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  1. Article ; Online: Discovery of flat seismic reflections in the mantle beneath the young Juan de Fuca Plate.

    Qin, Yanfang / Singh, Satish C / Grevemeyer, Ingo / Marjanović, Milena / Roger Buck, W

    Nature communications

    2020  Volume 11, Issue 1, Page(s) 4122

    Abstract: ... 51-2.67 Ma old Juan de Fuca Plate. We find that the observed reflectors originate from 300-600-m ...

    Abstract Crustal properties of young oceanic lithosphere have been examined extensively, but the nature of the mantle lithosphere underneath remains elusive. Using a novel wide-angle seismic imaging technique, here we show the presence of two sub-horizontal reflections at ∼11 and ∼14.5 km below the seafloor over the 0.51-2.67 Ma old Juan de Fuca Plate. We find that the observed reflectors originate from 300-600-m-thick layers, with an ∼7-8% drop in P-wave velocity. They could be explained either by the presence of partially molten sills or frozen gabbroic sills. If partially molten, the shallower sill would define the base of a thin lithosphere with the constant thickness (11 km), requiring the presence of a mantle thermal anomaly extending up to 2.67 Ma. In contrast, if these reflections were frozen melt sills, they would imply the presence of thick young oceanic lithosphere (20-25 km), and extremely heterogeneous upper mantle.
    Language English
    Publishing date 2020-08-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-17946-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Conference proceedings ; Online: Seismic evidence of the lithosphere-asthenosphere boundary in the young Juan de Fuca Plate

    Qin, Yanfang / Singh, Satish C. / Grevemeyer, Ingo

    2018  

    Abstract: The lithosphere-asthenosphere boundary (LAB) is the most prevalent plate boundary on earth, but its definition and nature remains a matter of debate. Using wide-angle ocean bottom seismic (OBS) data, here we present the very first reflection image of the ...

    Abstract The lithosphere-asthenosphere boundary (LAB) is the most prevalent plate boundary on earth, but its definition and nature remains a matter of debate. Using wide-angle ocean bottom seismic (OBS) data, here we present the very first reflection image of the LAB over young oceanic lithosphere. The OBS data were acquired in 1996 to image the crustal structure, but advanced processing of these data show the presence of two wide-angle reflections originating from within the mantle. We first perform forward modeling to exclude the possibility of multiples and show these events are real. Based on tomographic velocity model, we perform migration and find that these reflections are continuous over 25-30 km distance and originate at 14 km and 19 km below the sea surface for ~2.6 Ma Oceanic Lithosphere. These seismic reflections lie several kilometers below the Moho, and the seismic forward modeling requires these reflections to originate from velocity discontinuities, which could relate to the presence of melts in the mantle that create the low velocity anomalies, therefore we suggest that they may define the LAB. These observations provide constrain of the depth, distribution and physical properties of the LAB transition zone, combined with the recent study of Mehouachi and Singh (2018), suggest that the LAB could consists of melt rich layers.
    Subject code 550
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Discovery of flat seismic reflections in the mantle beneath the young Juan de Fuca Plate

    Yanfang Qin / Satish C. Singh / Ingo Grevemeyer / Milena Marjanović / W. Roger Buck

    Nature Communications, Vol 11, Iss 1, Pp 1-

    2020  Volume 12

    Abstract: ... Juan de Fuca plate. ...

    Abstract Applying seismic imaging methods on ocean bottom hydrophone data, the authors here describe a horizontal, flat lithosphere base plus lithosphere-asthenosphere boundary beneath the young (0.51 to 2.67 Ma) Juan de Fuca plate.
    Keywords Science ; Q
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Discovery of flat seismic reflections in the mantle beneath the young Juan de Fuca Plate

    Qin, Yanfang / Singh, Satish C. / Grevemeyer, Ingo / Marjanović, Milena / Roger Buck, W.

    2020  

    Abstract: ... 51–2.67 Ma old Juan de Fuca Plate. We find that the observed reflectors originate from 300–600-m ...

    Abstract Crustal properties of young oceanic lithosphere have been examined extensively, but the nature of the mantle lithosphere underneath remains elusive. Using a novel wide-angle seismic imaging technique, here we show the presence of two sub-horizontal reflections at ∼11 and ∼14.5 km below the seafloor over the 0.51–2.67 Ma old Juan de Fuca Plate. We find that the observed reflectors originate from 300–600-m-thick layers, with an ∼7–8% drop in P-wave velocity. They could be explained either by the presence of partially molten sills or frozen gabbroic sills. If partially molten, the shallower sill would define the base of a thin lithosphere with the constant thickness (11 km), requiring the presence of a mantle thermal anomaly extending up to 2.67 Ma. In contrast, if these reflections were frozen melt sills, they would imply the presence of thick young oceanic lithosphere (20–25 km), and extremely heterogeneous upper mantle.
    Subject code 550
    Language English
    Publishing date 2020-12-17
    Publisher Nature Research
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book: Sui Tang juan

    Qin, Xu

    shang bian

    (Zhonghua yi shu tong shi ; / Li Xifan zong zhubian[...])

    2006  

    Author's details Qin Xu ben juan zhubian
    Series title Zhonghua yi shu tong shi
    / Li Xifan zong zhubian[...]
    Language Chinese
    Size 5, 551 p, Ill
    Edition Di 1 ban
    Publisher Beijing shifan daxue chubanshe
    Publishing place Beijing
    Document type Book
    ISBN 7303076972 ; 9787303076970
    Database Former special subject collection: coastal and deep sea fishing

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  6. Article ; Online: Genetic, Clinical, and Pathologic Backgrounds of Children With X-Linked Alport Syndrome in China: A Monocenter Study.

    Juan-Juan, Ding / Jia, Wang / Li-Li, Liu / Si, Wang / Xiao-Wen, Wang / Jiang-Wei, Luan / Li-Qin, Ke / Jie, Sun / Pei-Wei, Zhao

    Global pediatric health

    2024  Volume 11, Page(s) 2333794X231221935

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2785531-4
    ISSN 2333-794X ; 2333-794X
    ISSN (online) 2333-794X
    ISSN 2333-794X
    DOI 10.1177/2333794X231221935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Microbial interactions within Chinese traditional medicinal plants.

    Chen, Juan / Qin, Luping

    Chinese herbal medicines

    2024  Volume 16, Issue 2, Page(s) 169–171

    Language English
    Publishing date 2024-04-24
    Publishing country Singapore
    Document type Editorial
    ISSN 2589-3610
    ISSN (online) 2589-3610
    DOI 10.1016/j.chmed.2024.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Aporphine and amide alkaloids from Illigera parviflora.

    Xu, Juan-Juan / Yin, Yue-Ping / Wei, Wei / Tan, Qin-Gang

    Fitoterapia

    2023  Volume 172, Page(s) 105737

    Abstract: Three undescribed alkaloids (+)-9-hydroxy-N-acetylnordicentrine (1), illigeparvinine (2), and deca-(2E,4Z)-2,4-dienoic acid 4-hydroxy-2-phenethyl amide (3), along with 19 known analogues (4-22), were isolated from the ethnic medicinal plant Illigera ... ...

    Abstract Three undescribed alkaloids (+)-9-hydroxy-N-acetylnordicentrine (1), illigeparvinine (2), and deca-(2E,4Z)-2,4-dienoic acid 4-hydroxy-2-phenethyl amide (3), along with 19 known analogues (4-22), were isolated from the ethnic medicinal plant Illigera parviflora. Their structures were established using NMR, MS, and other spectroscopic analyses as well as X-ray diffraction. Moderate inhibition of human gastric carcinoma (MGC-803) and breast adenocarcinoma (T-47D) cell lines proliferation was observed for actinodaphnine (4) with IC
    MeSH term(s) Humans ; Molecular Structure ; Alkaloids/pharmacology ; Alkaloids/metabolism ; Aporphines/pharmacology ; Plants, Medicinal/chemistry ; Magnetic Resonance Spectroscopy ; Hernandiaceae/chemistry ; Hernandiaceae/metabolism
    Chemical Substances Alkaloids ; Aporphines
    Language English
    Publishing date 2023-11-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2023.105737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1873: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Data mining and safety analysis of traditional immunosuppressive drugs: a pharmacovigilance investigation based on the FAERS database.

    Li, Juan-Juan / Chen, Li / Zhao, Yang / Yang, Xue-Qin / Hu, Fa-Bin / Wang, Li

    Expert opinion on drug safety

    2024  Volume 23, Issue 4, Page(s) 513–525

    Abstract: Objective: The purpose of this study aimed to explore the new and serious adverse events(AEs) of Tacrolimus(FK506), cyclosporine(CsA), azathioprine(AZA), mycophenolate mofetil(MMF), cyclophosphamide(CTX) and methotrexate(MTX), which have not been ... ...

    Abstract Objective: The purpose of this study aimed to explore the new and serious adverse events(AEs) of Tacrolimus(FK506), cyclosporine(CsA), azathioprine(AZA), mycophenolate mofetil(MMF), cyclophosphamide(CTX) and methotrexate(MTX), which have not been concerned.
    Methods: The FAERS data from January 2016 and December 2022 were selected for disproportionality analysis to discover the potential risks of traditional immunosuppressive drugs.
    Results: Compared with CsA, FK506 has more frequent transplant rejection, and is more related to renal impairment, COVID-19, cytomegalovirus infection and aspergillus infection. However, CsA has a high infection-related fatality rate. In addition, we also found some serious and rare AE in other drugs which were rarely reported in previous studies. For example, AZA is closely related to hepatosplenic T-cell lymphoma with high fatality rate and MTX is strongly related to hypofibrinogenemia.
    Conclusion: The AEs report on this study confirmed that the results were basically consistent with the previous studies, but there were also some important safety signals that were inconsistent with or not mentioned in previous published studies.
    Expert opinion: The opinion section discusses some of the limitations and shortcomings, proposing the areas where more effort should be invested in order to improve the safety of immunosuppressive drugs.
    MeSH term(s) Humans ; Tacrolimus/adverse effects ; Pharmacovigilance ; Kidney Transplantation ; Immunosuppressive Agents/adverse effects ; Cyclosporine/adverse effects ; Mycophenolic Acid ; Methotrexate ; Data Mining ; Graft Rejection
    Chemical Substances Tacrolimus (WM0HAQ4WNM) ; Immunosuppressive Agents ; Cyclosporine (83HN0GTJ6D) ; Mycophenolic Acid (HU9DX48N0T) ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088728-0
    ISSN 1744-764X ; 1474-0338
    ISSN (online) 1744-764X
    ISSN 1474-0338
    DOI 10.1080/14740338.2024.2327503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6096: Show issues Location:
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  10. Article: Two Novel

    Qiao, Guanghang / Zhao, Juan / Liu, Juanjuan / Tan, Xiaoqian / Qin, Wentao

    Biology

    2022  Volume 11, Issue 10

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2022-10-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11101459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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