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  1. Article ; Online: Morphometric study applied to testicular and epididymis hydatids torsion.

    Barbosa, Renato G / Favorito, Luciano Alves / Sampaio, Francisco J B

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 3249

    Abstract: Twisted testicular appendages had difficult differential diagnosis with testicular torsion. The objective of this paper is to evaluate the number, shape, size and determine the laterality pattern of the testicular and epididymal hydatids and evaluate the ...

    Abstract Twisted testicular appendages had difficult differential diagnosis with testicular torsion. The objective of this paper is to evaluate the number, shape, size and determine the laterality pattern of the testicular and epididymal hydatids and evaluate the correlations between the length and width of the testicular and epididymal hydatids with testicular measurements. We analyzed 60 fixed cadavers and 16 patients with prostate cancer without previous hormonal treatment undergoing bilateral orchiectomy, totalizing 76 units and 152 testicles. In relation to the testicular appendices, we analyzed the following situations: absence of testicular and epididymis appendages, presence of a testicular appendix, presence of epididymis appendix, and presence of testicular and epididymis appendix. We measured the length, width and thickness of the testis and classified the appendages as sessile or pedicled. Chi-square test was used to verify associations between categorical variables. McNemar Test was used to verify differences between the percentages of right and left appendages. Correlations between quantitative measures were evaluated using the Pearson Correlation Coefficient (p < 0.05). In 50 cases (65.78%) we observed the presence of some type of appendices, in 34 cases (44.72%) we observed the presence of testicular appendices and in 19 cases (25%) the presence of epididymal appendices. We observed the presence of pedicled appendices in 39 cases (51.32%), with 25 of the cases (32.89%) of pedicled testicular appendices and 14 of the cases (18.42%) of pedicled epididymal appendages, with a significant association between the occurrence of appendices on the right and left sides (p < 0.001). Testicular hydatids were present in around two thirds of our sample being pedunculated in almost half of the cases with bilateral similarity. There is a significant chance in cases of twisted appendices that the same anatomical characteristics are present on the opposite side, which is a factor that tends to indicate the need for contralateral surgical exploration in cases of torsion, however studies with larger samples are needed to confirm these findings.
    MeSH term(s) Male ; Humans ; Testis/surgery ; Epididymis/surgery ; Spermatic Cord Torsion/diagnosis ; Spermatic Cord Torsion/surgery ; Pelvis ; Orchiectomy
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52734-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Kidney collecting system anatomy applied to endourology - a narrative review.

    Morais, Ana Raquel M / Favorito, Luciano A / Sampaio, Francisco J B

    International braz j urol : official journal of the Brazilian Society of Urology

    2024  Volume 50, Issue 2, Page(s) 164–177

    Abstract: Objective: To evaluate the surgical anatomy of the kidney collecting system through a narrative review of the literature, highlighting its importance during diagnosis and its approach during surgical procedures for the treatment of renal stones.: ... ...

    Abstract Objective: To evaluate the surgical anatomy of the kidney collecting system through a narrative review of the literature, highlighting its importance during diagnosis and its approach during surgical procedures for the treatment of renal stones.
    Material and methods: We carried out a review about the anatomy of the kidney collecting system. We analyzed papers published in the past 40 years in the databases Pubmed, Embase and Scielo, and we included only papers in English and excluded case reports, editorials and opinions of specialists.
    Results: Renal collecting system could be divided in four groups: A1 - kidney midzone (KM), drained by minor calyx that are dependent on the superior or the inferior caliceal groups; A2 - KM drained by crossed calyx, one draining into the superior caliceal group and another draining into the inferior caliceal group; B1 - KM drained by a major caliceal group independent of both the superior and inferior groups; and B2 - KM drained by minor calyx entering directly into the renal pelvis. Some details and anatomic variations of the collecting system are related to clinical and radiological aspects, particularly perpendicular calyces, interpyelocalyx space, position of calyces in relation to renal border, classification of the renal collecting system, infundibular diameter and the angle between the lower infundibulum and renal pelvis.
    Conclusion: The knowledge of intra-renal collecting system divisions and variations as the angle between the renal pelvis and lower infundibula, position of the calices in relationship with renal edge and the diameter and position of the calyces are important for the planning of minimally invasive renal surgeries.
    MeSH term(s) Humans ; Kidney/diagnostic imaging ; Kidney/surgery ; Kidney Calices/diagnostic imaging ; Kidney Calices/surgery ; Kidney Pelvis/diagnostic imaging ; Kidney Pelvis/surgery ; Kidney Calculi/diagnostic imaging ; Kidney Calculi/surgery ; Databases, Factual
    Language English
    Publishing date 2024-02-22
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2024.9901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reflections on the COVID-19 Pandemic.

    Sampaio, Francisco J B

    International braz j urol : official journal of the Brazilian Society of Urology

    2020  Volume 46, Issue 4, Page(s) 499–500

    MeSH term(s) COVID-19 ; Coronavirus Infections/epidemiology ; Health Knowledge, Attitudes, Practice ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Urology/trends ; Vulnerable Populations
    Keywords covid19
    Language English
    Publishing date 2020-06-01
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2020.04.02
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Reflections on the COVID-19 Pandemic

    Sampaio, Francisco J. B.

    International braz j urol v.46 n.4 2020

    2020  

    Keywords covid19
    Language English
    Publishing date 2020-08-01
    Publisher Sociedade Brasileira de Urologia
    Publishing country br
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The role of intra-abdominal pressure in human testicular migration.

    Logsdon, Natasha T / Sampaio, Francisco J B / Favorito, Luciano Alves

    International braz j urol : official journal of the Brazilian Society of Urology

    2022  Volume 47, Issue 1, Page(s) 36–44

    Abstract: Objectives: This review aims to study the role of the abdominal wall in testicular migration process during the human fetal period.: Materials and methods: We performed a descriptive review of the literature about the role of the abdominal wall in ... ...

    Abstract Objectives: This review aims to study the role of the abdominal wall in testicular migration process during the human fetal period.
    Materials and methods: We performed a descriptive review of the literature about the role of the abdominal wall in testicular migration during the human fetal period.
    Results: The rise in intra-abdominal pressure is a supporting factor for testicular migration. This process has two phases: the abdominal and the inguinal-scrotal stages. The passage of the testis through the inguinal canal occurs very quickly between 21 and 25 WPC. Bilateral cryptorchidism in Prune Belly syndrome is explained by the impaired contraction of the muscles of the abdominal wall; mechanical obstruction due to bladder distention and structural alteration of the inguinal canal, which hampers the passage of the testis during the inguinoscrotal stage of testicular migration. Abdominal wall defects as gastroschisis and omphaloceles are associated with undescended testes in around 30 to 40% of the cases.
    Conclusions: Abdominal pressure wound is an auxiliary force in testicular migration. Patients with abdominal wall defects are associated with undescendend testis in more than 30% of the cases probably due to mechanical factors; the Prune Belly Syndrome has anatomical changes in the anterior abdominal wall that hinder the increase of intra-abdominal pressure which could be the cause of cryptorchidism in this syndrome.
    MeSH term(s) Cryptorchidism ; Humans ; Inguinal Canal ; Male ; Prune Belly Syndrome ; Scrotum ; Testis
    Language English
    Publishing date 2022-01-12
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2021.99.03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effects of dutasteride and tamsulosin on penile morphology in a rodent model.

    da Silva, Marcello H A / Costa, Waldemar S / Sampaio, Francisco J B / de Souza, Diogo B

    International braz j urol : official journal of the Brazilian Society of Urology

    2023  Volume 49, Issue 3, Page(s) 320–333

    Abstract: Purpose: To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model.: Materials and methods: Forty male rats were assigned into the following groups: Control group (C, receiving ... ...

    Abstract Purpose: To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model.
    Materials and methods: Forty male rats were assigned into the following groups: Control group (C, receiving distilled water, n=10); Dutasteride group (D, receiving 0.5 mg/Kg/day of dutasteride, n=10); Tamsulosin group (T, receiving 0.4 mg/Kg/day of tamsulosin, n=10); and Dutasteride associated with Tamsulosin group (DT, receiving both drugs n = 10). All drugs were administered via oral gavage. After 40 days, the animals were submitted to euthanasia and their penises were collected for histomorphometric analyses. Data were compared using one-way ANOVA followed by Bonferroni's post-test, considering p<0.05 as significant.
    Results: The sinusoidal space and smooth muscle fiber surface densities (Sv), and the cross-sectional penile areas of rats in groups D, T and DT were reduced in comparison to controls with the most notable reductions in the combined therapy group. The connective tissue and elastic system fibers Sv were augmented in groups D, T and DT in comparison with the control group, again with the most pronounced changes observed in animals receiving the combined therapy.
    Conclusion: Both treatments with dutasteride or tamsulosin promoted penile morphometric modifications in a rodent model. The combination therapy resulted in more notable modifications. The results of this study may help to explain the erectile dysfunction observed in some men using these drugs.
    MeSH term(s) Humans ; Male ; Rats ; Animals ; Dutasteride/pharmacology ; Dutasteride/therapeutic use ; Tamsulosin/therapeutic use ; 5-alpha Reductase Inhibitors/therapeutic use ; Prostatic Hyperplasia/drug therapy ; Rodentia ; Cross-Sectional Studies ; Drug Therapy, Combination
    Chemical Substances Dutasteride (O0J6XJN02I) ; Tamsulosin (G3P28OML5I) ; 5-alpha Reductase Inhibitors
    Language English
    Publishing date 2023-04-27
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2022.0583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Effects of comfort food diet on the penile morphology of stressed rats.

    Marchon, Roger G / Gregório, Bianca M / Costa, Waldemar S / Pereira-Sampaio, Marco Aurélio / Sampaio, Francisco J / De Souza, Diogo B

    Heliyon

    2023  Volume 9, Issue 6, Page(s) e17013

    Abstract: Purpose: To investigate the effects of chronic stress, associated or not with comfort food, on the morphology of the penis.: Materials & methods: Thirty-two adult Wistar rats were divided into four experimental groups: Control group (C), receiving ... ...

    Abstract Purpose: To investigate the effects of chronic stress, associated or not with comfort food, on the morphology of the penis.
    Materials & methods: Thirty-two adult Wistar rats were divided into four experimental groups: Control group (C), receiving standard rat chow, and under normal conditions; Stressed group (S), receiving standard chow, and submitted to stressful situations; Control + comfort food group (C + CF), receiving standard chow and comfort food, and under normal conditions; and Stressed + comfort food group (S + CF), receiving standard chow and comfort food, and submitted to stressful situations. At 10 weeks of age, food supply and stress were initiated. All groups had
    Results: Body mass was similar among the groups. Food intake in S + CF group was lower than in other groups. Concerning food preference, groups C + CF and S + CF preferred comfort food over the standard chow, with this preference being higher in S + CF than in C + CF. The area of the corpora cavernosa without tunica albuginea was lower in group S + CF than in group C. Most interestingly, the surface density of connective tissue in the corpora cavernosa was higher in groups S and S + CF compared to group C. In contrast, smooth muscle surface density was markedly lower in S + CF compared to groups C and C + CF, while group S also had reduced smooth muscle in comparison to group C.
    Conclusion: Chronic stress caused a morphological alteration on penile histomorphometry. Also, stress increased the preference for comfort foods which caused more deleterious effects in some parameters.
    Language English
    Publishing date 2023-06-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e17013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of chronic stress on bladder morphology of rats and impact of comfort food diet as an ameliorating agent.

    Marchon, Roger G / Gregório, Bianca M / Pereira-Sampaio, Marco A / Costa, Waldemar S / Sampaio, Francisco J / De Souza, Diogo B

    Stress (Amsterdam, Netherlands)

    2023  Volume 26, Issue 1, Page(s) 2265160

    Abstract: Objectives: To investigate the effects of chronic stress on bladder morphology and the impact of food preference (standard or comfort foods) on the bladder of stressed rats.: Methods: In total, 32 Wistar male rats (3 months old) were divided into ... ...

    Abstract Objectives: To investigate the effects of chronic stress on bladder morphology and the impact of food preference (standard or comfort foods) on the bladder of stressed rats.
    Methods: In total, 32 Wistar male rats (3 months old) were divided into four groups: control (C), stressed (S), control + comfort food (C + CF), and stressed + comfort food (S + CF). Groups C and C + CF were maintained under normal conditions, while groups S and S + CF were subjected to chronic stress by the restraint method. Groups C and S received standard rat chow, while groups C + CF and S + CF received comfort food (Froot Loops®) and standard chow. The stress stimuli were induced daily for 2 h over 8 weeks. After 8 weeks, all animals were killed, and the bladders were removed and used for histomorphometric analysis.
    Results: Body mass was similar among the groups. Stress did not promote differences regarding food intake, but animals receiving comfort food showed higher calories intake (in kcal/Kg) than animals receiving only standard chow. The C + CF and S + CF groups preferred comfort food over the standard chow; this preference was higher in the S + CF than in the C + CF group. The surface density of smooth muscle was reduced in stressed animals, while connective tissue and elastic system fiber content were increased in stressed groups. Further, epithelial height was increased in rats submitted to chronic stress. The surface density of elastic system fibers was decreased by the consumption of comfort food.
    Conclusions: Chronic stress induces morphological modifications on the bladder wall and epithelium. These modifications may be related to lower urinary tract symptoms. Additionally, chronic stress caused a higher preference for comfort food intake which did not ameliorate or aggravate the stress-induced bladder alterations.
    MeSH term(s) Rats ; Male ; Animals ; Eating/physiology ; Rats, Wistar ; Urinary Bladder ; Stress, Psychological ; Energy Intake
    Language English
    Publishing date 2023-10-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1387706-9
    ISSN 1607-8888 ; 1025-3890
    ISSN (online) 1607-8888
    ISSN 1025-3890
    DOI 10.1080/10253890.2023.2265160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Lower pole anatomy of horseshoe kidney and complete ureteral duplication: Anatomic and radiologic study applied to endourology.

    Sobrinho, Sobrinho U L G P / Sampaio, Francisco J B / Favorito, Luciano A

    International braz j urol : official journal of the Brazilian Society of Urology

    2022  Volume 48, Issue 3, Page(s) 561–568

    Abstract: Purpose: To analyze the 3-dimensional intrarenal anatomy of horseshoe kidneys (HK) and kidney with complete ureteral duplication (CUD), in polyester resin endocasts of the collecting system and in patients submitted to 3D computerized tomography scan ( ... ...

    Abstract Purpose: To analyze the 3-dimensional intrarenal anatomy of horseshoe kidneys (HK) and kidney with complete ureteral duplication (CUD), in polyester resin endocasts of the collecting system and in patients submitted to 3D computerized tomography scan (CT-scan).
    Materials and methods: We analyzed seven 3-dimensional polyester resin endocasts of the kidney collecting system obtained from 6 fresh adult cadavers (4 with unilateral CUD and 2 with horseshoe kidney) and CT-scan reconstruction images of kidneys from 24 patients: 6 patients with HK, 8 with CUD and 10 patients without renal anomalies that were used as controls. We analyzed the spatial distribution of the calices, the infundibula diameters, the angle between the lower infundibulum and the renal pelvis (LIP) and the angle between the lower infundibulum and the inferior minor calyces (LIICA). Measurements of the width and length of the inferior infundibulum and the infundibula of the minor calyces, as well as the angles (LIP and LIICA) were made with the aid of the LibreOffice 6.3 software. The data were analyzed with the IBM® SPSS® Statistics.
    Results: There was no statistical difference in the inferior pole measurements between the groups with anomalies and the control group, both in polyester resin endocasts and CT-scan reconstruction images for LIP. When we compared the LIP in the CT-scan between HK versus CUD (p= 0.003), and HK versus the control group (p= 0.035), we observed statistical difference.
    Conclusions: The knowledge of spatial anatomy of lower pole is of utmost importance during endourologic procedures in patients with kidney anomalies. In the present study we observed that horseshoe kidneys had more restrictive anatomic factors in lower pole than the complete ureteral duplication.
    MeSH term(s) Adult ; Fused Kidney/diagnostic imaging ; Humans ; Kidney/anatomy & histology ; Kidney/diagnostic imaging ; Kidney Calculi ; Kidney Calices/diagnostic imaging ; Kidney Pelvis/diagnostic imaging
    Language English
    Publishing date 2022-03-24
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2022.99.12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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