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Article ; Online: Emergent ultrasmall multiferroics in paraelectric perovskite oxide by hole polarons.

Xu, Tao / Mori, Masataka / Hirakata, Hiroyuki / Kitamura, Takayuki / Shimada, Takahiro

Physical chemistry chemical physics : PCCP

2024 Volume 26, Issue 2, Page(s) 842–847

Abstract: Ultimately small multiferroics with coupled ferroelectric and ferromagnetic order parameters have drawn considerable attention for their tremendous technological potential. Nevertheless, these ferroic orders inevitably disappear below the critical size ... ...

Abstract	Ultimately small multiferroics with coupled ferroelectric and ferromagnetic order parameters have drawn considerable attention for their tremendous technological potential. Nevertheless, these ferroic orders inevitably disappear below the critical size of several nanometers in conventional ferroelectrics or multiferroics. Here, based on first-principles calculations, we propose a new strategy to overcome this limitation and create ultrasmall multiferroic elements in otherwise nonferroelectric CaTiO
Language	English
Publishing date	2024-01-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d3cp05364d
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Article: Case report: Pathological complete response of pregnancy associated pulmonary enteric adenocarcinoma to chemoradiotherapy.

Nemoto, Yukiko / Kuroda, Koji / Oyama, Rintaro / Mori, Masataka / Shimajiri, Shohei / Tanaka, Fumihiro

Frontiers in oncology

2024 Volume 14, Page(s) 1290757

Abstract: Pulmonary enteric adenocarcinoma (PEAC) is a rare lung adenocarcinoma with morphological features similar to those of primary and metastatic colorectal adenocarcinoma. To date, only a few studies have reported the therapeutic effects of chemoradiotherapy ...

Abstract	Pulmonary enteric adenocarcinoma (PEAC) is a rare lung adenocarcinoma with morphological features similar to those of primary and metastatic colorectal adenocarcinoma. To date, only a few studies have reported the therapeutic effects of chemoradiotherapy on PEAC. This report describes the case of a 28-year-old woman with pregnancy-related PEAC who presented with left shoulder pain. A superior sulcus tumor was identified in the left thoracic cavity, and the biopsy indicated more than 50% intestinal differentiation components. Moreover, immunohistochemical staining revealed positive CDX2 and CK7 expression. Positron emission tomography-computed tomography, upper endoscopy, colonoscopy, and small intestinal capsule endoscopy revealed no gastrointestinal malignancies. The patient was diagnosed with locally advanced PEAC (clinical stage T4N0M0; stage IIIA). Therefore, the patient was treated with preoperative chemoradiotherapy and underwent gross total resection during surgery. Pathological evaluation of the specimen revealed no residual tumor, indicating that the chemoradiotherapy for PEAC was highly effective. One subsequent brain metastasis was also resected, and the patient has not experienced recurrence in 28 months since this resection and continues to be monitored regularly. This is the first pathologically confirmed report of the use of chemoradiotherapy (carboplatin [CBDCA] and paclitaxel [PTX]) for PEAC and its clinical efficacy. Unlike previous reports, the efficacy of this treatment is attributed to the use of PTX in preoperative chemotherapy and the p21- status of the patient, which may have increased sensitivity to chemoradiation therapy. Therefore, chemoradiotherapy (CBDCA + PTX) may be a viable treatment option for advanced intestinal lung adenocarcinoma.
Language	English
Publishing date	2024-02-23
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2024.1290757
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Article ; Online: Genetic mutation in

Tsukimi, Tomoya / Obana, Nozomu / Shigemori, Suguru / Arakawa, Kazuharu / Miyauchi, Eiji / Yang, Jiayue / Song, Isaiah / Ashino, Yujin / Wakayama, Masataka / Soga, Tomoyoshi / Tomita, Masaru / Ohno, Hiroshi / Mori, Hirotada / Fukuda, Shinji

mSystems

2024 Volume 9, Issue 2, Page(s) e0112323

Abstract: Mammalian gut microbes colonize the intestinal tract of their host and adapt to establish a microbial ecosystem. The host diet changes the nutrient profile of the intestine and has a high impact on microbiota composition. Genetic mutations ... ...

Abstract	Mammalian gut microbes colonize the intestinal tract of their host and adapt to establish a microbial ecosystem. The host diet changes the nutrient profile of the intestine and has a high impact on microbiota composition. Genetic mutations in
MeSH term(s)	Humans ; Animals ; Mice ; Escherichia coli/genetics ; Ecosystem ; Diet ; Intestines/microbiology ; Mutation ; Mammals
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ISSN	2379-5077
ISSN (online)	2379-5077
DOI	10.1128/msystems.01123-23
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Article: [The Outcome of Multiple Lung Cancer Cases with Two-stage Surgery].

Takenaka, Masaru / Mori, Masataka / Tanaka, Fumihiro

Kyobu geka. The Japanese journal of thoracic surgery

2021 Volume 74, Issue 1, Page(s) 54–61

Abstract: Backgrounds: There is an increasing number of cases of two-stage surgery for synchronous or metachronous lung cancer. We discuss the surgical treatment strategy for multiple lung cancers.: Methods: We retrospectively reviewed the clinicopathological ... ...

Abstract	Backgrounds: There is an increasing number of cases of two-stage surgery for synchronous or metachronous lung cancer. We discuss the surgical treatment strategy for multiple lung cancers. Methods: We retrospectively reviewed the clinicopathological factors and prognosis of 105 patients (210 surgeries) who underwent two-stage surgery for lung cancer during the period from 2010 to 2019 in our department. Results: A total of 105 cases were reviewed;58 males and 47 females, 67 were synchronous and 38 were metachronous. Long-term prognosis of death from other diseases due to respiratory diseases was found in eight patients (7.6%). Recurrence of lung cancer was observed in 29 (27.6%), and cancer death was found in 9 of them. The overall three-year and five-year survival rates were 85.3% and 71.3 %, respectively. The absence of ground-glass opacity components in the tumor( p=0.036) and advanced pathological stage( p=0.048) were significantly associated with postoperative recurrence. Conclusions: The recurrence rate was high in cases of solid tumors and advanced pathological stage, even in multiple lung cancers. Thus, an appropriate combination of limited surgery and standard surgery should be used, taking into account the nature of the tumor and the patient's ability to tolerate the surgery.
MeSH term(s)	Female ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Prognosis ; Retrospective Studies
Language	Japanese
Publishing date	2021-01-10
Publishing country	Japan
Document type	Journal Article
ZDB-ID	603899-2
ISSN	0021-5252
ISSN	0021-5252
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Article ; Online: Chest wall stabilization with intercostal

Mori, Masataka / Yoshimatsu, Katsuma / Shinohara, Shinji / Tanaka, Fumihiro

Trauma case reports

2020 Volume 28, Page(s) 100311

Abstract: Choosing an optimal procedure to stabilize the chest wall for multiple rib fractures can be challenging for surgeons. Stabilization with rib plates or intramedullary devices requires exposure of fractured bones, whereas chest stabilization with ... ...

Abstract	Choosing an optimal procedure to stabilize the chest wall for multiple rib fractures can be challenging for surgeons. Stabilization with rib plates or intramedullary devices requires exposure of fractured bones, whereas chest stabilization with intercostal
Language	English
Publishing date	2020-05-22
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2835433-3
ISSN	2352-6440 ; 2352-6440
ISSN (online)	2352-6440
ISSN	2352-6440
DOI	10.1016/j.tcr.2020.100311
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Article: [Carinal Resection with Lung Resection and Perioperative Management].

Mori, Masataka / Takenaka, Masaru / Tanaka, Fumihiro

Kyobu geka. The Japanese journal of thoracic surgery

2020 Volume 73, Issue 10, Page(s) 834–839

Abstract: Carinal resection with lung resection is a rare surgical procedure with high risk. In-hospital mortality rates for carinal reconstruction and sleeve pneumonectomy were 6.5% and 16.7%, respectively. Thus, thoracic surgeons need to learn the procedure for ... ...

Abstract	Carinal resection with lung resection is a rare surgical procedure with high risk. In-hospital mortality rates for carinal reconstruction and sleeve pneumonectomy were 6.5% and 16.7%, respectively. Thus, thoracic surgeons need to learn the procedure for patients who need the surgery. This time, we will account for preoperative evaluation, intraoperative advice, and postoperative management in carinal resection with right upper lobectomy presenting 2 cases in our hospital. Case 1 had a high caliber mismatch of bronchial stumps because of partial carinal resection, which was corrected by simple sutures of the anterior cartilage. That allowed us to perform sleeve right upper lobectomy avoiding carinal reconstruction. Case 2 was a case in which lung and bronchial tissue sticking to mediastinum due to obstructive pneumonia prevented us from anastomosing intermediate bronchus to the trachea or left main bronchus. We had to choose sleeve right pneumonectomy, and a fistula on the anastomotic site occurred later resulting in a bad course. We hope our experiences aid future patients who need the carinal resection.
MeSH term(s)	Bronchi ; Humans ; Lung Neoplasms/surgery ; Pneumonectomy ; Thoracic Surgical Procedures ; Trachea
Language	Japanese
Publishing date	2020-10-22
Publishing country	Japan
Document type	Journal Article
ZDB-ID	603899-2
ISSN	0021-5252
ISSN	0021-5252
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Article ; Online: A case of tocilizumab-refractory idiopathic multicentric Castleman's disease successfully treated with sirolimus.

Sumiyoshi, Remi / Koga, Tomohiro / Furukawa, Kaori / Umeda, Masataka / Yamamoto, Kazuko / Mori, Ryoichi / Kawakami, Atsushi

Clinical immunology (Orlando, Fla.)

2021 Volume 233, Page(s) 108887

Abstract: mTOR signaling may be a new therapeutic target for IL-6 inhibitor refractory iMCD-NOS. ...

Abstract	mTOR signaling may be a new therapeutic target for IL-6 inhibitor refractory iMCD-NOS.
MeSH term(s)	Adult ; Antibodies, Monoclonal, Humanized/therapeutic use ; Castleman Disease/drug therapy ; Humans ; Immunosuppressive Agents/therapeutic use ; Male ; Sirolimus/therapeutic use
Chemical Substances	Antibodies, Monoclonal, Humanized ; Immunosuppressive Agents ; tocilizumab (I031V2H011) ; Sirolimus (W36ZG6FT64)
Language	English
Publishing date	2021-11-16
Publishing country	United States
Document type	Case Reports ; Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	1459903-x
ISSN	1521-7035 ; 1521-6616
ISSN (online)	1521-7035
ISSN	1521-6616
DOI	10.1016/j.clim.2021.108887
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Article ; Online: Nicotinamide Effectively Suppresses Fusarium Head Blight in Wheat Plants.

Sidiq, Yasir / Nakano, Masataka / Mori, Yumi / Yaeno, Takashi / Kimura, Makoto / Nishiuchi, Takumi

International journal of molecular sciences

2021 Volume 22, Issue 6

Abstract: Pyridine nucleotides such as a nicotinamide adenine dinucleotide (NAD) are known as plant defense activators. We previously reported that nicotinamide mononucleotide (NMN) enhanced disease resistance against fungal ... ...

Abstract	Pyridine nucleotides such as a nicotinamide adenine dinucleotide (NAD) are known as plant defense activators. We previously reported that nicotinamide mononucleotide (NMN) enhanced disease resistance against fungal pathogen
MeSH term(s)	Fusarium/drug effects ; Fusarium/metabolism ; Fusarium/pathogenicity ; Niacinamide/pharmacology ; Plant Diseases/microbiology ; Plant Diseases/prevention & control ; Trichothecenes/metabolism ; Triticum/drug effects ; Triticum/microbiology
Chemical Substances	Trichothecenes ; Niacinamide (25X51I8RD4) ; deoxynivalenol (JT37HYP23V)
Language	English
Publishing date	2021-03-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms22062968
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Article: Robot-assisted thoracoscopic resection of a posterior mediastinal tumor with preserving the artery of Adamkiewicz.

Nemoto, Yukiko / Kuroda, Koji / Mori, Masataka / Kanayama, Masatoshi / Kuwata, Tiaji / Takenaka, Masaru / Tanaka, Fumihiro

Surgical case reports

2022 Volume 8, Issue 1, Page(s) 129

Abstract: Background: The artery of Adamkiewicz (AKA) provides the major blood supply to the lower two-thirds of the spinal cord. As the AKA typically arises from a left posterior intercostal artery at the levels between 9 and 12th thoracic vertebrae, injury of ... ...

Abstract	Background: The artery of Adamkiewicz (AKA) provides the major blood supply to the lower two-thirds of the spinal cord. As the AKA typically arises from a left posterior intercostal artery at the levels between 9 and 12th thoracic vertebrae, injury of the AKA during thoracic surgery such as resection of a lower paravertebral tumor may cause serious neurological complications. Robot-assisted thoracic surgery (RATS) has several advantages over video-assisted thoracic surgery including three-dimensional and high-definition view with high image magnification and reduced restriction in movement of surgical instruments. Here, we present a case of a left paravertebral ganglioneuroma originating from the sympathetic trunk. Whereas both tumor-feeding arteries and the AKA arose from the 9 Case presentation: A 15-year-old girl admitted for surgery for a posterior mediastinal tumor. Chest computed tomography showed a well-circumscribed 8.0 cm tumor adjacent to 8-11th thoracic vertebrae and the descending aorta. Contrast-enhanced CT and angiography revealed that the AKA arose from the left 9 Conclusions: RATS is a useful surgical approach for removal of a mediastinal tumor with preserving surrounding organs or tissues, such as the AKA.
Language	English
Publishing date	2022-07-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2809613-7
ISSN	2198-7793
ISSN	2198-7793
DOI	10.1186/s40792-022-01487-6
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Article ; Online: Salvage pleurectomy/decortication following immunotherapy for malignant pleural mesothelioma.

Takenaka, Masaru / Kuroda, Koji / Yoshimatsu, Katsuma / Mori, Masataka / Kanayama, Masatoshi / Taira, Akihiro / Kuwata, Taiji / Tanaka, Fumihiro

Interdisciplinary cardiovascular and thoracic surgery

2023 Volume 38, Issue 2

Abstract: Salvage surgery following immunotherapy is a promising treatment option for advanced malignant tumour. However, only a few cases of salvage surgery for malignant pleural mesothelioma (MPM) have been reported. This retrospective study was conducted to ... ...

Abstract	Salvage surgery following immunotherapy is a promising treatment option for advanced malignant tumour. However, only a few cases of salvage surgery for malignant pleural mesothelioma (MPM) have been reported. This retrospective study was conducted to assess the feasibility of salvage surgery following immunotherapy for initially unresectabele MPM. Among 61 patients who received pleurectomy/decortication (P/D) for MPM, 7 patients received salvage P/D after immunotherapy. Surgical indication of salvage P/D was conversion to resectability in 5 patients and local relapse in 2 patients, and macroscopic complete resection was achieved in all patients. Although salvage P/D was associated with longer operation time (median, 507 min), higher intraoperative blood loss (median, 2573 mL) and higher morbidity (≥ grade 3, 29%), no patient died after surgery. Radiographic response to immunotherapy was well correlated with pathologic response, as all 4 patients with partial response showed significant pathologic response (viable cells, ≤50%). With the median postoperative follow-up duration of 9.0 months, all patients were alive mostly without tumour recurrence as local recurrence developed in 1 patient. To conclude, salvage P/D after immunotherapy may be a feasible treatment option for selected patients with advanced MPM, which should be validated in future multi-institutional studies. In addition, a long-term follow-up is essential to reveal the clinical benefit achieved with salvage P/D following immunotherapy.
Language	English
Publishing date	2023-11-15
Publishing country	England
Document type	Journal Article
ISSN	2753-670X
ISSN (online)	2753-670X
DOI	10.1093/icvts/ivad173
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