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  1. Article ; Online: Editorial: Is artificial intelligence changing the way we conduct research?

    McEachan, Jane E / Lam, Wee L

    The Journal of hand surgery, European volume

    2024  Volume 49, Issue 5, Page(s) 532–533

    MeSH term(s) Artificial Intelligence ; Humans ; Biomedical Research ; Research Design
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Editorial
    ZDB-ID 2272801-6
    ISSN 2043-6289 ; 1753-1934
    ISSN (online) 2043-6289
    ISSN 1753-1934
    DOI 10.1177/17531934241241911
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Health information report 1999 - 2001

    Wee, L. de / Matroos, E.

    2003  

    Author's details comp. by: L. de Wee ; E. Matroos
    Language English
    Size XIV, 98 S. : graph. Darst.
    Publisher Republic of Namibia, Ministry of Health and Social Services
    Publishing place Windhoek
    Publishing country Namibia
    Document type Book
    HBZ-ID HT014448303
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Gastrointestinal: A case of black stomach and duodenum.

    Ho, J L / Wee, Ewl / Wong, Bpk

    Journal of gastroenterology and hepatology

    2023  Volume 38, Issue 12, Page(s) 2050

    MeSH term(s) Humans ; Stomach/diagnostic imaging ; Gastrointestinal Tract ; Duodenum/diagnostic imaging ; Upper Gastrointestinal Tract
    Language English
    Publishing date 2023-08-09
    Publishing country Australia
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 632882-9
    ISSN 1440-1746 ; 0815-9319
    ISSN (online) 1440-1746
    ISSN 0815-9319
    DOI 10.1111/jgh.16317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Response to concerns about the increasing influence of artificial intelligence in publishing.

    McEachan, Jane E / Lam, Wee L

    The Journal of hand surgery, European volume

    2023  Volume 48, Issue 8, Page(s) 697–698

    MeSH term(s) Humans ; Artificial Intelligence ; Publishing
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Editorial
    ZDB-ID 2272801-6
    ISSN 2043-6289 ; 1753-1934
    ISSN (online) 2043-6289
    ISSN 1753-1934
    DOI 10.1177/17531934231183224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The volume and the distribution of premorbid white matter hyperintensities: Impact on post-stroke aphasia.

    Vadinova, Veronika / Sihvonen, A J / Wee, F / Garden, K L / Ziraldo, L / Roxbury, T / O'Brien, K / Copland, D A / McMahon, K L / Brownsett, S L E

    Human brain mapping

    2024  Volume 45, Issue 1, Page(s) e26568

    Abstract: White matter hyperintensities (WMH) are a radiological manifestation of progressive white matter integrity loss. The total volume and distribution of WMH within the corpus callosum have been associated with pathological cognitive ageing processes but ... ...

    Abstract White matter hyperintensities (WMH) are a radiological manifestation of progressive white matter integrity loss. The total volume and distribution of WMH within the corpus callosum have been associated with pathological cognitive ageing processes but have not been considered in relation to post-stroke aphasia outcomes. We investigated the contribution of both the total volume of WMH, and the extent of WMH lesion load in the corpus callosum to the recovery of language after first-ever stroke. Behavioural and neuroimaging data from individuals (N = 37) with a left-hemisphere stroke were included at the early subacute stage of recovery. Spoken language comprehension and production abilities were assessed using word and sentence-level tasks. Neuroimaging data was used to derive stroke lesion variables (volume and lesion load to language critical regions) and WMH variables (WMH volume and lesion load to three callosal segments). WMH volume did not predict variance in language measures, when considered together with stroke lesion and demographic variables. However, WMH lesion load in the forceps minor segment of the corpus callosum explained variance in early subacute comprehension abilities (t = -2.59, p = .01) together with corrected stroke lesion volume and socio-demographic variables. Premorbid WMH lesions in the forceps minor were negatively associated with early subacute language comprehension after aphasic stroke. This negative impact of callosal WMH on language is consistent with converging evidence from pathological ageing suggesting that callosal WMH disrupt the neural networks supporting a range of cognitive functions.
    MeSH term(s) Humans ; White Matter/diagnostic imaging ; White Matter/pathology ; Aphasia/diagnostic imaging ; Aphasia/etiology ; Cognition ; Stroke/complications ; Stroke/diagnostic imaging ; Stroke/pathology ; Aging ; Magnetic Resonance Imaging
    Language English
    Publishing date 2024-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.26568
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Congenital hand differences - where we currently are and what's next.

    Hovius, Steve E R / Lam, Wee L / Weber, Daniel M

    The Journal of hand surgery, European volume

    2022  Volume 47, Issue 10, Page(s) 1001–1003

    MeSH term(s) Humans ; Hand/surgery ; Upper Extremity
    Language English
    Publishing date 2022-09-25
    Publishing country England
    Document type Editorial
    ZDB-ID 2272801-6
    ISSN 2043-6289 ; 1753-1934
    ISSN (online) 2043-6289
    ISSN 1753-1934
    DOI 10.1177/17531934221127172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: VEXAS Syndrome and Thrombosis: Findings of Inflammation, Hypercoagulability, and Endothelial Dysfunction.

    Fan, Bingwen E / Sum, Christina L L / Leung, Bernard P L / Ang, Mui K / Lim, Xin R / Lee, Samuel S M / Koh, Li W / Goh, Liuh L / Chan, Wee L / Wang, Liang D / Wong, Siu L / Tay, Sen H

    Seminars in thrombosis and hemostasis

    2024  

    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196901-8
    ISSN 1098-9064 ; 0094-6176
    ISSN (online) 1098-9064
    ISSN 0094-6176
    DOI 10.1055/s-0043-1778105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Heat Treatments for Killing Apple Maggot Fly (Diptera: Tephritidae) Puparia for Application in Disinfesting Organic Yard Waste.

    Yee, Wee L / Kruger, Chad E / O'Neill, Tim

    Journal of economic entomology

    2022  Volume 115, Issue 2, Page(s) 493–500

    Abstract: Organic yard waste from western Washington, U.S. that may contain puparia of apple maggot fly, Rhagoletis pomonella (Walsh) (Diptera: Tephritidae), had been moved to central Washington for composting, threatening the $3 billion apple industry ... ...

    Abstract Organic yard waste from western Washington, U.S. that may contain puparia of apple maggot fly, Rhagoletis pomonella (Walsh) (Diptera: Tephritidae), had been moved to central Washington for composting, threatening the $3 billion apple industry concentrated in that region. Heating waste to kill fly puparia before it is transported could be a solution to this problem. Here, we report results of studies in 2016-2021 that sought to identify a minimum heat treatment simulating that obtained using a low-pressure steam generator for maximizing kill of R. pomonella puparia. In two experiments, puparia were exposed to temperatures ramped linearly over 6 h from 21°C to 47.8, 51.1, 55.0, or 60.0°C in an oven. The 47.8, 51.1, and 55°C treatments did not achieve 100% mortality, although only one adult fly from 4,000 puparia was found in the 55°C treatment, while no puparia survived the 60°C treatment. In a third, similar experiment, no puparia out of 2,400 exposed to 55°C survived. In a fourth and final experiment conducted over 3 years, no puparia out of 61,223 exposed to a 6-h ramp from 21°C to 55°C followed by a 1-h hold time at 55°C produced flies. In addition, all puparia in this treatment died. Based on 42.3 to 69.8% control survival, 31,217 puparia were killed by this treatment with no survivors, for a probit 8.7190 level of security. Results suggest that the 55°C and 1-h hold time treatment here is close to the minimum heat regime needed for disinfesting organic waste of R. pomonella puparia.
    MeSH term(s) Animals ; Diptera ; Hot Temperature ; Larva ; Tephritidae ; Washington
    Language English
    Publishing date 2022-02-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3031-4
    ISSN 1938-291X ; 0022-0493
    ISSN (online) 1938-291X
    ISSN 0022-0493
    DOI 10.1093/jee/toab269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Hyperinsulinemic Hypoglycemia and Growth Hormone Deficiency Secondary to 20p11 Deletion.

    Wee, Erica / Herriges, John / Dileepan, Kavitha / Tsai, Sarah L / Alaimo, Joseph T / Paprocki, Emily

    Case reports in endocrinology

    2023  Volume 2023, Page(s) 8658540

    Abstract: Hypoglycemia is concerning for neurological complications in infants and children. Determining the cause of hypoglycemia is essential in providing appropriate treatment. Hyperinsulinism and growth hormone deficiency are known causes of hypoglycemia but ... ...

    Abstract Hypoglycemia is concerning for neurological complications in infants and children. Determining the cause of hypoglycemia is essential in providing appropriate treatment. Hyperinsulinism and growth hormone deficiency are known causes of hypoglycemia but are not commonly found together. We report a 4-month-old boy who presented with severe hypoglycemia and was found to have both hyperinsulinism and growth hormone deficiency. Treatment with both recombinant human growth hormone and diazoxide led to blood glucose normalization. Subsequently, he was found to have a genetic diagnosis of 20p11.22p11.21 deletion. 20p11 deletions have been associated with hypopituitarism, most commonly seen in growth hormone deficiency causing hypoglycemia. This case is one of a few to report hyperinsulinism as a manifestation of this deletion.
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627633-1
    ISSN 2090-651X ; 2090-6501
    ISSN (online) 2090-651X
    ISSN 2090-6501
    DOI 10.1155/2023/8658540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Salivary α-amylase activity and flow rate explain differences in temporal flavor perception in a chewing gum matrix comprising starch-limonene inclusion complexes.

    Goza, Jennifer L / Ziegler, Gregory R / Wee, Josephine / Hayes, John E / Hopfer, Helene

    Food research international (Ottawa, Ont.)

    2022  Volume 158, Page(s) 111573

    Abstract: Starch-guest inclusion complexes (ICs) are a novel, clean-label flavor encapsulation system with the potential to improve stability of aroma volatiles. While amylase has been shown to modulate guest release in vitro, release by sensory perception has not ...

    Abstract Starch-guest inclusion complexes (ICs) are a novel, clean-label flavor encapsulation system with the potential to improve stability of aroma volatiles. While amylase has been shown to modulate guest release in vitro, release by sensory perception has not been evaluated. Here, Temporal Check-All-That-Apply (TCATA) and CATA were used to compare flavor perception of starch-limonene ICs to uncomplexed limonene, and the differences in perception were explored as a function of participant salivary α-amylase activity (sAA) and salivary flow rate (sFR). High sFR levels decreased limonene perception while high sAA increased limonene perception, highlighting the potential influence of these physiological factors on flavor perception of foods. Temporal flavor perception of a chewing gum containing starch-limonene ICs and a second chewing gum containing uncomplexed limonene and corn starch (CTL) was evaluated by 99 untrained consumers who assessed taste, texture, and aroma attributes over 17 min by TCATA and CATA. In addition, participants were segmented into three clusters based on their sAA and sFR, and cluster TCATA curves for each sample and attribute were statistically compared. Overall, participants rated Citrus, Sour and Bitter (p < 0.05) significantly higher for the IC sample and rated Sweet higher for the CTL. For Citrus, Sour, and Bitter, significant differences were observed between the three clusters for the IC chewing gum, while the CTL gum showed no significant differences for these three attributes. We demonstrate that flavor perception of starch-guest ICs varies with participants' salivary α-amylase activity and flow rate. Additionally, TCATA and CATA were found to be well suited to characterize flavor release systems over a long period of time as multiple flavor percepts can be simultaneously tracked.
    MeSH term(s) Chewing Gum ; Humans ; Limonene/chemistry ; Perception ; Salivary alpha-Amylases/chemistry ; Salivary alpha-Amylases/metabolism ; Starch/chemistry
    Chemical Substances Chewing Gum ; Starch (9005-25-8) ; Limonene (9MC3I34447) ; Salivary alpha-Amylases (EC 3.2.1.1)
    Language English
    Publishing date 2022-06-27
    Publishing country Canada
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2022.111573
    Database MEDical Literature Analysis and Retrieval System OnLINE

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