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  1. Article ; Online: Recent trends on omics and bioinformatics approaches to study SARS-CoV-2: A bibliometric analysis and mini-review.

    Murillo, Julieth / Villegas, Lina María / Ulloa-Murillo, Leidy Marcela / Rodríguez, Alejandra Rocío

    Computers in biology and medicine

    2020  Volume 128, Page(s) 104162

    Abstract: Background: The successful sequencing of SARS-CoV-2 cleared the way for the use of omics technologies and integrative biology research for combating the COVID-19 pandemic. Currently, many research groups have slowed down their respective projects to ... ...

    Abstract Background: The successful sequencing of SARS-CoV-2 cleared the way for the use of omics technologies and integrative biology research for combating the COVID-19 pandemic. Currently, many research groups have slowed down their respective projects to concentrate efforts in the study of the biology of SARS-CoV-2. In this bibliometric analysis and mini-review, we aimed to describe how computational methods or omics approaches were used during the first months of the COVID-19 pandemic.
    Methods: We analyzed bibliometric data from Scopus, BioRxiv, and MedRxiv (dated June 19th, 2020) using quantitative and knowledge mapping approaches. We complemented our analysis with a manual process of carefully reading the selected articles to identify either the omics or bioinformatic tools used and their purpose.
    Results: From a total of 184 articles, we found that metagenomics and transcriptomics were the main sources of data to perform phylogenetic analysis aimed at corroborating zoonotic transmission, identifying the animal origin and taxonomic allocation of SARS-CoV-2. Protein sequence analysis, immunoinformatics and molecular docking were used to give insights about SARS-CoV-2 targets for drug and vaccine development. Most of the publications were from China and USA. However, China, Italy and India covered the top 10 most cited papers on this topic.
    Conclusion: We found an abundance of publications using omics and bioinformatics approaches to establish the taxonomy and animal origin of SARS-CoV-2. We encourage the growing community of researchers to explore other lesser-known aspects of COVID-19 such as virus-host interactions and host response.
    MeSH term(s) Bibliometrics ; COVID-19/epidemiology ; COVID-19/genetics ; COVID-19/metabolism ; Computational Biology ; Humans ; Molecular Docking Simulation ; Pandemics ; Phylogeny ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism
    Language English
    Publishing date 2020-12-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2020.104162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Immune Profile of the Nasal Mucosa in Patients with Cutaneous Leishmaniasis.

    Gómez-Zafra, María J / Navas, Adriana / Jojoa, Jimena / Murillo, Julieth / González, Camila / Gómez, María Adelaida

    Infection and immunity

    2020  Volume 88, Issue 5

    Abstract: Localized skin lesions are characteristic of cutaneous leishmaniasis (CL); however, ...

    Abstract Localized skin lesions are characteristic of cutaneous leishmaniasis (CL); however,
    MeSH term(s) Adult ; Antigens, CD/immunology ; Cell Adhesion Molecules/immunology ; Female ; Humans ; Interleukin-4 Receptor alpha Subunit/immunology ; Interleukin-5 Receptor alpha Subunit/immunology ; Leishmania/immunology ; Leishmaniasis, Cutaneous/immunology ; Male ; Matrix Attachment Region Binding Proteins/immunology ; Nasal Mucosa/immunology ; Skin/immunology ; Transcriptome/immunology
    Chemical Substances Antigens, CD ; Cell Adhesion Molecules ; Interleukin-4 Receptor alpha Subunit ; Interleukin-5 Receptor alpha Subunit ; Matrix Attachment Region Binding Proteins
    Language English
    Publishing date 2020-04-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00881-19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Psychological Violence in the Romantic Relationships of University Students from Quibdó, Chocó

    Elizabeth Montoya Giraldo / Julieth Andrea Pinillo Gómez / Laura Mosquera Sánchez / Yenifel Andrea Raga Murillo / Cindy Paola Moya Salina / Yiris Vanessa Ledesma Pino / Diany Marcela Gutiérrez Ibargüen

    RHS Revista Humanismo y Sociedad, Vol 11, Iss 2, Pp 1-

    2023  Volume 13

    Abstract: Psychological violence in romantic relationships is a method of subjection of one person to another that is naturalized by relating violence to the physicality of the body, ignoring its effects on mental health. Therefore, the main objective of this ... ...

    Abstract Psychological violence in romantic relationships is a method of subjection of one person to another that is naturalized by relating violence to the physicality of the body, ignoring its effects on mental health. Therefore, the main objective of this study was to describe psychological violence in the relationships of young university students in the city of Quibdó. The methodology of the study is quantitative, a Scale of Violence in Adolescent Relationships (CADRI) was applied to measure the components associated with psychological violence: relational, verbal-emotional violence and threat. The sample was made up of 240 university students, of which 130 were students from Uniclaretiana (private university) and 110 from Universidad Tecnológica del Chocó Diego Luis Córdoba (public university). The results evidenced that the most predominant type of violence among university students is the verbal-emotional violence, and women are the most likely to exercise it and suffer it within relationships. Another relevant finding is that private university students suffer and experience violence in a higher percentage, excluding the relational violence suffered.
    Keywords gender-based violence ; psychological violence ; couple relationships ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Corporación Universitaria Remington
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Early Leukocyte Responses in

    Gomez, Maria Adelaida / Belew, Ashton Trey / Navas, Adriana / Rosales-Chilama, Mariana / Murillo, Julieth / Dillon, Laura A L / Alexander, Theresa A / Martinez-Valencia, Alvaro / El-Sayed, Najib M

    Frontiers in cellular and infection microbiology

    2021  Volume 11, Page(s) 687607

    Abstract: Early host-pathogen interactions drive the host response and shape the outcome of natural infections caused by intracellular microorganisms. These interactions involve a number of immune and non-immune cells and tissues, along with an assortment of host ... ...

    Abstract Early host-pathogen interactions drive the host response and shape the outcome of natural infections caused by intracellular microorganisms. These interactions involve a number of immune and non-immune cells and tissues, along with an assortment of host and pathogen-derived molecules. Our current knowledge has been predominantly derived from research on the relationships between the pathogens and the invaded host cell(s), limiting our understanding of how microbes elicit and modulate immunological responses at the organismal level. In this study, we explored the early host determinants of healing and non-healing responses in human cutaneous leishmaniasis (CL) caused by
    MeSH term(s) Humans ; Leishmania ; Leishmania guyanensis ; Leishmaniasis, Cutaneous ; Leukocytes ; Leukocytes, Mononuclear
    Language English
    Publishing date 2021-09-07
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2021.687607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Profiles of Local and Systemic Inflammation in the Outcome of Treatment of Human Cutaneous Leishmaniasis Caused by

    Navas, Adriana / Fernández, Olga / Gallego-Marín, Carolina / Castro, María Del Mar / Rosales-Chilama, Mariana / Murillo, Julieth / Cossio, Alexandra / McMahon-Pratt, Diane / Saravia, Nancy Gore / Gómez, María Adelaida

    Infection and immunity

    2020  Volume 88, Issue 3

    Abstract: The immune mechanisms that contribute to the efficacy of treatment of cutaneous leishmaniasis (CL) are not fully understood. The aim of this study was to define immune correlates of the outcome of treatment of CL caused ... ...

    Abstract The immune mechanisms that contribute to the efficacy of treatment of cutaneous leishmaniasis (CL) are not fully understood. The aim of this study was to define immune correlates of the outcome of treatment of CL caused by
    MeSH term(s) Antiprotozoal Agents/therapeutic use ; Cytokines/metabolism ; Gene Expression Profiling ; Humans ; Immunity, Innate/physiology ; Leishmania/immunology ; Leishmaniasis/drug therapy ; Leishmaniasis/immunology ; Leishmaniasis/metabolism ; Leukocytes, Mononuclear/metabolism ; Meglumine Antimoniate/therapeutic use ; Monocyte Chemoattractant Proteins/metabolism ; Monocytes/metabolism
    Chemical Substances Antiprotozoal Agents ; Cytokines ; Monocyte Chemoattractant Proteins ; Meglumine Antimoniate (75G4TW236W)
    Language English
    Publishing date 2020-02-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00764-19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: Business intelligence and financial decision-making

    Mary Julieth Murillo Junco / Gustavo Cáceres Castellanos

    Logos Ciencia & Tecnología, Vol 5, Iss 1, Pp 119-

    a theoretical approach

    2013  Volume 138

    Abstract: This paper deals with a literature review about the origin, development and implementation of Business Intelligence focused directly to solving problems in the financial area of the different organizations. Wanted contextualize how it tools have been ... ...

    Abstract This paper deals with a literature review about the origin, development and implementation of Business Intelligence focused directly to solving problems in the financial area of the different organizations. Wanted contextualize how it tools have been incorporated into the decision making processes of modern business. A feature of the way it makes decisions has to do with the rational use made of the information available, and it is in this field where information technology and communication play a role today
    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Language Spanish
    Publishing date 2013-01-01T00:00:00Z
    Publisher Policía Nacional de Colombia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: The reactome pathway knowledgebase 2022.

    Gillespie, Marc / Jassal, Bijay / Stephan, Ralf / Milacic, Marija / Rothfels, Karen / Senff-Ribeiro, Andrea / Griss, Johannes / Sevilla, Cristoffer / Matthews, Lisa / Gong, Chuqiao / Deng, Chuan / Varusai, Thawfeek / Ragueneau, Eliot / Haider, Yusra / May, Bruce / Shamovsky, Veronica / Weiser, Joel / Brunson, Timothy / Sanati, Nasim /
    Beckman, Liam / Shao, Xiang / Fabregat, Antonio / Sidiropoulos, Konstantinos / Murillo, Julieth / Viteri, Guilherme / Cook, Justin / Shorser, Solomon / Bader, Gary / Demir, Emek / Sander, Chris / Haw, Robin / Wu, Guanming / Stein, Lincoln / Hermjakob, Henning / D'Eustachio, Peter

    Nucleic acids research

    2021  Volume 50, Issue D1, Page(s) D687–D692

    Abstract: The Reactome Knowledgebase (https://reactome.org), an Elixir core resource, provides manually curated molecular details across a broad range of physiological and pathological biological processes in humans, including both hereditary and acquired disease ... ...

    Abstract The Reactome Knowledgebase (https://reactome.org), an Elixir core resource, provides manually curated molecular details across a broad range of physiological and pathological biological processes in humans, including both hereditary and acquired disease processes. The processes are annotated as an ordered network of molecular transformations in a single consistent data model. Reactome thus functions both as a digital archive of manually curated human biological processes and as a tool for discovering functional relationships in data such as gene expression profiles or somatic mutation catalogs from tumor cells. Recent curation work has expanded our annotations of normal and disease-associated signaling processes and of the drugs that target them, in particular infections caused by the SARS-CoV-1 and SARS-CoV-2 coronaviruses and the host response to infection. New tools support better simultaneous analysis of high-throughput data from multiple sources and the placement of understudied ('dark') proteins from analyzed datasets in the context of Reactome's manually curated pathways.
    MeSH term(s) Antiviral Agents/pharmacology ; COVID-19/metabolism ; Data Curation ; Genome, Human ; Host-Pathogen Interactions ; Humans ; Knowledge Bases ; Proteins/genetics ; Proteins/metabolism ; Signal Transduction ; Software
    Chemical Substances Antiviral Agents ; Proteins
    Language English
    Publishing date 2021-11-03
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 186809-3
    ISSN 1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
    ISSN (online) 1362-4962 ; 1362-4954
    ISSN 0301-5610 ; 0305-1048
    DOI 10.1093/nar/gkab1028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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