffuse glioma is a recently identified brain tumor associated with poor prognosis. As of 2016, it is classified by the World Health Organization as a distinct form of grade IV glioma. Despite recognition as an important prognostic and ... ...

    Abstract H3 K27M-mutant diffuse glioma is a recently identified brain tumor associated with poor prognosis. As of 2016, it is classified by the World Health Organization as a distinct form of grade IV glioma. Despite recognition as an important prognostic and diagnostic feature in diffuse glioma, radiation remains the sole standard of care and no effective systemic therapies are available for H3K27M mutant tumors. This review will detail treatment interventions applied to diffuse midline glioma and diffuse intrinsic pontine glioma (DIPG) prior to the identification of the H3 K27M mutation, the current standard-of-care for H3 K27M-mutant diffuse glioma treatment, and ongoing clinical trials listed on www.clinicaltrials.gov evaluating novel therapeutics in this population. Current clinical trials were identified using clinicaltrials.gov, and studies qualifying for this analysis were active or ongoing interventional trials that evaluated a therapy in at least 1 treatment arm or cohort comprised exclusively of patients with DIPG and H3 K27M-mutant glioma. Forty-one studies met these criteria, including trials evaluating H3 K27M vaccination, chimeric antigen receptor T-cell therapy, and small molecule inhibitors. Ongoing evaluation of novel therapeutics is necessary to identify safe and effective interventions in this underserved patient population.
    MeSH term(s) Humans ; Brain Stem Neoplasms/therapy ; Brain Stem Neoplasms/genetics ; Brain Stem Neoplasms/pathology ; Diffuse Intrinsic Pontine Glioma/therapy ; Diffuse Intrinsic Pontine Glioma/genetics ; Diffuse Intrinsic Pontine Glioma/pathology ; Glioma/genetics ; Glioma/therapy ; Glioma/pathology ; Mutation ; Histones/genetics ; Prognosis ; Brain Neoplasms/therapy ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology
    Chemical Substances Histones
    Language English
    Publishing date 2024-05-01
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noad220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5307: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: Hypermutated recurrences: Identifying the clinical relevance.

    Geurts, Marjolein / van den Bent, Martin J

    Neuro-oncology

    2021  Volume 23, Issue 11, Page(s) 1805–1806

    MeSH term(s) Humans ; Mutation ; Recurrence
    Language English
    Publishing date 2021-08-28
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noab192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5307: Show issues Location:
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  6. Article ; Online: What is an isocitrate dehydrogenase-mutated central nervous system World Health Organization grade 2 glioma, or who should receive vorasidenib?

    Preusser, Matthias / Geurts, Marjolein / Hainfellner, Johannes A / van den Bent, Martin J

    Neuro-oncology

    2023  Volume 25, Issue 11, Page(s) 1915–1917

    MeSH term(s) Humans ; Isocitrate Dehydrogenase/genetics ; Glioma ; Central Nervous System ; World Health Organization ; Mutation ; Brain Neoplasms
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41) ; vorasidenib
    Language English
    Publishing date 2023-07-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noad113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: RANO 2.0: The revised Response Assessment in Neuro-Oncology (RANO) criteria for high- and low-grade glial tumors in adults designed for the future.

    Wen, Patrick Y / van den Bent, Martin / Vogelbaum, Michael A / Chang, Susan M

    Neuro-oncology

    2023  Volume 26, Issue 1, Page(s) 2–4

    MeSH term(s) Adult ; Humans ; Glioma ; Brain Neoplasms/therapy
    Language English
    Publishing date 2023-09-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noad189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5307: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: The potential of amino acid PET imaging for prediction and monitoring of vorasidenib response in IDH-mutant gliomas.

    Albert, Nathalie L / Furtner, Julia / van den Bent, Martin J / Preusser, Matthias

    Neuro-oncology

    2023  Volume 26, Issue 3, Page(s) 403–406

    MeSH term(s) Humans ; Amino Acids ; Glioma/diagnostic imaging ; Glioma/drug therapy ; Glioma/genetics ; Positron-Emission Tomography ; Diamines ; Isocitrate Dehydrogenase/genetics ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/drug therapy ; Brain Neoplasms/genetics ; Mutation ; Pyridines
    Chemical Substances vorasidenib ; Amino Acids ; Diamines ; Isocitrate Dehydrogenase (EC 1.1.1.41) ; Pyridines
    Language English
    Publishing date 2023-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noad240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma - Authors' reply.

    van den Bent, Martin J / Tesileanu, Mircea

    The Lancet. Oncology

    2021  Volume 22, Issue 8, Page(s) e346

    MeSH term(s) Glioma/drug therapy ; Glioma/genetics ; Humans ; Isocitrate Dehydrogenase ; Temozolomide/adverse effects
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41) ; Temozolomide (YF1K15M17Y)
    Language English
    Publishing date 2021-08-02
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(21)00418-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5696: Show issues Location:
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    Zs.MO 460: Show issues

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  10. Article ; Online: Fast-growing oligodendrogliomas are aggressive tumors-the real life biomarker?

    Geurts, Marjolein / van den Bent, Martin J

    Neuro-oncology

    2020  Volume 22, Issue 7, Page(s) 907–908

    MeSH term(s) Adult ; Biomarkers ; Brain Neoplasms ; Humans ; Oligodendroglioma
    Chemical Substances Biomarkers
    Language English
    Publishing date 2020-04-15
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noaa097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5307: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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