LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 537

Search options

  1. Article ; Online: Heartwatch: an Irish cardiovascular secondary prevention programme in primary care, a secondary analysis of patient outcomes.

    Homeniuk, Robyn / Stanley, Fintan / Gallagher, Joseph / Collins, Claire

    BMJ open

    2023  Volume 13, Issue 1, Page(s) e063811

    Abstract: Objectives: To investigate patient follow-up data from Heartwatch: Ireland's secondary prevention programme for cardiovascular disease delivered in general practice.: Design: Retrospective descriptive study based on secondary analysis of routinely ... ...

    Abstract Objectives: To investigate patient follow-up data from Heartwatch: Ireland's secondary prevention programme for cardiovascular disease delivered in general practice.
    Design: Retrospective descriptive study based on secondary analysis of routinely collected data from Heartwatch.
    Setting: Heartwatch targeted 20% of general practices in Ireland and recruited 475 general practitioners across 325 practices.
    Participants: The patient population included people with a history of acute myocardial infarction, percutaneous transluminal coronary angioplasty or a coronary artery bypass graft. Over 16 000 patients entered the programme however, to assess the long-term progress of patients, we identified a cohort of 5700 patients with at least 8 years in the programme.
    Interventions: A standard protocol for continuing care of patients for the secondary prevention of cardiovascular disease was administered by general practices. The programme was designed using WHO and European Society of Cardiology guidelines on secondary prevention.
    Outcome measures: A Continuing Care (CCare) score out of eight was the primary outcome measure used. It was calculated based on programme targets for well-known cardiovascular risk factors: exercise, systolic blood pressure, LDL cholesterol, optimally controlled glucose, smoking status, and pharmacological treatment.
    Results: After 1 year, 37% of the 8-year cohort had achieved a CCare score >5 increasing to 44% after year 8. Patient sex was predictive of better scores; male patients had almost a half-point advantage (0.432, 99% CI: 0.335 to 0.509). Patients who enrolled earlier following their qualifying event and patients with more frequent visits were also more likely to achieve higher CCare scores.
    Conclusions: Overall, patients are not likely to meet all targets set by secondary prevention guidelines, however, supporting patient self-management may impact on this. Early enrolment after a cardiac event and frequent structured care visits should be priorities in the design and implementation of similar programmes. Ongoing evaluation of them is necessary to improve outcomes.
    MeSH term(s) Humans ; Male ; Secondary Prevention/methods ; Retrospective Studies ; Smoking/adverse effects ; Myocardial Infarction ; Primary Health Care
    Language English
    Publishing date 2023-01-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-063811
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Centring the health of women across the HIV research continuum.

    Barr, Elizabeth / Marshall, Leslie J / Collins, Lauren F / Godfrey, Catherine / St Vil, Noelle / Stockman, Jamila K / Davey, Dvora L Joseph / Dong, Krista / Temkin, Sarah M / Glenshaw, Mary T / Byrd, Corette / Clayton, Janine A / Goodenow, Maureen M

    The lancet. HIV

    2024  Volume 11, Issue 3, Page(s) e186–e194

    Abstract: Despite tremendous advances in HIV research, women and gender diverse people-particularly women from racial and ethnic groups under-represented in research, transgender women, and young women-remain disproportionately affected by HIV. Women and gender ... ...

    Abstract Despite tremendous advances in HIV research, women and gender diverse people-particularly women from racial and ethnic groups under-represented in research, transgender women, and young women-remain disproportionately affected by HIV. Women and gender diverse people face unique challenges and have been under-represented in HIV research. The National Institutes of Health (NIH) is tasked to apply fundamental knowledge about the nature and behaviour of living systems to enhance health, lengthen life, and reduce disability. Rigorous exploration of-and interventions for-the individual, social, biological, structural, and environmental factors that influence HIV prevention, transmission, treatment, and cure is crucial to advance research for women, girls, and gender diverse people across the lifespan. In this Position Paper, we introduce a framework for an intersectional, equity-informed, data-driven approach to research on HIV and women and highlight selected issues for women and gender diverse people, including HIV prevention, HIV cure, ageing with HIV, substance use and misuse, violence, pregnancy, and breastfeeding or chestfeeding. This framework underlines a new HIV and Women Signature Programme from the NIH Office of AIDS Research and Office of Research on Women's Health that advances the NIH vision for women's health, in which all women receive evidence-based HIV prevention, treatment, and care across their lifespan tailored to their unique needs, circumstances, and goals. The time is now to centre the health of women, girls, and gender diverse people across the HIV research continuum.
    MeSH term(s) Humans ; Female ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Acquired Immunodeficiency Syndrome ; Women's Health ; Gender Identity ; Violence
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2352-3018
    ISSN (online) 2352-3018
    DOI 10.1016/S2352-3018(24)00004-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Dual energy computed tomography cannot effectively differentiate between calcium pyrophosphate and basic calcium phosphate diseases in the clinical setting.

    Jarraya, Mohamed / Bitoun, Olivier / Wu, Dufan / Balza, Rene / Guermazi, Ali / Collins, Jamie / Gupta, Rajiv / Nielsen, Gunnlaugur Petur / Guermazi, Elias / Simeone, F Joseph / Omoumi, Patrick / Melnic, Christopher M / Yee, Seonghwan

    Osteoarthritis and cartilage open

    2024  Volume 6, Issue 1, Page(s) 100436

    Abstract: Background: Recent reports suggested that dual-energy CT (DECT) may help discriminate between different types of calcium phosphate crystals : Purpose: Our aim was to test the hypothesis that DECT can effectively differentiate basic calcium phosphate ( ...

    Abstract Background: Recent reports suggested that dual-energy CT (DECT) may help discriminate between different types of calcium phosphate crystals
    Purpose: Our aim was to test the hypothesis that DECT can effectively differentiate basic calcium phosphate (BCP) from calcium pyrophosphate (CPP) deposition diseases.
    Methods: Discarded tissue after total knee replacement specimens in a 71 year-old patient with knee osteoarthritis and chondrocalcinosis was scanned using DECT at standard clinical parameters. Specimens were then examined on light microscopy which revealed CPP deposition in 4 specimens (medial femoral condyle, lateral tibial plateau and both menisci) without BCP deposition. Regions of interest were placed on post-processed CT images using Rho/Z maps (Syngo.via, Siemens Healthineers, VB10B) in different areas of CPP deposition, trabecular bone BCP (T-BCP) and subchondral bone plate BCP (C-BCP).
    Results: Dual Energy Index (DEI) of CPP was 0.12 (SD ​= ​0.02) for reader 1 and 0.09 (SD ​= ​0.03) for reader 2, The effective atomic number (Z
    Conclusion: Differentiation of different types of calcium crystals using DECT is not feasible in a clinical setting.
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ISSN 2665-9131
    ISSN (online) 2665-9131
    DOI 10.1016/j.ocarto.2024.100436
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Just How Confident Can We Be in Predicting Sports Injuries? A Systematic Review of the Methodological Conduct and Performance of Existing Musculoskeletal Injury Prediction Models in Sport.

    Bullock, Garrett S / Mylott, Joseph / Hughes, Tom / Nicholson, Kristen F / Riley, Richard D / Collins, Gary S

    Sports medicine (Auckland, N.Z.)

    2022  Volume 52, Issue 10, Page(s) 2469–2482

    Abstract: Background: An increasing number of musculoskeletal injury prediction models are being developed and implemented in sports medicine. Prediction model quality needs to be evaluated so clinicians can be informed of their potential usefulness.: Objective! ...

    Abstract Background: An increasing number of musculoskeletal injury prediction models are being developed and implemented in sports medicine. Prediction model quality needs to be evaluated so clinicians can be informed of their potential usefulness.
    Objective: To evaluate the methodological conduct and completeness of reporting of musculoskeletal injury prediction models in sport.
    Methods: A systematic review was performed from inception to June 2021. Studies were included if they: (1) predicted sport injury; (2) used regression, machine learning, or deep learning models; (3) were written in English; (4) were peer reviewed.
    Results: Thirty studies (204 models) were included; 60% of studies utilized only regression methods, 13% only machine learning, and 27% both regression and machine learning approaches. All studies developed a prediction model and no studies externally validated a prediction model. Two percent of models (7% of studies) were low risk of bias and 98% of models (93% of studies) were high or unclear risk of bias. Three studies (10%) performed an a priori sample size calculation; 14 (47%) performed internal validation. Nineteen studies (63%) reported discrimination and two (7%) reported calibration. Four studies (13%) reported model equations for statistical predictions and no machine learning studies reported code or hyperparameters.
    Conclusion: Existing sport musculoskeletal injury prediction models were poorly developed and have a high risk of bias. No models could be recommended for use in practice. The majority of models were developed with small sample sizes, had inadequate assessment of model performance, and were poorly reported. To create clinically useful sports musculoskeletal injury prediction models, considerable improvements in methodology and reporting are urgently required.
    MeSH term(s) Athletic Injuries ; Bias ; Humans ; Musculoskeletal System ; Sports
    Language English
    Publishing date 2022-06-11
    Publishing country New Zealand
    Document type Systematic Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-022-01698-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: A Comparative Study of Lymphatic Filariasis-Related Perceptions among Treated and Non-Treated Individuals in the Ahanta West Municipality of Ghana.

    Ahorlu, Collins Stephen / Otchere, Joseph / Sedzro, Kojo M / Pi-Bansa, Sellase / Asemanyi-Mensah, Kofi / Opare, Joseph L / Alomatu, Bright / Long, Elizabeth F / de Souza, Dziedzom K

    Tropical medicine and infectious disease

    2022  Volume 7, Issue 10

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-09-28
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed7100273
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Genetic mapping of host resistance to soybean sudden death syndrome

    Collins, Paul Joseph / Tan, Ruijuan / Wen, Zixiang / Boyse, John F. / Chilvers, Martin I. / Wang, Dechun

    Crop science. 2022 Mar., v. 62, no. 2

    2022  

    Abstract: Soybean sudden death syndrome (SDS) is a disease caused by a soil‐borne fungus, Fusarium virguliforme. Many genetic studies have attempted to identify genes responsible for the quantitative host resistance to SDS. Three recombinant inbred line (RIL) ... ...

    Abstract Soybean sudden death syndrome (SDS) is a disease caused by a soil‐borne fungus, Fusarium virguliforme. Many genetic studies have attempted to identify genes responsible for the quantitative host resistance to SDS. Three recombinant inbred line (RIL) populations were evaluated for foliar SDS resistance at a naturally infested field site in Decatur, MI, during the 2014 and 2015 growing seasons. Lines were evaluated for disease severity (DS) on a 1–9 scale, disease incidence (DI) as an estimate of the percentage of plants with symptoms per plot, and disease index (DX) as a metric which integrates DS and DI. Phenotypic data was spatially adjusted to account for uneven pathogen distribution in the naturally infested field. A subset of RILs from each population were genotyped with the SoySNP6K Illumina Infinium BeadChip. Linkage maps unique to each population were constructed using JoinMap ver. 2. Composite interval mapping was performed using WinQTLCartographer ver. 2.5. Three quantitative trait loci (QTL) were identified across 2 yr and/or multiple populations. One QTL on Chromosome 10 appeared to be colocalized with the E2 maturity locus. Another QTL identified was on Chromosome 18, in a region which has been demonstrated to provide soybean cyst nematode (SCN) and SDS resistance in many studies (rhg1/Rfs2).
    Keywords Fusarium virguliforme ; Heterodera glycines ; disease incidence ; disease severity ; genotyping ; inbred lines ; loci ; pathogens ; phenotype ; quantitative traits ; soil fungi ; soybean sudden death syndrome
    Language English
    Dates of publication 2022-03
    Size p. 713-727.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 410209-5
    ISSN 0011-183X
    ISSN 0011-183X
    DOI 10.1002/csc2.20689
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Book: Meat hygiene

    Gracey, Joseph F. / Collins, D. S.

    1992  

    Author's details J. F. Gracey ; D. S. Collins
    Size X, 549 S. : Ill., graph. Darst.
    Edition 9. ed.y
    Publisher Tindall
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT004944525
    ISBN 0-7020-1495-8 ; 978-0-7020-1495-6
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

    More links

    Kategorien

  8. Book: Meat hygiene

    Gracey, Joseph F. / Collins, D. S. / Huey, Robert J.

    1999  

    Author's details J. F. Gracey ; D. S. Collins ; R. J. Huey
    Keywords Fleischhygiene
    Language English
    Size 758 S. : Ill., graph. Darst.
    Edition 10. ed.
    Publisher Saunders
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012774078
    ISBN 0-7020-2258-6 ; 978-0-7020-2258-6
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

    More links

    Kategorien

  9. Article ; Online: Diagnosis of Hypersensitivity Pneumonitis in Adults, 2020 Clinical Practice Guideline: Summary for Clinicians.

    Koster, Megan A / Thomson, Carey C / Collins, Bridget F / Jenkins, Alex R / Ruminjo, Joseph K / Raghu, Ganesh

    Annals of the American Thoracic Society

    2020  Volume 18, Issue 4, Page(s) 559–566

    MeSH term(s) Adult ; Alveolitis, Extrinsic Allergic/diagnosis ; Alveolitis, Extrinsic Allergic/therapy ; Diagnosis, Differential ; Humans
    Language English
    Publishing date 2020-12-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202009-1195CME
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: A patchy continuum? Stream processes show varied responses to patch- and continuum-based analyses.

    Collins, Sean E / Matter, Stephen F / Buffam, Ishi / Flotemersch, Joseph E

    Ecosphere (Washington, D.C)

    2018  Volume 9, Issue 11

    Abstract: Many conceptual syntheses in ecology and evolution are undergirded by either a patch- or continuum-based model. Examples include gradualism and punctuated equilibrium in evolution, and edge effects and the theory of island biogeography in ecology. In ... ...

    Abstract Many conceptual syntheses in ecology and evolution are undergirded by either a patch- or continuum-based model. Examples include gradualism and punctuated equilibrium in evolution, and edge effects and the theory of island biogeography in ecology. In this study, we sought to determine how patch- or continuum-based analyses could explain variation in concentrations of stream macronutrients and system metabolism, represented by measures of productivity and respiration rates, at the watershed scale across the Kanawha River Basin, USA. Using Strahler stream order (SSO; continuum) and functional process zone (FPZ; patch) as factors, we produced statistical models for each variable and compared model performance using likelihood ratio tests. Only one nutrient (i.e.,
    Language English
    Publishing date 2018-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2572257-8
    ISSN 2150-8925
    ISSN 2150-8925
    DOI 10.1002/ecs2.2481
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top