LIVIVO - Search results -

Search results

Result 1 - 10 of total 2549

Search options

Article: High-throughput screen with the l,d-transpeptidase Ldt

de Munnik, Mariska / Lang, Pauline A / De Dios Anton, Francisco / Cacho, Mónica / Bates, Robert H / Brem, Jürgen / Rodríguez Miquel, Beatriz / Schofield, Christopher J

Chemical science

2023 Volume 14, Issue 26, Page(s) 7262–7278

Abstract: Disruption of bacterial cell wall biosynthesis ... ...

Abstract	Disruption of bacterial cell wall biosynthesis in
Language	English
Publishing date	2023-05-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2559110-1
ISSN	2041-6539 ; 2041-6520
ISSN (online)	2041-6539
ISSN	2041-6520
DOI	10.1039/d2sc06858c
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Different feedstocks of biochar affected the bioavailability and uptake of heavy metals by wheat (Triticum aestivum L.) plants grown in metal contaminated soil.

Amin, Muhammad Ahmar / Haider, Ghulam / Rizwan, Muhammad / Schofield, H Kate / Qayyum, Muhammad Farooq / Zia-Ur-Rehman, Muhammad / Ali, Shafaqat

Environmental research

2022 Volume 217, Page(s) 114845

Abstract: ... by wheat (Triticum aestivum L.) plants. The BC was produced from seven different feedstocks (cotton stalks ...

Abstract	Heavy metals (HMs) contamination of agricultural soils is an emerging food safety challenge at world level. Therefore, as a possible treatment for the remediation of a HMs contaminated soil (sewage water irrigation for 20-years), the impact of biochar (BC) was investigated on the uptake of HMs by wheat (Triticum aestivum L.) plants. The BC was produced from seven different feedstocks (cotton stalks (CSBC), rice straw (RSBC), poultry manure (PMBC), lawn grass (LGBC), vegetable peels (VPBC), maize straw (MSBC), and rice husks (RHBC)). Each BC was applied at 1.25% (dry weight basis, w/w) in contaminated soil and a control was maintained without BC addition and wheat was grown in potted soil and harvested at maturity. Results revealed that the properties of different biochars regulated their effects on soil nutrient and HMs mobility and uptake by plants. The maximum plant phosphorous and potassium uptake and translocation to grain (173.4% and 341%, respectively) was found in RSBC treatment over control. The RHBC, PMBC, and MSBC treatments showed a maximum decrease in grain Cd concentration (32.9%, 33.8%, and 34.1%, respectively) compared to the control. The grain Pb (-41% to -51%, with no significant differences among different treatments) and Ni (-63%) concentrations were also reduced significantly following BC treatments compared to control. The daily intake and health risk index of Cd were significantly decreased due to PMBC (-28.1% and -33.8%, respectively), and MSBC (-28.3% and -34.1%, respectively) treatment over control. The BC treatments significantly increased the translocation factor of Cd in the order of VPBC (52.1%) > LGBC (25.4%) > CSBC (13.6%) > RSBC (12.1%) compared to control. The study demonstrated that the effects of BC on metal uptake in plants varied with feedstocks and suitable BC can be further exploited for the rehabilitation of contaminated soils and thereby ensuring food safety.
MeSH term(s)	Soil ; Cadmium/analysis ; Triticum ; Biological Availability ; Soil Pollutants/analysis ; Metals, Heavy ; Edible Grain/chemistry
Chemical Substances	biochar ; Soil ; Cadmium (00BH33GNGH) ; Soil Pollutants ; Metals, Heavy
Language	English
Publishing date	2022-11-21
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.114845
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 726: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Non-Hydrolytic β-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine β-Lactamase Cysteine Variants.

Lohans, Christopher T / Chan, H T Henry / Malla, Tika R / Kumar, Kiran / Kamps, Jos J A G / McArdle, Darius J B / van Groesen, Emma / de Munnik, Mariska / Tooke, Catherine L / Spencer, James / Paton, Robert S / Brem, Jürgen / Schofield, Christopher J

Angewandte Chemie (International ed. in English)

2019 Volume 58, Issue 7, Page(s) 1990–1994

Abstract: ... penicillin-binding proteins) employ a nucleophilic serine, l,d-transpeptidases use a nucleophilic cysteine. The covalent ... complexes formed by l,d-transpeptidases with some β-lactam antibiotics undergo non-hydrolytic fragmentation ... lactams via a similar mechanism as the l,d-transpeptidases, implying the different reaction outcomes are ...

Abstract	Enzymes often use nucleophilic serine, threonine, and cysteine residues to achieve the same type of reaction; the underlying reasons for this are not understood. While bacterial d,d-transpeptidases (penicillin-binding proteins) employ a nucleophilic serine, l,d-transpeptidases use a nucleophilic cysteine. The covalent complexes formed by l,d-transpeptidases with some β-lactam antibiotics undergo non-hydrolytic fragmentation. This is not usually observed for penicillin-binding proteins, or for the related serine β-lactamases. Replacement of the nucleophilic serine of serine β-lactamases with cysteine yields enzymes which fragment β-lactams via a similar mechanism as the l,d-transpeptidases, implying the different reaction outcomes are principally due to the formation of thioester versus ester intermediates. The results highlight fundamental differences in the reactivity of nucleophilic serine and cysteine enzymes, and imply new possibilities for the inhibition of nucleophilic enzymes.
MeSH term(s)	Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/metabolism ; Cysteine/chemistry ; Cysteine/metabolism ; Molecular Conformation ; Peptidyl Transferases/chemistry ; Peptidyl Transferases/metabolism ; beta-Lactamases/chemistry ; beta-Lactamases/metabolism ; beta-Lactams/chemistry ; beta-Lactams/metabolism
Chemical Substances	Anti-Bacterial Agents ; beta-Lactams ; Peptidyl Transferases (EC 2.3.2.12) ; beta-Lactamases (EC 3.5.2.6) ; Cysteine (K848JZ4886)
Language	English
Publishing date	2019-01-21
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2011836-3
ISSN	1521-3773 ; 1433-7851
ISSN (online)	1521-3773
ISSN	1433-7851
DOI	10.1002/anie.201809424
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Improved limits on the lepton-flavor violating decays tau{-}-->l{-}l{+}l{-}.

Aubert, B / Bona, M / Boutigny, D / Karyotakis, Y / Lees, J P / Poireau, V / Prudent, X / Tisserand, V / Zghiche, A / Garra Tico, J / Grauges, E / Lopez, L / Palano, A / Pappagallo, M / Eigen, G / Stugu, B / Sun, L / Abrams, G S / Battaglia, M /

Brown, D N / Button-Shafer, J / Cahn, R N / Groysman, Y / Jacobsen, R G / Kadyk, J A / Kerth, L T / Kolomensky, Yu G / Kukartsev, G / Lopes Pegna, D / Lynch, G / Mir, L M / Orimoto, T J / Osipenkov, I L / Ronan, M T / Tackmann, K / Tanabe, T / Wenzel, W A / Del Amo Sanchez, P / Hawkes, C M / Watson, A T / Koch, H / Schroeder, T / Walker, D / Asgeirsson, D J / Cuhadar-Donszelmann, T / Fulsom, B G / Hearty, C / Mattison, T S / McKenna, J A / Barrett, M / Khan, A / Saleem, M / Teodorescu, L / Blinov, V E / Bukin, A D / Druzhinin, V P / Golubev, V B / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Todyshev, K Yu / Bondioli, M / Curry, S / Eschrich, I / Kirkby, D / Lankford, A J / Lund, P / Mandelkern, M / Martin, E C / Stoker, D P / Abachi, S / Buchanan, C / Foulkes, S D / Gary, J W / Liu, F / Long, O / Shen, B C / Vitug, G M / Zhang, L / Paar, H P / Rahatlou, S / Sharma, V / Berryhill, J W / Campagnari, C / Cunha, A / Dahmes, B / Hong, T M / Kovalskyi, D / Richman, J D / Beck, T W / Eisner, A M / Flacco, C J / Heusch, C A / Kroseberg, J / Lockman, W S / Schalk, T / Schumm, B A / Seiden, A / Wilson, M G / Winstrom, L O / Chen, E / Cheng, C H / Fang, F / Hitlin, D G / Narsky, I / Piatenko, T / Porter, F C / Andreassen, R / Mancinelli, G / Meadows, B T / Mishra, K / Sokoloff, M D / Blanc, F / Bloom, P C / Chen, S / Ford, W T / Hirschauer, J F / Kreisel, A / Nagel, M / Nauenberg, U / Olivas, A / Smith, J G / Ulmer, K A / Wagner, S R / Zhang, J / Gabareen, A M / Soffer, A / Toki, W H / Wilson, R J / Winklmeier, F / Altenburg, D D / Feltresi, E / Hauke, A / Jasper, H / Merkel, J / Petzold, A / Spaan, B / Wacker, K / Klose, V / Kobel, M J / Lacker, H M / Mader, W F / Nogowski, R / Schubert, J / Schubert, K R / Schwierz, R / Sundermann, J E / Volk, A / Bernard, D / Bonneaud, G R / Latour, E / Lombardo, V / Thiebaux, Ch / Verderi, M / Clark, P J / Gradl, W / Muheim, F / Playfer, S / Robertson, A I / Watson, J E / Xie, Y / Andreotti, M / Bettoni, D / Bozzi, C / Calabrese, R / Cecchi, A / Cibinetto, G / Franchini, P / Luppi, E / Negrini, M / Petrella, A / Piemontese, L / Prencipe, E / Santoro, V / Anulli, F / Baldini-Ferroli, R / Calcaterra, A / de Sangro, R / Finocchiaro, G / Pacetti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rama, M / Zallo, A / Buzzo, A / Contri, R / Lo Vetere, M / Macri, M M / Monge, M R / Passaggio, S / Patrignani, C / Robutti, E / Santroni, A / Tosi, S / Chaisanguanthum, K S / Morii, M / Wu, J / Dubitzky, R S / Marks, J / Schenk, S / Uwer, U / Bard, D J / Dauncey, P D / Flack, R L / Nash, J A / Panduro Vazquez, W / Tibbetts, M / Behera, P K / Chai, X / Charles, M J / Mallik, U / Cochran, J / Crawley, H B / Dong, L / Eyges, V / Meyer, W T / Prell, S / Rosenberg, E I / Rubin, A E / Gao, Y Y / Gritsan, A V / Guo, Z J / Lae, C K / Denig, A G / Fritsch, M / Schott, G / Arnaud, N / Béquilleux, J / D'Orazio, A / Davier, M / Grosdidier, G / Höcker, A / Lepeltier, V / Le Diberder, F / Lutz, A M / Pruvot, S / Rodier, S / Roudeau, P / Schune, M H / Serrano, J / Sordini, V / Stocchi, A / Wang, W F / Wormser, G / Lange, D J / Wright, D M / Bingham, I / Burke, J P / Chavez, C A / Fry, J R / Gabathuler, E / Gamet, R / Hutchcroft, D E / Payne, D J / Schofield, K C / Touramanis, C / Bevan, A J / George, K A / Di Lodovico, F / Sacco, R / Cowan, G / Flaecher, H U / Hopkins, D A / Paramesvaran, S / Salvatore, F / Wren, A C / Davis, C L / Allison, J / Bailey, D / Barlow, N R / Barlow, R J / Chia, Y M / Edgar, C L / Lafferty, G D / West, T J / Yi, J I / Anderson, J / Chen, C / Jawahery, A / Roberts, D A / Simi, G / Tuggle, J M / Blaylock, G / Dallapiccola, C / Hertzbach, S S / Li, X / Moore, T B / Salvati, E / Saremi, S / Cowan, R / Dujmic, D / Fisher, P H / Koeneke, K / Sciolla, G / Spitznagel, M / Taylor, F / Yamamoto, R K / Zhao, M / Zheng, Y / McLachlin, S E / Patel, P M / Robertson, S H / Lazzaro, A / Palombo, F / Bauer, J M / Cremaldi, L / Eschenburg, V / Godang, R / Kroeger, R / Sanders, D A / Summers, D J / Zhao, H W / Brunet, S / Côté, D / Simard, M / Taras, P / Viaud, F B / Nicholson, H / De Nardo, G / Fabozzi, F / Lista, L / Monorchio, D / Sciacca, C / Baak, M A / Raven, G / Snoek, H L / Jessop, C P / Knoepfel, K J / Losecco, J M / Benelli, G / Corwin, L A / Honscheid, K / Kagan, H / Kass, R / Morris, J P / Rahimi, A M / Regensburger, J J / Sekula, S J / Wong, Q K / Blount, N L / Brau, J / Frey, R / Igonkina, O / Kolb, J A / Lu, M / Rahmat, R / Sinev, N B / Strom, D / Strube, J / Torrence, E / Gagliardi, N / Gaz, A / Margoni, M / Morandin, M / Pompili, A / Posocco, M / Rotondo, M / Simonetto, F / Stroili, R / Voci, C / Ben-Haim, E / Briand, H / Calderini, G / Chauveau, J / David, P / Del Buono, L / de la Vaissière, Ch / Hamon, O / Leruste, Ph / Malclès, J / Ocariz, J / Perez, A / Prendki, J / Gladney, L / Biasini, M / Covarelli, R / Manoni, E / Angelini, C / Batignani, G / Bettarini, S / Carpinelli, M / Cenci, R / Cervelli, A / Forti, F / Giorgi, M A / Lusiani, A / Marchiori, G / Mazur, M A / Morganti, M / Neri, N / Paoloni, E / Rizzo, G / Walsh, J J / Biesiada, J / Elmer, P / Lau, Y P / Lu, C / Olsen, J / Smith, A J S / Telnov, A V / Baracchini, E / Bellini, F / Cavoto, G / Del Re, D / Di Marco, E / Faccini, R / Ferrarotto, F / Ferroni, F / Gaspero, M / Jackson, P D / Li Gioi, L / Mazzoni, M A / Morganti, S / Piredda, G / Polci, F / Renga, F / Voena, C / Ebert, M / Hartmann, T / Schröder, H / Waldi, R / Adye, T / Castelli, G / Franek, B / Olaiya, E O / Roethel, W / Wilson, F F / Emery, S / Escalier, M / Gaidot, A / Ganzhur, S F / Hamel de Monchenault, G / Kozanecki, W / Vasseur, G / Yèche, Ch / Zito, M / Chen, X R / Liu, H / Park, W / Purohit, M V / White, R M / Wilson, J R / Allen, M T / Aston, D / Bartoldus, R / Bechtle, P / Claus, R / Coleman, J P / Convery, M R / Dingfelder, J C / Dorfan, J / Dubois-Felsmann, G P / Dunwoodie, W / Field, R C / Glanzman, T / Gowdy, S J / Graham, M T / Grenier, P / Hast, C / Innes, W R / Kaminski, J / Kelsey, M H / Kim, H / Kim, P / Kocian, M L / Leith, D W G S / Li, S / Luitz, S / Luth, V / Lynch, H L / Macfarlane, D B / Marsiske, H / Messner, R / Muller, D R / O'Grady, C P / Ofte, I / Perazzo, A / Perl, M / Pulliam, T / Ratcliff, B N / Roodman, A / Salnikov, A A / Schindler, R H / Schwiening, J / Snyder, A / Su, D / Sullivan, M K / Suzuki, K / Swain, S K / Thompson, J M / Va'vra, J / Wagner, A P / Weaver, M / Wisniewski, W J / Wittgen, M / Wright, D H / Yarritu, A K / Yi, K / Young, C C / Ziegler, V / Burchat, P R / Edwards, A J / Majewski, S A / Miyashita, T S / Petersen, B A / Wilden, L / Ahmed, S / Alam, M S / Bula, R / Ernst, J A / Jain, V / Pan, B / Saeed, M A / Wappler, F R / Zain, S B / Krishnamurthy, M / Spanier, S M / Eckmann, R / Ritchie, J L / Ruland, A M / Schilling, C J / Schwitters, R F / Izen, J M / Lou, X C / Ye, S / Bianchi, F / Gallo, F / Gamba, D / Pelliccioni, M / Bomben, M / Bosisio, L / Cartaro, C / Cossutti, F / Della Ricca, G / Lanceri, L / Vitale, L / Azzolini, V / Lopez-March, N / Martinez-Vidal, F / Milanes, D A / Oyanguren, A / Albert, J / Banerjee, Sw / Bhuyan, B / Hamano, K / Kowalewski, R / Nugent, I M / Roney, J M / Sobie, R J / Harrison, P F / Ilic, J / Latham, T E / Mohanty, G B / Band, H R / Chen, X / Dasu, S / Flood, K T / Hollar, J J / Kutter, P E / Pan, Y / Pierini, M / Prepost, R / Wu, S L / Neal, H

Physical review letters

2007 Volume 99, Issue 25, Page(s) 251803

Abstract: A search for the neutrinoless, lepton-flavor violating decay of the tau lepton into three charged leptons has been performed using 376 fb{-1} of data collected at an e{+}e{-} center-of-mass energy around 10.58 GeV with the BABAR detector at the SLAC PEP- ... ...

Abstract	A search for the neutrinoless, lepton-flavor violating decay of the tau lepton into three charged leptons has been performed using 376 fb{-1} of data collected at an e{+}e{-} center-of-mass energy around 10.58 GeV with the BABAR detector at the SLAC PEP-II storage rings. In all six decay modes considered, the numbers of events found in data are compatible with the background expectations. Upper limits on the branching fractions are set in the range (4-8)x10{-8} at 90% confidence level.
Language	English
Publishing date	2007-12-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.99.251803
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 58/153: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Search for lepton flavor violating decays tau(+/-) --> l(+/-)pi0, l(+/-)eta, l(+/-)eta'.

Aubert, B / Bona, M / Boutigny, D / Couderc, F / Karyotakis, Y / Lees, J P / Poireau, V / Tisserand, V / Zghiche, A / Grauges, E / Palano, A / Chen, J C / Qi, N D / Rong, G / Wang, P / Zhu, Y S / Eigen, G / Ofte, I / Stugu, B /

Abrams, G S / Battaglia, M / Brown, D N / Button-Shafer, J / Cahn, R N / Charles, E / Gill, M S / Groysman, Y / Jacobsen, R G / Kadyk, J A / Kerth, L T / Kolomensky, Yu G / Kukartsev, G / Lopes Pegna, D / Lynch, G / Mir, L M / Orimoto, T J / Pripstein, M / Roe, N A / Ronan, M T / Wenzel, W A / Del Amo Sanchez, P / Barrett, M / Ford, K E / Harrison, T J / Hart, A J / Hawkes, C M / Watson, A T / Held, T / Koch, H / Lewandowski, B / Pelizaeus, M / Peters, K / Schroeder, T / Steinke, M / Boyd, J T / Burke, J P / Cottingham, W N / Walker, D / Asgeirsson, D J / Cuhadar-Donszelmann, T / Fulsom, B G / Hearty, C / Knecht, N S / Mattison, T S / McKenna, J A / Khan, A / Kyberd, P / Saleem, M / Sherwood, D J / Teodorescu, L / Blinov, V E / Bukin, A D / Druzhinin, V P / Golubev, V B / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Todyshev, K Yu / Best, D S / Bondioli, M / Bruinsma, M / Chao, M / Curry, S / Eschrich, I / Kirkby, D / Lankford, A J / Lund, P / Mandelkern, M / Roethel, W / Stoker, D P / Abachi, S / Buchanan, C / Foulkes, S D / Gary, J W / Long, O / Shen, B C / Wang, K / Zhang, L / Hadavand, H K / Hill, E J / Paar, H P / Rahatlou, S / Sharma, V / Berryhill, J W / Campagnari, C / Cunha, A / Dahmes, B / Hong, T M / Kovalskyi, D / Richman, J D / Beck, T W / Eisner, A M / Flacco, C J / Heusch, C A / Kroseberg, J / Lockman, W S / Nesom, G / Schalk, T / Schumm, B A / Seiden, A / Spradlin, P / Williams, D C / Wilson, M G / Albert, J / Chen, E / Cheng, C H / Dvoretskii, A / Fang, F / Hitlin, D G / Narsky, I / Piatenko, T / Porter, F C / Mancinelli, G / Meadows, B T / Mishra, K / Sokoloff, M D / Blanc, F / Bloom, P C / Chen, S / Ford, W T / Hirschauer, J F / Kreisel, A / Nagel, M / Nauenberg, U / Olivas, A / Ruddick, W O / Smith, J G / Ulmer, K A / Wagner, S R / Zhang, J / Chen, A / Eckhart, E A / Soffer, A / Toki, W H / Wilson, R J / Winklmeier, F / Zeng, Q / Altenburg, D D / Feltresi, E / Hauke, A / Jasper, H / Merkel, J / Petzold, A / Spaan, B / Brandt, T / Klose, V / Lacker, H M / Mader, W F / Nogowski, R / Schubert, J / Schubert, K R / Schwierz, R / Sundermann, J E / Volk, A / Bernard, D / Bonneaud, G R / Latour, E / Thiebaux, Ch / Verderi, M / Clark, P J / Gradl, W / Muheim, F / Playfer, S / Robertson, A I / Xie, Y / Andreotti, M / Bettoni, D / Bozzi, C / Calabrese, R / Cibinetto, G / Luppi, E / Negrini, M / Petrella, A / Piemontese, L / Prencipe, E / Anulli, F / Baldini-Ferroli, R / Calcaterra, A / de Sangro, R / Finocchiaro, G / Pacetti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rama, M / Zallo, A / Buzzo, A / Contri, R / Lo Vetere, M / Macri, M M / Monge, M R / Passaggio, S / Patrignani, C / Robutti, E / Santroni, A / Tosi, S / Brandenburg, G / Chaisanguanthum, K S / Lee, C L / Morii, M / Wu, J / Dubitzky, R S / Marks, J / Schenk, S / Uwer, U / Bard, D J / Bhimji, W / Bowerman, D A / Dauncey, P D / Egede, U / Flack, R L / Nash, J A / Nikolich, M B / Panduro Vazquez, W / Behera, P K / Chai, X / Charles, M J / Mallik, U / Meyer, N T / Ziegler, V / Cochran, J / Crawley, H B / Dong, L / Eyges, V / Meyer, W T / Prell, S / Rosenberg, E I / Rubin, A E / Gritsan, A V / Denig, A G / Fritsch, M / Schott, G / Arnaud, N / Davier, M / Grosdidier, G / Höcker, A / Lepeltier, V / Le Diberder, F / Lutz, A M / Oyanguren, A / Pruvot, S / Rodier, S / Roudeau, P / Schune, M H / Serrano, J / Stocchi, A / Wang, W F / Wormser, G / Lange, D J / Wright, D M / Chavez, C A / Forster, I J / Fry, J R / Gabathuler, E / Gamet, R / George, K A / Hutchcroft, D E / Payne, D J / Schofield, K C / Touramanis, C / Bevan, A J / Clarke, C K / Di Lodovico, F / Menges, W / Sacco, R / Cowan, G / Flaecher, H U / Hopkins, D A / Jackson, P S / McMahon, T R / Salvatore, F / Wren, A C / Davis, C L / Allison, J / Barlow, N R / Barlow, R J / Chia, Y M / Edgar, C L / Lafferty, G D / Naisbit, M T / Williams, J C / Yi, J I / Chen, C / Hulsbergen, W D / Jawahery, A / Lae, C K / Roberts, D A / Simi, G / Blaylock, G / Dallapiccola, C / Hertzbach, S S / Li, X / Moore, T B / Saremi, S / Staengle, H / Cowan, R / Sciolla, G / Sekula, S J / Spitznagel, M / Taylor, F / Yamamoto, R K / Kim, H / McLachlin, S E / Patel, P M / Robertson, S H / Lazzaro, A / Lombardo, V / Palombo, F / Bauer, J M / Cremaldi, L / Eschenburg, V / Godang, R / Kroeger, R / Sanders, D A / Summers, D J / Zhao, H W / Brunet, S / Côté, D / Simard, M / Taras, P / Viaud, F B / Nicholson, H / Cavallo, N / De Nardo, G / Fabozzi, F / Gatto, C / Lista, L / Monorchio, D / Paolucci, P / Piccolo, D / Sciacca, C / Baak, M A / Raven, G / Snoek, H L / Jessop, C P / Losecco, J M / Benelli, G / Corwin, L A / Gan, K K / Honscheid, K / Hufnagel, D / Jackson, P D / Kagan, H / Kass, R / Rahimi, A M / Regensburger, J J / Ter-Antonyan, R / Wong, Q K / Blount, N L / Brau, J / Frey, R / Igonkina, O / Kolb, J A / Lu, M / Potter, C T / Rahmat, R / Sinev, N B / Strom, D / Strube, J / Torrence, E / Gaz, A / Margoni, M / Morandin, M / Pompili, A / Posocco, M / Rotondo, M / Simonetto, F / Stroili, R / Voci, C / Benayoun, M / Briand, H / Chauveau, J / David, P / Del Buono, L / de la Vaissière, Ch / Hamon, O / Hartfiel, B L / Leruste, Ph / Malclès, J / Ocariz, J / Roos, L / Therin, G / Gladney, L / Biasini, M / Covarelli, R / Angelini, C / Batignani, G / Bettarini, S / Bucci, F / Calderini, G / Carpinelli, M / Cenci, R / Forti, F / Giorgi, M A / Lusiani, A / Marchiori, G / Mazur, M A / Morganti, M / Neri, N / Paoloni, E / Rizzo, G / Walsh, J J / Haire, M / Judd, D / Wagoner, D E / Biesiada, J / Danielson, N / Elmer, P / Lau, Y P / Lu, C / Olsen, J / Smith, A J S / Telnov, A V / Bellini, F / Cavoto, G / D'Orazio, A / Del Re, D / Di Marco, E / Faccini, R / Ferrarotto, F / Ferroni, F / Gaspero, M / Li Gioi, L / Mazzoni, M A / Morganti, S / Piredda, G / Polci, F / Safai Tehrani, F / Voena, C / Ebert, M / Schröder, H / Waldi, R / Adye, T / Franek, B / Olaiya, E O / Ricciardi, S / Wilson, F F / Aleksan, R / Emery, S / Gaidot, A / Ganzhur, S F / Hamel de Monchenault, G / Kozanecki, W / Legendre, M / Vasseur, G / Yèche, Ch / Zito, M / Chen, X R / Liu, H / Park, W / Purohit, M V / Wilson, J R / Allen, M T / Aston, D / Bartoldus, R / Bechtle, P / Berger, N / Claus, R / Coleman, J P / Convery, M R / Dingfelder, J C / Dorfan, J / Dubois-Felsmann, G P / Dujmic, D / Dunwoodie, W / Field, R C / Glanzman, T / Gowdy, S J / Graham, M T / Grenier, P / Halyo, V / Hast, C / Hryn'ova, T / Innes, W R / Kelsey, M H / Kim, P / Leith, D W G S / Li, S / Luitz, S / Luth, V / Lynch, H L / MacFarlane, D B / Marsiske, H / Messner, R / Muller, D R / O'Grady, C P / Ozcan, V E / Perazzo, A / Perl, M / Pulliam, T / Ratcliff, B N / Roodman, A / Salnikov, A A / Schindler, R H / Schwiening, J / Snyder, A / Stelzer, J / Su, D / Sullivan, M K / Suzuki, K / Swain, S K / Thompson, J M / Va'vra, J / van Bakel, N / Wagner, A P / Weaver, M / Weinstein, A J R / Wisniewski, W J / Wittgen, M / Wright, D H / Wulsin, H W / Yarritu, A K / Yi, K / Young, C C / Burchat, P R / Edwards, A J / Majewski, S A / Petersen, B A / Wilden, L / Ahmed, S / Alam, M S / Bula, R / Ernst, J A / Jain, V / Pan, B / Saeed, M A / Wappler, F R / Zain, S B / Bugg, W / Krishnamurthy, M / Spanier, S M / Eckmann, R / Ritchie, J L / Satpathy, A / Schilling, C J / Schwitters, R F / Izen, J M / Lou, X C / Ye, S / Bianchi, F / Gallo, F / Gamba, D / Bomben, M / Bosisio, L / Cartaro, C / Cossutti, F / Della Ricca, G / Dittongo, S / Lanceri, L / Vitale, L / Azzolini, V / Lopez-March, N / Martinez-Vidal, F / Banerjee, Sw / Bhuyan, B / Brown, C M / Fortin, D / Hamano, K / Kowalewski, R / Nugent, I M / Roney, J M / Sobie, R J / Back, J J / Harrison, P F / Latham, T E / Mohanty, G B / Pappagallo, M / Band, H R / Chen, X / Cheng, B / Dasu, S / Datta, M / Flood, K T / Hollar, J J / Kutter, P E / Mellado, B / Mihalyi, A / Pan, Y / Pierini, M / Prepost, R / Wu, S L / Yu, Z / Neal, H

Physical review letters

2007 Volume 98, Issue 6, Page(s) 61803

Abstract: A search for lepton flavor violating decays of the tau lepton to a lighter mass lepton and a pseudoscalar meson has been performed using 339 fb;{-1} of e;{+}e;{-} annihilation data collected at a center-of-mass energy near 10.58 GeV by the BABAR detector ...

Abstract	A search for lepton flavor violating decays of the tau lepton to a lighter mass lepton and a pseudoscalar meson has been performed using 339 fb;{-1} of e;{+}e;{-} annihilation data collected at a center-of-mass energy near 10.58 GeV by the BABAR detector at the SLAC PEP-II storage ring. No evidence of a signal has been found, and upper limits on the branching fractions are set at the 10;{-7} level.
Language	English
Publishing date	2007-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.98.061803
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 58/153: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Search for the rare decay B-->pil+ l-.

Aubert, B / Bona, M / Boutigny, D / Karyotakis, Y / Lees, J P / Poireau, V / Prudent, X / Tisserand, V / Zghiche, A / Garra Tico, J / Grauges, E / Lopez, L / Palano, A / Eigen, G / Ofte, I / Stugu, B / Sun, L / Abrams, G S / Battaglia, M /

Brown, D N / Button-Shafer, J / Cahn, R N / Groysman, Y / Jacobsen, R G / Kadyk, J A / Kerth, L T / Kolomensky, Yu G / Kukartsev, G / Lopes Pegna, D / Lynch, G / Mir, L M / Orimoto, T J / Pripstein, M / Roe, N A / Ronan, M T / Tackmann, K / Wenzel, W A / del Amo Sanchez, P / Hawkes, C M / Watson, A T / Held, T / Koch, H / Lewandowski, B / Pelizaeus, M / Schroeder, T / Steinke, M / Boyd, J T / Burke, J P / Cottingham, W N / Walker, D / Asgeirsson, D J / Cuhadar-Donszelmann, T / Fulsom, B G / Hearty, C / Knecht, N S / Mattison, T S / McKenna, J A / Khan, A / Saleem, M / Teodorescu, L / Blinov, V E / Bukin, A D / Druzhinin, V P / Golubev, V B / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Todyshev, K Yu / Bondioli, M / Bruinsma, M / Curry, S / Eschrich, I / Kirkby, D / Lankford, A J / Lund, P / Mandelkern, M / Martin, E C / Stoker, D P / Abachi, S / Buchanan, C / Foulkes, S D / Gary, J W / Liu, F / Long, O / Shen, B C / Zhang, L / Paar, H P / Rahatlou, S / Sharma, V / Berryhill, J W / Campagnari, C / Cunha, A / Dahmes, B / Hong, T M / Kovalskyi, D / Richman, J D / Beck, T W / Eisner, A M / Flacco, C J / Heusch, C A / Kroseberg, J / Lockman, W S / Schalk, T / Schumm, B A / Seiden, A / Williams, D C / Wilson, M G / Winstrom, L O / Chen, E / Cheng, C H / Dvoretskii, A / Fang, F / Hitlin, D G / Narsky, I / Piatenko, T / Porter, F C / Mancinelli, G / Meadows, B T / Mishra, K / Sokoloff, M D / Blanc, F / Bloom, P C / Chen, S / Ford, W T / Hirschauer, J F / Kreisel, A / Nagel, M / Nauenberg, U / Olivas, A / Smith, J G / Ulmer, K A / Wagner, S R / Zhang, J / Chen, A / Eckhart, E A / Soffer, A / Toki, W H / Wilson, R J / Winklmeier, F / Zeng, Q / Altenburg, D D / Feltresi, E / Hauke, A / Jasper, H / Merkel, J / Petzold, A / Spaan, B / Wacker, K / Brandt, T / Klose, V / Lacker, H M / Mader, W F / Nogowski, R / Schubert, J / Schubert, K R / Schwierz, R / Sundermann, J E / Volk, A / Bernard, D / Bonneaud, G R / Latour, E / Thiebaux, Ch / Verderi, M / Clark, P J / Gradl, W / Muheim, F / Playfer, S / Robertson, A I / Xie, Y / Andreotti, M / Bettoni, D / Bozzi, C / Calabrese, R / Cecchi, A / Cibinetto, G / Franchini, P / Luppi, E / Negrini, M / Petrella, A / Piemontese, L / Prencipe, E / Santoro, V / Anulli, F / Baldini-Ferroli, R / Calcaterra, A / de Sangro, R / Finocchiaro, G / Pacetti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rama, M / Zallo, A / Buzzo, A / Contri, R / Lo Vetere, M / Macri, M M / Monge, M R / Passaggio, S / Patrignani, C / Robutti, E / Santroni, A / Tosi, S / Chaisanguanthum, K S / Morii, M / Wu, J / Dubitzky, R S / Marks, J / Schenk, S / Uwer, U / Bard, D J / Dauncey, P D / Flack, R L / Nash, J A / Nikolich, M B / Panduro Vazquez, W / Behera, P K / Chai, X / Charles, M J / Mallik, U / Meyer, N T / Ziegler, V / Cochran, J / Crawley, H B / Dong, L / Eyges, V / Meyer, W T / Prell, S / Rosenberg, E I / Rubin, A E / Gritsan, A V / Lae, C K / Denig, A G / Fritsch, M / Schott, G / Arnaud, N / Béquilleux, J / Davier, M / Grosdidier, G / Höcker, A / Lepeltier, V / Le Diberder, F / Lutz, A M / Pruvot, S / Rodier, S / Roudeau, P / Schune, M H / Serrano, J / Sordini, V / Stocchi, A / Wang, W F / Wormser, G / Lange, D J / Wright, D M / Chavez, C A / Forster, I J / Fry, J R / Gabathuler, E / Gamet, R / Hutchcroft, D E / Payne, D J / Schofield, K C / Touramanis, C / Bevan, A J / George, K A / Di Lodovico, F / Menges, W / Sacco, R / Cowan, G / Flaecher, H U / Hopkins, D A / Jackson, P S / McMahon, T R / Salvatore, F / Wren, A C / Davis, C L / Allison, J / Barlow, N R / Barlow, R J / Chia, Y M / Edgar, C L / Lafferty, G D / West, T J / Yi, J I / Anderson, J / Chen, C / Jawahery, A / Roberts, D A / Simi, G / Tuggle, J M / Blaylock, G / Dallapiccola, C / Hertzbach, S S / Li, X / Moore, T B / Salvati, E / Saremi, S / Cowan, R / Fisher, P H / Sciolla, G / Sekula, S J / Spitznagel, M / Taylor, F / Yamamoto, R K / Kim, H / McLachlin, S E / Patel, P M / Robertson, S H / Lazzaro, A / Lombardo, V / Palombo, F / Bauer, J M / Cremaldi, L / Eschenburg, V / Godang, R / Kroeger, R / Sanders, D A / Summers, D J / Zhao, H W / Brunet, S / Côté, D / Simard, M / Taras, P / Viaud, F B / Nicholson, H / De Nardo, G / Fabozzi, F / Lista, L / Monorchio, D / Sciacca, C / Baak, M A / Raven, G / Snoek, H L / Jessop, C P / LoSecco, J M / Benelli, G / Corwin, L A / Gan, K K / Honscheid, K / Hufnagel, D / Kagan, H / Kass, R / Morris, J P / Rahimi, A M / Regensburger, J J / Ter-Antonyan, R / Wong, Q K / Blount, N L / Brau, J / Frey, R / Igonkina, O / Kolb, J A / Lu, M / Rahmat, R / Sinev, N B / Strom, D / Strube, J / Torrence, E / Gagliardi, N / Gaz, A / Margoni, M / Morandin, M / Pompili, A / Posocco, M / Rotondo, M / Simonetto, F / Stroili, R / Voci, C / Ben-Haim, E / Briand, H / Chauveau, J / David, P / Del Buono, L / de la Vaissière, Ch / Hamon, O / Hartfiel, B L / Leruste, Ph / Malclès, J / Ocariz, J / Perez, A / Gladney, L / Biasini, M / Covarelli, R / Manoni, E / Angelini, C / Batignani, G / Bettarini, S / Calderini, G / Carpinelli, M / Cenci, R / Forti, F / Giorgi, M A / Lusiani, A / Marchiori, G / Mazur, M A / Morganti, M / Neri, N / Paoloni, E / Rizzo, G / Walsh, J J / Haire, M / Biesiada, J / Elmer, P / Lau, Y P / Lu, C / Olsen, J / Smith, A J S / Telnov, A V / Baracchini, E / Bellini, F / Cavoto, G / D'Orazio, A / del Re, D / Di Marco, E / Faccini, R / Ferrarotto, F / Ferroni, F / Gaspero, M / Jackson, P D / Li Gioi, L / Mazzoni, M A / Morganti, S / Piredda, G / Polci, F / Renga, F / Voena, C / Ebert, M / Schröder, H / Waldi, R / Adye, T / Castelli, G / Franek, B / Olaiya, E O / Ricciardi, S / Roethel, W / Wilson, F F / Aleksan, R / Emery, S / Escalier, M / Gaidot, A / Ganzhur, S F / Hamel de Monchenault, G / Kozanecki, W / Legendre, M / Vasseur, G / Yèche, Ch / Zito, M / Chen, X R / Liu, H / Park, W / Purohit, M V / Wilson, J R / Allen, M T / Aston, D / Bartoldus, R / Bechtle, P / Berger, N / Claus, R / Coleman, J P / Convery, M R / Dingfelder, J C / Dorfan, J / Dubois-Felsmann, G P / Dujmic, D / Dunwoodie, W / Field, R C / Glanzman, T / Gowdy, S J / Graham, M T / Grenier, P / Halyo, V / Hast, C / Hryn'ova, T / Innes, W R / Kelsey, M H / Kim, P / Leith, D W G S / Li, S / Luitz, S / Luth, V / Lynch, H L / MacFarlane, D B / Marsiske, H / Messner, R / Muller, D R / O'Grady, C P / Ozcan, V E / Perazzo, A / Perl, M / Pulliam, T / Ratcliff, B N / Roodman, A / Salnikov, A A / Schindler, R H / Schwiening, J / Snyder, A / Stelzer, J / Su, D / Sullivan, M K / Suzuki, K / Swain, S K / Thompson, J M / Va'vra, J / van Bakel, N / Wagner, A P / Weaver, M / Wisniewski, W J / Wittgen, M / Wright, D H / Yarritu, A K / Yi, K / Young, C C / Burchat, P R / Edwards, A J / Majewski, S A / Petersen, B A / Wilden, L / Ahmed, S / Alam, M S / Bula, R / Ernst, J A / Jain, V / Pan, B / Saeed, M A / Wappler, F R / Zain, S B / Bugg, W / Krishnamurthy, M / Spanier, S M / Eckmann, R / Ritchie, J L / Ruland, A M / Schilling, C J / Schwitters, R F / Izen, J M / Lou, X C / Ye, S / Bianchi, F / Gallo, F / Gamba, D / Pelliccioni, M / Bomben, M / Bosisio, L / Cartaro, C / Cossutti, F / Della Ricca, G / Lanceri, L / Vitale, L / Azzolini, V / Lopez-March, N / Martinez-Vidal, F / Milanes, D A / Oyanguren, A / Albert, J / Banerjee, Sw / Bhuyan, B / Hamano, K / Kowalewski, R / Nugent, I M / Roney, J M / Sobie, R J / Back, J J / Harrison, P F / Latham, T E / Mohanty, G B / Pappagallo, M / Band, H R / Chen, X / Dasu, S / Flood, K T / Hollar, J J / Kutter, P E / Pan, Y / Pierini, M / Prepost, R / Wu, S L / Yu, Z / Neal, H

Physical review letters

2007 Volume 99, Issue 5, Page(s) 51801

Abstract: We have performed a search for the flavor-changing neutral-current decays B-->pil+ l-, where l+ l ... branching fraction to be B(B-->pil+ l-)<9.1 x 10(-8) at 90% confidence level. We also search for the lepton ...

Abstract	We have performed a search for the flavor-changing neutral-current decays B-->pil+ l-, where l+ l- is either e+ e- or mu+ mu-, using a sample of 230 x 10(6) Upsilon(4S)-->BB decays collected with the BABAR detector. We observe no evidence of a signal and measure the upper limit on the isospin-averaged branching fraction to be B(B-->pil+ l-)<9.1 x 10(-8) at 90% confidence level. We also search for the lepton-flavor-violating decays B-->pie+/- mu-/+ and measure an upper limit on the isospin-averaged branching fraction of B(B-->pie+/- mu-/+)<9.2 x 10(-8) at 90% confidence level.
Language	English
Publishing date	2007-08-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.99.051801
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 58/153: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine.

Long, Alexandra J / Clifton, Ian J / Roach, Peter L / Baldwin, Jack E / Rutledge, Peter J / Schofield, Christopher J

Biochemistry

2005 Volume 44, Issue 17, Page(s) 6619–6628

Abstract: ... of the tripeptide delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-valine (ACV) to bicyclic isopenicillin N (IPN ... analogues delta-(l-alpha-aminoadipoyl)-l-cysteinyl-glycine (ACG) and delta-(l-alpha-aminoadipoyl)-l ...

Abstract	Isopenicillin N synthase (IPNS), a non-heme iron(II)-dependent oxidase, catalyzes conversion of the tripeptide delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-valine (ACV) to bicyclic isopenicillin N (IPN), concomitant with the reduction of dioxygen to two molecules of water. Incubation of the "truncated"substrate analogues delta-(l-alpha-aminoadipoyl)-l-cysteinyl-glycine (ACG) and delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alanine (ACA) with IPNS has previously been shown to afford acyclic products, in which the substrate cysteinyl residue has undergone a two-electron oxidation. We report X-ray crystal structures for the anaerobic IPNS/Fe(II)/ACG and IPNS/Fe(II)/ACA complexes, both in the absence and presence of the dioxygen analogue nitric oxide. The overall protein structures are very similar to those of the corresponding IPNS/Fe(II)/ACV complexes; however, significant differences are apparent in the vicinity of the active site iron. The structure of the IPNS/Fe(II)/ACG complex reveals that the C-terminal carboxylate of this substrate is oriented toward the active site iron atom, apparently hydrogen-bonded to an additional water ligand at the metal; this is a different binding mode to that observed in the IPNS/Fe(II)/ACV complex. ACA binds to the metal in a manner that is intermediate between those observed for ACV and ACG. The addition of NO to these complexes initiates conformational changes such that both the IPNS/Fe(II)/ACG/NO and IPNS/Fe(II)/ACA/NO structures closely resemble the IPNS/Fe(II)/ACV/NO complex. These results further demonstrate the feasibility of metal-centered rearrangements in catalysis by non-heme iron enzymes and provide insight into the delicate balance between hydrophilic-hydrophobic interactions and steric effects in the IPNS active site.
MeSH term(s)	Alanine/chemistry ; Anaerobiosis ; Binding Sites ; Catalysis ; Crystallization ; Crystallography, X-Ray ; Emericella/enzymology ; Ferrous Compounds/chemistry ; Ferrous Compounds/metabolism ; Glycine/chemistry ; Nitric Oxide/chemistry ; Nitric Oxide/metabolism ; Oligopeptides/chemical synthesis ; Oligopeptides/metabolism ; Oxidoreductases/chemistry ; Oxidoreductases/metabolism ; Penicillins/chemistry ; Penicillins/metabolism ; Substrate Specificity
Chemical Substances	Ferrous Compounds ; Oligopeptides ; Penicillins ; aminoadipoyl-cysteinyl-allylglycine ; Nitric Oxide (31C4KY9ESH) ; Oxidoreductases (EC 1.-) ; isopenicillin N synthetase (EC 1.21.3.1) ; Alanine (OF5P57N2ZX) ; Glycine (TE7660XO1C)
Language	English
Publishing date	2005-05-03
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1108-3
ISSN	1520-4995 ; 0006-2960
ISSN (online)	1520-4995
ISSN	0006-2960
DOI	10.1021/bi047478q
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 217: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.

Ducho, Christian / Hamed, Refaat B / Batchelar, Edward T / Sorensen, John L / Odell, Barbara / Schofield, Christopher J

Organic & biomolecular chemistry

2009 Volume 7, Issue 13, Page(s) 2770–2779

Abstract: L-glutamate semialdehyde (L-GSA) is an intermediate in biosynthetic pathways including ... L-GSA suitable for use in mechanistic studies. Regioselective deuterium incorporation into the 5 ... position of L-GSA was achieved using a labelled form of the Schwartz reagent (Cp2Zr2HCl). 4,4-Dideuterated ...

Abstract	L-glutamate semialdehyde (L-GSA) is an intermediate in biosynthetic pathways including those leading to the carbapenem antibiotics. We describe studies on asymmetric deuteration or hydrogenation of appropriate didehydro-amino acid precursors for the stereoselective synthesis of C-2- and/or C-3-[2H]-labelled L-GSA suitable for use in mechanistic studies. Regioselective deuterium incorporation into the 5-position of L-GSA was achieved using a labelled form of the Schwartz reagent (Cp2Zr2HCl). 4,4-Dideuterated and fully backbone deuterated L-GSAs were prepared. The application of the labelled L-GSA derivatives to biosynthetic studies was exemplified by the chemo-enzymatic preparation of selectively deuterated trans-carboxymethylprolines using two different carboxymethylproline synthases (CarB and ThnE), enzymes that catalyse early steps in the biosynthesis of two carbapenems: (5R)-carbapenem-3-carboxylate and thienamycin, respectively.
MeSH term(s)	Carbapenems/biosynthesis ; Carbapenems/chemistry ; Deuterium/chemistry ; Glutamates/chemical synthesis ; Glutamates/chemistry ; Glutamates/metabolism ; Hydrogenation ; Isotope Labeling ; Molecular Conformation ; Stereoisomerism
Chemical Substances	Carbapenems ; Glutamates ; glutamic acid gamma-semialdehyde (496-92-4) ; Deuterium (AR09D82C7G)
Language	English
Publishing date	2009-05-11
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2097583-1
ISSN	1477-0539 ; 1477-0520
ISSN (online)	1477-0539
ISSN	1477-0520
DOI	10.1039/b903312b
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Search for lepton flavor violating decays tau+/--->l+/-omega.

Aubert, B / Bona, M / Karyotakis, Y / Lees, J P / Poireau, V / Prudent, X / Tisserand, V / Zghiche, A / Garra Tico, J / Grauges, E / Lopez, L / Palano, A / Pappagallo, M / Eigen, G / Stugu, B / Sun, L / Abrams, G S / Battaglia, M / Brown, D N /

Button-Shafer, J / Cahn, R N / Jacobsen, R G / Kadyk, J A / Kerth, L T / Kolomensky, Yu G / Kukartsev, G / Lopes Pegna, D / Lynch, G / Orimoto, T J / Osipenkov, I L / Ronan, M T / Tackmann, K / Tanabe, T / Wenzel, W A / Del Amo Sanchez, P / Hawkes, C M / Soni, N / Watson, A T / Koch, H / Schroeder, T / Walker, D / Asgeirsson, D J / Cuhadar-Donszelmann, T / Fulsom, B G / Hearty, C / Mattison, T S / McKenna, J A / Barrett, M / Khan, A / Saleem, M / Teodorescu, L / Blinov, V E / Bukin, A D / Buzykaev, A R / Druzhinin, V P / Golubev, V B / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Todyshev, K Yu / Bondioli, M / Curry, S / Eschrich, I / Kirkby, D / Lankford, A J / Lund, P / Mandelkern, M / Martin, E C / Stoker, D P / Abachi, S / Buchanan, C / Gary, J W / Liu, F / Long, O / Shen, B C / Vitug, G M / Zhang, L / Paar, H P / Rahatlou, S / Sharma, V / Berryhill, J W / Campagnari, C / Cunha, A / Dahmes, B / Hong, T M / Kovalskyi, D / Richman, J D / Beck, T W / Eisner, A M / Flacco, C J / Heusch, C A / Kroseberg, J / Lockman, W S / Schalk, T / Schumm, B A / Seiden, A / Wilson, M G / Winstrom, L O / Chen, E / Cheng, C H / Echenard, B / Fang, F / Hitlin, D G / Narsky, I / Piatenko, T / Porter, F C / Andreassen, R / Mancinelli, G / Meadows, B T / Mishra, K / Sokoloff, M D / Blanc, F / Bloom, P C / Ford, W T / Hirschauer, J F / Kreisel, A / Nagel, M / Nauenberg, U / Olivas, A / Smith, J G / Ulmer, K A / Wagner, S R / Zhang, J / Ayad, R / Gabareen, A M / Soffer, A / Toki, W H / Wilson, R J / Altenburg, D D / Feltresi, E / Hauke, A / Jasper, H / Merkel, J / Petzold, A / Spaan, B / Wacker, K / Klose, V / Kobel, M J / Lacker, H M / Mader, W F / Nogowski, R / Schubert, J / Schubert, K R / Schwierz, R / Sundermann, J E / Volk, A / Bernard, D / Bonneaud, G R / Latour, E / Lombardo, V / Thiebaux, Ch / Verderi, M / Clark, P J / Gradl, W / Muheim, F / Playfer, S / Robertson, A I / Watson, J E / Xie, Y / Andreotti, M / Bettoni, D / Bozzi, C / Calabrese, R / Cecchi, A / Cibinetto, G / Franchini, P / Luppi, E / Negrini, M / Petrella, A / Piemontese, L / Prencipe, E / Santoro, V / Anulli, F / Baldini-Ferroli, R / Calcaterra, A / de Sangro, R / Finocchiaro, G / Pacetti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rama, M / Zallo, A / Buzzo, A / Contri, R / Lo Vetere, M / Macri, M M / Monge, M R / Passaggio, S / Patrignani, C / Robutti, E / Santroni, A / Tosi, S / Chaisanguanthum, K S / Morii, M / Wu, J / Dubitzky, R S / Marks, J / Schenk, S / Uwer, U / Bard, D J / Dauncey, P D / Nash, J A / Panduro Vazquez, W / Tibbetts, M / Behera, P K / Chai, X / Charles, M J / Mallik, U / Cochran, J / Crawley, H B / Dong, L / Eyges, V / Meyer, W T / Prell, S / Rosenberg, E I / Rubin, A E / Gao, Y Y / Gritsan, A V / Guo, Z J / Lae, C K / Denig, A G / Fritsch, M / Schott, G / Arnaud, N / Béquilleux, J / D'Orazio, A / Davier, M / Grosdidier, G / Höcker, A / Lepeltier, V / Le Diberder, F / Lutz, A M / Pruvot, S / Roudeau, P / Schune, M H / Serrano, J / Sordini, V / Stocchi, A / Wang, W F / Wormser, G / Lange, D J / Wright, D M / Bingham, I / Burke, J P / Chavez, C A / Fry, J R / Gabathuler, E / Gamet, R / Hutchcroft, D E / Payne, D J / Schofield, K C / Touramanis, C / Bevan, A J / George, K A / Di Lodovico, F / Sacco, R / Cowan, G / Flaecher, H U / Hopkins, D A / Paramesvaran, S / Salvatore, F / Wren, A C / Davis, C L / Barlow, N R / Barlow, R J / Chia, Y M / Edgar, C L / Lafferty, G D / West, T J / Yi, J I / Anderson, J / Chen, C / Jawahery, A / Roberts, D A / Simi, G / Tuggle, J M / Dallapiccola, C / Hertzbach, S S / Li, X / Moore, T B / Salvati, E / Saremi, S / Cowan, R / Dujmic, D / Fisher, P H / Koeneke, K / Sciolla, G / Spitznagel, M / Taylor, F / Yamamoto, R K / Zhao, M / McLachlin, S E / Patel, P M / Robertson, S H / Lazzaro, A / Palombo, F / Bauer, J M / Cremaldi, L / Eschenburg, V / Godang, R / Kroeger, R / Sanders, D A / Summers, D J / Zhao, H W / Brunet, S / Côté, D / Simard, M / Taras, P / Viaud, F B / Nicholson, H / De Nardo, G / Fabozzi, F / Lista, L / Monorchio, D / Sciacca, C / Baak, M A / Raven, G / Snoek, H L / Jessop, C P / Knoepfel, K J / Losecco, J M / Benelli, G / Corwin, L A / Honscheid, K / Kagan, H / Kass, R / Morris, J P / Rahimi, A M / Regensburger, J J / Sekula, S J / Wong, Q K / Blount, N L / Brau, J / Frey, R / Igonkina, O / Kolb, J A / Lu, M / Rahmat, R / Sinev, N B / Strom, D / Strube, J / Torrence, E / Gagliardi, N / Gaz, A / Margoni, M / Morandin, M / Pompili, A / Posocco, M / Rotondo, M / Simonetto, F / Stroili, R / Voci, C / Ben-Haim, E / Briand, H / Calderini, G / Chauveau, J / David, P / Del Buono, L / de la Vaissière, Ch / Hamon, O / Leruste, Ph / Malclès, J / Ocariz, J / Perez, A / Prendki, J / Gladney, L / Biasini, M / Covarelli, R / Manoni, E / Angelini, C / Batignani, G / Bettarini, S / Carpinelli, M / Cenci, R / Cervelli, A / Forti, F / Giorgi, M A / Lusiani, A / Marchiori, G / Mazur, M A / Morganti, M / Neri, N / Paoloni, E / Rizzo, G / Walsh, J J / Biesiada, J / Lau, Y P / Lu, C / Olsen, J / Smith, A J S / Telnov, A V / Baracchini, E / Bellini, F / Cavoto, G / Del Re, D / Di Marco, E / Faccini, R / Ferrarotto, F / Ferroni, F / Gaspero, M / Jackson, P D / Mazzoni, M A / Morganti, S / Piredda, G / Polci, F / Renga, F / Voena, C / Ebert, M / Hartmann, T / Schröder, H / Waldi, R / Adye, T / Castelli, G / Franek, B / Olaiya, E O / Roethel, W / Wilson, F F / Emery, S / Escalier, M / Gaidot, A / Ganzhur, S F / Hamel de Monchenault, G / Kozanecki, W / Vasseur, G / Yèche, Ch / Zito, M / Chen, X R / Liu, H / Park, W / Purohit, M V / White, R M / Wilson, J R / Allen, M T / Aston, D / Bartoldus, R / Bechtle, P / Claus, R / Coleman, J P / Convery, M R / Dingfelder, J C / Dorfan, J / Dubois-Felsmann, G P / Dunwoodie, W / Field, R C / Glanzman, T / Gowdy, S J / Graham, M T / Grenier, P / Hast, C / Innes, W R / Kaminski, J / Kelsey, M H / Kim, H / Kim, P / Kocian, M L / Leith, D W G S / Li, S / Luitz, S / Luth, V / Lynch, H L / Macfarlane, D B / Marsiske, H / Messner, R / Muller, D R / Nelson, S / O'Grady, C P / Ofte, I / Perazzo, A / Perl, M / Pulliam, T / Ratcliff, B N / Roodman, A / Salnikov, A A / Schindler, R H / Schwiening, J / Snyder, A / Su, D / Sullivan, M K / Suzuki, K / Swain, S K / Thompson, J M / Va'vra, J / Wagner, A P / Weaver, M / Wisniewski, W J / Wittgen, M / Wright, D H / Wulsin, H W / Yarritu, A K / Yi, K / Young, C C / Ziegler, V / Burchat, P R / Edwards, A J / Majewski, S A / Miyashita, T S / Petersen, B A / Wilden, L / Ahmed, S / Alam, M S / Bula, R / Ernst, J A / Pan, B / Saeed, M A / Zain, S B / Spanier, S M / Wogsland, B J / Eckmann, R / Ritchie, J L / Ruland, A M / Schilling, C J / Schwitters, R F / Izen, J M / Lou, X C / Ye, S / Bianchi, F / Gallo, F / Gamba, D / Pelliccioni, M / Bomben, M / Bosisio, L / Cartaro, C / Cossutti, F / Della Ricca, G / Lanceri, L / Vitale, L / Azzolini, V / Lopez-March, N / Martinez-Vidal, F / Milanes, D A / Oyanguren, A / Albert, J / Banerjee, Sw / Bhuyan, B / Hamano, K / Kowalewski, R / Nugent, I M / Roney, J M / Sobie, R J / Harrison, P F / Ilic, J / Latham, T E / Mohanty, G B / Band, H R / Chen, X / Dasu, S / Flood, K T / Hollar, J J / Kutter, P E / Pan, Y / Pierini, M / Prepost, R / Wu, S L / Neal, H

Physical review letters

2008 Volume 100, Issue 7, Page(s) 71802

Abstract: A search for lepton flavor violating decays of a tau to a lighter-mass charged lepton and an omega vector meson is performed using 384.1 fb(-1) of e(+)e(-) annihilation data collected with the BABAR detector at the Stanford Linear Accelerator Center PEP- ... ...

Abstract	A search for lepton flavor violating decays of a tau to a lighter-mass charged lepton and an omega vector meson is performed using 384.1 fb(-1) of e(+)e(-) annihilation data collected with the BABAR detector at the Stanford Linear Accelerator Center PEP-II storage ring. No signal is found, and the upper limits on the branching ratios are determined to be B(tau(+/-)-->e;{+/-}omega)<1.1 x10 (-7) and B(tau(+/-)-->micro(+/-)omega)<1.0 x 10(-7) at 90% confidence level.
Language	English
Publishing date	2008-02-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.100.071802
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 58/153: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Attractancy toOryzaephilus surinamensis (L.) of volatile materials isolated from vacuum distillate of heat-treated carobs.

Stubbs, M R / Chambers, J / Schofield, S B / Wilkins, J P

Journal of chemical ecology

2013 Volume 11, Issue 5, Page(s) 565–581

Abstract: ... to adultOryzaephilus surinamensis (L.). The materials responsible for the aroma were isolated from the distillate by saturating ...

Abstract	Vacuum distillation of heat-treated carobs gave an aqueous, colorless, sweet-smelling distillate which was tested over a wide range of concentrations and found to be highly attractive to adultOryzaephilus surinamensis (L.). The materials responsible for the aroma were isolated from the distillate by saturating with sodium chloride and extracting into diethyl ether as separate acidic, neutral, and basic fractions. The extraction efficiency was checked by recombining portions of the three fractions and replacing the diethyl ether with water to give a "reconstituted distillate;" this was almost as attractive as the original distillate. Bioassay of aqueous solutions of the three separate fractions showed that the acidic was attractive, while the neutral and basic had little effect. The five major components of the acidic fraction were found to be acetic, isobutyric,n-butyric, 2-methylbutyric, and hexanoic (caproic) acids. Bioassay of these in aqueous solution, both separately and combined, showed that hexanoic acid was the most attractive and may be responsible for both the longer-lasting attractive effect of the carob distillate and for the effectiveness of carobs themselves used in bait bags to detect stored product insects.
Language	English
Publishing date	2013-12-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	800130-3
ISSN	1573-1561 ; 0098-0331
ISSN (online)	1573-1561
ISSN	0098-0331
DOI	10.1007/BF00988568
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 76/724: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED