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  1. Article ; Online: Tracing proof schemes

    Yasemin Yılmaz Akkurt / Soner Durmuş

    Journal of Research and Advances in Mathematics Education, Vol 7, Iss 1, Pp 1-

    some patterns and new perspectives

    2022  Volume 16

    Abstract: The aim of this paper is to review some studies conducted with different learning areas in which the schemes of different participants emerge. Also it is about to show how mathematical proofs are handled in these studies by considering Harel and Sowder's ...

    Abstract The aim of this paper is to review some studies conducted with different learning areas in which the schemes of different participants emerge. Also it is about to show how mathematical proofs are handled in these studies by considering Harel and Sowder's classification of proof schemes with specific examples. As a result, it was seen that the examined studies were addressed in the learning areas of Analysis, Geometry, Algebra, Linear Algebra, Elementary Number Theory, Probability, Combinatorics, and MIX. Students in early grades tend more towards external and empirical proof schemes. On the other hand, the characteristics of the proof schemes become more sophisticated as the participants' profiles change to pre-service teachers or as they become more specializing in mathematics. Some results are as follows: the academic achievement levels, genders, and grade levels of the participants in the studies examined in this paper have indicated that they have similar traces with the schemes they use. In addition, it has been determined that new perspectives such as examining Harel and Sowder's classification with new lenses, revealing the overlooked roles of some dynamics in proof, or improving the framework provide an important research area in terms of revealing students' potentials.
    Keywords proof ; proving process ; proof schemes ; learning areas ; Education (General) ; L7-991 ; Science ; Q ; Mathematics ; QA1-939
    Subject code 370
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Muhammadiyah University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Stabilization of Rice Bran: A Review.

    Yılmaz Tuncel, Neşe

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 9

    Abstract: ... bran emerge as the main by-product of rice grain milling. Usually, rice bran is used as animal feed or ... with considerable health benefits, the rapid deterioration of bran limits the exploitation of the full potential ... of rice bran. Hydrolytic rancidity is the main obstacle to using rice bran as food, and the enzyme ...

    Abstract One of the major problems in food science is meeting the demand of the world's growing population, despite environmental limitations such as climate change, water scarcity, land degradation, marine pollution, and desertification. Preventing food from going to waste and utilizing nutritive by-products as food rather than feed are easy and powerful strategies for overcoming this problem. Rice is an important staple food crop for more than half of the world's population and substantial quantities of rice bran emerge as the main by-product of rice grain milling. Usually, rice bran is used as animal feed or discarded as waste. Although it is highly nutritious and comprises many bioactive compounds with considerable health benefits, the rapid deterioration of bran limits the exploitation of the full potential of rice bran. Hydrolytic rancidity is the main obstacle to using rice bran as food, and the enzyme inactivation process, which is termed stabilization, is the only way to prevent it. This study reviews the methods of stabilizing rice bran and other rice-milling by-products comprising rice bran in the context of the efficiency of the process upon storage. The effect of the process on the components of rice bran is also discussed.
    Language English
    Publishing date 2023-05-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12091924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Point-of-care testing: a disposable label-free electrochemical CA125 and HE4 immunosensors for early detection of ovarian cancer.

    Bilgi Kamaç, Melike / Altun, Muhammed / Yılmaz, Merve / Yılmaz Aktan, Ayla / Aktan, Soner / Sezgintürk, Mustafa Kemal

    Biomedical microdevices

    2023  Volume 25, Issue 2, Page(s) 18

    Abstract: Cancer antigen 125 (CA125) and human epididymal secretory protein 4 (HE4) are critical biomarkers for ovarian cancer diagnosis and progression monitoring; therefore, sensitive determination of their levels in body fluids is crucial. In recent study, ... ...

    Abstract Cancer antigen 125 (CA125) and human epididymal secretory protein 4 (HE4) are critical biomarkers for ovarian cancer diagnosis and progression monitoring; therefore, sensitive determination of their levels in body fluids is crucial. In recent study, label-free CA125 and HE4 immunosensors were prepared using disposable screen-printed carbon electrodes modified with reduced graphene oxide, polythionine, and gold nanoparticles for the sensitive, fast, and practical determination of CA125 and HE4. Differential pulse voltammetry, square wave voltammetry, and electrochemical impedance spectroscopy methods were used for the electrochemical determination of antigens in four different linear ranges (1-100 pg mL
    MeSH term(s) Female ; Humans ; CA-125 Antigen ; Proteins ; Point-of-Care Systems ; Biosensing Techniques ; Gold ; Biomarkers, Tumor ; Immunoassay ; Metal Nanoparticles ; Early Detection of Cancer ; Ovarian Neoplasms/diagnosis ; Ovarian Neoplasms/pathology
    Chemical Substances CA-125 Antigen ; Proteins ; Gold (7440-57-5) ; Biomarkers, Tumor
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2004019-2
    ISSN 1572-8781 ; 1387-2176
    ISSN (online) 1572-8781
    ISSN 1387-2176
    DOI 10.1007/s10544-023-00659-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Enablers and Barriers of Blended Learning in Faculty Development.

    Yilmaz, Yusuf / Durak, Halil Ibrahim / Yildirim, Soner

    Cureus

    2022  Volume 14, Issue 3, Page(s) e22853

    Abstract: Introduction Online learning provides a ubiquitous and self-paced learning experience, while face-to-face learning encourages commitment in a prescheduled formal instruction. Blended learning (BL) combines these two mediums and provides flexible learning ...

    Abstract Introduction Online learning provides a ubiquitous and self-paced learning experience, while face-to-face learning encourages commitment in a prescheduled formal instruction. Blended learning (BL) combines these two mediums and provides flexible learning opportunities. While faculty development programs have utilized these two mediums separately, BL has not been fully implemented locally until recently. Identifying elements that enable or hinder faculty within a newly implemented BL program can enhance the learning experience and support professional development. The current study aims to identify how junior and senior faculty members of medical departments at a Turkish university perceive enablers and barriers in a new BL faculty development program. Methods This research is a multiple case study with qualitative inquiry using in-depth interviews and thematic analysis. Using a BL approach, the research team designed faculty development activities based on the Four-Component Instructional Design model. Participants accessed the activities on a Moodle learning management system. Faculty experiences in blended faculty development were examined. The study group consisted of 26 participants, with 14 junior faculty in case 1 and 12 senior faculty in case 2 from different medical departments at a Turkish university. Data were collected and analyzed using qualitative methods. Results This study identified enablers and barriers within a BL faculty development program. While participants identified three barriers, they identified eight enabling elements in a BL program. A lack of time was the most critical barrier to participation in the program. Setting goals for personal development and obtaining skills in teaching were essential enablers within the BL program. Conclusion The use of an online platform to support face-to-face faculty development programs is beneficial in several ways for faculty. Faculty developers can utilize BL to foster engagement and motivate faculty for increased participation, especially if they seek to mitigate known barriers to a successful BL program. Online communication and activities are suggested to develop communities of practice in the workplace. Strategies to eliminate workload and provide guidance on time management are required for both junior and senior faculty.
    Language English
    Publishing date 2022-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.22853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The effect of a seed coating with Origanum vulgare essential oil on Clavibacter michiganensis subsp. michiganensis

    Yılmaz, Meral / Baysal, Ömür / Silme, Ragıp Soner

    Plant Protection Science. , v. 57, no. 3

    2021  

    Abstract: The study aimed to evaluate the efficacy of a seed film coating with Origanum vulgare Linnaeus essential oil (EO) against Clavibacter michiganensis subsp. michiganensis (Cmm) on tomatoes. Tomato seeds (cv. Rio Grande) coated with different doses of EO ... ...

    Abstract The study aimed to evaluate the efficacy of a seed film coating with Origanum vulgare Linnaeus essential oil (EO) against Clavibacter michiganensis subsp. michiganensis (Cmm) on tomatoes. Tomato seeds (cv. Rio Grande) coated with different doses of EO derived from O. vulgare were inoculated with Cmm (1.8 × 10<sup>8</sup> CFU/mL). O. vulgare's EO showed a remarkable inhibition effect on the Cmm growth. The EO effect against Cmm was determined based on the parameters, such as the inhibition zone and bacterial population in a seed. The GC-MS analysis of EO showed that carvacrol is the major component (at 74.05%), which may inhibit the bacterial growth. Later, we have expanded our studies to determine the inhibitory effect of the EO's mode of action on the pathogenic bacteria with a molecular docking analysis based on the molecular protein-ligand interaction. The results showed that carvacrol has a strong interaction with the bacterial expansin protein (PDB 4JJO) of Cmm and the qPCR analyses confirmed the effect of the O. vulgare treatment against Cmm. This original approach has the prominent potential to prevent seed transmission of Cmm for seed quality in the world, suggesting a method for paving the way for Cmm disease management.
    Keywords Clavibacter michiganensis subsp. michiganensis ; Origanum vulgare ; bacterial growth ; carvacrol ; disease control ; essential oils ; mechanism of action ; plant protection ; seed quality ; tomatoes
    Language English
    Dates of publication 2021-0610
    Size p. 217-225.
    Publishing place Czech Academy of Agricultural Sciences
    Document type Article
    ZDB-ID 1426641-6
    ISSN 0862-8645 ; 1212-2580
    ISSN 0862-8645 ; 1212-2580
    DOI 10.17221/177/2020-pps
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Effectiveness of Vapocoolant Spray on Venipuncture Pain in Young Male Donors: A Randomized Controlled Trial.

    Basak, Tulay / Aciksoz, Semra / Savasci, Umit / Yilmaz, Soner

    Journal of infusion nursing : the official publication of the Infusion Nurses Society

    2021  Volume 44, Issue 6, Page(s) 339–345

    Abstract: The aim of this single-blinded, randomized controlled study was to determine the effectiveness of vapocoolant spray in reducing pain related to venipuncture in young, healthy male blood donors. The participants were separated into 2 groups by ... ...

    Abstract The aim of this single-blinded, randomized controlled study was to determine the effectiveness of vapocoolant spray in reducing pain related to venipuncture in young, healthy male blood donors. The participants were separated into 2 groups by randomization. The donors in the control group (n = 44) were not given any intervention during the blood collection process. Vapocoolant spray was applied to the donors in the vapocoolant spray group (n = 44). The pain score was 1.90 ± 1.47 for the vapocoolant spray group and 3.23 ± 2.21 for the control group, and the difference between the groups was found to be statistically significant (P = .02). The study result showed that the use of vapocoolant spray for pain management is an effective method of reducing pain related to venipuncture during the process of blood donation in young male donors.
    MeSH term(s) Anesthetics, Local ; Humans ; Male ; Pain/etiology ; Pain/prevention & control ; Pain Management ; Pain Measurement ; Phlebotomy ; Research Design
    Chemical Substances Anesthetics, Local
    Language English
    Publishing date 2021-11-10
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2192558-6
    ISSN 1539-0667 ; 1533-1458
    ISSN (online) 1539-0667
    ISSN 1533-1458
    DOI 10.1097/NAN.0000000000000443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: LEPTIN RECEPTORS EXPRESSION IN MAMMARY TUMORS AND MAMMARY FAT PAD OF TRANSGENIC MAMMARY CANCER MOUSE MODEL.

    Yilmaz, Elif / Thomas, Pinar / Tuna, Bilge / Cleary, Margot / Dogan, Soner

    Experimental oncology

    2022  Volume 44, Issue 4, Page(s) 272–280

    Abstract: Background: Leptin is an adipokine encoded by the Ob (obese) gene and predominantly produced by adipocytes. The roles of both leptin and leptin receptor (ObR) in numerous pathophysiological conditions including mammary tumor (MT) development have been ... ...

    Abstract Background: Leptin is an adipokine encoded by the Ob (obese) gene and predominantly produced by adipocytes. The roles of both leptin and leptin receptor (ObR) in numerous pathophysiological conditions including mammary tumor (MT) development have been reported.
    Aim: To examine protein expression levels of leptin and its receptors (ObR) including the long form, ObRb, in MT tissue and mammary fat pad of a transgenic mammary cancer mouse model. Further, we investigated whether the effects of leptin on MT development are systemic or local.
    Materials and methods: MMTV-TGF-α transgenic female mice were fed ad libitum from week 10 up to week 74. Protein expression levels of leptin, ObR, and ObRb were measured in the mammary tissue samples of 74-week old MMTV-TGF-α mice with and without MT (MT-positive/MT-negative) by Western blot analysis. Serum leptin levels were measured by using the mouse adipokine LINCOplex kit 96-well plate assay.
    Results: Protein expression levels of ObRb were significantly lower in MT as compared to control tissue of mammary gland. In addition, protein expression levels of leptin were significantly higher in the MT tissue of MT-positive mice compared to control tissue of MT-negative mice. However, ObR protein expression levels in tissues of mice with and without MT were similar. Serum leptin levels at different ages were not significantly different between the two groups.
    Conclusion: Leptin and ObRb in the mammary tissue may play a critical role in the mammary cancer development, while contribution of short ObR isoform may be less important.
    MeSH term(s) Animals ; Mice ; Female ; Leptin/genetics ; Leptin/metabolism ; Mice, Transgenic ; Receptors, Leptin ; Transforming Growth Factor alpha/genetics ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/metabolism ; Mammary Neoplasms, Experimental/pathology ; Adipose Tissue/metabolism
    Chemical Substances Leptin ; Receptors, Leptin ; Transforming Growth Factor alpha
    Language English
    Publishing date 2022-10-29
    Publishing country Ukraine
    Document type Journal Article
    ZDB-ID 2176927-8
    ISSN 1812-9269 ; 0204-3564
    ISSN 1812-9269 ; 0204-3564
    DOI 10.32471/exp-oncology.2312-8852.vol-44-no-4.18941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Four novel Myxobolus species (Cnidaria: Myxozoa) infecting Anatolian khramulya Capoeta tinca (Cyprinidae) in northern Turkey.

    Zafer Pekmezci, Gokmen / Yardimci, Banu / Soner Bolukbas, Cenk / Yilmaz, Savas / Polat, Nazmi

    Diseases of aquatic organisms

    2021  Volume 144, Page(s) 41–54

    Abstract: We identified Myxobolus anatolicus Pekmezci, Yardimci, Yilmaz & Polat, 2014 and 4 novel Myxobolus ...

    Abstract We identified Myxobolus anatolicus Pekmezci, Yardimci, Yilmaz & Polat, 2014 and 4 novel Myxobolus species from the Anatolian khramulya Capoeta tinca (Cyprinidae) in northern Turkey based on morphology, histology, and phylogenetic analysis. M. karaeri sp. nov. plasmodia were observed in the skin doublets between fin rays, the surfaces of the operculum, the gill arch membrane, and in the skin of the fin base. M. samsunensis sp. nov. plasmodia were observed in epithelial tissue inside and on the surface and midline of the gill filaments. M. cakmaki sp. nov. presented as a typical vascular species, which develops in large plasmodia at the end of the gill filaments. The chondrophilic M. ekingeni sp. nov. was detected by histology inside the cartilaginous gill arch and the cartilaginous gill rays of the filaments. Phylogenetic analysis of small subunit ribosomal DNA sequences revealed that M. karaeri sp. nov. and M. samsunensis sp. nov. were clustered with Myxobolus species that infect gills, scales, and fins of cyprinids. M. cakmaki sp. nov. grouped with Myxobolus species that exclusively infect the gills of cyprinids. No molecular data were available for M. ekingeni sp. nov.
    MeSH term(s) Animals ; Cnidaria ; Cyprinidae ; DNA, Ribosomal ; Fish Diseases/epidemiology ; Gills ; Myxobolus/genetics ; Myxozoa/genetics ; Parasitic Diseases, Animal ; Phylogeny ; Turkey
    Chemical Substances DNA, Ribosomal
    Language English
    Publishing date 2021-03-11
    Publishing country Germany
    Document type Journal Article
    ISSN 0177-5103
    ISSN 0177-5103
    DOI 10.3354/dao03573
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Stabilization of Rice Bran: A Review

    Yılmaz Tuncel, Neşe

    Foods. 2023 May 08, v. 12, no. 9

    2023  

    Abstract: ... bran emerge as the main by-product of rice grain milling. Usually, rice bran is used as animal feed or ... with considerable health benefits, the rapid deterioration of bran limits the exploitation of the full potential ... of rice bran. Hydrolytic rancidity is the main obstacle to using rice bran as food, and the enzyme ...

    Abstract One of the major problems in food science is meeting the demand of the world’s growing population, despite environmental limitations such as climate change, water scarcity, land degradation, marine pollution, and desertification. Preventing food from going to waste and utilizing nutritive by-products as food rather than feed are easy and powerful strategies for overcoming this problem. Rice is an important staple food crop for more than half of the world’s population and substantial quantities of rice bran emerge as the main by-product of rice grain milling. Usually, rice bran is used as animal feed or discarded as waste. Although it is highly nutritious and comprises many bioactive compounds with considerable health benefits, the rapid deterioration of bran limits the exploitation of the full potential of rice bran. Hydrolytic rancidity is the main obstacle to using rice bran as food, and the enzyme inactivation process, which is termed stabilization, is the only way to prevent it. This study reviews the methods of stabilizing rice bran and other rice-milling by-products comprising rice bran in the context of the efficiency of the process upon storage. The effect of the process on the components of rice bran is also discussed.
    Keywords climate change ; desertification ; enzyme inactivation ; feeds ; food science ; land degradation ; marine pollution ; rancidity ; rice ; rice bran ; staple crops ; wastes ; water shortages
    Language English
    Dates of publication 2023-0508
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12091924
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Effect of SOD-Rich Melon Supplement on Performance, Serum Biochemical, Antioxidant and Meat Quality Characteristics of Tuj Lambs

    Mükremin Ölmez / Roshan Riaz / Özlem Karadağoğlu / Tarkan Şahin / İdil Şerbetçi / Benian Yılmaz / Soner Uysal / Mehmet Akif Yörük

    Agriculture, Vol 13, Iss 625, p

    2023  Volume 625

    Abstract: The present study aimed to evaluate the effects of SOD (superoxide dismutase)-rich melon feed supplement on some performance parameters, serum biochemical and antioxidant indexes, and meat quality characteristics of weaned Tuj lambs. An independent ... ...

    Abstract The present study aimed to evaluate the effects of SOD (superoxide dismutase)-rich melon feed supplement on some performance parameters, serum biochemical and antioxidant indexes, and meat quality characteristics of weaned Tuj lambs. An independent measures design (between groups) was used to determine these effects of treatment. After one week of the adaptation period, twenty-four weaned lambs at the age of 60 ± 5.0 days with a body weight of 23.14 ± 0.5 kg were divided into two groups, i.e., the control group (CON) fed basal diet and experimental group (EXP) fed with basal diet + SOD-rich melon ( n = 12 per group). The results revealed a decrement in the ( p < 0.05) feed efficiency ratio (5.88 ± 0.40 vs. 6.59 ± 0.86 kg weight gain/kg feed) and higher carcass yield (61.76 ± 0.80 vs. 60.11 ± 1.07%) in the EXP group as compared to the CON group. Additionally, the EXP group showed a significant increase ( p < 0.05) in serum glucose and high-density lipoprotein levels, while there was a reduction in cholesterol, triglyceride, and low-density lipoprotein levels when compared to the CON group. The serum malondialdehyde was lowered (5.53 ± 0.47 vs. 5.98 ± 0.79 mmol/L) significantly ( p < 0.05), while glutathione concentration was higher ( p < 0.05) in the EXP group (17.82 ± 1.51 mmol/L) when compared to the CON group (16.54 ± 1.59 mmol/L). The cooking loss was also significantly ( p < 0.05) lower in the EXP group when compared to the CON group. In conclusion, the results indicate that SOD-rich melon supplement (30 g/ton of the concentrate feed) can considerably improve carcass yield, some serum biochemical parameters, and meat quality characteristics in Tuj lambs. Thus, the supplementation of lamb diets with a SOD-rich melon additive may be used as an effective nutritional approach to improve their performance and health.
    Keywords SOD-rich melon feed ; Tuj sheep ; feed additives ; antioxidants ; Agriculture (General) ; S1-972
    Subject code 630
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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