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  1. Article ; Online: Technological imbalance: seeking a small-caliber duodenoscope.

    Lin, Tom K / Barth, Bradley / Fishman, Douglas S / Fox, Victor L / Giefer, Matthew J / Gugig, Roberto / Kramer, Robert E / Liu, Quin Y / Mamula, Petar / McOmber, Mark E / Vitale, David S / Wilsey, Michael J / Troendle, David M

    Gastrointestinal endoscopy

    2022  Volume 96, Issue 6, Page(s) 1055–1057

    MeSH term(s) Humans ; Duodenoscopes
    Language English
    Publishing date 2022-08-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2022.08.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of timing, sex, and age on site-specific gastrointestinal permeability testing in children and adults.

    McOmber, Mark E / Ou, Ching-Nan / Shulman, Robert J

    Journal of pediatric gastroenterology and nutrition

    2010  Volume 50, Issue 3, Page(s) 269–275

    Abstract: Objectives: Measurement of gastrointestinal (GI) permeability is commonly used in research and often used clinically. Despite its utility, little is known about sugar excretion timeframes or the potential effects of age and sex on GI permeability ... ...

    Abstract Objectives: Measurement of gastrointestinal (GI) permeability is commonly used in research and often used clinically. Despite its utility, little is known about sugar excretion timeframes or the potential effects of age and sex on GI permeability testing. We seek to determine the timeframes of sugar excretion and the potential effects of age and sex on urinary recovery of the sugars.
    Subjects and methods: Healthy adults (n = 17) and children (n = 15) fasted 4 hours after the evening meal and then ingested a solution of sucrose, lactulose, mannitol, and sucralose. Urine was collected at 30, 60, and 90 minutes after ingestion and then each time the subjects voided during the next 24 hours. Each urine void was collected separately.
    Results: Median age for the adults was 47.5 years (range 21-57 years) and for children 10 years (range 5-17 years). There were no differences between children and adults in mean percent dose of sugar recovered. The time of peak urinary recovery of the sugars was generally similar between children and adults. Sucrose urinary recovery declined with age (P = 0.008; r2 = 0.19) unrelated to sex. Lactulose and sucralose urinary recovery declined with age in females (P = 0.05, r2 = 0.24 and P = 0.011, r2 = 0.41; respectively) but not in males.
    Conclusions: Overall, sugar urinary recovery is comparable in children and adults. Specific sugar urinary recovery may change as a function of age and/or sex. These results need to be taken into account when planning and interpreting gastrointestinal permeability studies.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Biomedical Research/methods ; Cell Membrane Permeability ; Child ; Child, Preschool ; Dietary Sucrose/pharmacokinetics ; Dietary Sucrose/urine ; Female ; Humans ; Intestinal Absorption ; Intestinal Mucosa/metabolism ; Lactulose/pharmacokinetics ; Lactulose/urine ; Male ; Middle Aged ; Sex Factors ; Sucrose/analogs & derivatives ; Sucrose/pharmacokinetics ; Sucrose/urine ; Time Factors ; Young Adult
    Chemical Substances Dietary Sucrose ; Lactulose (4618-18-2) ; Sucrose (57-50-1) ; trichlorosucrose (96K6UQ3ZD4)
    Language English
    Publishing date 2010-01-08
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0b013e3181aa3aa9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Recurrent abdominal pain and irritable bowel syndrome in children.

    McOmber, Mark E / Shulman, Robert J

    Current opinion in pediatrics

    2007  Volume 19, Issue 5, Page(s) 581–585

    Abstract: Purpose of review: Recurrent abdominal pain continues to be one of the most ubiquitous conditions faced by the healthcare team, and has a significant emotional and economic impact. We have moved from considering it a psychological condition to ... ...

    Abstract Purpose of review: Recurrent abdominal pain continues to be one of the most ubiquitous conditions faced by the healthcare team, and has a significant emotional and economic impact. We have moved from considering it a psychological condition to recognizing the physiological and environmental contributions, and considering the condition in the framework of a biopsychosocial model where biology, psychology and social environment interact. Here, we review current studies addressing etiologies, diagnostic techniques and treatment options for recurrent abdominal pain in children.
    Recent findings: Studies continue to highlight the role of visceral hypersensitivity in recurrent abdominal pain. The psychological state of the child and the parent (most often the mother) in terms of their anxiety, somatization and coping skills can, however, modulate the expression of symptoms. Diagnosis still is made by history and physical examination. Newer treatment options include relaxation and distraction therapies as well as medications. The role of probiotics in children remains to be defined.
    Summary: The approach to the child with recurrent abdominal pain must include the recognition of the physiological contributions, and this information must be relayed to the child and parents. Acknowledgement also must be paid to the role of psychological state in the parent as well as in the child in modulating the severity of symptoms.
    MeSH term(s) Abdominal Pain/diagnosis ; Abdominal Pain/psychology ; Abdominal Pain/therapy ; Child ; Humans ; Irritable Bowel Syndrome/diagnosis ; Irritable Bowel Syndrome/psychology ; Irritable Bowel Syndrome/therapy ; Mothers/psychology ; Recurrence
    Language English
    Publishing date 2007-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 1049374-8
    ISSN 1531-698X ; 1040-8703
    ISSN (online) 1531-698X
    ISSN 1040-8703
    DOI 10.1097/MOP.0b013e3282bf6ddc
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Management of ingested foreign bodies in children: a clinical report of the NASPGHAN Endoscopy Committee.

    Kramer, Robert E / Lerner, Diana G / Lin, Tom / Manfredi, Michael / Shah, Manoj / Stephen, Thomas C / Gibbons, Troy E / Pall, Harpreet / Sahn, Ben / McOmber, Mark / Zacur, George / Friedlander, Joel / Quiros, Antonio J / Fishman, Douglas S / Mamula, Petar

    Journal of pediatric gastroenterology and nutrition

    2015  Volume 60, Issue 4, Page(s) 562–574

    Abstract: Foreign body ingestions in children are some of the most challenging clinical scenarios facing pediatric gastroenterologists. Determining the indications and timing for intervention requires assessment of patient size, type of object ingested, location, ... ...

    Abstract Foreign body ingestions in children are some of the most challenging clinical scenarios facing pediatric gastroenterologists. Determining the indications and timing for intervention requires assessment of patient size, type of object ingested, location, clinical symptoms, time since ingestion, and myriad other factors. Often the easiest and least anxiety-producing decision is the one to proceed to endoscopic removal, instead of observation alone. Because of variability in pediatric patient size, there are less firm guidelines available to determine which type of object will safely pass, as opposed to the clearer guidelines in the adult population. In addition, the imprecise nature of the histories often leaves the clinician to question the timing and nature of the ingestion. Furthermore, changes in the types of ingestions encountered, specifically button batteries and high-powered magnet ingestions, create an even greater potential for severe morbidity and mortality among children. As a result, clinical guidelines regarding management of these ingestions in children remain varied and sporadic, with little in the way of prospective data to guide their development. An expert panel of pediatric endoscopists was convened and produced the present article that outlines practical clinical approaches to the pediatric patient with a variety of foreign body ingestions. This guideline is intended as an educational tool that may help inform pediatric endoscopists in managing foreign body ingestions in children. Medical decision making, however, remains a complex process requiring integration of clinical data beyond the scope of these guidelines. These guidelines should therefore not be considered to be a rule or to be establishing a legal standard of care. Caregivers may well choose a course of action outside of those represented in these guidelines because of specific patient circumstances. Furthermore, additional clinical studies may be necessary to clarify aspects based on expert opinion instead of published data. Thus, these guidelines may be revised as needed to account for new data, changes in clinical practice, or availability of new technology.
    MeSH term(s) Child ; Digestive System ; Eating ; Endoscopy ; Foreign Bodies/therapy ; Gastrointestinal Diseases/therapy ; Humans ; Pediatrics
    Language English
    Publishing date 2015-04
    Publishing country United States
    Document type Journal Article ; Practice Guideline ; Research Support, Non-U.S. Gov't
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000000729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bowel preparation for pediatric colonoscopy: report of the NASPGHAN endoscopy and procedures committee.

    Pall, Harpreet / Zacur, George M / Kramer, Robert E / Lirio, Richard A / Manfredi, Michael / Shah, Manoj / Stephen, Thomas C / Tucker, Neil / Gibbons, Troy E / Sahn, Benjamin / McOmber, Mark / Friedlander, Joel / Quiros, J A / Fishman, Douglas S / Mamula, Petar

    Journal of pediatric gastroenterology and nutrition

    2014  Volume 59, Issue 3, Page(s) 409–416

    Abstract: Pediatric bowel preparation protocols used before colonoscopy vary greatly, with no identified standard practice. The present clinical report reviews the evidence for several bowel preparations in children and reports on their use among North American ... ...

    Abstract Pediatric bowel preparation protocols used before colonoscopy vary greatly, with no identified standard practice. The present clinical report reviews the evidence for several bowel preparations in children and reports on their use among North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition members. Publications in the pediatric literature for bowel preparation regimens are described, including mechanisms of action, efficacy and ease of use, and pediatric studies. A survey distributed to pediatric gastroenterology programs across the country reviews present national practice, and cleanout recommendations are provided. Finally, further areas for research are identified.
    MeSH term(s) Adolescent ; Cathartics/administration & dosage ; Cathartics/adverse effects ; Child ; Child, Preschool ; Colonoscopy/methods ; Gastroenterology/methods ; Humans ; Laxatives/administration & dosage ; Laxatives/adverse effects ; Pediatrics/methods ; Practice Patterns, Physicians' ; Preoperative Care/methods
    Chemical Substances Cathartics ; Laxatives
    Language English
    Publishing date 2014-06-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000000447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: NASPGHAN Capsule Endoscopy Clinical Report.

    Friedlander, Joel A / Liu, Quin Y / Sahn, Benjamin / Kooros, Koorosh / Walsh, Catharine M / Kramer, Robert E / Lightdale, Jenifer R / Khlevner, Julie / McOmber, Mark / Kurowski, Jacob / Giefer, Matthew J / Pall, Harpreet / Troendle, David M / Utterson, Elizabeth C / Brill, Herbert / Zacur, George M / Lirio, Richard A / Lerner, Diana G / Reynolds, Carrie /
    Gibbons, Troy E / Wilsey, Michael / Liacouras, Chris A / Fishman, Douglas S

    Journal of pediatric gastroenterology and nutrition

    2016  Volume 64, Issue 3, Page(s) 485–494

    Abstract: Wireless capsule endoscopy (CE) was introduced in 2000 as a less invasive method to visualize the distal small bowel in adults. Because this technology has advanced it has been adapted for use in pediatric gastroenterology. Several studies have described ...

    Abstract Wireless capsule endoscopy (CE) was introduced in 2000 as a less invasive method to visualize the distal small bowel in adults. Because this technology has advanced it has been adapted for use in pediatric gastroenterology. Several studies have described its clinical use, utility, and various training methods but pediatric literature regarding CE is limited. This clinical report developed by the Endoscopic and Procedures Committee of the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition outlines the current literature, and describes the recommended current role, use, training, and future areas of research for CE in pediatrics.
    MeSH term(s) Capsule Endoscopy/adverse effects ; Capsule Endoscopy/education ; Capsule Endoscopy/methods ; Child ; Contraindications, Procedure ; Gastroenterology/education ; Gastrointestinal Diseases/diagnostic imaging ; Gastrointestinal Diseases/therapy ; Humans ; Informed Consent ; North America ; Pediatrics/education ; Treatment Refusal
    Keywords covid19
    Language English
    Publishing date 2016-09-16
    Publishing country United States
    Document type Journal Article ; Practice Guideline
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000001413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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