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  1. Article: Evaluating Biological Properties of Stingless Bee Propolis.

    Lim, Jin Ru / Chua, Lee Suan / Dawood, Dawood Ali Salim

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 12

    Abstract: The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee ( ...

    Abstract The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee (
    Language English
    Publishing date 2023-06-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12122290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Microwave Dual-Crack Sensor with a High Q-Factor Using the TE

    Kim, Yelim / Park, Eiyong / Salim, Ahmed / Kim, Junghyeon / Lim, Sungjoon

    Micromachines

    2023  Volume 14, Issue 3

    Abstract: Microwave sensors have attracted interest as non-destructive metal crack detection (MCD) devices due to their low cost, simple fabrication, potential miniaturization, noncontact nature, and capability for remote detection. However, the development of ... ...

    Abstract Microwave sensors have attracted interest as non-destructive metal crack detection (MCD) devices due to their low cost, simple fabrication, potential miniaturization, noncontact nature, and capability for remote detection. However, the development of multi-crack sensors of a suitable size and quality factor (Q-factor) remains a challenge. In the present study, we propose a multi-MCD sensor that combines a higher-mode substrate-integrated waveguide (SIW) and complementary split-ring resonators (CSRRs). In order to increase the Q-factor, the device is miniaturized; the MCD is facilitated; and two independent CSRRs are loaded onto the SIW, where the electromagnetic field is concentrated. The concentrated electromagnetic field of the SIW improves the Q-factor of the CSRRs, and each CSRR creates its own resonance and produces a miniaturizing effect by activating the sensor below the cut-off frequency of the SIW. The proposed multi-MCD sensor is numerically and experimentally demonstrated for cracks with different widths and depths. The fabricated sensor with a TE
    Language English
    Publishing date 2023-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14030578
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Untersuchungen zur Nierenverträglichkeit von Vancomycin mit Hilfe monoklonaler Antikörper

    Lim, Salim

    1994  

    Author's details vorgelegt von Salim Lim
    Language German
    Size 87 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 1994
    Note Mikrofiche-Ausg.: 1 Mikrofiche : 24x
    HBZ-ID HT006813099
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1995 MB 2767 order for loan Magazin

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  4. Article ; Online: TM

    Salim, Ahmed / Lim, Sungjoon

    Sensors (Basel, Switzerland)

    2018  Volume 18, Issue 6

    Abstract: The detection of multiple fluids using a single chip has been attracting attention recently. A ... ...

    Abstract The detection of multiple fluids using a single chip has been attracting attention recently. A TM
    Language English
    Publishing date 2018-06-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s18061964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Millimeter-Wave-Based Spoof Localized Surface Plasmonic Resonator for Sensing Glucose Concentration.

    Kim, Yelim / Salim, Ahmed / Lim, Sungjoon

    Biosensors

    2021  Volume 11, Issue 10

    Abstract: Glucose-monitoring sensors are necessary and have been extensively studied to prevent and control health problems caused by diabetes. Spoof localized surface plasmon (LSP) resonance sensors have been investigated for chemical sensing and biosensing. A ... ...

    Abstract Glucose-monitoring sensors are necessary and have been extensively studied to prevent and control health problems caused by diabetes. Spoof localized surface plasmon (LSP) resonance sensors have been investigated for chemical sensing and biosensing. A spoof LSP has similar characteristics to an LSP in the microwave or terahertz frequency range but with certain advantages, such as a high-quality factor and improved sensitivity. In general, microwave spoof LSP resonator-based glucose sensors have been studied. In this study, a millimeter-wave-based spoof surface plasmonic resonator sensor is designed to measure glucose concentrations. The millimeter-wave-based sensor has a smaller chip size and higher sensitivity than microwave-frequency sensors. Therefore, the microfluidic channel was designed to be reusable and able to operate with a small sample volume. For alignment, a polydimethylsiloxane channel was simultaneously fabricated using a multilayer bonding film to attach the upper side of the pattern, which is concentrated in the electromagnetic field. This real-time sensor detects the glucose concentration via changes in the S11 parameter and operates at 28 GHz with an average sensitivity of 0.015669 dB/(mg/dL) within the 0-300 mg/dL range. The minimum detectable concentration and the distinguishable signal are 1 mg/dL and 0.015669 dB, respectively, from a 3.4 μL sample. The reusability and reproducibility were assessed through replicates.
    MeSH term(s) Biosensing Techniques ; Blood Glucose ; Equipment Design ; Microfluidics ; Microwaves ; Reproducibility of Results ; Surface Plasmon Resonance
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2021-09-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios11100358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Recent advances in noninvasive flexible and wearable wireless biosensors.

    Salim, Ahmed / Lim, Sungjoon

    Biosensors & bioelectronics

    2019  Volume 141, Page(s) 111422

    Abstract: Flexible and wearable biosensors have great potential to interface with skin and noninvasively extract biofluids for real time and continuous monitoring of physiological status. Soft electronics is the prime factor in these wearables, regardless of ... ...

    Abstract Flexible and wearable biosensors have great potential to interface with skin and noninvasively extract biofluids for real time and continuous monitoring of physiological status. Soft electronics is the prime factor in these wearables, regardless of sensing mechanism and fabrication technology. Wireless connectivity would be a valuable addition to enhance wearable biosensor's scope for remote and resource limited settings. These skin-adaptable, user-friendly, battery-free (although not all), and noninvasive devices continuously and simultaneously monitor wearer well-being and transfer data wirelessly. Thus, they have a great potential to improve quality of life with timely diagnostics and hence early treatments. However, they remain in the early stages, with relatively conventional sensing modalities, battery requirements, soft electronics fabrication limitations, and practicable size restrictions to retain skin compatibility. We classify wearable biosensors by sensing functionality, such as skin temperature, pH, heart rate, sweat glucose, uric acid, sweat electrolyte, cerebrospinal shunt flow, and toxic chemicals, and discuss challenges and prospects for these biosensors.
    MeSH term(s) Animals ; Biosensing Techniques/instrumentation ; Biosensing Techniques/methods ; Equipment Design ; Glucose/analysis ; Heart Rate ; Humans ; Monitoring, Physiologic/instrumentation ; Monitoring, Physiologic/methods ; Skin Temperature ; Sweat/chemistry ; Wearable Electronic Devices ; Wireless Technology/instrumentation
    Chemical Substances Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2019-06-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2019.111422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2275: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Review of Recent Metamaterial Microfluidic Sensors.

    Salim, Ahmed / Lim, Sungjoon

    Sensors (Basel, Switzerland)

    2018  Volume 18, Issue 1

    Abstract: Metamaterial elements/arrays exhibit a sensitive response to fluids yet with a small footprint, therefore, they have been an attractive choice to realize various sensing devices when integrated with microfluidic technology. Micro-channels made from ... ...

    Abstract Metamaterial elements/arrays exhibit a sensitive response to fluids yet with a small footprint, therefore, they have been an attractive choice to realize various sensing devices when integrated with microfluidic technology. Micro-channels made from inexpensive biocompatible materials avoid any contamination from environment and require only microliter-nanoliter sample for sensing. Simple design, easy fabrication process, light weight prototype, and instant measurements are advantages as compared to conventional (optical, electrochemical and biological) sensing systems. Inkjet-printed flexible sensors find their utilization in rapidly growing wearable electronics and health-monitoring flexible devices. Adequate sensitivity and repeatability of these low profile microfluidic sensors make them a potential candidate for point-of-care testing which novice patients can use reliably. Aside from degraded sensitivity and lack of selectivity in all practical microwave chemical sensors, they require an instrument, such as vector network analyzer for measurements and not readily available as a self-sustained portable sensor. This review article presents state-of-the-art metamaterial inspired microfluidic bio/chemical sensors (passive devices ranging from gigahertz to terahertz range) with an emphasis on metamaterial sensing circuit and microfluidic detection. We also highlight challenges and strategies to cope these issues which set future directions.
    Language English
    Publishing date 2018-01-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s18010232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Recent advances in the metamaterial-inspired biosensors.

    Salim, Ahmed / Lim, Sungjoon

    Biosensors & bioelectronics

    2018  Volume 117, Page(s) 398–402

    Abstract: Metamaterials (MM)-inspired microwave biosensors are a valuable addition to the field of diagnostic approaches and prognostic tools. The fundamental principle behind these biosensors is unique dielectric signatures corresponding to healthy/diseased ... ...

    Abstract Metamaterials (MM)-inspired microwave biosensors are a valuable addition to the field of diagnostic approaches and prognostic tools. The fundamental principle behind these biosensors is unique dielectric signatures corresponding to healthy/diseased tissues. Relying on nonionizing radiation and offering an increased resolution with accuracy comparable to that of ultrasound devices, they are an attractive solution for noninvasive and label-free biosensing applications. High-quality-factor MM-inspired resonators are integrated with microfluidics to accelerate the lab-on-chip and point-of-care diagnostic approaches owing to the small detection volume and overall compact size of these devices. A variety of biomolecular detection, glucose detection and hyperthermia treatment using state-of-the-art MM-inspired biosensors have been discussed. Optical transduction techniques (e.g., surface plasmon resonance) which enhance the sensitivity in terms of limit-of-detection and resolution, have also been outlined. Utilization of microwave biosensors as therapeutic agents is at its initial stages owing to lack of required sensitivity and reliability in recently proposed MM-inspired biosensors.
    MeSH term(s) Biosensing Techniques/trends ; Diagnostic Techniques and Procedures/instrumentation ; Diagnostic Techniques and Procedures/trends ; Microfluidics ; Microwaves ; Oligonucleotide Array Sequence Analysis ; Reproducibility of Results ; Surface Plasmon Resonance
    Language English
    Publishing date 2018-06-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2018.06.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2275: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: The SingHealth Perioperative and Anesthesia Subject Area Registry (PASAR), a large-scale perioperative data mart and registry.

    Abdullah, Hairil Rizal / Lim, Daniel Yan Zheng / Ke, Yuhe / Salim, Nur Nasyitah Mohamed / Lan, Xiang / Dong, Yizhi / Feng, Mengling

    Korean journal of anesthesiology

    2023  Volume 77, Issue 1, Page(s) 58–65

    Abstract: Background: To enhance perioperative outcomes, a perioperative registry that integrates high-quality real-world data throughout the perioperative period is essential. Singapore General Hospital established the Perioperative and Anesthesia Subject Area ... ...

    Abstract Background: To enhance perioperative outcomes, a perioperative registry that integrates high-quality real-world data throughout the perioperative period is essential. Singapore General Hospital established the Perioperative and Anesthesia Subject Area Registry (PASAR) to unify data from the preoperative, intraoperative, and postoperative stages. This study presents the methodology employed to create this database.
    Methods: Since 2016, data from surgical patients have been collected from the hospital electronic medical record systems, de-identified, and stored securely in compliance with privacy and data protection laws. As a representative sample, data from initiation in 2016 to December 2022 were collected.
    Results: As of December 2022, PASAR data comprise 26 tables, encompassing 153,312 patient admissions and 168,977 operation sessions. For this period, the median age of the patients was 60.0 years, sex distribution was balanced, and the majority were Chinese. Hypertension and cardiovascular comorbidities were also prevalent. Information including operation type and time, intensive care unit (ICU) length of stay, and 30-day and 1-year mortality rates were collected. Emergency surgeries resulted in longer ICU stays, but shorter operation times than elective surgeries.
    Conclusions: The PASAR provides a comprehensive and automated approach to gathering high-quality perioperative patient data.
    MeSH term(s) Humans ; Middle Aged ; Data Warehousing ; Elective Surgical Procedures ; Patient Admission ; Anesthesia ; Registries
    Language English
    Publishing date 2023-11-08
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2557340-8
    ISSN 2005-7563 ; 2005-7563
    ISSN (online) 2005-7563
    ISSN 2005-7563
    DOI 10.4097/kja.23580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Associations Between Mean HbA1c, HbA1c Variability, and Both Mortality and Macrovascular Complications in Patients with Diabetes Mellitus: A Registry-Based Cohort Study.

    Tan, Joshua Kuan / Lim, Gek Hsiang / Mohamed Salim, Nur Nasyitah / Chia, Sing Yi / Thumboo, Julian / Bee, Yong Mong

    Clinical epidemiology

    2023  Volume 15, Page(s) 137–149

    Abstract: Background: We investigate the association between mean HbA1c, HbA1c variability, and all-cause mortality and diabetes-related macrovascular complications in patients with diabetes.: Methods: We performed a retrospective cohort study using patients ... ...

    Abstract Background: We investigate the association between mean HbA1c, HbA1c variability, and all-cause mortality and diabetes-related macrovascular complications in patients with diabetes.
    Methods: We performed a retrospective cohort study using patients present in the Singapore Health Services diabetes registry (SDR) during 2013 to 2014. We assessed mean HbA1c using three models: a baseline mean HbA1c for 2013-14, the mean across the whole follow-up period, and a time-varying yearly updated mean. We assessed HbA1c variability at baseline using the patient's HbA1c variability score (HVS) for 2013-14. The association between mean HbA1c, HVS, and 6 outcomes were assessed using Cox proportional hazard models.
    Results: We included 43,837-53,934 individuals in the analysis; 99.3% had type 2 diabetes mellitus. The data showed a J-shaped distribution in adjusted hazard ratios (HRs) for all-cause mortality, ischemic heart disease, acute myocardial infarction, peripheral arterial disease, and ischemic stroke, with an increased risk of developing these outcomes at HbA1c <6% (42 mmol/mol) and ≥8% (64 mmol/mol). With the addition of HVS, the J-shaped distribution was maintained for the above outcomes, but HRs were greater at HbA1c <6.0% (42 mmol/mol) and reduced at HbA1c ≥8.0% (64 mmol/mol) when compared to models without HVS. The risk for all outcomes increased substantially with increasing glycaemic variability.
    Conclusion: Both low (<6.0% [42 mmol/mol]) and high (≥8.0% [64 mmol/mol]) levels of glycaemic control are associated with increased all-cause mortality and diabetes-related macrovascular complications. Glycaemic variability is independently associated with increased risk for these outcomes. Therefore, patients with stable glycaemic level of 6-8% (42-64mmol/mol) are at lowest risk of all-cause mortality and diabetes-related macrovascular complications.
    Language English
    Publishing date 2023-01-25
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494772-6
    ISSN 1179-1349
    ISSN 1179-1349
    DOI 10.2147/CLEP.S391749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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