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  1. Article ; Online: Can One Health Policy Help Us Expand an Ethics of Interconnection and Interdependence?

    Meagher, Karen M

    AMA journal of ethics

    2024  Volume 26, Issue 2, Page(s) E162–170

    Abstract: One Health-a holistic approach to health that brings the moral status of animals and environments into consideration-is understood as a "professional imperative," a value-laden obligation that flows from the scope and objectives of professional roles. In ...

    Abstract One Health-a holistic approach to health that brings the moral status of animals and environments into consideration-is understood as a "professional imperative," a value-laden obligation that flows from the scope and objectives of professional roles. In this article, antimicrobial resistance provides a case study to demonstrate the fruitfulness of public health and bioethics collaborations by applying One Health key concepts of interconnection and interdependence. Moving toward an ethics of One Health requires a more nuanced analysis of ecological relationships, including humans' connections to other species as hosts, vectors, domestic companions, meat-eaters' food, and farmers' livelihood.
    MeSH term(s) Humans ; Animals ; Morals ; One Health ; Bioethics ; Health Policy ; Ethics
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 2376-6980
    ISSN (online) 2376-6980
    DOI 10.1001/amajethics.2024.162
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  2. Article ; Online: Bioethics Theory-Building for Public Health.

    Meagher, Karen M

    The American journal of bioethics : AJOB

    2021  Volume 21, Issue 9, Page(s) 53–56

    MeSH term(s) Bioethics ; Ethical Theory ; Humans ; Public Health
    Language English
    Publishing date 2021-08-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2021.1952344
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  3. Article: The New Precision Stewards?

    Meagher, Karen M / Watson, Sara / Suh, Gina A / Virk, Abinash

    Journal of personalized medicine

    2022  Volume 12, Issue 8

    Abstract: The precision health era is likely to reduce and respond to antimicrobial resistance (AMR). Our stewardship and precision efforts share terminology, seeking to deliver the "right drug, at the right dose, at the right time." Already, rapid diagnostic ... ...

    Abstract The precision health era is likely to reduce and respond to antimicrobial resistance (AMR). Our stewardship and precision efforts share terminology, seeking to deliver the "right drug, at the right dose, at the right time." Already, rapid diagnostic testing, phylogenetic surveillance, and real-time outbreak response provide just a few examples of molecular advances we dub "precision stewardship." However, the AMR causal factors range from the molecular to that of global health policy. Mirroring the cross-sectoral nature of AMR science, the research addressing the ethical, legal and social implications (ELSI) of AMR ranges across academic scholarship. As the rise of AMR is accompanied by an escalating sense of its moral and social significance, what is needed is a parallel field of study. In this paper, we offer a gap analysis of this terrain, or an agenda for "the ELSI of precision stewardship." In the first section, we discuss the accomplishments of a multi-decade U.S. national investment in ELSI research attending to the advances in human genetics. In the next section, we provide an overview of distinct ELSI topics pertinent to AMR. The distinctiveness of an ELSI agenda for precision stewardship suggests new opportunities for collaboration to build the stewardship teams of the future.
    Language English
    Publishing date 2022-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm12081308
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  4. Article ; Online: Seeking context for the duty to rescue: contractualism and trust in research institutions.

    Meagher, Karen M

    The American journal of bioethics : AJOB

    2015  Volume 15, Issue 2, Page(s) 18–20

    MeSH term(s) Beneficence ; Duty to Warn/ethics ; Genetic Research/ethics ; Humans ; Incidental Findings ; Moral Obligations ; Rescue Work/ethics ; Social Responsibility ; Social Values
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2014.990170
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  5. Article ; Online: Fostering a prevention mindset for responsible gene editing.

    Meagher, Karen M / Master, Zubin

    Accountability in research

    2019  Volume 26, Issue 4, Page(s) 251–256

    Abstract: In this special issue, we solicited three commentators to discuss issues specific to the responsible conduct of research as it relates to the birth of gene-edited children. We explore the ethics of prevention and its ties to the responsible conduct of ... ...

    Abstract In this special issue, we solicited three commentators to discuss issues specific to the responsible conduct of research as it relates to the birth of gene-edited children. We explore the ethics of prevention and its ties to the responsible conduct of gene-editing research to introduce three commentaries addressing: (1) the relevance of cultural and regulatory context in China, (2) how to actualize calls for greater public engagement, and (3) where we might improve graduate education of genomic researchers.
    MeSH term(s) China ; Ethics, Research ; Gene Editing ; Humans ; Infant ; Infant, Newborn ; Preventive Medicine ; Twins/genetics
    Language English
    Publishing date 2019-05-17
    Publishing country United States
    Document type Editorial ; Introductory Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2069334-5
    ISSN 1545-5815 ; 0898-9621
    ISSN (online) 1545-5815
    ISSN 0898-9621
    DOI 10.1080/08989621.2019.1617140
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  6. Article: Too much of a good thing? Overdiagnosis, or overestimating risk in preventive genomic screening.

    Meagher, Karen M / Berg, Jonathan S

    Personalized medicine

    2018  Volume 15, Issue 5, Page(s) 343–346

    MeSH term(s) Genetic Testing/ethics ; Genetic Testing/trends ; Genomics ; Humans ; Medical Overuse/prevention & control ; Medical Overuse/trends ; Precision Medicine/methods
    Language English
    Publishing date 2018-09-27
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 2299146-3
    ISSN 1744-828X ; 1741-0541
    ISSN (online) 1744-828X
    ISSN 1741-0541
    DOI 10.2217/pme-2018-0041
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    Zs.A 6549: Show issues Location:
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    Zs.MG 73: Show issues

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  7. Article ; Online: The New Precision Stewards?

    Karen M. Meagher / Sara Watson / Gina A. Suh / Abinash Virk

    Journal of Personalized Medicine, Vol 12, Iss 1308, p

    2022  Volume 1308

    Abstract: The precision health era is likely to reduce and respond to antimicrobial resistance (AMR). Our stewardship and precision efforts share terminology, seeking to deliver the “right drug, at the right dose, at the right time.” Already, rapid diagnostic ... ...

    Abstract The precision health era is likely to reduce and respond to antimicrobial resistance (AMR). Our stewardship and precision efforts share terminology, seeking to deliver the “right drug, at the right dose, at the right time.” Already, rapid diagnostic testing, phylogenetic surveillance, and real-time outbreak response provide just a few examples of molecular advances we dub “precision stewardship.” However, the AMR causal factors range from the molecular to that of global health policy. Mirroring the cross-sectoral nature of AMR science, the research addressing the ethical, legal and social implications (ELSI) of AMR ranges across academic scholarship. As the rise of AMR is accompanied by an escalating sense of its moral and social significance, what is needed is a parallel field of study. In this paper, we offer a gap analysis of this terrain, or an agenda for “the ELSI of precision stewardship.” In the first section, we discuss the accomplishments of a multi-decade U.S. national investment in ELSI research attending to the advances in human genetics. In the next section, we provide an overview of distinct ELSI topics pertinent to AMR. The distinctiveness of an ELSI agenda for precision stewardship suggests new opportunities for collaboration to build the stewardship teams of the future.
    Keywords antimicrobial drug resistance ; microbial genetics ; antimicrobial stewardship ; biomedical ethics ; biomedical research ; environment and public health ; Medicine ; R
    Subject code 170
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Bioethics Advocacy in Ethos, Practice and Metrics.

    Barwise, Amelia K / Thorsteinsdottir, Bjoerg / Allyse, Megan A / Clarke, Michelle J / Meagher, Karen M

    The American journal of bioethics : AJOB

    2021  Volume 21, Issue 2, Page(s) 69–72

    MeSH term(s) Benchmarking ; Bioethics ; COVID-19 ; Humans ; Patient Advocacy ; SARS-CoV-2
    Language English
    Publishing date 2021-02-03
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2020.1861373
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  9. Article ; Online: Multiple Marginalizations: What Bioethics Can Learn From Black Feminism.

    Cheema, Amal W / Meagher, Karen M / Sharp, Richard R

    The American journal of bioethics : AJOB

    2019  Volume 19, Issue 2, Page(s) 1–3

    MeSH term(s) African Continental Ancestry Group ; Attitude of Health Personnel ; Bioethics/trends ; Conflict of Interest ; Ethical Theory ; Female ; Feminism ; Humans ; Patient Selection/ethics ; Personal Autonomy ; Social Justice/ethics ; Social Marginalization ; Social Values
    Language English
    Publishing date 2019-02-20
    Publishing country United States
    Document type Editorial
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2019.1575142
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  10. Article ; Online: The Slippery Slope of Prenatal Testing for Social Traits.

    Canter, Courtney / Foley, Kathleen / Callier, Shawneequa L / Meagher, Karen M / Waltz, Margaret / Washington, Aurora / Cadigan, R Jean / Prince, Anya E R

    The American journal of bioethics : AJOB

    2022  Volume 23, Issue 3, Page(s) 36–38

    MeSH term(s) Humans ; Suicide, Assisted/ethics ; Morals ; Sociological Factors
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2023.2169395
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