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Article ; Online: A simple method to rapidly assess the tibial tuberosity-trochlear groove distance using computed tomography.

Kneafsey, Simone L / Russell, Shane P / Power, Fiachra R / Heffernan, Eric J / Hurson, Conor

2023 Volume 192, Issue 6, Page(s) 2839–2843

Abstract: Background: The tibial tuberosity-trochlear groove (TTTG) distance is used to assess patellofemoral instability (PFI) and the likelihood of the development of patellofemoral disorders. The current gold standard in the assessment of the TTTG is computed ... ...

Abstract	Background: The tibial tuberosity-trochlear groove (TTTG) distance is used to assess patellofemoral instability (PFI) and the likelihood of the development of patellofemoral disorders. The current gold standard in the assessment of the TTTG is computed tomography (CT) or magnetic resonance imaging (MRI). The current image software used for viewing these CT images does not allow for easy assessment of the TTTG. Aims: This study presents a simple method to measure the TTTG on any image software, utilizing easily available and affordable stationary. Methods: Four consecutive patients with no known knee pathologies were selected from recent studies at our institution. Their TTTGs were measured using this study's method and validated using the standard, freely available image analysis software Fiji. Pre-defined anatomical landmarks were located and marked using adhesive pieces of paper. The TTTG was defined as the distance between parallel lines through the apex of the tibial tuberosity and trough of the trochlear groove, where each of these lines is perpendicular to the Dorsal Condylar Line. Results: The TTTG measured using this study's method was found to be in agreement with the measurements made using Fiji software. Conclusions: This study demonstrates that the TTTG can be simply and quickly assessed using readily available and affordable stationery, without the need for expensive or complex secondary analysis software. This could allow for the assessment of PFI in the outpatient clinic whilst the patient is present, offering valuable assistance to the orthopaedic surgeon in clinical decision making.
MeSH term(s)	Humans ; Tibia/diagnostic imaging ; Tibia/pathology ; Knee Joint/diagnostic imaging ; Knee Joint/pathology ; Tomography, X-Ray Computed/methods ; Magnetic Resonance Imaging/methods ; Joint Instability/diagnostic imaging
Language	English
Publishing date	2023-02-14
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-023-03302-z
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Article ; Online: Assessing the Impact of the Pediatric Orthopaedic Society of North America (POSNA) Visiting Scholar Program.

Heffernan, Michael J / Song, Bryant / Bovid, Karen M / Leonardi, Claudia / Fornari, Eric D

Journal of pediatric orthopedics

2021 Volume 41, Issue 3, Page(s) 197–201

Abstract: Background: The primary objective of the Pediatric Orthopaedic Society of North America (POSNA)-Children's Orthopaedics in Underserved Regions (COUR) Visiting Scholar Program is to engage emerging leaders from low-income and middle-income countries ( ... ...

Abstract	Background: The primary objective of the Pediatric Orthopaedic Society of North America (POSNA)-Children's Orthopaedics in Underserved Regions (COUR) Visiting Scholar Program is to engage emerging leaders from low-income and middle-income countries (LMICs) in POSNA educational offerings. This study aims to outline the educational and leadership activities pursued by the alumni of the POSNA-COUR Visiting Scholars Program. We hypothesized that there may be a discrepancy between visiting scholar interest level and actual participation in key follow-up educational and leadership activities. Methods: A 32-question online survey developed by the POSNA-COUR committee was electronically delivered to the POSNA-COUR visiting scholarship recipients from 2007 to 2019. The survey inquired about scholars' educational background, clinical practice, and academic interests. Respondents also reported educational, research, and leadership activities that occurred following program participation. Results: Fifty-seven percent (44/77) of the previous scholars participated in the survey. Sixty-eight percent reported that >75% of their practice was comprised of pediatric patients. The COUR scholarship afforded 15 scholars the opportunity to attend their first educational conference in North America. The majority (86%) of respondents consulted POSNA members on care-related issues, 52% organized a POSNA member's visit to their country, and 13% have become members of POSNA. Scholars shared their knowledge with colleagues through lectures (73%), demonstration of surgical skills (63%), mentorship (59%), hosting local courses (43%), and research (14%). There was a significant discrepancy between interest and actual participation in research (98% vs. 16%, P<0.0001), hosting a regional course (98% vs. 43%, P<0.0001), and becoming a member of POSNA (96% vs. 13%, P<0.0001). Conclusions: The POSNA-COUR Visiting Scholar Program is effective at providing beneficial educational opportunities to orthopaedic surgeons from LMICs. There is, however, a significant discrepancy between reported scholar interest and actual engagement in leadership endeavors including: research, organization of regional courses, and POSNA membership. The impact of the POSNA-COUR visiting scholar program can be enhanced through collaboration with scholarship alumni in these key areas. Level of evidence: Level IV-case series.
MeSH term(s)	Adult ; Fellowships and Scholarships ; Humans ; Medical Missions ; Middle Aged ; North America ; Orthopedic Surgeons/education ; Orthopedic Surgeons/statistics & numerical data ; Orthopedics/education ; Pediatrics/education ; Societies, Medical ; Surveys and Questionnaires
Language	English
Publishing date	2021-07-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	604642-3
ISSN	1539-2570 ; 0271-6798
ISSN (online)	1539-2570
ISSN	0271-6798
DOI	10.1097/BPO.0000000000001729
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Article ; Online: Radiology Resident Education: In Defense of the Socratic Method.

Redmond, Ciaran E / Healy, Gerard M / Clifford, Simon / Heffernan, Eric J

Academic radiology

2017 Volume 24, Issue 10, Page(s) 1327

MeSH term(s)	Internship and Residency ; Physicians ; Radiography ; Radiology/education
Language	English
Publishing date	2017-06-19
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	1355509-1
ISSN	1878-4046 ; 1076-6332
ISSN (online)	1878-4046
ISSN	1076-6332
DOI	10.1016/j.acra.2017.04.015
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Article: High bone turnover and hyperparathyroidism after surgery for tumor-induced osteomalacia: A case series.

Kilbane, Mark T / Crowley, Rachel / Heffernan, Eric / D'Arcy, Clare / O'Toole, Gary / Twomey, Patrick J / McKenna, Malachi J

Bone reports

2021 Volume 15, Page(s) 101142

Abstract: Tumor-induced osteomalacia (TIO) is an ultrarare disorder that is caused by renal phosphate wasting due to uncontrolled tumoral production of fibroblast growth factor 23 (FGF23) from phosphaturic mesenchymal tumors. Surgical removal of the tumor is ... ...

Abstract	Tumor-induced osteomalacia (TIO) is an ultrarare disorder that is caused by renal phosphate wasting due to uncontrolled tumoral production of fibroblast growth factor 23 (FGF23) from phosphaturic mesenchymal tumors. Surgical removal of the tumor is curative. There is limited information on the biochemical changes in mineral metabolism and bone remodeling activity after surgery, but it is reported that surgery is followed by a hungry bone syndrome (HBS) with hypocalcemia and secondary hyperparathyroidism. We report the biochemical response to surgery in two patients, who presented with severe TIO, as manifested by proximal myopathy, multiple stress fractures, high FGF23, low serum phosphate, low maximum renal phosphate reabsorption threshold (TmP/GFR), and low 1,25-dihydroxy-vitamin D (1,25(OH)
Language	English
Publishing date	2021-10-09
Publishing country	United States
Document type	Case Reports
ZDB-ID	2821774-3
ISSN	2352-1872
ISSN	2352-1872
DOI	10.1016/j.bonr.2021.101142
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Article ; Online: Evaluation of Acebilustat, a Selective Inhibitor of Leukotriene B4 Biosynthesis, for Treatment of Outpatients With Mild-Moderate Coronavirus Disease 2019: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

2023 Volume 77, Issue 2, Page(s) 186–193

Abstract: Background: The vast majority of coronavirus disease 2019 (COVID-19) disease occurs in outpatients where treatment is limited to antivirals for high-risk subgroups. Acebilustat, a leukotriene B4 inhibitor, has potential to reduce inflammation and ... ...

Abstract	Background: The vast majority of coronavirus disease 2019 (COVID-19) disease occurs in outpatients where treatment is limited to antivirals for high-risk subgroups. Acebilustat, a leukotriene B4 inhibitor, has potential to reduce inflammation and symptom duration. Methods: In a single-center trial spanning Delta and Omicron variants, outpatients were randomized to 100 mg/d of oral acebilustat or placebo for 28 days. Patients reported daily symptoms via electronic query through day 28 with phone follow-up on day 120 and collected nasal swab samples on days 1-10. The primary outcome was sustained symptom resolution to day 28. Secondary 28-day outcomes included time to first symptom resolution, area under the curve (AUC) for longitudinal daily symptom scores, duration of viral shedding through day 10, and symptoms on day 120. Results: Sixty participants were randomized to each study arm. At enrollment, the median duration was 4 days (interquartile range, 3-5 days), and the median number of symptoms was 9 (7-11). Most patients (90%) were vaccinated, with 73% having neutralizing antibodies. A minority of participants (44%; 35% in the acebilustat arm and 53% in placebo) had sustained symptom resolution at day 28 (hazard ratio, 0.6 [95% confidence interval, .34-1.04]; P = .07 favoring placebo). There was no difference in the mean AUC for symptom scores over 28 days (difference in mean AUC, 9.4 [95% confidence interval, -42.1 to 60.9]; P = .72). Acebilustat did not affect viral shedding or symptoms at day 120. Conclusions: Sustained symptoms through day 28 were common in this low-risk population. Despite this, leukotriene B4 antagonism with acebilustat did not shorten symptom duration in outpatients with COVID-19. Clinical Trials Registration. NCT04662060.
MeSH term(s)	Humans ; COVID-19 ; SARS-CoV-2 ; Leukotriene B4 ; Outpatients ; Double-Blind Method ; Treatment Outcome
Chemical Substances	acebilustat ; Leukotriene B4 (1HGW4DR56D)
Language	English
Publishing date	2023-03-30
Publishing country	United States
Document type	Randomized Controlled Trial ; Clinical Trial, Phase II ; Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1099781-7
ISSN	1537-6591 ; 1058-4838
ISSN (online)	1537-6591
ISSN	1058-4838
DOI	10.1093/cid/ciad187
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Zs.A 1505: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Atypical proximal femoral fractures in patients with paget disease receiving bisphosphonate therapy.

Kilcoyne, Aoife / Heffernan, Eric J

AJR. American journal of roentgenology

2011 Volume 197, Issue 1, Page(s) W196–7

MeSH term(s)	Aged ; Bone Density Conservation Agents/adverse effects ; Diphosphonates/adverse effects ; Female ; Femoral Fractures/chemically induced ; Femoral Fractures/diagnostic imaging ; Humans ; Middle Aged ; Osteoporosis, Postmenopausal/drug therapy ; Radiography
Chemical Substances	Bone Density Conservation Agents ; Diphosphonates
Language	English
Publishing date	2011-07
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	82076-3
ISSN	1546-3141 ; 0361-803X ; 0092-5381
ISSN (online)	1546-3141
ISSN	0361-803X ; 0092-5381
DOI	10.2214/AJR.10.6343
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Article ; Online: The Expanding Profile of the International Day of Radiology on Twitter.

Kelly, Brendan S / Redmond, Ciaran E / Horgan, Niall A / Healy, Gerard M / Heffernan, Eric J

Journal of the American College of Radiology : JACR

2016 Volume 13, Issue 6, Page(s) 604–605

MeSH term(s)	Humans ; Radiography ; Radiology ; Social Media
Language	English
Publishing date	2016
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2016.02.025
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Article ; Online: The evolution of whole-body imaging.

Moran, Deirdre E / Heffernan, Eric J

Seminars in musculoskeletal radiology

2010 Volume 14, Issue 1, Page(s) 3–13

Abstract: This article reviews the evolution of whole-body imaging, discussing the history and development of radiography, nuclear medicine, computed tomography (CT), positron emission tomography (PET), combined PET-CT, and magnetic resonance imaging. The ... ...

Abstract	This article reviews the evolution of whole-body imaging, discussing the history and development of radiography, nuclear medicine, computed tomography (CT), positron emission tomography (PET), combined PET-CT, and magnetic resonance imaging. The obstacles hindering progress toward whole-body imaging using each of these modalities, and the technical advances that were developed to overcome them, are reviewed. The effectiveness and the limitations of whole-body imaging with each of these techniques are also briefly discussed.
MeSH term(s)	History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Magnetic Resonance Imaging/history ; Positron-Emission Tomography/history ; Radiography/history ; Radionuclide Imaging/history ; Tomography, X-Ray Computed/history ; Whole Body Imaging/history
Language	English
Publishing date	2010-03
Publishing country	United States
Document type	Historical Article ; Journal Article
ZDB-ID	1360919-1
ISSN	1098-898X ; 1089-7860
ISSN (online)	1098-898X
ISSN	1089-7860
DOI	10.1055/s-0030-1248701
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Article ; Online: The Integration of Active Learning Teaching Strategies Into a Radiology Rotation for Medical Students Improves Radiological Interpretation Skills and Attitudes Toward Radiology.

Redmond, Ciaran E / Healy, Gerard M / Fleming, Hannah / McCann, Jeffrey W / Moran, Deirdre E / Heffernan, Eric J

Current problems in diagnostic radiology

2019 Volume 49, Issue 6, Page(s) 386–391

Abstract: Purpose: In recent years, there has been increased recognition of the benefits of teaching by active learning. However, there is a paucity of experimental studies utilizing active learning in undergraduate radiology rotations, which is traditionally a ... ...

Abstract	Purpose: In recent years, there has been increased recognition of the benefits of teaching by active learning. However, there is a paucity of experimental studies utilizing active learning in undergraduate radiology rotations, which is traditionally a passive learning experience. We designed a new radiology rotation that integrated teaching by active learning. We prospectively examined the efficacy of this new rotation compared to our standard rotation in terms of students' radiological competency and attitudes toward radiology, as well as impact on departmental efficiency. Methods: This was a prospective cohort study involving fourth year medical students completing a 1-week radiology rotation at our department between January and April 2018. One cohort completed a rotational model which incorporated active learning sessions (integrated cohort) while the remainder were taught using traditional passive learning methods (standard cohort). All participants completed a radiology examination before and after the rotation and were surveyed on their attitudes toward radiology. Results: A total of 105 students enrolled in the study. The mean postrotation competency score obtained by the integrated cohort was significantly higher than that obtained by the standard cohort (82% vs 62%; P < 0.001). The integrated rotation freed up 7 hours of radiologists' time per week. While the students completing the integrated rotation had a more positive perception of radiology, they were no more likely to express a desire to pursue a career in radiology. Conclusions: The integration of active learning sessions into an undergraduate radiology rotation results in an improvement in students' postrotation radiological competency and attitudes toward radiology.
MeSH term(s)	Attitude of Health Personnel ; Clinical Competence ; Education, Medical, Undergraduate ; Educational Measurement ; Efficiency, Organizational ; Female ; Humans ; Male ; Problem-Based Learning/methods ; Prospective Studies ; Radiology/education ; Young Adult
Language	English
Publishing date	2019-07-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	198954-6
ISSN	1535-6302 ; 0363-0188
ISSN (online)	1535-6302
ISSN	0363-0188
DOI	10.1067/j.cpradiol.2019.07.007
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Se 233: Show issues

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Article: Artifact on PET/CT secondary to FDG accumulation in a vaginal tampon.

Heffernan, Eric J / Skehan, Stephen J

Clinical nuclear medicine

2007 Volume 32, Issue 3, Page(s) 208–209

MeSH term(s)	Adult ; Artifacts ; Female ; Fluorodeoxyglucose F18/pharmacokinetics ; Humans ; Melanoma/diagnostic imaging ; Menstrual Hygiene Products ; Positron-Emission Tomography ; Radiopharmaceuticals/pharmacokinetics ; Tomography, X-Ray Computed
Chemical Substances	Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2007-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/01.rlu.0000255018.37567.fd
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