LIVIVO - Search results -

Search results

Result 1 - 10 of total 37

Search options

Article ; Online: Protein-Specific Signal Peptides for Mammalian Vector Engineering.

O'Neill, Pamela / Mistry, Rajesh K / Brown, Adam J / James, David C

ACS synthetic biology

2023 Volume 12, Issue 8, Page(s) 2339–2352

Abstract: Expression of recombinant proteins in mammalian cell factories relies on synthetic assemblies of genetic parts to optimally control flux through the product biosynthetic pathway. In comparison to other genetic part-types, there is a relative paucity of ... ...

Abstract	Expression of recombinant proteins in mammalian cell factories relies on synthetic assemblies of genetic parts to optimally control flux through the product biosynthetic pathway. In comparison to other genetic part-types, there is a relative paucity of characterized signal peptide components, particularly for mammalian cell contexts. In this study, we describe a toolkit of signal peptide elements, created using bioinformatics-led and synthetic design approaches, that can be utilized to enhance production of biopharmaceutical proteins in Chinese hamster ovary cell factories. We demonstrate, for the first time in a mammalian cell context, that machine learning can be used to predict how discrete signal peptide elements will perform when utilized to drive endoplasmic reticulum (ER) translocation of specific single chain protein products. For more complex molecular formats, such as multichain monoclonal antibodies, we describe how a combination of in silico and targeted design rule-based in vitro testing can be employed to rapidly identify product-specific signal peptide solutions from minimal screening spaces. The utility of this technology is validated by deriving vector designs that increase product titers ≥1.8×, compared to standard industry systems, for a range of products, including a difficult-to-express monoclonal antibody. The availability of a vastly expanded toolbox of characterized signal peptide parts, combined with streamlined in silico/in vitro testing processes, will permit efficient expression vector re-design to maximize titers of both simple and complex protein products.
MeSH term(s)	Cricetinae ; Animals ; Cricetulus ; CHO Cells ; Protein Sorting Signals/genetics ; Recombinant Proteins/metabolism ; Antibodies, Monoclonal/metabolism
Chemical Substances	Protein Sorting Signals ; Recombinant Proteins ; Antibodies, Monoclonal
Language	English
Publishing date	2023-07-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2161-5063
ISSN (online)	2161-5063
DOI	10.1021/acssynbio.3c00157
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis.

Mistry, Rajesh K / Brewer, Alison C

Free radical biology & medicine

2017 Volume 108, Page(s) 500–516

Abstract: Reactive oxygen species have emerged as key participants in a broad range of physiological and pathophysiological processes, not least within the vascular system. Diverse cellular functions which have been attributed to some of these pro-oxidants within ... ...

Abstract	Reactive oxygen species have emerged as key participants in a broad range of physiological and pathophysiological processes, not least within the vascular system. Diverse cellular functions which have been attributed to some of these pro-oxidants within the vasculature include the regulation of blood pressure, neovascularisation and vascular inflammation. We here highlight the emerging roles of the enzymatically-generated reaction oxygen species, O
MeSH term(s)	Animals ; Cardiovascular System/metabolism ; Gasotransmitters/metabolism ; Gene Expression Regulation ; Humans ; Neovascularization, Physiologic ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism
Chemical Substances	Gasotransmitters ; Reactive Oxygen Species ; Vascular Endothelial Growth Factor A
Language	English
Publishing date	2017-04-19
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	807032-5
ISSN	1873-4596 ; 0891-5849
ISSN (online)	1873-4596
ISSN	0891-5849
DOI	10.1016/j.freeradbiomed.2017.04.025
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2109: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Profile of Dengue Fever in Hospitalized Children in Saurashtra, Gujarat, 2013-2017.

Mistry, Madhulika / Chudasama, Rajesh K / Goswami, Yogesh

Indian pediatrics

2019 Volume 56, Issue 2, Page(s) 123–125

Abstract: Objective: To study the five year trend of epidemiological and demographic characteristics of dengue infections from year 2013 to 2017 among children upto 15 years.: Methods: This study presents data from review of microbiology department records of ... ...

Abstract	Objective: To study the five year trend of epidemiological and demographic characteristics of dengue infections from year 2013 to 2017 among children upto 15 years. Methods: This study presents data from review of microbiology department records of samples for dengue testing with information supplied by clinicians on the investigation request form. Patients were tested for NS1 Ag, IgM Ab or both. Results: Out of 4216 samples, 1072 (25.4%) were positive for dengue. Positivity ranged from 44.2% in year 2013, 25.8% in 2015 to 16.2% in year 2017. Most cases reported were among male (57.9%), from urban areas (77.9%) and Rajkot district (75.7%). Reporting of dengue cases increased from July to November with peak during October every year. Conclusions: Serum samples for dengue serology were more commonly positive in July-September months during the study period, and in male children, and those from urban areas.
MeSH term(s)	Adolescent ; Child ; Child, Preschool ; Dengue/epidemiology ; Dengue/transmission ; Female ; Hospitalization ; Humans ; India/epidemiology ; Infant ; Infant, Newborn ; Male ; Seasons
Language	English
Publishing date	2019-03-01
Publishing country	India
Document type	Journal Article
ZDB-ID	402594-5
ISSN	0974-7559 ; 0019-6061
ISSN (online)	0974-7559
ISSN	0019-6061
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 859: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Redox-Dependent Regulation of Sulfur Metabolism in Biomolecules: Implications for Cardiovascular Health.

Mistry, Rajesh K / Brewer, Alison C

Antioxidants & redox signaling

2017 Volume 30, Issue 7, Page(s) 972–991

Abstract: Significance: Sulfur-containing amino acids are integral to the molecular mechanisms that underlie many aspects of cellular function and homeostasis, facilitated by reversible changes in the oxidation states of sulfur atoms. Sulfur-containing amino ... ...

Abstract	Significance: Sulfur-containing amino acids are integral to the molecular mechanisms that underlie many aspects of cellular function and homeostasis, facilitated by reversible changes in the oxidation states of sulfur atoms. Sulfur-containing amino acids are metabolically linked by interacting pathways that impact the one-carbon metabolic cycle and generation of methyl groups, the folate cycle, and maintenance of the major cellular redox buffer; glutathione. Dysregulation of these pathways is associated with diverse pathologies, notably of the cardiovascular (CV) system, which are typically characterized by inappropriate plasma levels of sulfur-containing amino acids. Recent Advances: Perhaps not surprisingly, the cellular redox state has emerged as a major regulator of many enzymatic processes within these metabolic cycles. The metabolism of cysteine can also result in the production of hydrogen sulfide (H Critical issues: In most cases, the endogenous physiological sources of ROS that might mediate the interlinked metabolic pathways of sulfur-containing biomolecules remain unknown. However, the family of NADPH oxidases, and Nox4 in particular, is emerging as a likely candidate. Future directions: This review focuses on the current knowledge of key aspects of sulfur metabolism, which are regulated by redox-based chemical reactions, and the likely intracellular oxidant sources that might mediate this regulation. This knowledge will be important to guide future targeted therapeutic interventions in diverse CV disorders.
MeSH term(s)	Amino Acids/metabolism ; Animals ; Cardiovascular Diseases/metabolism ; Humans ; Hydrogen Sulfide/metabolism ; Metabolic Networks and Pathways ; Oxidation-Reduction ; Sulfur/metabolism
Chemical Substances	Amino Acids ; Sulfur (70FD1KFU70) ; Hydrogen Sulfide (YY9FVM7NSN)
Language	English
Publishing date	2017-07-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1483836-9
ISSN	1557-7716 ; 1523-0864
ISSN (online)	1557-7716
ISSN	1523-0864
DOI	10.1089/ars.2017.7224
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5488: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Intermuscular Subcutaneous Implantable Cardioverter-Defibrillator Implantation Without Defibrillation Testing.

Mistry, Amar / Pooranachandran, Vivetha / Dhutia, Harshil / Chelliah, Rajesh / Pathmanathan, Ravi K

JACC. Clinical electrophysiology

2020 Volume 7, Issue 1, Page(s) 124–126

MeSH term(s)	Defibrillators, Implantable ; Electric Countershock ; Humans ; Ventricular Fibrillation
Language	English
Publishing date	2020-10-28
Publishing country	United States
Document type	Letter
ZDB-ID	2846739-5
ISSN	2405-5018 ; 2405-500X ; 2405-500X
ISSN (online)	2405-5018 ; 2405-500X
ISSN	2405-500X
DOI	10.1016/j.jacep.2020.09.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A novel hydrogen peroxide evolved CHO host can improve the expression of difficult to express bispecific antibodies.

Mistry, Rajesh K / Kelsall, Emma / Sou, Si Nga / Barker, Harriet / Jenns, Mike / Willis, Katie / Zurlo, Fabio / Hatton, Diane / Gibson, Suzanne J

Biotechnology and bioengineering

2021 Volume 118, Issue 6, Page(s) 2326–2337

Abstract: The manufacture of bispecific antibodies by Chinese hamster ovary (CHO) cells is often hindered by lower product yields compared to monoclonal antibodies. Recently, reactive oxygen species have been shown to negatively impact antibody production. By ... ...

Abstract	The manufacture of bispecific antibodies by Chinese hamster ovary (CHO) cells is often hindered by lower product yields compared to monoclonal antibodies. Recently, reactive oxygen species have been shown to negatively impact antibody production. By contrast, strategies to boost cellular antioxidant capacity appear to be beneficial for recombinant protein expression. With this in mind, we generated a novel hydrogen peroxide evolved host using directed host cell evolution. Here we demonstrate that this host has heritable resistance to hydrogen peroxide over many generations, displays enhanced antioxidant capacity through the upregulation of several, diverse antioxidant defense genes such as those involved in glutathione synthesis and turnover, and has improved glutathione content. Additionally, we show that this host has significantly improved transfection recovery times, improved growth and viability properties in a fed-batch production process, and elevated expression of two industrially relevant difficult to express bispecific antibodies compared to unevolved CHO control host cells. These findings demonstrate that host cell evolution represents a powerful methodology for improving specific host cell characteristics that can positively impact the expression of difficult to express biotherapeutics.
MeSH term(s)	Animals ; Antibodies, Bispecific/biosynthesis ; CHO Cells/classification ; Cricetulus ; Hydrogen Peroxide ; Oxidative Stress ; Recombinant Proteins/biosynthesis ; Transfection
Chemical Substances	Antibodies, Bispecific ; Recombinant Proteins ; Hydrogen Peroxide (BBX060AN9V)
Language	English
Publishing date	2021-03-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	280318-5
ISSN	1097-0290 ; 0006-3592
ISSN (online)	1097-0290
ISSN	0006-3592
DOI	10.1002/bit.27744
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 960: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Assessing the effectiveness of gabapentin in paclitaxel-induced arthralgia, myalgia, and neuropathic pain: An observational, cohort study.

Patel, Prashantkumar / Rajput, Hemraj Singh / Chavda, Khushboo / Mistry, Smit / Bhagat, Sandesh / Hadia, Rajesh / Saiyed, Moinuddin / Khadela, Avinash

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2024 , Page(s) 10781552231225148

Abstract: Background and objectives: Arthralgia, myalgia, and neuropathic pain are the most common side effects observed due to paclitaxel chemotherapy. The aim of this study was to investigate the prophylactic role, maintenance, remission, and re-occurrence of ... ...

Abstract	Background and objectives: Arthralgia, myalgia, and neuropathic pain are the most common side effects observed due to paclitaxel chemotherapy. The aim of this study was to investigate the prophylactic role, maintenance, remission, and re-occurrence of arthralgia, myalgia, and neuropathic pain post-gabapentin therapy. Methodology: This study was conducted in the Department of Oncology, Dhiraj Hospital, Vadodara with a sample of 51 patients. Newly detected cancer patients who observed arthralgia, myalgia, and neuropathic pain due to paclitaxel were taken and a baseline pain assessment was done using the Common Terminology Criteria for Adverse Events (CTCAE) and painDETECT questionnaire. Gabapentin was given in the first cycle after symptoms appeared and prophylactic treatment was given in the subsequent three cycles and evaluation of pain was done post-gabapentin therapy to assess the symptomatic as well as prophylactic effect. Results: At baseline, neuropathic pain score was 22.7 ± 3.6 which reduced to 0.01 ± 0.14 on subsequent follow-ups. Grade 2 arthralgia, myalgia, and neuropathic pain were more observed at baseline which reduces to Grade 0 in the third cycle. The difference in baseline and post-gabapentin therapy was statistically analyzed by conducting Conclusion: This study shows that gabapentin reduces neuropathic pain. Prophylactic usage of gabapentin was highly effective at bringing about quick pain relief when compared to symptomatic treatment. In further follow-ups, it was noted that gabapentin maintained the impact throughout the cycles.
Language	English
Publishing date	2024-01-05
Publishing country	England
Document type	Journal Article
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552231225148
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4488: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Stereotactic body radiotherapy for lung tumors: Dosimetric analysis and clinical outcome.

Talapatra, Kaustav / Majumder, Dipanjan / Chadha, Pranav / Shaju, P / Goyle, Sandeep / Smruti, B K / Mistry, Rajesh

Indian journal of cancer

2019 Volume 55, Issue 2, Page(s) 170–175

Abstract: Introduction: Stereotactic body radiotherapy (SBRT) has emerged as an important modality in malignant lung tumor treatment both in early localized primary and oligometastatic setting. This study aims to present the results of lung SBRT both in terms of ... ...

Abstract	Introduction: Stereotactic body radiotherapy (SBRT) has emerged as an important modality in malignant lung tumor treatment both in early localized primary and oligometastatic setting. This study aims to present the results of lung SBRT both in terms of dosimetry and clinical outcome. Materials and methods: Twenty-seven patients were assessed from 2012 to 2016. Both the primary and oligometastatic lung tumors were evaluated. Respiratory motion management was done employing ANZAI (Siemens, Germany) based four-dimensional computed tomography (CT). Commonly used fractionations were 60 Gy/5 fractions for peripheral tumors and 48 Gy/6 fractions for central tumors. Radiation Therapy Oncology Group toxicity criteria were used for toxicity and whole-body positron emission tomography-CT scan was done at follow-up for response evaluation. Results: Twenty-seven patients were evaluated, 18 (66.7%) patients had a primary, and 9 (33.3%) patients had metastatic lung tumors. The male-to-female ratio for the entire cohort was 2:1. The median age at diagnosis was 65.8 years. Mean planning target volume (PTV) D2cc was 54.9 ± 9.04 Gy and mean internal target volume diameter was 3.0 ± 1.07 cm. Mean V20 Gy, V10 Gy, and V5 Gy of (lungs total-PTV) and (Lung ipsilateral - PTV) were 5.4 ± 4% and 10.9 ± 7.9%, 11.7 ± 5.8% and 24.2 ± 14.0%, and 22.05 ± 12.4% and 33.2 ± 15.3%, respectively. In total 21 (84%) patients and 4 patients (16%) showed a complete and partial response, respectively. One (3%) patient developed Gr 3 radiation pneumonitis. One year local control was in 18 (81%) patients whereas 4 (14%) patients progressed and three patients did not report. A higher prescribed dose significantly correlated with 1 year tumor control (P = 0.036). Conclusion: This study infers the feasibility and a favorable outcome for lung cancer amenable to SBRT in addition to being one of the largest clinical experiences for lung stereotactic treatment in our country.
MeSH term(s)	Aged ; Female ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/radiotherapy ; Male ; Radiometry/methods ; Radiosurgery/methods ; Treatment Outcome
Language	English
Publishing date	2019-02-18
Publishing country	India
Document type	Journal Article
ZDB-ID	410194-7
ISSN	1998-4774 ; 0019-509X
ISSN (online)	1998-4774
ISSN	0019-509X
DOI	10.4103/ijc.IJC_555_17
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 581: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Epidemiological characteristics of dengue disease in Saurashtra region, India, during year 2015.

Mistry, Madhulika / Chudasama, Rajesh K / Goswami, Yogesh / Dalwadi, Chintan / Mitra, Aarohi / Mehta, Garima

Journal of family medicine and primary care

2017 Volume 6, Issue 2, Page(s) 249–253

Abstract: Background: Dengue is an important vector-borne disease with a spectrum of classical fever to hemorrhagic fever to dengue shock syndrome. The present study was conducted with objective to study epidemiological and demographic characteristics of dengue ... ...

Abstract	Background: Dengue is an important vector-borne disease with a spectrum of classical fever to hemorrhagic fever to dengue shock syndrome. The present study was conducted with objective to study epidemiological and demographic characteristics of dengue infections during the year 2015 in Saurashtra region, Gujarat state, India. Materials and methods: The study was conducted at Tertiary Care Hospital, Rajkot, during the year 2015. A total of 3312 blood samples were collected and tested for dengue NS1 antigen and IgM antibody by capture ELISA testing from various districts of Saurashtra region. A pretested structured data sheet was used as a tool for data collection, and data analysis was done. Results: Out of 3312 tested samples, 33.4% samples were found positive for dengue. Suspected cases were reported from all age groups, including majority from 15 to 24 years (31.1%) and 25 to 44 years (30.0%) and also 8.4% from 0 to 4 years. More than two-third (68.7%) of males were dengue positive than female cases. Significant numbers of cases ( Conclusion: The present study reported that dengue mainly affected males and urban population. Perennial occurrence with seasonal increase during monsoon and postmonsoon months was reported. Effective implementation of vector control measures through efforts toward vector breeding source reduction and with the use of personal prophylactic measures against mosquito bites will help in reducing the dengue prevalence in the community.
Language	English
Publishing date	2017-12-22
Publishing country	India
Document type	Journal Article
ZDB-ID	2735275-4
ISSN	2278-7135 ; 2249-4863
ISSN (online)	2278-7135
ISSN	2249-4863
DOI	10.4103/2249-4863.220003
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Epidemiological and demographic characteristics of dengue disease at a tertiary care centre in Saurashtra region during the year 2013.

Mistry, Madhulika / Goswami, Yogesh / Chudasama, Rajesh K / Thakkar, Dhara

Journal of vector borne diseases

2015 Volume 52, Issue 4, Page(s) 299–303

Abstract: Background & objectives: Dengue is one of the most important vector-borne viral infection which may lead to haemorrhage or even shock. The present study was conducted with an objective to study the epidemiological and demographic characteristics of ... ...

Abstract	Background & objectives: Dengue is one of the most important vector-borne viral infection which may lead to haemorrhage or even shock. The present study was conducted with an objective to study the epidemiological and demographic characteristics of dengue disease during the year 2013 in Saurashtra region of Gujarat state, India. Methods: A longitudinal study was conducted at sentinel surveillance centre for dengue disease at microbiology department of tertiary care hospital in Rajkot, Gujarat from 1 January 2013 to 31 December 2013. A total of 4366 blood samples were collected during study period and serologically tested for dengue NS1 antigen and IgM antibody by capture ELISA testing from various districts of Saurashtra region. Patients with acute onset of illness, high grade fever, severe headache, backache, musculoskeletal pain or retro-bulbar pain with or without rashes were considered as clinically suspected case of dengue virus infection. Patient who presented with fever and found positive for Dengue NS1 Ag and/or IgM Ab was considered as a case. A pre-tested structured proforma was used as a tool for data collection. The data was entered into EpiInfo software and analyzed by using appropriate statistical test (chi-square test). Results: Out of 4366 tested samples, 41.3% samples were found positive for dengue. Majority of samples were tested in age group 16-25 yr (33.9%) and 26-45 yr (31.1%). The ratio of male cases (60.8%) was higher than female cases. Two-third (68.7%) suspected cases were residing in urban areas of Saurashtra region. More than half of the cases (57%) were diagnosed within five days of fever by NS1 antigen test. The reporting of number of cases increased from July 2013, which reached to peak during September 2013 followed by decrease till December 2013. Interpretation & conclusion: Dengue predominately affected males and urban population. A seasonal occurrence was reported mainly during monsoon season. A long term serosurveillance study may help to provide more information about the intensity, seasonal incidence and seasonal effect.
MeSH term(s)	Adolescent ; Adult ; Aged ; Antibodies, Viral/blood ; Child ; Child, Preschool ; Dengue/blood ; Dengue/epidemiology ; Dengue Virus/immunology ; Dengue Virus/isolation & purification ; Female ; Humans ; India/epidemiology ; Infant ; Longitudinal Studies ; Male ; Middle Aged ; Tertiary Care Centers ; Young Adult
Chemical Substances	Antibodies, Viral
Language	English
Publishing date	2015-12-29
Publishing country	India
Document type	Journal Article
ZDB-ID	2161218-3
ISSN	0972-9062
ISSN	0972-9062
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh II Zs.222: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito