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  1. Book ; Online ; Conference proceedings: New Advances in Renal Ammonia Metabolism

    Schoolwerth, A.C.

    3rd International Workshop on Ammoniagenesis, Monterey, Calif., June 1984

    (Contributions to Nephrology ; Vol.47)

    1985  

    Series title Contributions to Nephrology ; Vol.47
    Keywords Biochemistry ; Nephrology ; Physiology ; Biology for Physicians ; Metabolic Diseases ; Metabolism
    Language English
    Size 1 Online-Ressource (X + 238 S.)
    Publisher S. Karger
    Publishing place Basel
    Document type Book ; Online ; Conference proceedings
    HBZ-ID HT019542682
    ISBN 978-3-318-03311-3 ; 3-318-03311-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Conference proceedings: New advances in renal ammonia metabolism

    Schoolwerth, Anton C.

    (Contributions to nephrology ; 47)

    1985  

    Event/congress International Workshop on Ammoniagenesis (3., 1984, MontereyCalif.)
    Author's details 3rd Internat. Workshop on Ammoniagenesis, Monterey, Calif., June 17 - 19, 1984. Vol. eds. A. C. Schoolwerth
    Series title Contributions to nephrology ; 47
    Collection
    Keywords Ammonia / metabolism / congresses ; Kidney / metabolism / congresses ; Ammoniakstoffwechsel ; Niere
    Subject Nephros ; Ren ; Ammoniak
    Size XI, 236 S. : graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    HBZ-ID HT002135406
    ISBN 3-8055-4009-4 ; 978-3-8055-4009-4
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1986 A 71 order for loan Magazin

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  3. Article: Cystinuria: current concepts and future directions.

    Pereira, Daniel J Castro / Schoolwerth, Anton C / Pais, Vernon M

    Clinical nephrology

    2015  Volume 83, Issue 3, Page(s) 138–146

    Abstract: Cystinuria, an autosomic recessive genetic disorder is an uncommon cause of nephrolithiasis characterized by an impairment of transport of cystine, ornithine, lysine, and arginine (COLA). Of these, only cystine is insoluble enough to cause stone ... ...

    Abstract Cystinuria, an autosomic recessive genetic disorder is an uncommon cause of nephrolithiasis characterized by an impairment of transport of cystine, ornithine, lysine, and arginine (COLA). Of these, only cystine is insoluble enough to cause stone formation. Although a classification exists that categorizes the disease depending on chromosomal mutation, this does not currently alter management which consists of increased fluid intake, urine alkalinization, reduced sodium intake and, if warranted, cystine-binding thiol drugs. Cystine stones are relatively resistant to fragmentation. Intrinsic characteristics on imaging may help in planning surgical treatment. Finally, advances in crystal growth inhibition are encouraging as they may provide a new tool to treat this condition which although uncommon, is treatable and has been associated with lower quality of life and renal function compared to other stone formers.
    MeSH term(s) Cystine/metabolism ; Cystinuria/diagnosis ; Cystinuria/epidemiology ; Cystinuria/etiology ; Cystinuria/therapy ; Humans
    Chemical Substances Cystine (48TCX9A1VT)
    Language English
    Publishing date 2015-02-15
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 185101-9
    ISSN 0301-0430
    ISSN 0301-0430
    DOI 10.5414/cn108514
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  4. Article: Acute renal failure: outcomes and risk of chronic kidney disease.

    Block, C A / Schoolwerth, A C

    Minerva urologica e nefrologica = The Italian journal of urology and nephrology

    2007  Volume 59, Issue 3, Page(s) 327–335

    Abstract: Acute renal failure (ARF) is a common condition, especially among the critically ill, and confers a high mortality. The incidence of ARF is increasing. Efforts such as the Acute Dialysis Quality Initiative (ADQI) are being undertaken to establish a ... ...

    Abstract Acute renal failure (ARF) is a common condition, especially among the critically ill, and confers a high mortality. The incidence of ARF is increasing. Efforts such as the Acute Dialysis Quality Initiative (ADQI) are being undertaken to establish a consensus definition of ARF, and to distinguish between varying degrees of acute kidney injury that might confer a different prognosis. Data are emerging to allow comparison of the epidemiology of ARF across institutions internationally. There is ongoing recognition of the important interaction between ARF and chronic kidney disease and more information regarding recovery from ARF is available. Controversy exists regarding the optimal management of ARF. Recent publications emphasize the importance of timing and dose of renal replacement therapy rather than the modality of treatment (intermittent hemodialysis vs continuous therapies). These issues are explored in this review.
    MeSH term(s) Acute Disease ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/epidemiology ; Acute Kidney Injury/etiology ; Humans ; Kidney Diseases/complications ; Prognosis
    Language English
    Publishing date 2007-09
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 632505-1
    ISSN 1827-1758 ; 0393-2249 ; 0026-4989
    ISSN (online) 1827-1758
    ISSN 0393-2249 ; 0026-4989
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  5. Article: The epidemiology and outcome of acute renal failure and the impact on chronic kidney disease.

    Block, Clay A / Schoolwerth, Anton C

    Seminars in dialysis

    2006  Volume 19, Issue 6, Page(s) 450–454

    Abstract: Acute renal failure (ARF) is a common condition, especially among the critically ill, and confers a high mortality. Recent publications have highlighted changes in the epidemiology and improvement in mortality that was long thought to be static despite ... ...

    Abstract Acute renal failure (ARF) is a common condition, especially among the critically ill, and confers a high mortality. Recent publications have highlighted changes in the epidemiology and improvement in mortality that was long thought to be static despite improvements in clinical care. The incidence of ARF is increasing. Efforts, such as the Acute Dialysis Quality Initiative, are being undertaken to establish a consensus definition of ARF, and to distinguish between varying degrees of acute kidney injury. Data are emerging to allow comparison of the epidemiology of ARF across institutions internationally. There is ongoing recognition of the important interaction between ARF and chronic kidney disease. Two brief case reports are offered to help frame the context and clinical impact of this disorder, followed by a review of some of the recent literature that addresses these points.
    MeSH term(s) Acute Kidney Injury/complications ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/epidemiology ; Acute Kidney Injury/therapy ; Aged, 80 and over ; Critical Illness ; Disease Progression ; Fatal Outcome ; Humans ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/etiology ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Renal Replacement Therapy ; Time Factors
    Language English
    Publishing date 2006-11
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1028193-9
    ISSN 1525-139X ; 0894-0959
    ISSN (online) 1525-139X
    ISSN 0894-0959
    DOI 10.1111/j.1525-139X.2006.00206.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Images in clinical medicine. "Maltese crosses" in the nephrotic syndrome.

    Sedlacek, Martin / Schoolwerth, Anton C

    The New England journal of medicine

    2007  Volume 357, Issue 8, Page(s) 806

    MeSH term(s) Aged ; Glomerulonephritis, Membranous/pathology ; Humans ; Male ; Nephrotic Syndrome/pathology ; Proteinuria/pathology ; Urine/chemistry
    Language English
    Publishing date 2007-08-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMicm062919
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  7. Article: Part 1. Uric acid and losartan.

    Sica, Domenic A / Schoolwerth, Anton C

    Current opinion in nephrology and hypertension

    2002  Volume 11, Issue 5, Page(s) 475–482

    Abstract: Purpose of review: To characterize the mechanism and clinical impact of the angiotensin-receptor blocker losartan on both renal uric acid handling and thereby serum uric acid.: Recent findings: Losartan effect on serum uric acid has been demonstrated ...

    Abstract Purpose of review: To characterize the mechanism and clinical impact of the angiotensin-receptor blocker losartan on both renal uric acid handling and thereby serum uric acid.
    Recent findings: Losartan effect on serum uric acid has been demonstrated at various stages of renal failure including most recently observations obtained in end-stage renal disease patients. Other angiotensin-receptor blockers do not alter renal handling of uric acid. The uricosuria, which accompanies losartan administration, has not been associated with adverse renal consequences, in part, because of the increase in urinary pH that follows its administration.
    Summary: Hyperuricemia is closely linked to both hypertension and cardiovascular disease. The development of hyperuricemia and its persistence are clearly renal processes. Likewise, the correction of hyperuricemia is often accomplished by increasing its renal excretion. A number of medications, by way of varying mechanisms, can alter renal urate handling and thereby influence serum uric acid values. Most recently, the angiotensin-receptor blocker losartan has been shown to reduce serum uric acid. The mechanism of this process relates to losartan alone and does not involve the E-3174 metabolite of this compound. This probenecid-like effect of losartan occurs shortly after drug administration, and is both transient and dose-dependent. This property of losartan, touted by some as a meaningful pharmacological distinction among the angiotensin-receptor blockers, remains to be proved, since, to date, the hypothesis that a reduction in serum uric acid alters the natural history of cardiovascular disease has not been formally tested.
    MeSH term(s) Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Animals ; Blood/metabolism ; Humans ; Kidney/metabolism ; Losartan/pharmacology ; Uric Acid/metabolism
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors ; Uric Acid (268B43MJ25) ; Losartan (JMS50MPO89)
    Language English
    Publishing date 2002-09
    Publishing country England
    Document type Editorial ; Review
    ZDB-ID 1151092-4
    ISSN 1535-3842 ; 1062-4821 ; 1062-4813
    ISSN (online) 1535-3842
    ISSN 1062-4821 ; 1062-4813
    DOI 10.1097/00041552-200209000-00001
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  8. Article: Regulation of renal ammoniagenesis in metabolic acidosis.

    Schoolwerth, A C

    Kidney international

    1991  Volume 40, Issue 5, Page(s) 961–973

    MeSH term(s) Acidosis/complications ; Acidosis/metabolism ; Adult ; Ammonia/metabolism ; Anemia, Sickle Cell/complications ; Animals ; Diabetic Ketoacidosis/metabolism ; Humans ; Hydrogen-Ion Concentration ; Ketoglutaric Acids/metabolism ; Kidney/metabolism ; Male
    Chemical Substances Ketoglutaric Acids ; Ammonia (7664-41-7)
    Language English
    Publishing date 1991-11
    Publishing country United States
    Document type Case Reports ; Clinical Conference ; Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1038/ki.1991.301
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    Zs.A 797: Show issues Location:
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  9. Article: Multidisciplinary CKD care enhances outcomes at dialysis initiation.

    Dixon, Judith / Borden, Patricia / Kaneko, Thomas M / Schoolwerth, Anton C

    Nephrology nursing journal : journal of the American Nephrology Nurses' Association

    2011  Volume 38, Issue 2, Page(s) 165–171

    Abstract: In 2003, the Nephrology Section at Dartmouth-Hitchcock Medical Center embraced a new concept for providing care that included a continuing care manager and a nephrologist working together with the patient to introduce stage-based education and clinical ... ...

    Abstract In 2003, the Nephrology Section at Dartmouth-Hitchcock Medical Center embraced a new concept for providing care that included a continuing care manager and a nephrologist working together with the patient to introduce stage-based education and clinical interventions. This study compares the outcomes of patients initiating hemodialysis or peritoneal dialysis who received CKD care using a multidisciplinary care model (n = 89) with those who received traditional nephrology care (n = 82). Overall, the findings in this study support the use of the multidisciplinary clinic as a method for improving care of the patient with CKD initiating dialysis, and reducing hospital admissions and costs. The care coordination provided in the multidisciplinary setting improved the number of fistulas placed (60.7% vs. 21%, p < 0.001), the number of fistulas used for dialysis initiation (40.4% vs. 12.3, p < 0.001), and the management of anemia with higher hemoglobin levels prior to dialysis initiation (10.9 g/dL vs. 10.0 g/dL, p = 0.003). Patients receiving multidisciplinary care were 42% less likely to be admitted to the hospital for dialysis initiation, had significantly fewer days hospitalized (p = 0.001), fewer admissions (p = 0.005), and reduced charges for a 90-day period (p = 0.003) after dialysis initiation.
    MeSH term(s) Humans ; Kidney Failure, Chronic/nursing ; Kidney Failure, Chronic/therapy ; Longitudinal Studies ; Patient Care Team ; Renal Dialysis ; Retrospective Studies
    Language English
    Publishing date 2011-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2008177-7
    ISSN 1526-744X ; 8750-0779
    ISSN 1526-744X ; 8750-0779
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  10. Article: Hematuria and proteinuria: their causes and consequences.

    Schoolwerth, A C

    Hospital practice (Office ed.)

    1987  Volume 22, Issue 10A, Page(s) 45–52, 55–6, 58–62

    MeSH term(s) Adult ; Aged ; Child ; Hematuria/diagnosis ; Hematuria/etiology ; Humans ; Proteinuria/diagnosis ; Proteinuria/etiology
    Language English
    Publishing date 1987-10-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2570453-9
    ISSN 2377-1003 ; 8750-2836 ; 2154-8331
    ISSN (online) 2377-1003
    ISSN 8750-2836 ; 2154-8331
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