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  1. Book: Environmental health

    Myatt, Theodore A. / Allen, Joseph G.

    indoor exposures, assessments and interventions

    2013  

    Author's details ed. by Theodore A. Myatt and Joseph G. Allen ed
    Language English
    Size XVII, 233 S.
    Publisher Apple Acad. Press
    Publishing place Oakville
    Publishing country Canada
    Document type Book
    HBZ-ID HT017181711
    ISBN 978-1-926895-20-8 ; 1-926895-20-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 5210 order for loan Magazin

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  2. Article ; Online: Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission.

    Allen, Joseph G / Ibrahim, Andrew M

    JAMA

    2021  Volume 325, Issue 20, Page(s) 2112–2113

    Language English
    Publishing date 2021-04-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2021.5053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.88: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Mechanical Regulation of Endocytosis: New Insights and Recent Advances.

    Joseph, Jophin G / Liu, Allen P

    Advanced biosystems

    2020  Volume 4, Issue 8, Page(s) e2000155

    Language English
    Publishing date 2020-07-21
    Publishing country Germany
    Document type Published Erratum
    ISSN 2366-7478
    ISSN 2366-7478
    DOI 10.1002/adbi.202000155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Efficacy and clinical potential of phage therapy in treating methicillin-resistant Staphylococcus aureus (MRSA) infections: A review.

    Fortaleza, Jamil Allen G / Ong, Christian Joseph N / De Jesus, Rener

    European journal of microbiology & immunology

    2024  Volume 14, Issue 1, Page(s) 13–25

    Abstract: Staphylococcus aureus infections have already presented a substantial public health challenge, encompassing different clinical manifestations, ranging from bacteremia to sepsis and multi-organ failures. Among these infections, methicillin-resistant S. ... ...

    Abstract Staphylococcus aureus infections have already presented a substantial public health challenge, encompassing different clinical manifestations, ranging from bacteremia to sepsis and multi-organ failures. Among these infections, methicillin-resistant S. aureus (MRSA) is particularly alarming due to its well-documented resistance to multiple classes of antibiotics, contributing significantly to global mortality rates. Consequently, the urgent need for effective treatment options has prompted a growing interest in exploring phage therapy as a potential non-antibiotic treatment against MRSA infections. Phages represent a class of highly specific bacterial viruses known for their ability to infect certain bacterial strains. This review paper explores the clinical potential of phages as a treatment for MRSA infections due to their low toxicity and auto-dosing capabilities. The paper also discusses the synergistic effect of phage-antibiotic combination (PAC) and the promising results from in vitro and animal model studies, which could lead to extensive human clinical trials. However, clinicians need to establish and adhere to standard protocols governing phage administration and implementation. Prominent clinical trials are needed to develop and advance phage therapy as a non-antibiotic therapy intervention, meeting regulatory guidelines, logistical requirements, and ethical considerations, potentially revolutionizing the treatment of MRSA infections.
    Language English
    Publishing date 2024-02-02
    Publishing country Hungary
    Document type Journal Article ; Review
    ZDB-ID 2652327-9
    ISSN 2062-8633 ; 2062-509X
    ISSN (online) 2062-8633
    ISSN 2062-509X
    DOI 10.1556/1886.2023.00064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Recognizing and controlling airborne transmission of SARS-CoV-2 in indoor environments.

    Allen, Joseph G / Marr, Linsey C

    Indoor air

    2020  Volume 30, Issue 4, Page(s) 557–558

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Severe acute respiratory syndrome-related coronavirus ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.12697
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Bonn / Germany

    Z 7724: Show issues

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  6. Article: Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1).

    Joseph, Thomas T / Bu, Weiming / Haji-Ghassemi, Omid / Chen, Yu Seby / Woll, Kellie / Allen, Paul D / Brannigan, Grace / van Petegem, Filip / Eckenhoff, Roderic G

    bioRxiv : the preprint server for biology

    2024  

    Abstract: As the primary ... ...

    Abstract As the primary Ca
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.10.575040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Mechanical Regulation of Endocytosis: New Insights and Recent Advances.

    Joseph, Jophin G / Liu, Allen P

    Advanced biosystems

    2020  Volume 4, Issue 5, Page(s) e1900278

    Abstract: Endocytosis is a mechanosensitive process. It involves remodeling of the plasma membrane from a flat shape to a budded morphology, often at the sub-micrometer scale. This remodeling process is energy-intensive and is influenced by mechanical factors such ...

    Abstract Endocytosis is a mechanosensitive process. It involves remodeling of the plasma membrane from a flat shape to a budded morphology, often at the sub-micrometer scale. This remodeling process is energy-intensive and is influenced by mechanical factors such as membrane tension, membrane rigidity, and physical properties of cargo and extracellular surroundings. The cellular responses to a variety of mechanical factors by distinct endocytic pathways are important for cells to counteract rapid and extreme disruptions in the mechanohomeostasis of cells. Recent advances in microscopy and mechanical manipulation at the cellular scale have led to new discoveries of mechanoregulation of endocytosis by the aforementioned factors. While factors such as membrane tension and membrane rigidity are generally shown to inhibit endocytosis, other mechanical stimuli have complex relationships with endocytic pathways. At this juncture, it is now possible to utilize experimental techniques to interrogate theoretical predictions on mechanoregulation of endocytosis in cells and even living organisms.
    MeSH term(s) Animals ; Cell Membrane/genetics ; Cell Membrane/metabolism ; Clathrin-Coated Vesicles/genetics ; Clathrin-Coated Vesicles/metabolism ; Endocytosis ; Humans ; Metabolic Networks and Pathways ; Models, Biological
    Language English
    Publishing date 2020-03-24
    Publishing country Germany
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ISSN 2366-7478
    ISSN 2366-7478
    DOI 10.1002/adbi.201900278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Harnessing the power of healthy buildings research to advance health for all.

    Allen, Joseph G / Waring, Michael S

    Journal of exposure science & environmental epidemiology

    2019  Volume 30, Issue 2, Page(s) 217–218

    Language English
    Publishing date 2019-12-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 2218551-3
    ISSN 1559-064X ; 1559-0631
    ISSN (online) 1559-064X
    ISSN 1559-0631
    DOI 10.1038/s41370-019-0195-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7529: Show issues

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  9. Article ; Online: Organic Fluorine as an Indicator of Per- and Polyfluoroalkyl Substances in Dust from Buildings with Healthier versus Conventional Materials.

    Young, Anna S / Pickard, Heidi M / Sunderland, Elsie M / Allen, Joseph G

    Environmental science & technology

    2022  Volume 56, Issue 23, Page(s) 17090–17099

    Abstract: Per- and polyfluoroalkyl substances (PFAS) are a class of thousands of persistent, organic fluorinated chemicals added to materials and products mainly to repel stains and water. PFAS have been associated with many adverse human health effects. We aimed ... ...

    Abstract Per- and polyfluoroalkyl substances (PFAS) are a class of thousands of persistent, organic fluorinated chemicals added to materials and products mainly to repel stains and water. PFAS have been associated with many adverse human health effects. We aimed to determine whether buildings with "healthier" materials─defined here as reportedly free of all PFAS─exhibit lower PFAS in dust. In addition to analyzing targeted PFAS with available commercial standards, we measured extractable organic fluorine (EOF) as a novel proxy that includes both known and unknown types of PFAS. We measured at least 15 targeted PFAS (
    MeSH term(s) Humans ; Dust ; Fluorine ; Fluorocarbons/analysis ; Construction Materials ; Organic Chemicals ; Fluorides
    Chemical Substances Dust ; Fluorine (284SYP0193) ; Fluorocarbons ; Organic Chemicals ; Fluorides (Q80VPU408O)
    Language English
    Publishing date 2022-11-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.2c05198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Risk of recurrence after neoadjuvant chemotherapy and transoral robotic surgery in patients with oropharynx cancer that avoid adjuvant radiation.

    Pershad, Alisha R / Thakkar, Punam G / Goodman, Joseph F / Joshi, Arjun / Steinberg, Seth M / Allen, Clint T / Floudas, Charalampos S

    Cancer medicine

    2024  Volume 13, Issue 7, Page(s) e7146

    Abstract: Background: De-escalation strategies for newly-diagnosed p16-positive oropharyngeal squamous cell carcinoma (p16+ OPSCC), aim to reduce treatment-related morbidity without compromising disease control. One strategy is neoadjuvant cisplatin and docetaxel ...

    Abstract Background: De-escalation strategies for newly-diagnosed p16-positive oropharyngeal squamous cell carcinoma (p16+ OPSCC), aim to reduce treatment-related morbidity without compromising disease control. One strategy is neoadjuvant cisplatin and docetaxel chemotherapy (NAC + S) before transoral robotic surgery, with pathology-based risk-adapted adjuvant treatment.
    Methods: We examined the recurrence-free survival (RFS) for patients who received NAC + S.
    Results: Comparing outcomes in 103 patients between 2008 and 2023, 92% avoided adjuvant treatment and showed significantly higher 2-year recurrence-free survival (RFS) compared to those with adjuvant treatment (95.9% vs. 43.8%, p = 0.0049) CONCLUSION: Our findings suggest that pathology-based risk-adapted omission of adjuvant treatment following NAC + S does not appear to elevate recurrence risk and that NAC may identify patients with favorable tumor biology, yielding a 2-year RFS probability exceeding 95% without adjuvant treatment. Further, the study identifies a patient subset experiencing disease recurrence despite triple modality therapy. Despite limitations, including a retrospective design and modest sample size, the data advocate for controlled NAC + S studies.
    MeSH term(s) Humans ; Neoadjuvant Therapy ; Retrospective Studies ; Robotic Surgical Procedures/adverse effects ; Carcinoma, Squamous Cell/surgery ; Neoplasm Recurrence, Local/prevention & control ; Oropharyngeal Neoplasms/surgery ; Chemotherapy, Adjuvant ; Head and Neck Neoplasms/etiology
    Language English
    Publishing date 2024-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.7146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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