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  1. Book ; Online: Hormone Action and Signal Transduction in Endocrine Physiology and Disease

    Hunyady, László / Balla, Tamas

    2020  

    Keywords Medicine ; Endocrinology ; signal transduction ; ACTH ; G protein ; beta-arrestin ; sertolli cells ; gonadotroph cell ; myometrium contractility ; TSH receptor
    Size 1 electronic resource (134 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230645
    ISBN 9782889661008 ; 2889661008
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Phosphoinositides / 2

    Balla, Tamas

    (Subcellular biochemistry ; 59)

    2012  

    Author's details Tama Balla ... ed
    Series title Subcellular biochemistry ; 59
    Phosphoinositides
    Collection Phosphoinositides
    Language English
    Size XV, 460 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017180567
    ISBN 978-94-007-3014-4 ; 9789400730151 ; 94-007-3014-4 ; 9400730152
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Phosphoinositides / 1

    Balla, Tamas

    (Subcellular biochemistry ; 58)

    2012  

    Author's details Tama Balla ... ed
    Series title Subcellular biochemistry ; 58
    Phosphoinositides
    Collection Phosphoinositides
    Keywords Phosphoinositides
    Subject code 572.57
    Language English
    Size XV, 352 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017198601
    ISBN 978-94-007-3011-3 ; 94-007-3011-X ; 9789400730120 ; 9400730128
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Rushing to maintain plasma membrane phosphoinositide levels.

    Balla, Tamas

    The Journal of general physiology

    2020  Volume 152, Issue 12

    MeSH term(s) 1-Phosphatidylinositol 4-Kinase ; Cell Membrane ; Phosphatidylinositol Phosphates ; Phosphatidylinositols
    Chemical Substances Phosphatidylinositol Phosphates ; Phosphatidylinositols ; 1-Phosphatidylinositol 4-Kinase (EC 2.7.1.67)
    Language English
    Publishing date 2020-11-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3118-5
    ISSN 1540-7748 ; 0022-1295
    ISSN (online) 1540-7748
    ISSN 0022-1295
    DOI 10.1085/jgp.202012793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: PI(4,5)P2-dependent and -independent roles of PI4P in the control of hormone secretion by pituitary cells.

    Stojilkovic, Stanko S / Balla, Tamas

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1118744

    Abstract: Plasma membrane and organelle membranes are home to seven phosphoinositides, an important class of low-abundance anionic signaling lipids that contribute to cellular functions by recruiting cytoplasmic proteins or interacting with the cytoplasmic domains ...

    Abstract Plasma membrane and organelle membranes are home to seven phosphoinositides, an important class of low-abundance anionic signaling lipids that contribute to cellular functions by recruiting cytoplasmic proteins or interacting with the cytoplasmic domains of membrane proteins. Here, we briefly review the functions of three phosphoinositides, PI4P, PI(4,5)P2, and PI(3,4,5)P3, in cellular signaling and exocytosis, focusing on hormone-producing pituitary cells. PI(4,5)P2, acting as a substrate for phospholipase C, plays a key role in the control of pituitary cell functions, including hormone synthesis and secretion. PI(4,5)P2 also acts as a substrate for class I PI3-kinases, leading to the generation of two intracellular messengers, PI(3,4,5)P3 and PI(3,4)P2, which act through their intracellular effectors, including Akt. PI(4,5)P2 can also influence the release of pituitary hormones acting as an intact lipid to regulate ion channel gating and concomitant calcium signaling, as well as the exocytic pathway. Recent findings also show that PI4P is not only a precursor of PI(4,5)P2, but also a key signaling molecule in many cell types, including pituitary cells, where it controls hormone secretion in a PI(4,5)P2-independent manner.
    MeSH term(s) Phosphatidylinositols/metabolism ; Signal Transduction/physiology ; Cell Membrane/metabolism ; Biological Transport ; Hormones/metabolism
    Chemical Substances Phosphatidylinositols ; Hormones
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Intramural
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1118744
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evaluation of groundwater quality in the rural environment using geostatistical analysis and WebGIS methods in a Hungarian settlement, Báránd.

    Balla, Dániel / Kiss, Emőke / Zichar, Marianna / Mester, Tamás

    Environmental science and pollution research international

    2023  

    Abstract: The evaluation, visualization of environmental data from long-term monitoring, and making them accessible in a processed form in user-friendly interfaces on the Internet are important tasks of our time. The pollution of groundwater resources in ... ...

    Abstract The evaluation, visualization of environmental data from long-term monitoring, and making them accessible in a processed form in user-friendly interfaces on the Internet are important tasks of our time. The pollution of groundwater resources in settlements is a global phenomenon, the mitigation of which requires a number of environmental measures. In this study, water quality changes following the construction of a sewerage network were examined in the course of long-term monitoring between 2013 and 2022, during which 40 municipal groundwater wells were regularly sampled. Classifying the monitoring data into pollution categories based on water quality index (WQI) and degree of contamination index (Cd), a high degree of contamination was found in the period before the installation of the sewerage network (2014), as the majority of the wells were classified as contaminated and heavily contaminated. In the monitoring period following the installation of the sewerage network, a significant positive change was found in the case of most of the water chemical parameters tested (EC, NH
    Language English
    Publishing date 2023-07-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28627-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ca

    Balla, Tamas

    The Journal of physiology

    2018  Volume 596, Issue 14, Page(s) 2709–2716

    Abstract: Discovery of the STIM1 and Orai proteins as the principal components of store-operated ... ...

    Abstract Discovery of the STIM1 and Orai proteins as the principal components of store-operated Ca
    MeSH term(s) Calcium/metabolism ; Cell Membrane/metabolism ; Endoplasmic Reticulum/metabolism ; Humans ; Lipids ; Membrane Proteins/metabolism
    Chemical Substances Lipids ; Membrane Proteins ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2018-01-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP274957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Korábban SARS-CoV-2-fertőzésen átesett betegek műtéti érzéstelenítése és perioperatív ellátása.

    Balla, Boglárka / Fülesdi, Béla / Végh, Tamás

    Orvosi hetilap

    2022  Volume 163, Issue 18, Page(s) 695–701

    Abstract: Összefoglaló. A korábban SARS-CoV-2-vírusfertőzésen átesett betegeknél különösen fontos az elektív műtét időpontjának megválasztása. Egy több, mint százezer beteget felölelő tanulmány szerint átlagosan 7 hét szükséges az elektív műtétre bocsátáshoz. ... ...

    Abstract Összefoglaló. A korábban SARS-CoV-2-vírusfertőzésen átesett betegeknél különösen fontos az elektív műtét időpontjának megválasztása. Egy több, mint százezer beteget felölelő tanulmány szerint átlagosan 7 hét szükséges az elektív műtétre bocsátáshoz. Sürgős műtétek esetében a beteg általános állapota és a műtéttől várt javulás alapján mérlegelendő a műtét időpontja. A vitális indikációjú műtétek képezik a legnagyobb rizikót, hiszen ezen esetekben igen csekély idő és lehetőség van a preoperatív betegelőkészítésre. A SARS-CoV-2-vírusfertőzés nem minden esetben múlik el nyomtalanul. Szövődményeként felléphetnek cardiopulmonalis, véralvadási, központi idegrendszeri, mozgásszervi problémák, akut veseelégtelenség, ion- és vércukorháztartás felborulása, valamint gastrointestinalis eltérések is, melyek lehetnek rövid vagy hosszú távúak, illetve egyes esetekben maradandó károsodások is. A preoperatív kivizsgálási stratégiát, a műtéti érzéstelenítés módszerét (általános vagy regionális), valamint az intraoperatív monitorozást ezen szövődmények súlyosságának, valamint a műtét típusához megfelelően kell megválasztani. A posztoperatív időszakban a SARS-CoV-2-vírusfertőzésen átesett betegek körében gyakrabban lehet szükség emelt szintű monitorozásra vagy intenzív osztályos megfigyelésre. Orv Hetil. 2022; 163(18): 695-701. Summary. The timing of elective surgery is very important in patients, who suffered SARS-CoV-2 virus infection. According to a study of more than 100,000 patients, it takes approximately seven weeks to be safely admitted to elective surgery. In the case of emergency surgeries, the date of the surgery should be considered based on the patient's general condition and the expected improvement from the surgery. Surgery with a vital indication takes the greatest risk, as there is very little time and opportunity for preoperative examination in these cases. SARS-CoV-2 virus infection does not go away without a trace. Complications may include cardiopulmonary, coagulation, central nervous system, locomotor problems, acute renal failure, ionic and diabetic disorders, and gastrointestinal abnormalities, which may be short-term or long-term, and in some cases permanent. The preoperative examination strategy, the method of anesthesia (general or regional) and the intraoperative monitoring should be chosen according to the severity of these complications and the type of surgery. In the postoperative period, patients suffered with SARS-CoV-2 virus infection may require more frequent monitoring or intensive ward monitoring. Orv Hetil. 2022; 163(18): 695-701.
    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-05-01
    Publishing country Hungary
    Document type Journal Article
    ZDB-ID 123879-6
    ISSN 1788-6120 ; 0030-6002
    ISSN (online) 1788-6120
    ISSN 0030-6002
    DOI 10.1556/650.2022.32506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cell biology: Lipid code for membrane recycling.

    Balla, Tamas

    Nature

    2016  Volume 529, Issue 7586, Page(s) 292–293

    MeSH term(s) Endosomes/metabolism ; Exocytosis ; Humans ; Phosphatidylinositol Phosphates/metabolism ; Phosphatidylinositols/metabolism
    Chemical Substances Phosphatidylinositol Phosphates ; Phosphatidylinositols
    Language English
    Publishing date 2016-01-21
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/nature16868
    Database MEDical Literature Analysis and Retrieval System OnLINE

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