LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 10510

Search options

  1. Article ; Online: Chaperone-mediated autophagy on the clock.

    He, Congcong

    Nature cell biology

    2021  Volume 23, Issue 12, Page(s) 1220–1221

    MeSH term(s) Autophagy ; Chaperone-Mediated Autophagy
    Language English
    Publishing date 2021-12-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1474722-4
    ISSN 1476-4679 ; 1465-7392
    ISSN (online) 1476-4679
    ISSN 1465-7392
    DOI 10.1038/s41556-021-00811-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5169: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 12: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Balancing nutrient and energy demand and supply via autophagy.

    He, Congcong

    Current biology : CB

    2022  Volume 32, Issue 12, Page(s) R684–R696

    Abstract: Maintaining nutrient and energy homeostasis is crucial for the survival and function of cells and organisms in response to environmental stress. Cells have evolved a stress-induced catabolic pathway, termed autophagy, to adapt to stress conditions such ... ...

    Abstract Maintaining nutrient and energy homeostasis is crucial for the survival and function of cells and organisms in response to environmental stress. Cells have evolved a stress-induced catabolic pathway, termed autophagy, to adapt to stress conditions such as starvation. During autophagy, damaged or non-essential cellular structures are broken down in lysosomes, and the resulting metabolites are reused for core biosynthetic processes or energy production. Recent studies have revealed that autophagy can target and degrade different types of nutrient stores and produce a variety of metabolites and fuels, including amino acids, nucleotides, lipids and carbohydrates. Here, we will focus on how autophagy functions to balance cellular nutrient and energy demand and supply - specifically, how energy deprivation switches on autophagic catabolism, how autophagy halts anabolism by degrading the protein synthesis machinery, and how bulk and selective autophagy-derived metabolites recycle and feed into a variety of bioenergetic and anabolic pathways during stress conditions. Recent new insights and progress in these areas provide a better understanding of how resource mobilization and reallocation sustain essential metabolic and anabolic activities under unfavorable conditions.
    MeSH term(s) Autophagy/physiology ; Energy Metabolism ; Humans ; Lysosomes/metabolism ; Nutrients ; Starvation/metabolism
    Language English
    Publishing date 2022-06-20
    Publishing country England
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2022.04.071
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Only zinc (Zn) among micronutrients is an important predictor of grassland production.

    Liu, Congcong / Xu, Meng / Li, Ying / He, Nianpeng

    Frontiers in plant science

    2022  Volume 13, Page(s) 962513

    Language English
    Publishing date 2022-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.962513
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Author Correction: Relationships of stomatal morphology to the environment across plant communities.

    Liu, Congcong / Sack, Lawren / Li, Ying / Zhang, Jiahui / Yu, Kailiang / Zhang, Qiongyu / He, Nianpeng / Yu, Guirui

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 439

    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-44730-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Degradative and Non-Degradative Roles of Autophagy Proteins in Metabolism and Metabolic Diseases

    Kenta Kuramoto / Congcong He

    Frontiers in Cell and Developmental Biology, Vol

    2022  Volume 10

    Abstract: Autophagy is a stress-induced lysosomal degradation pathway regulated by evolutionarily conserved autophagy-related (ATG) genes. Recent research has revealed that autophagy plays an important role in the regulation of energy metabolism, development of ... ...

    Abstract Autophagy is a stress-induced lysosomal degradation pathway regulated by evolutionarily conserved autophagy-related (ATG) genes. Recent research has revealed that autophagy plays an important role in the regulation of energy metabolism, development of metabolic tissues, and pathogenesis of metabolic disorders. Bulk and selective degradation by autophagy helps maintain protein homeostasis and physiological function of cells. Aside from classical degradative roles, ATG proteins also carry out non-classical secretory functions of metabolic tissues. In this review, we summarize recent progresses and unanswered questions on the mechanisms of autophagy and ATG proteins in metabolic regulation, with a focus on organelle and nutrient storage degradation, as well as vesicular and hormonal secretion. Such knowledge broadens our understanding on the cause, pathophysiology, and prevention of metabolic diseases including obesity and diabetes.
    Keywords autophagy-related gene ; mitophagy ; lipophagy ; ER-phagy ; adipose tissue ; liver ; Biology (General) ; QH301-705.5
    Subject code 570
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: The main cause of tibial prosthesis malalignment after total knee arthroplasty in Southern Chinese population.

    He, Lili / Wu, Congcong / Lang, Junzhe / Chen, Lei / Wu, Peng

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e25447

    Abstract: Objectives: This study aimed to determine the occurrence rate of malalignment of tibial prosthesis and explore the influencing factors.: Methods: 296 patients from Southern China who underwent total knee arthroplasty (TKA) were selected as the ... ...

    Abstract Objectives: This study aimed to determine the occurrence rate of malalignment of tibial prosthesis and explore the influencing factors.
    Methods: 296 patients from Southern China who underwent total knee arthroplasty (TKA) were selected as the research objects. Their general demographic data were recorded. The tibial bowing angle (TBA), tibial length, medial proximal tibial angle (MPTA), tibial plateau shift angle (TPSA), tibial bone loss, lateral distal tibial angle, and overall width of tibial plateau and widths of medial and lateral tibial plateau were measured before TKA. The tibial component coronal alignment angle (TCCA) was measured after the operation. Malalignment of the tibial prosthesis was defined as TCCA <87° or TCCA >93°. Tibial bowing was indicated by TBA >2°, and lateral bowing was recorded as +. The correlations of TCCA with demographic data and pre-operation imaging measurement parameters were statistically analyzed.
    Results: Bivariate correlation analysis revealed negative correlations between TCCA and TBA (r = -0.602, P < 0.001) and TPSA (r = -0.304, P < 0.001), and a positive correlation with MPTA (r = -0.318, P < 0.001). Multivariate linear regression analysis demonstrated a significant negative correlation between TCCA and TBA (P < 0.001). The occurrence rate of malalignment of tibial prosthesis was 12.37 %. The occurrence rates of malalignment were 22.54 % in the tibial bowing group and 6.87 % in the non-tibial bowing group, showing statistical differences (P < 0.001).
    Conclusion: The malalignment rate of tibial prosthesis among Southern Chinese patients is relatively high, possibly attributed to the tibial anatomy anomalies, particularly the tibial bowing. The entry point should be determined based on tibial morphology.
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25447
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Degradative and Non-Degradative Roles of Autophagy Proteins in Metabolism and Metabolic Diseases.

    Kuramoto, Kenta / He, Congcong

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 844481

    Abstract: Autophagy is a stress-induced lysosomal degradation pathway regulated by evolutionarily conserved autophagy-related (ATG) genes. Recent research has revealed that autophagy plays an important role in the regulation of energy metabolism, development of ... ...

    Abstract Autophagy is a stress-induced lysosomal degradation pathway regulated by evolutionarily conserved autophagy-related (ATG) genes. Recent research has revealed that autophagy plays an important role in the regulation of energy metabolism, development of metabolic tissues, and pathogenesis of metabolic disorders. Bulk and selective degradation by autophagy helps maintain protein homeostasis and physiological function of cells. Aside from classical degradative roles, ATG proteins also carry out non-classical secretory functions of metabolic tissues. In this review, we summarize recent progresses and unanswered questions on the mechanisms of autophagy and ATG proteins in metabolic regulation, with a focus on organelle and nutrient storage degradation, as well as vesicular and hormonal secretion. Such knowledge broadens our understanding on the cause, pathophysiology, and prevention of metabolic diseases including obesity and diabetes.
    Language English
    Publishing date 2022-05-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.844481
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Study of noise and structural characteristics of twin-screw air compressor based on multi-physical field coupling

    Yayin He / Congcong Xiao / Wei Zhang / Kai Wang

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 12

    Abstract: Abstract For the problems of high noise and low efficiency of twin-screw air compressor, the mutual coupling effect of noise and structure for the twin-screw air compressor is studied by using acoustic-solid coupling technology. The simulation model of ... ...

    Abstract Abstract For the problems of high noise and low efficiency of twin-screw air compressor, the mutual coupling effect of noise and structure for the twin-screw air compressor is studied by using acoustic-solid coupling technology. The simulation model of acoustic-structural coupling of twin-screw air compressor is established. Combining acoustic wave theory calculation with structural characteristics, the sound pressure level distribution and structural deformation law of different tangent planes of the shell at different frequencies under external excitation are studied. The results show that when the frequency is different, the more intensive the acceleration distribution on the shell surface is, the greater the sound pressure level is. At the same frequency, as the incident pressure wave increases, the deformation on the shell also increases, and the maximum shell deformation and the maximum sound pressure level both appear around 2000 Hz. As the frequency increases, the acceleration distribution on the surface of the shell becomes more denser and the sound pressure level becomes larger.
    Keywords Medicine ; R ; Science ; Q
    Subject code 620
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Study of noise and structural characteristics of twin-screw air compressor based on multi-physical field coupling.

    He, Yayin / Xiao, Congcong / Zhang, Wei / Wang, Kai

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 20879

    Abstract: For the problems of high noise and low efficiency of twin-screw air compressor, the mutual coupling effect of noise and structure for the twin-screw air compressor is studied by using acoustic-solid coupling technology. The simulation model of acoustic- ... ...

    Abstract For the problems of high noise and low efficiency of twin-screw air compressor, the mutual coupling effect of noise and structure for the twin-screw air compressor is studied by using acoustic-solid coupling technology. The simulation model of acoustic-structural coupling of twin-screw air compressor is established. Combining acoustic wave theory calculation with structural characteristics, the sound pressure level distribution and structural deformation law of different tangent planes of the shell at different frequencies under external excitation are studied. The results show that when the frequency is different, the more intensive the acceleration distribution on the shell surface is, the greater the sound pressure level is. At the same frequency, as the incident pressure wave increases, the deformation on the shell also increases, and the maximum shell deformation and the maximum sound pressure level both appear around 2000 Hz. As the frequency increases, the acceleration distribution on the surface of the shell becomes more denser and the sound pressure level becomes larger.
    Language English
    Publishing date 2023-11-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-48362-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Author Correction

    Congcong Liu / Lawren Sack / Ying Li / Jiahui Zhang / Kailiang Yu / Qiongyu Zhang / Nianpeng He / Guirui Yu

    Nature Communications, Vol 15, Iss 1, Pp 1-

    Relationships of stomatal morphology to the environment across plant communities

    2024  Volume 1

    Keywords Science ; Q
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top