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  1. Article ; Online: Reducing mask resistance among White evangelical Christians with value-consistent messages.

    DeMora, Stephanie L / Merolla, Jennifer L / Newman, Brian / Zechmeister, Elizabeth J

    Proceedings of the National Academy of Sciences of the United States of America

    2021  Volume 118, Issue 21

    Abstract: Public health experts have advocated for wearing protective face masks to combat the COVID-19 pandemic, yet some populations are resistant. Can certain messages shift attitudes toward masks? We investigate the effect of value-consistent messages within a ...

    Abstract Public health experts have advocated for wearing protective face masks to combat the COVID-19 pandemic, yet some populations are resistant. Can certain messages shift attitudes toward masks? We investigate the effect of value-consistent messages within a mask-skeptical population: White evangelicals in the United States. An experiment within a national survey of White evangelicals (
    MeSH term(s) Attitude to Health ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/psychology ; Health Communication/methods ; Humans ; Masks ; Protestantism/psychology ; Public Opinion ; SARS-CoV-2 ; Surveys and Questionnaires ; United States/epidemiology
    Language English
    Publishing date 2021-05-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2101723118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126.

    McDonald, Andrew M / DeMora, Lyudmila / Yang, Eddy S / Hoyle, John M / Lenzie, Andrew / Williams, Grant R / Michalski, Jeff M / Yee, Don / Bahary, Jean-Paul / Den, Robert B / Roach, Mack / Dess, Robert / Mishra, Mark V / Valicenti, Richard K / Lau, Harold Y / Marcrom, Samuel R / Souhami, Luis / Mendez, Lucas C / Chen, Yuhchyau /
    Doncals, Desiree E / Pugh, Stephanie L / Feng, Felix Y / Sandler, Howard M

    Cancer

    2022  Volume 129, Issue 5, Page(s) 685–696

    Abstract: Purpose: To validate the association between body composition and mortality in men treated with radiation for localized prostate cancer (PCa). Secondarily, to integrate body composition as a factor to classify patients by risk of all-cause mortality.: ...

    Abstract Purpose: To validate the association between body composition and mortality in men treated with radiation for localized prostate cancer (PCa). Secondarily, to integrate body composition as a factor to classify patients by risk of all-cause mortality.
    Materials and methods: Participants of NRG/Radiation Therapy Oncology Group (RTOG) 9406 and NRG/RTOG 0126 with archived computed tomography were included. Muscle mass and muscle density were estimated by measuring the area and attenuation of the psoas muscles on a single slice at L4-L5. Bone density was estimated by measuring the attenuation of the vertebral body at mid-L5. Survival analyses, including Cox proportional hazards models, assessed the relationship between body composition and mortality. Recursive partitioning analysis (RPA) was used to create a classification tree to classify participants by risk of death.
    Results: Data from 2066 men were included in this study. In the final multivariable model, psoas area, comorbidity score, baseline prostate serum antigen, and age were significantly associated with survival. The RPA yielded a classification tree with four prognostic groups determined by age, comorbidity, and psoas area. Notably, the classification among older (≥70 years) men into prognostic groups was determined by psoas area.
    Conclusions: This study strongly supports that body composition is related to mortality in men with localized PCa. The inclusion of psoas area in the RPA classification tree suggests that body composition provides additive information to age and comorbidity status for mortality prediction, particularly among older men. More research is needed to determine the clinical impact of body composition on prognostic models in men with PCa.
    MeSH term(s) Male ; Humans ; Aged ; Prostate ; Prostatic Neoplasms ; Prognosis ; Survival Analysis ; Body Composition
    Language English
    Publishing date 2022-12-29
    Publishing country United States
    Document type Meta-Analysis ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.34596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.146: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Breast conservation versus mastectomy in patients with T3 breast cancers (> 5 cm): an analysis of 37,268 patients from the National Cancer Database.

    Mazor, Anna M / Mateo, Alina M / Demora, Lyudmila / Sigurdson, Elin R / Handorf, Elizabeth / Daly, John M / Aggon, Allison A / Anderson, Penny R / Weiss, Stephanie E / Bleicher, Richard J

    Breast cancer research and treatment

    2018  Volume 173, Issue 2, Page(s) 301–311

    Abstract: Purpose: Breast conservation therapy (BCT) is standard for T1-T2 tumors, but early trials excluded breast cancers > 5 cm. This study was performed to assess patterns and outcomes of BCT for T3 tumors.: Methods: We reviewed the National Cancer ... ...

    Abstract Purpose: Breast conservation therapy (BCT) is standard for T1-T2 tumors, but early trials excluded breast cancers > 5 cm. This study was performed to assess patterns and outcomes of BCT for T3 tumors.
    Methods: We reviewed the National Cancer Database (NCDB) for noninflammatory breast cancers > 5 cm, between 2004 and 2011 who underwent BCT or mastectomy (Mtx) with nodal evaluation. Patients with skin or chest wall involvement were excluded. Patients having clinical T3 tumors were analyzed to determine outcomes based upon presentation, with those having pathologic T3 tumors, subsequently assessed, irrespective of presentation. Overall survival (OS) was analyzed using multivariable Cox proportional hazards models, with adjusted survival curves estimated using inverse probability weighting.
    Results: After exclusions, 37,268 patients remained. Median age and tumor size for BCT versus Mtx were 53 versus 54 years (p < 0.001) and 6.0 versus 6.7 cm (p < 0.001), respectively. Predictors of BCT included age, race, location, facility type, year of diagnosis, tumor size, grade, histology, nodes examined and positive, and administration of chemotherapy and radiotherapy. OS was similar between Mtx and BCT (p = 0.36). This held true when neoadjuvant chemotherapy patients were excluded (p = 0.39). BCT percentages declined over time (p < 0.001), while tumor sizes remained the same (p = 0.77). Median follow-up was 51.4 months.
    Conclusions: OS for patients with T3 breast cancers is similar whether patients received Mtx or BCT, confirming that tumor size should not be an absolute BCT exclusion. Declining use of BCT for tumors > 5 cm in younger patients may be accounted for by recent trends toward mastectomy.
    MeSH term(s) Adult ; Age Factors ; Aged ; Breast/pathology ; Breast/surgery ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Breast Neoplasms/therapy ; Chemoradiotherapy, Adjuvant/methods ; Databases, Factual/statistics & numerical data ; Female ; Humans ; Mastectomy/standards ; Mastectomy/statistics & numerical data ; Mastectomy/trends ; Mastectomy, Segmental/standards ; Mastectomy, Segmental/statistics & numerical data ; Mastectomy, Segmental/trends ; Middle Aged ; Neoadjuvant Therapy/methods ; Organ Sparing Treatments/standards ; Organ Sparing Treatments/statistics & numerical data ; Organ Sparing Treatments/trends ; Survival Analysis ; Treatment Outcome ; Tumor Burden ; United States/epidemiology
    Language English
    Publishing date 2018-10-20
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 604563-7
    ISSN 1573-7217 ; 0167-6806
    ISSN (online) 1573-7217
    ISSN 0167-6806
    DOI 10.1007/s10549-018-5007-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1655: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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