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  1. Article ; Online: Recurrence of coronavirus disease 2019 (COVID-19), future paths and challenges.

    Andraus, Gabriel Savogin / Dias, Viviane Maria de Carvalho Hessel / Baena, Cristina Pellegrino

    Infection control and hospital epidemiology

    2021  Volume 43, Issue 9, Page(s) 1288–1290

    MeSH term(s) COVID-19 ; Humans ; Public Health ; SARS-CoV-2
    Language English
    Publishing date 2021-05-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2021.226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Blue-Poli (BP): an accessible and rapid method for detecting colistin resistance in Enterobacterales.

    Pillonetto, Marcelo / Kulek, Débora Nicole / Lemke, Angela Guzzo / Andraus, Gabriel Savogin / Becker, Guilherme Nardi

    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

    2022  Volume 53, Issue 4, Page(s) 2195–2197

    MeSH term(s) Colistin/pharmacology ; Microbial Sensitivity Tests ; Drug Resistance, Bacterial ; Anti-Bacterial Agents/pharmacology
    Chemical Substances Colistin (Z67X93HJG1) ; Anti-Bacterial Agents
    Language English
    Publishing date 2022-10-29
    Publishing country Brazil
    Document type Letter
    ZDB-ID 2017175-4
    ISSN 1678-4405 ; 1517-8382
    ISSN (online) 1678-4405
    ISSN 1517-8382
    DOI 10.1007/s42770-022-00862-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Associations between Lifestyle and Sociodemographic Factors in Medical Students: A Cross Sectional Study.

    Andraus, Gabriel Savogin / Vieira, Fernanda Myskovski / Candido, Gabriel de Mello / Patino, Gabrielle Previdi / Bernardelli, Rafaella Stradiotto / de Palma, Homero Luís Aquino

    Journal of lifestyle medicine

    2022  Volume 13, Issue 1, Page(s) 73–82

    Abstract: Background: Identifying lifestyle characteristics in higher education can lead to effective interventions that benefit both individuals and communities.: Methods: This cross-sectional survey-based study was conducted on medical students of a private ... ...

    Abstract Background: Identifying lifestyle characteristics in higher education can lead to effective interventions that benefit both individuals and communities.
    Methods: This cross-sectional survey-based study was conducted on medical students of a private university using the Fantastic Lifestyle Questionnaire (FLQ) to assess healthy lifestyles, as well as a custom sociodemographic questionnaire. Additionally, correlations among sociodemographic factors and alcohol intake, activity, tobacco and toxins, family and friends, insight, nutrition, type of behavior, career, sleep, seatbelt, stress, and safe sex domains were assessed.
    Results: This study assessed 188 lifestyle profiles, of which 148 have complete data for evaluating the total FLQ score. The majority of evaluated lifestyles were characterized as "good (42.5%)" and "very good (35.8%)", and correlations were identified between the total FLQ score and between the preclinical and later course phases, the 18-20 years and older age brackets, and any romantic relationship and being single. Additional associations were observed for the other domains with other sociodemographic factors.
    Conclusion: Medical students frequently present with a lifestyle that may be improved through various targeted interventions.
    Language English
    Publishing date 2022-02-10
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3021714-3
    ISSN 2288-1557 ; 2234-8549
    ISSN (online) 2288-1557
    ISSN 2234-8549
    DOI 10.15280/jlm.2023.13.1.73
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Antithrombotic regimens for the prevention of major adverse cardiac events in chronic coronary syndrome: A systematic review and network meta-analysis.

    Marques, Gustavo Lenci / Albuquerque, Arthur Mendonça / Romaniello, Gabriela / Bozzi, Fernanda Proença Lepca / da Cunha, Gustavo Pereira / Andraus, Gabriel Savogin / Hastreiter, Gabriel / Maniesi, Barbara / Baena, Cristina / Guedes, Murilo

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1040936

    Abstract: Backgroud: Antithrombotic therapy is the cornerstone of chronic coronary syndrome (CCS) management. However, the best treatment option that optimally balances bleeding risk and efficacy remains undefined. Our objective was to evaluate the effectiveness ... ...

    Abstract Backgroud: Antithrombotic therapy is the cornerstone of chronic coronary syndrome (CCS) management. However, the best treatment option that optimally balances bleeding risk and efficacy remains undefined. Our objective was to evaluate the effectiveness and safety of antithrombotic options and identify the optimal treatment option for patients with CCS.
    Methods: We used the MEDLINE, CENTRAL and Embase databases to search for randomized controlled trials with follow-up periods longer than 12 months that compared aspirin (ASA) monotherapy with other antithrombotic therapies in patients with CCS. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used. Extracted data [hazard ratios (HR)] were pooled using Bayesian fixed-effect models, allowing the estimation of credible intervals (CrI) and posterior probabilities of benefit, harm, and practical equivalence. Confidence in the results was assessed with the Confidence In Network Meta-Analysis (CINeMA) tool. The primary efficacy and safety outcomes were major adverse cardiovascular events (MACE) and primary bleeding, respectively. Secondary outcomes were acute myocardial infarction, ischemic stroke, all-cause, and cardiovascular-specific mortality.
    Results: Five trials with a total of 80,605 patients were included. Mean patient age ranged from 61 to 69 years, while 20.3% to 31.4% were women. The reference treatment was ASA monotherapy. ASA + prasugrel 10 mg and clopidogrel 75 mg monotherapy presented the greatest benefit for MACE [HR 0.52 (95% CrI, 0.39-0.71); and 0.68 (95% CrI, 0.54-0.88)]. There was a probability of 98.8% that ASA + ticagrelor was practically equivalent to ASA monotherapy. Regarding the primary bleeding outcome, clopidogrel 75 mg monotherapy performed best [HR 0.64 (0.42, 0.99)]. There was a probability of 97.4% that ASA + Prasugrel 10 mg increases bleeding (HR > 1.0). Secondary outcome results followed a similar treatment ranking pattern as in primary outcomes. Overall, CINeMA confidence ratings were judged as either low or very low.
    Conclusions: These results revealed that clopidogrel monotherapy might provide the best risk-benefit balance in treating CCS. However, low CINeMA confidence ratings may preclude more forceful conclusions. Our analysis suggests that current guidelines recommending ASA as first-line therapy for CCS management need to be revised to include additional pharmacological options.
    Language English
    Publishing date 2023-04-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1040936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Experience of Implementing a National Antimicrobial Resistance Surveillance System in Brazil.

    Pillonetto, Marcelo / Jordão, Regiane Tigulini de Souza / Andraus, Gabriel Savogin / Bergamo, Ricardo / Rocha, Fabiano Barreto / Onishi, Mayara Caroline / de Almeida, Bernardo Montesanti Machado / Nogueira, Keite da Silva / Dal Lin, Amanda / Dias, Viviane Maria de Carvalho Hessel / de Abreu, André Luiz

    Frontiers in public health

    2021  Volume 8, Page(s) 575536

    Abstract: Antimicrobial resistance (AMR) is a major public health threat of global proportions, which has the potential to lead to approximately ten million deaths per year by 2050. Pressured by this wicked problem, in 2014, the World Health Organization launched ... ...

    Abstract Antimicrobial resistance (AMR) is a major public health threat of global proportions, which has the potential to lead to approximately ten million deaths per year by 2050. Pressured by this wicked problem, in 2014, the World Health Organization launched a call for member states to share AMR data through the implementation of the Global Antimicrobial Resistance Surveillance System (GLASS), to appropriately scale and monitor the general situation world-widely. In 2017, Brazil joined GLASS and, in 2018, started its own national antimicrobial surveillance program (BR-GLASS) to understand the impact of resistance in the country. We compiled data obtained from the complete routine of three hospitals' microbiology labs during the year of 2018. This pilot data sums up to 200,874 antimicrobial susceptibility test results from 11,347 isolates. It represents 119 different microorganisms recovered from 44 distinct types of clinical samples. Specimens came from patients originating from 301 Brazilian cities, with 4,950 of these isolates from presumed Healthcare-Associated Infections (HAIs) and the other 6,397 community-acquired cases. The female population offered 58% of the collected samples, while the other 42% were of male origin. The urinary tract was the most common topography (6,372/11,347 isolates), followed by blood samples (2,072/11,347). Gram-negative predominated the bacterial isolates:
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents ; Brazil/epidemiology ; Drug Resistance, Bacterial ; Female ; Humans ; Male ; Pilot Projects
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2021-01-14
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2020.575536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Experience of Implementing a National Antimicrobial Resistance Surveillance System in Brazil

    Marcelo Pillonetto / Regiane Tigulini de Souza Jordão / Gabriel Savogin Andraus / Ricardo Bergamo / Fabiano Barreto Rocha / Mayara Caroline Onishi / Bernardo Montesanti Machado de Almeida / Keite da Silva Nogueira / Amanda Dal Lin / Viviane Maria de Carvalho Hessel Dias / André Luiz de Abreu

    Frontiers in Public Health, Vol

    2021  Volume 8

    Abstract: Antimicrobial resistance (AMR) is a major public health threat of global proportions, which has the potential to lead to approximately ten million deaths per year by 2050. Pressured by this wicked problem, in 2014, the World Health Organization launched ... ...

    Abstract Antimicrobial resistance (AMR) is a major public health threat of global proportions, which has the potential to lead to approximately ten million deaths per year by 2050. Pressured by this wicked problem, in 2014, the World Health Organization launched a call for member states to share AMR data through the implementation of the Global Antimicrobial Resistance Surveillance System (GLASS), to appropriately scale and monitor the general situation world-widely. In 2017, Brazil joined GLASS and, in 2018, started its own national antimicrobial surveillance program (BR-GLASS) to understand the impact of resistance in the country. We compiled data obtained from the complete routine of three hospitals' microbiology labs during the year of 2018. This pilot data sums up to 200,874 antimicrobial susceptibility test results from 11,347 isolates. It represents 119 different microorganisms recovered from 44 distinct types of clinical samples. Specimens came from patients originating from 301 Brazilian cities, with 4,950 of these isolates from presumed Healthcare-Associated Infections (HAIs) and the other 6,397 community-acquired cases. The female population offered 58% of the collected samples, while the other 42% were of male origin. The urinary tract was the most common topography (6,372/11,347 isolates), followed by blood samples (2,072/11,347). Gram-negative predominated the bacterial isolates: Escherichia coli was the most prevalent in general, representing 4,030 isolates (89.0% of these from the urinary tract). Coagulase-negative Staphylococci were the most prevalent bacteria in blood samples. Besides these two species, the ESKAPE group have consolidated their prevalence. Regarding drug susceptibility results, 141,648 (70.5%) were susceptible, 9,950 (4.9%) intermediate, and 49,276 (24.5%) resistant. Acinetobacter baumannii was the most worrisome microorganism, with 65.3% of the overall antimicrobial susceptibility tests showing resistance, followed by ESBL-producing Klebsiella pneumoniae, with a global resistance rate ...
    Keywords surveillance ; antimicrobial resistance ; multiresistant bacteria ; antimicrobial susceptibility tests ; public health ; GLASS - Global Antimicrobial Resistance Surveillance System ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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