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  1. Article ; Online: New aporphine alkaloids with antitumor activities from the roots of

    Chen, Zhao-Jing / Yang, Han-Gao / Zhu, Wen-Peng / Xue, Chun-Mei / Zhang, Hong-Mei / Peng, Yu-Ting / Li, Da-Hong / Hua, Hui-Ming

    Journal of Asian natural products research

    2024  , Page(s) 1–9

    Abstract: Two new aporphine alkaloids, ... ...

    Abstract Two new aporphine alkaloids, 6a
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077926-4
    ISSN 1477-2213 ; 1028-6020
    ISSN (online) 1477-2213
    ISSN 1028-6020
    DOI 10.1080/10286020.2024.2317826
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  2. Article ; Online: Dynamic network link prediction with node representation learning from graph convolutional networks.

    Mei, Peng / Zhao, Yu Hong

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 538

    Abstract: Dynamic network link prediction is extensively applicable in various scenarios, and it has progressively emerged as a focal point in data mining research. The comprehensive and accurate extraction of node information, as well as a deeper understanding of ...

    Abstract Dynamic network link prediction is extensively applicable in various scenarios, and it has progressively emerged as a focal point in data mining research. The comprehensive and accurate extraction of node information, as well as a deeper understanding of the temporal evolution pattern, are particularly crucial in the investigation of link prediction in dynamic networks. To address this issue, this paper introduces a node representation learning framework based on Graph Convolutional Networks (GCN), referred to as GCN_MA. This framework effectively combines GCN, Recurrent Neural Networks (RNN), and multi-head attention to achieve comprehensive and accurate representations of node embedding vectors. It aggregates network structural features and node features through GCN and incorporates an RNN with multi-head attention mechanisms to capture the temporal evolution patterns of dynamic networks from both global and local perspectives. Additionally, a node representation algorithm based on the node aggregation effect (NRNAE) is proposed, which synthesizes information including node aggregation and temporal evolution to comprehensively represent the structural characteristics of the network. The effectiveness of the proposed method for link prediction is validated through experiments conducted on six distinct datasets. The experimental outcomes demonstrate that the proposed approach yields satisfactory results in comparison to state-of-the-art baseline methods.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50977-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Eu(III)-coordination polymer: inhibitory activity on cervical cancer via inducing ROS mediated apoptosis.

    Hong, Dan / Zhao, Hong-Mei

    Drug development and industrial pharmacy

    2020  Volume 46, Issue 12, Page(s) 1919–1926

    Abstract: Under the hydrothermal reaction condition, we prepared a new 3D Eu(III)-based coordination polymer (CP) [Eu( ... ...

    Abstract Under the hydrothermal reaction condition, we prepared a new 3D Eu(III)-based coordination polymer (CP) [Eu(H
    MeSH term(s) Apoptosis ; Female ; Humans ; Molecular Docking Simulation ; Polymers/chemistry ; Reactive Oxygen Species/chemistry ; Uterine Cervical Neoplasms
    Chemical Substances Polymers ; Reactive Oxygen Species
    Keywords covid19
    Language English
    Publishing date 2020-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 751874-2
    ISSN 1520-5762 ; 0363-9045
    ISSN (online) 1520-5762
    ISSN 0363-9045
    DOI 10.1080/03639045.2020.1826508
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1335: Show issues Location:
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  4. Article: Seasonal dynamics of soil nitrogen mineralization and their influencing factors during shrub anthropogenic introduction in desert steppe.

    Li, Zhi-Li / Wang, Hong-Mei / Zhao, Ya-Nan / Zhou, Yu-Rong

    Ying yong sheng tai xue bao = The journal of applied ecology

    2023  Volume 34, Issue 8, Page(s) 2161–2170

    Abstract: We selected enclosed grassland, grazed grassland and shrublands with different planting years (3, 12, 22 years)/densities (intervals of 2, 6, 40 m) to investigate soil N mineralization dynamics in the growing season (April-October) and its influencing ... ...

    Title translation 荒漠草原灌丛引入过程中土壤氮矿化的季节动态及其影响因子.
    Abstract We selected enclosed grassland, grazed grassland and shrublands with different planting years (3, 12, 22 years)/densities (intervals of 2, 6, 40 m) to investigate soil N mineralization dynamics in the growing season (April-October) and its influencing factors during the process of desert steppe-degradation-shrub introduction. The results showed that soil moisture at 0-200 cm layer was decreased with increases of shrub age and density, and that the variations of soil moisture at 0-10 cm layer coincided with seasonal change. Compared with grazed grassland and enclosed grassland, the positive effect of shrubs on soil carbon, nitrogen and phosphorus contents first increased and then decreased with the increases of age and density. Moreover, soil N mineralization significantly varied across months and sites. Soil NO
    MeSH term(s) Seasons ; Biomass ; Carbon ; Nitrogen ; Soil
    Chemical Substances Carbon (7440-44-0) ; Nitrogen (N762921K75) ; Soil
    Language English
    Publishing date 2023-08-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2881809-X
    ISSN 1001-9332
    ISSN 1001-9332
    DOI 10.13287/j.1001-9332.202308.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Considerations regarding a prediction model of surgical site infection after gastrointestinal surgery.

    Zhao, Shenglin / Zhou, Hong / He, Mei

    International journal of surgery (London, England)

    2024  

    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000001426
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6502: Show issues Location:
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  6. Article: [Advances and Application of Genomics in Chronic Obstructive Pulmonary Disease].

    Su, Lin-Fan / Zhao, Hong-Mei / Xiao, Yi

    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

    2022  Volume 44, Issue 4, Page(s) 668–672

    Abstract: Chronic obstructive pulmonary disease (COPD) is a common and frequently-occurring disease in the department of respiratory medicine,the pathogenesis of which involves both environmental factors and genetic factors.In recent years,with the application of ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) is a common and frequently-occurring disease in the department of respiratory medicine,the pathogenesis of which involves both environmental factors and genetic factors.In recent years,with the application of new methods such as genome-wide association study,researchers have discovered a large number of gene mutations associated with lung function and COPD,providing a new perspective on the pathogenesis of COPD and potential therapeutic targets.This article reviews the research achievements and application progress of genomics in COPD.
    MeSH term(s) Genome-Wide Association Study/methods ; Genomics ; Humans ; Pulmonary Disease, Chronic Obstructive/genetics
    Language Chinese
    Publishing date 2022-09-05
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 604853-5
    ISSN 1000-503X
    ISSN 1000-503X
    DOI 10.3881/j.issn.1000-503X.13784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2554: Show issues Location:
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  7. Article ; Online: Dynamic network link prediction with node representation learning from graph convolutional networks

    Peng Mei / Yu hong Zhao

    Scientific Reports, Vol 14, Iss 1, Pp 1-

    2024  Volume 12

    Abstract: Abstract Dynamic network link prediction is extensively applicable in various scenarios, and it has progressively emerged as a focal point in data mining research. The comprehensive and accurate extraction of node information, as well as a deeper ... ...

    Abstract Abstract Dynamic network link prediction is extensively applicable in various scenarios, and it has progressively emerged as a focal point in data mining research. The comprehensive and accurate extraction of node information, as well as a deeper understanding of the temporal evolution pattern, are particularly crucial in the investigation of link prediction in dynamic networks. To address this issue, this paper introduces a node representation learning framework based on Graph Convolutional Networks (GCN), referred to as GCN_MA. This framework effectively combines GCN, Recurrent Neural Networks (RNN), and multi-head attention to achieve comprehensive and accurate representations of node embedding vectors. It aggregates network structural features and node features through GCN and incorporates an RNN with multi-head attention mechanisms to capture the temporal evolution patterns of dynamic networks from both global and local perspectives. Additionally, a node representation algorithm based on the node aggregation effect (NRNAE) is proposed, which synthesizes information including node aggregation and temporal evolution to comprehensively represent the structural characteristics of the network. The effectiveness of the proposed method for link prediction is validated through experiments conducted on six distinct datasets. The experimental outcomes demonstrate that the proposed approach yields satisfactory results in comparison to state-of-the-art baseline methods.
    Keywords Medicine ; R ; Science ; Q
    Subject code 006
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: 维生素D在克罗恩病中的作用机制及外源性补充作用.

    Xia, Yu / Zhou, Juan / Zhao, Hong-Mei / You, Jie-Yu

    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

    2023  Volume 25, Issue 8, Page(s) 870–876

    Abstract: Vitamin D can not only regulate calcium and phosphorus metabolism, but also exert an immunoregulatory effect. Vitamin D deficiency is common in patients with Crohn's disease (CD). Studies have shown that vitamin D is associated with CD and other ... ...

    Title translation Mechanism of action and exogenous supplementation of vitamin D in Crohn's disease.
    Abstract Vitamin D can not only regulate calcium and phosphorus metabolism, but also exert an immunoregulatory effect. Vitamin D deficiency is common in patients with Crohn's disease (CD). Studies have shown that vitamin D is associated with CD and other autoimmune diseases and can improve the condition of patients with CD and promote their recovery by regulating intestinal immunity, repairing the intestinal mucosal barrier, inhibiting intestinal fibrosis, enhancing the response to infliximab, and regulating intestinal microbiota. Exogenous vitamin D supplementation can induce disease remission while increasing the serum level of vitamin D. However, only a few randomized, double-blind, and placebo-controlled trials have investigated the therapeutic effect of vitamin D in CD, and the optimal form of vitamin D supplementation, the specific dosage of vitamin D supplementation, and the optimal serum maintenance concentration of vitamin D remain to be clarified. This article mainly discusses the mechanism of action of vitamin D in CD and the beneficial effect of exogenous vitamin D supplementation on CD.
    MeSH term(s) Humans ; Calcium, Dietary ; Crohn Disease/drug therapy ; Dietary Supplements ; Infliximab ; Vitamin D/pharmacology ; Vitamin D/therapeutic use
    Chemical Substances Calcium, Dietary ; Infliximab (B72HH48FLU) ; Vitamin D (1406-16-2)
    Language Chinese
    Publishing date 2023-09-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1008-8830
    ISSN 1008-8830
    DOI 10.7499/j.issn.1008-8830.2212064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: 2-Furoic acid associated with the infection of nematodes by

    Lei, Hong-Mei / Wang, Jun-Tao / Hu, Qian-Yi / Li, Chun-Qiang / Mo, Ming-He / Zhang, Ke-Qin / Li, Guo-Hong / Zhao, Pei-Ji

    Microbiology spectrum

    2023  , Page(s) e0189623

    Abstract: Dactylellina ... ...

    Abstract Dactylellina haptotyla
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01896-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Spatial-temporal distribution and pedestrian exposure assessment of size-fractionated particles on crosswalk of urban intersection.

    He, Hong-di / Wang, Zi-Ye / Zhao, Hong-Mei / Pan, Wei / Lu, Wei-Zhen

    Environmental science and pollution research international

    2023  Volume 30, Issue 35, Page(s) 83917–83928

    Abstract: Vehicles tend to produce more pollutants especially particles at an urban intersection than other segments. Meanwhile, pedestrians at an intersection are inevitably exposed to high particle level and suffered from the health problem. Especially, some ... ...

    Abstract Vehicles tend to produce more pollutants especially particles at an urban intersection than other segments. Meanwhile, pedestrians at an intersection are inevitably exposed to high particle level and suffered from the health problem. Especially, some particles can deposit in different thoracic areas of the respiratory system and cause serious health problems. Hence, in this paper, the particles from 0.3 to 10 μm in 16 channels were measured to compare the spatio-temporal characteristics of them on the crosswalk and the roadside. Based on the roadside of fixed measurements, submicron particles (< 1 μm) are discovered to have a high relation with traffic signal and exhibit a bimodal distribution pattern in the green phase. On the crosswalk of mobile measurements, submicron particles present decreasing trend along the crosswalk while crossing. Additionally, mobile measurements were conducted across six time intervals that correspond to different pedestrian's journey when passing the crosswalk. The results showed that all size particles in the first three journeys present high concentrations than that in other journeys. Furthermore, pedestrian exposure to all 16 channel particles was assessed. The total and regional deposition fractions of these particles in different sizes and age groups are determined. What ought to be paid attention to is that these real-world measurement results contribute to advancing the understanding of pedestrian exposure to size-fractionated particles on crosswalk and assisting the pedestrian to make better informed choice so as to limit particle exposure in these pollution hotspots.
    MeSH term(s) Humans ; Pedestrians ; Air Pollutants/analysis ; Environmental Pollution ; Environmental Pollutants ; Accidents, Traffic
    Chemical Substances Air Pollutants ; Environmental Pollutants
    Language English
    Publishing date 2023-06-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28150-3
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