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  1. AU=Martin Rick
  2. AU="Narges ROUSTAEI"
  3. AU="Alsaady, Ammar"
  4. AU=Guo Zhinian
  5. AU=Dho Sascha E
  6. AU="Santiso-Quiñones, Gustavo"
  7. AU="Donovan, Lois E"
  8. AU="Xiong, Zhuo-Chao"
  9. AU="Mu, Dezhi"
  10. AU="Kaiser, Steffen"
  11. AU=Garlepp M J
  12. AU=Yang Zhenwei
  13. AU="Guillot, Loic"
  14. AU=Pocrnic Ivan
  15. AU="Rackova, Sylva"
  16. AU="Jordan Denizeau"
  17. AU="Alexandra J. Corbett"
  18. AU="Felderman, Howard E"
  19. AU="Chen, Fuxing"
  20. AU="Soekadar, Surjo R"
  21. AU="Pagotto, Sara"
  22. AU="Dominguez, Georgina Cutillas"
  23. AU=Barabutis Nektarios
  24. AU="Rumalla, Kavelin"
  25. AU=Meares Gordon P.
  26. AU="Gawron, Lori M"
  27. AU=Guettari Moez
  28. AU=Ma Xingcong
  29. AU="Greene, Kerrie" AU="Greene, Kerrie"
  30. AU="Adebayo, Abe"
  31. AU=Amoako Yaw Ampem
  32. AU="Khanna, Sakshum"

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  1. Buch ; Online: RICK

    Tiwari, Deepika / Monperrus, Martin / Baudry, Benoit

    Generating Mocks from Production Data

    2023  

    Abstract: ... However, implementing test doubles within tests is not straightforward. With this demonstration, we introduce RICK ... and stubs. RICK monitors the invocation of target methods and their interactions with external ... components. Based on the data collected from these observations, RICK produces unit tests with mocks, stubs ...

    Abstract Test doubles, such as mocks and stubs, are nifty fixtures in unit tests. They allow developers to test individual components in isolation from others that lie within or outside of the system. However, implementing test doubles within tests is not straightforward. With this demonstration, we introduce RICK, a tool that observes executing applications in order to automatically generate tests with realistic mocks and stubs. RICK monitors the invocation of target methods and their interactions with external components. Based on the data collected from these observations, RICK produces unit tests with mocks, stubs, and mock-based oracles. We highlight the capabilities of RICK, and how it can be used with real-world Java applications, to generate tests with mocks.

    Comment: Appears in the tool demonstrations track of the IEEE International Conference on Software Testing, Verification and Validation (ICST), 2023
    Schlagwörter Computer Science - Software Engineering
    Erscheinungsdatum 2023-02-09
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel: [Rezension von: Tilman, Rick, The intellectual legacy of Thorstein Veblen]

    Hodgson, Geoffrey Martin / Tilman, Rick

    Journal of economic literature 36 ,1, S. 230-231

    1998  

    Verfasserangabe Geoffrey M. Hodgson
    Schlagwörter 40;49
    Sprache Englisch
    Verlag Assoc
    Erscheinungsort Nashville, Tenn
    Dokumenttyp Artikel
    ZDB-ID 3076-4 ; 2010159-4
    ISSN 0022-0515
    ISSN 0022-0515
    Datenquelle ECONomics Information System

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  3. Buch ; Online: Stable isotope ratios and paleoceanaographic reconstructions from sediment cores 80-548 and 161-978A, supplementary data to: Kh?lifi, Nabil; Sarnthein, Michael; Andersen, Nils; Blanz, Thomas; Frank, Martin; Garbe-Sch?nberg, Carl-Dieter; Haley, Brian A; Stumpf, Rick; Weinelt, Mara (2009): A major and long-term Pliocene intensification of the Mediterranean Outflow, 3.5 - 3.3 Ma ago. Geology, 37(9), 811-814

    Kh?lifi, Nabil / Andersen, Nils / Blanz, Thomas / Frank, Martin / Garbe-Sch?nberg, Carl-Dieter / Haley, Brian A / Sarnthein, Michael / Stumpf, Rick / Weinelt, Mara

    2009  

    Abstract: Largely continuous millennial-scale records of benthic d18O, Mg/Ca-based temperature, and salinity variations in bottom waters were obtained from Deep Sea Drilling Project Site 548 (eastern Atlantic continental margin south of Ireland, 1250 m water depth) ...

    Abstract Largely continuous millennial-scale records of benthic d18O, Mg/Ca-based temperature, and salinity variations in bottom waters were obtained from Deep Sea Drilling Project Site 548 (eastern Atlantic continental margin south of Ireland, 1250 m water depth) for the period between 3.7 and 3.0 million years ago. This site monitored mid-Pliocene changes in Mediterranean Outflow Water (MOW) documented by continuously high Nd values between -10.7 and -9. Site 978 (Alboran Sea, 1930 m water depth) provides a complementary record of bottom water variability in the westernmost Mediterranean Sea, which is taken to represent MOW composition at its source. Both sites are marked by a singular and persistent rise in bottom water salinities by 0.7-1.4 psu and in densities by ~1 kg m-3 from 3.5 to 3.3 Ma, which is matched by an average 3 ?C increase in bottom water temperatures at Site 548. This event suggests the onset of strongly enhanced deep-water convection in the Mediterranean Sea and a related strengthened MOW flow, which implies a major aridification of the Mediterranean source region. In harmony with model suggestions, the enhanced MOW flow has possibly intensified Upper North Atlantic Deep Water formation.
    Sprache Englisch
    Erscheinungsverlauf 2009-9999
    Umfang Online-Ressource
    Verlag PANGAEA - Data Publisher for Earth & Environmental Science
    Erscheinungsort Bremen/Bremerhaven
    Dokumenttyp Buch ; Online
    Anmerkung This dataset is supplement to doi:10.1130/G30058A.1
    DOI 10.1594/PANGAEA.716848
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  4. Artikel ; Online: Does taking BP medicine at night (vs morning) result in fewer cardiovascular events?

    Martin, Robert / Guthmann, Rick

    The Journal of family practice

    2023  Band 72, Heft 9, Seite(n) E11–E13

    Abstract: PROBABLY NOT. In patients who have hypertension, the timing of administration of antihypertensive medications does not appear to impact cardiovascular outcomes (strength of recommendation: B; contradictory randomized controlled trials). ...

    Abstract PROBABLY NOT. In patients who have hypertension, the timing of administration of antihypertensive medications does not appear to impact cardiovascular outcomes (strength of recommendation: B; contradictory randomized controlled trials).
    Mesh-Begriff(e) Humans ; Blood Pressure ; Hypertension/drug therapy ; Antihypertensive Agents/therapeutic use ; Blood Pressure Monitoring, Ambulatory
    Chemische Substanzen Antihypertensive Agents
    Sprache Englisch
    Erscheinungsdatum 2023-11-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 197883-4
    ISSN 1533-7294 ; 0094-3509
    ISSN (online) 1533-7294
    ISSN 0094-3509
    DOI 10.12788/jfp.0697
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Vaccination Beliefs and Attitudes of Lactating People During the SARS-CoV-2 Pandemic.

    Mark, Elyse G / Demirci, Jill R / Megli, Christina / Martin, Judith M / Rick, Anne-Marie

    Journal of human lactation : official journal of International Lactation Consultant Association

    2023  Band 39, Heft 3, Seite(n) 415–425

    Abstract: Background: Pregnant and recently pregnant people have lower vaccination rates against SARS-CoV-2 than the general population, despite increased risk of adverse outcomes from infection. Little is known about vaccine hesitancy in this population.: ... ...

    Abstract Background: Pregnant and recently pregnant people have lower vaccination rates against SARS-CoV-2 than the general population, despite increased risk of adverse outcomes from infection. Little is known about vaccine hesitancy in this population.
    Research aim: To characterize SARS-CoV-2 and other vaccine attitudes of lactating people who accepted the SARS-CoV-2 vaccine, describing their vaccine experiences to further contextualize their beliefs.
    Methods: A prospective cross-sectional online survey design was used. We administered the survey to 100 lactating people in Pennsylvania from April to August 2021, upon enrollment into a longitudinal study investigating SARS-CoV-2 vaccine antibodies in human milk. This survey assessed SARS-CoV-2 vaccine attitudes, vaccine counseling from providers, and vaccine decision making. Associations between vaccination timing and beliefs were analyzed by Pearson chi-square.
    Results: Of 100 respondents, all received ≥ 1 SARS-CoV-2 vaccine before or shortly after enrollment, with 44% (
    Conclusions: Despite high uptake of SARS-CoV-2 vaccine among participants, safety concerns persisted, with many reporting a lack of direct counseling from providers. Future research should investigate how variability in provider counseling affects SARS-CoV-2 vaccine uptake in perinatal populations.
    Mesh-Begriff(e) Infant ; Female ; Pregnancy ; Humans ; Child ; COVID-19 Vaccines ; SARS-CoV-2 ; Cross-Sectional Studies ; Lactation ; Longitudinal Studies ; Pandemics ; Prospective Studies ; COVID-19/prevention & control ; Breast Feeding ; Vaccination
    Chemische Substanzen COVID-19 Vaccines
    Sprache Englisch
    Erscheinungsdatum 2023-04-03
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1138470-0
    ISSN 1552-5732 ; 0890-3344
    ISSN (online) 1552-5732
    ISSN 0890-3344
    DOI 10.1177/08903344231159640
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Categorical Risk Stratification for Neonatal Early Onset Sepsis using Suspected Intraamniotic Infection and the Newborn Exam.

    Rick, Anne-Marie / Copp, Elizabeth / Buckley, Abigail / Yanowitz, Toby / Martin, Judith / Shaikh, Nader / Switzer, Galen / Hooven, Thomas / Beigi, Richard

    Research square

    2023  

    Abstract: Objective: To determine test characteristics of categorical risk stratification for early onset sepsis (EOS) using maternal criteria for suspected intraamniotic infection (IAI) and/or newborn exam and compare them to the EOS calculator.: Study design!# ...

    Abstract Objective: To determine test characteristics of categorical risk stratification for early onset sepsis (EOS) using maternal criteria for suspected intraamniotic infection (IAI) and/or newborn exam and compare them to the EOS calculator.
    Study design: Retrospective 1:3 case-control study of late preterm/term infants with bacterial culture growth obtained <72 hours of life. For categorical approach, infants of mothers with suspected IAI or equivocal/ill appearing were presumed high-risk for EOS and blood culture obtained. For calculator, estimated probability of EOS and care recommendations were recorded from online calculator. Test characteristics were compared with McNemar's test; recommendation for blood culture was considered a "positive" test.
    Result: 52 cases and 172 controls were included. Compared to the calculator, the categorical approach had higher sensitivity 90%(95%CI:79-96%) vs 67% (95%CI:54-79%) but lower specificity 85%(95%CI:78-89%) vs. 92%(95%CI:87-96%). 10% of cases were not identified by either.
    Conclusion: A categorical approach using suspected IAI/newborn exam offers good EOS discrimination and is comparable to the calculator.
    Sprache Englisch
    Erscheinungsdatum 2023-08-01
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.21203/rs.3.rs-2838294/v1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Clinical Features of Group A Streptococcus in Children With Pharyngitis: Carriers versus Acute Infection.

    Rick, Anne-Marie / Zaheer, Haniah A / Martin, Judith M

    The Pediatric infectious disease journal

    2020  Band 39, Heft 6, Seite(n) 483–488

    Abstract: Background: Among children with pharyngitis who test positive for group A Streptococcus (GAS), 10%-25% are GAS carriers. Current laboratory methods cannot distinguish acute infection from colonization.: Methods: We examined 2 separate longitudinal ... ...

    Abstract Background: Among children with pharyngitis who test positive for group A Streptococcus (GAS), 10%-25% are GAS carriers. Current laboratory methods cannot distinguish acute infection from colonization.
    Methods: We examined 2 separate longitudinal studies of children with symptomatic pharyngitis associated with a positive GAS throat culture (illness culture). In cohort 1, children presented with pharyngitis symptoms to a clinician, then had follow-up cultures at regular intervals. In cohort 2, throat cultures were performed at regular intervals and with pharyngitis symptoms. Illness cultures were categorized as acute infection or carrier based on follow-up culture results. In cohort 2, carriers were further categorized as a GAS carrier with a new emm-type or a GAS carrier with a previous emm-type based on typing data from prior culture results. For each cohort, symptoms were compared at the time of illness culture between carriers and those with acute infection.
    Results: Cohort 1 (N = 75 illness cultures): 87% of the children were classified as acutely infected versus 13% carriers. Carriers were more likely to have upper respiratory (URI) symptoms [odds ratio (OR): 5.5; 95% confidence interval (CI): 1.4-22.1], headache (OR: 6.0; 95% CI: 1.2-40.5) or vomiting (OR: 5.5; 95% CI: 1.2-24.5). Cohort 2 (N = 122 illness cultures): 79% were acutely infected and 21% were carriers. Children determined to be carriers with a previous detected emm-type were more likely to have URI symptoms compared with those with acquisition of a new emm-type.
    Conclusions: Children with symptomatic pharyngitis and GAS on throat culture identified as carriers were more likely to present with URI and atypical symptoms than children who were acutely infected.
    Mesh-Begriff(e) Acute Disease/epidemiology ; Adolescent ; Carrier State/epidemiology ; Carrier State/microbiology ; Child ; Child, Preschool ; Female ; Humans ; Longitudinal Studies ; Male ; Pharyngitis/epidemiology ; Pharyngitis/microbiology ; Retrospective Studies ; Streptococcal Infections/epidemiology ; Streptococcal Infections/microbiology ; Streptococcus pyogenes
    Sprache Englisch
    Erscheinungsdatum 2020-01-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002602
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Stress degrades working memory-related frontostriatal circuit function.

    Berridge, Craig W / Devilbiss, David M / Martin, Andrea J / Spencer, Robert C / Jenison, Rick L

    Cerebral cortex (New York, N.Y. : 1991)

    2023  Band 33, Heft 12, Seite(n) 7857–7869

    Abstract: Goal-directed behavior is dependent on neuronal activity in the prefrontal cortex (PFC) and extended frontostriatal circuitry. Stress and stress-related disorders are associated with impaired frontostriatal-dependent cognition. Our understanding of the ... ...

    Abstract Goal-directed behavior is dependent on neuronal activity in the prefrontal cortex (PFC) and extended frontostriatal circuitry. Stress and stress-related disorders are associated with impaired frontostriatal-dependent cognition. Our understanding of the neural mechanisms that underlie stress-related cognitive impairment is limited, with the majority of prior research focused on the PFC. To date, the actions of stress across cognition-related frontostriatal circuitry are unknown. To address this gap, the current studies examined the effects of acute noise-stress on the spiking activity of neurons and local field potential oscillatory activity within the dorsomedial PFC (dmPFC) and dorsomedial striatum (dmSTR) in rats engaged in a test of spatial working memory. Stress robustly suppressed responses of both dmPFC and dmSTR neurons strongly tuned to key task events (delay, reward). Additionally, stress strongly suppressed delay-related, but not reward-related, theta and alpha spectral power within, and synchrony between, the dmPFC and dmSTR. These observations provide the first demonstration that stress disrupts the neural coding and functional connectivity of key task events, particularly delay, within cognition-supporting dorsomedial frontostriatal circuitry. These results suggest that stress-related degradation of neural coding within both the PFC and striatum likely contributes to the cognition-impairing effects of stress.
    Mesh-Begriff(e) Rats ; Animals ; Memory, Short-Term/physiology ; Corpus Striatum/physiology ; Neostriatum ; Prefrontal Cortex/physiology ; Neurons/physiology
    Sprache Englisch
    Erscheinungsdatum 2023-03-18
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1077450-6
    ISSN 1460-2199 ; 1047-3211
    ISSN (online) 1460-2199
    ISSN 1047-3211
    DOI 10.1093/cercor/bhad084
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Weathering of 3-component synthetic food cones: effects on residual amount, release rate, and field capture of 3 pest species of fruit flies (Diptera: Tephritidae).

    Shelly, Todd E / Kurashima, Rick / Mesa Martin, Rodolfo / Fezza, Thomas / Bazelet, Corinna

    Environmental entomology

    2023  Band 52, Heft 3, Seite(n) 408–415

    Abstract: Food-based baits are an important component of trapping networks designed to detect invasive tephritid fruit flies (Diptera: Tephritidae). An aqueous solution of torula yeast plus borax (TYB) is widely used, but synthetic food lures have been developed ... ...

    Abstract Food-based baits are an important component of trapping networks designed to detect invasive tephritid fruit flies (Diptera: Tephritidae). An aqueous solution of torula yeast plus borax (TYB) is widely used, but synthetic food lures have been developed to facilitate field procedures, ensure standard composition, and lengthen the interval of bait attractiveness. Cone-shaped dispensers, containing ammonium acetate, putrescine, and trimethylamine (so-called 3C food cones), are currently being used in some large-scale trapping systems (e.g., Florida). Prior work in Hawaii showed that traps baited with 3C food cones capture similar numbers of Mediterranean fruit flies (medflies), Ceratitis capitata (Wiedemann), as TYB-baited traps after 1-2 wk of weathering but capture fewer medflies thereafter. In addition, 3C food cones attract fewer oriental fruit flies, Bactrocera dorsalis (Hendel), and melon flies, Zeugodacuscucurbitae (Coquillett) than TYB even when the food cones are freshly deployed. The current study describes an additional trapping experiment that expands upon earlier work by (i) presenting 3C food cones either unbagged (as done previously) or in nonporous or breathable bags to possibly reduce volatilization and lengthen bait effectiveness and (ii) measuring the content of the 3 components over time to potentially associate fruit fly captures with the loss of these food cone constituents. Implications of these findings for fruit fly surveillance programs are discussed.
    Mesh-Begriff(e) Animals ; Tephritidae ; Insect Control/methods ; Pheromones/pharmacology ; Ceratitis capitata ; Food ; Drosophila ; Saccharomyces cerevisiae
    Chemische Substanzen Pheromones
    Sprache Englisch
    Erscheinungsdatum 2023-04-24
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 120799-4
    ISSN 1938-2936 ; 0046-2268 ; 0046-225X
    ISSN (online) 1938-2936
    ISSN 0046-2268 ; 0046-225X
    DOI 10.1093/ee/nvad031
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Identification of a CTX-M-255 β-lactamase containing a G239S substitution selectively conferring resistance to penicillin/β-lactamase inhibitor combinations.

    Andreasen, Minna Rud / Rick, Tim / Alexandersen, Nicolai Riff / Hansen, Katrine Hartung / Pedersen, Martin Schou / Warweitzky, Jakob K / Botelho, Carolina Mastella / Häussler, Susanne / Jelsbak, Lotte / Schønning, Kristian

    The Journal of antimicrobial chemotherapy

    2024  Band 79, Heft 4, Seite(n) 810–814

    Abstract: Objectives: An Escherichia coli isolate, WGS1363, showed resistance to piperacillin/tazobactam but susceptibility to cephalosporins and contained a previously unrecognized β-lactamase, CTX-M-255, as the only acquired β-lactamase. CTX-M-255 was identical ...

    Abstract Objectives: An Escherichia coli isolate, WGS1363, showed resistance to piperacillin/tazobactam but susceptibility to cephalosporins and contained a previously unrecognized β-lactamase, CTX-M-255, as the only acquired β-lactamase. CTX-M-255 was identical to CTX-M-27 except for a G239S substitution. Here, we characterize the hydrolytic spectrum of CTX-M-255 and a previously reported β-lactamase, CTX-M-178, also containing a G239S substitution and compare it to their respective parental enzymes, CTX-M-27 and CTX-M-15.
    Methods: All β-lactamase genes were expressed in E. coli TOP10 and MICs to representative β-lactam-antibiotics were determined. Furthermore, blaCTX-M-15,  blaCTX-M-27, blaCTX-M-178 and blaCTX-M-255 with C-terminal His-tag fusions were affinity purified for enzyme kinetic assays determining Michaelis-Menten kinetic parameters against representative β-lactam-antibiotics and IC50s of clavulanate, sulbactam, tazobactam and avibactam.
    Results: TOP10-transformants expressing blaCTX-M-178 and blaCTX-M-255 showed resistance to penicillin/β-lactamase combinations and susceptibility to cephalothin and cefotaxime in contrast to transformants expressing blaCTX-M-15 and blaCTX-M-27. Determination of enzyme kinetic parameters showed that CTX-M-178 and CTX-M-255 both lacked hydrolytic activity against cephalosporins and showed impaired hydrolytic efficiency against penicillin antibiotics compared to their parental enzymes. Both enzymes appeared more active against piperacillin compared to benzylpenicillin and ampicillin. Compared to their parental enzymes, IC50s of β-lactamase-inhibitors were increased more than 1000-fold for CTX-M-178 and CTX-M-255.
    Conclusions: CTX-M-178 and CTX-M-255, both containing a G239S substitution, conferred resistance to piperacillin/tazobactam and may be characterized as inhibitor-resistant CTX-M β-lactamases. Inhibitor resistance was accompanied by loss of activity against cephalosporins and monobactams. These findings add to the necessary knowledge base for predicting antibiotic susceptibility from genotypic data.
    Mesh-Begriff(e) beta-Lactamase Inhibitors/pharmacology ; Anti-Bacterial Agents/pharmacology ; Escherichia coli ; beta-Lactamases/genetics ; Penicillins/pharmacology ; Cephalosporins/pharmacology ; Tazobactam/pharmacology ; Piperacillin/pharmacology ; Monobactams ; Piperacillin, Tazobactam Drug Combination ; Microbial Sensitivity Tests
    Chemische Substanzen beta-Lactamase Inhibitors ; Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6) ; Penicillins ; Cephalosporins ; Tazobactam (SE10G96M8W) ; Piperacillin (X00B0D5O0E) ; Monobactams ; Piperacillin, Tazobactam Drug Combination (157044-21-8)
    Sprache Englisch
    Erscheinungsdatum 2024-02-15
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkae033
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 124: Hefte anzeigen

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