LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 43

Search options

  1. Article ; Online: Tools for Evaluating the Quality of Life of the Paediatric Population with Primary Headaches-A Review of Selected Questionnaires.

    Rożniecka, Adrianna / Minarowska, Alina

    International journal of environmental research and public health

    2022  Volume 19, Issue 10

    Abstract: Primary headaches are a common health issue in the paediatric population. These conditions have a negative impact on the quality of life of patients at the development age in every area of their lives. The aim of this study is to list the tools used to ... ...

    Abstract Primary headaches are a common health issue in the paediatric population. These conditions have a negative impact on the quality of life of patients at the development age in every area of their lives. The aim of this study is to list the tools used to evaluate the quality of life of the paediatric population with primary headaches and to discuss their advantages and limitations. Examining the quality of life of children and adolescents suffering from primary headaches is of particular importance. This is a consequence of a high disease incidence rate and a considerable negative impact of the ailment on the everyday life of this population. It is very important to conduct such examinations with specific and validated tools. It is significant because of the particular features of the areas of patients' lives at the developmental age. Each of the available questionnaires has specific characteristics, advantages and limitations. The data accumulated in this literature review can be of help in designing research on the quality of life of children and adolescents suffering from primary headaches.
    MeSH term(s) Adolescent ; Child ; Headache/epidemiology ; Humans ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2022-05-22
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19106295
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Tools for Evaluating the Quality of Life of the Paediatric Population with Primary Headaches—A Review of Selected Questionnaires

    Adrianna Rożniecka / Alina Minarowska

    International Journal of Environmental Research and Public Health, Vol 19, Iss 6295, p

    2022  Volume 6295

    Abstract: Primary headaches are a common health issue in the paediatric population. These conditions have a negative impact on the quality of life of patients at the development age in every area of their lives. The aim of this study is to list the tools used to ... ...

    Abstract Primary headaches are a common health issue in the paediatric population. These conditions have a negative impact on the quality of life of patients at the development age in every area of their lives. The aim of this study is to list the tools used to evaluate the quality of life of the paediatric population with primary headaches and to discuss their advantages and limitations. Examining the quality of life of children and adolescents suffering from primary headaches is of particular importance. This is a consequence of a high disease incidence rate and a considerable negative impact of the ailment on the everyday life of this population. It is very important to conduct such examinations with specific and validated tools. It is significant because of the particular features of the areas of patients’ lives at the developmental age. Each of the available questionnaires has specific characteristics, advantages and limitations. The data accumulated in this literature review can be of help in designing research on the quality of life of children and adolescents suffering from primary headaches.
    Keywords paediatric headache ; quality of life questionnaire ; primary headache ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: The Effect of Neoglandin on the Activity of N-Acetyl-β-D-Hexosaminidase in the Serum and Urine of Alcohol-Dependent Men.

    Szajda, Sławomir Dariusz / Dobryniewski, Jacek / Minarowska, Alina / Snarska, Jadwiga / Waszkiewicz, Napoleon / Zwierz, Krzysztof

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: Dietary supplementation of gamma-linolenic acid (GLA) in the form of a commercial drug neoglandin (containing GLA and vitamin E), in people following alcohol abuse allows bypassing of the ineffective delta-6-desaturase system involved in the ... ...

    Abstract Dietary supplementation of gamma-linolenic acid (GLA) in the form of a commercial drug neoglandin (containing GLA and vitamin E), in people following alcohol abuse allows bypassing of the ineffective delta-6-desaturase system involved in the transformation of linoleic acid into GLA. Determination of the activity of N-acetyl-β-D-hexosaminidase (HEX) in the serum and urine reflects neoglandin action on the catabolism of glycoconjugates and the functioning of liver and kidneys in people following alcohol abuse.
    Material and methods: The serum and urine were collected from men with alcohol dependence, treated (
    Results: Our study on alcoholic men not treated with neoglandin indicates a significantly higher concentration of the serum and urinary HEX activity (nKat/L) on day 1 compared to days 7, 10, 14 and 30 (
    Conclusions: Neoglandin supplementation in alcoholic men significantly slows down the catabolism of glycoconjugates, thus reducing the effects of ethanol poisoning that are harmful to the kidneys. Neoglandin reduces the harmful effects of ethanol poisoning more on the kidneys than on the liver. The activity of HEX in the serum may be used in monitoring the treatment of alcoholism and whether alcohol reuse occurred during the therapy. In the early stages of alcohol withdrawal, urinary HEX activity can be used as a marker of the amount of alcohol consumed during previous alcohol abuse.
    MeSH term(s) Male ; Humans ; Young Adult ; Adult ; Middle Aged ; Alcoholism ; Hexosaminidases ; Substance Withdrawal Syndrome ; beta-N-Acetylhexosaminidases/urine ; Ethanol
    Chemical Substances Hexosaminidases (EC 3.2.1.-) ; beta-N-Acetylhexosaminidases (EC 3.2.1.52) ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20043413
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Circulating brain-derived neurotrophic factor, leptin, neuropeptide Y, and their clinical correlates in cystic fibrosis: a cross-sectional study.

    Nowak, Jan K / Szczepanik, Mariusz / Trypuć, Magdalena / Pogorzelski, Andrzej / Bobkowski, Waldemar / Grytczuk, Marcin / Minarowska, Alina / Wójciak, Rafał / Walkowiak, Jaroslaw

    Archives of medical science : AMS

    2018  Volume 16, Issue 5, Page(s) 1049–1056

    Abstract: Introduction: Cystic fibrosis (CF) involves chronic inflammation and decreased pulmonary function, which increase caloric demand. Yet, sufficient energy provision is hindered by reduced appetite and fat malabsorption. Brain-derived neurotrophic factor ( ... ...

    Abstract Introduction: Cystic fibrosis (CF) involves chronic inflammation and decreased pulmonary function, which increase caloric demand. Yet, sufficient energy provision is hindered by reduced appetite and fat malabsorption. Brain-derived neurotrophic factor (BDNF), leptin, and neuropeptide Y (NPY) belong to energy balance-regulating factors. We aimed to assess their concentrations in CF patients in order to search for potential clinical correlates.
    Material and methods: This was an exploratory, cross-sectional study. Patients' weight and height
    Results: The study enrolled 56 patients, of whom 29 (52%) were female and 17 (30%) were younger than 16 years. Median (1
    Conclusions: BDNF and leptin were not associated with weight
    Language English
    Publishing date 2018-04-23
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2203781-0
    ISSN 1734-1922
    ISSN 1734-1922
    DOI 10.5114/aoms.2018.75322
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Quantitative determination and localization of cathepsin D and its inhibitors.

    Minarowska, Alina / Karwowska, Alicja / Gacko, Marek

    Folia histochemica et cytobiologica

    2009  Volume 47, Issue 2, Page(s) 153–177

    Abstract: A literature survey was performed of the methods of quantitative assessment of the activity and concentration of cathepsin D and its inhibitors. Usefulness of non-modified and modified proteins and synthetic peptides as measurement substrates was ... ...

    Abstract A literature survey was performed of the methods of quantitative assessment of the activity and concentration of cathepsin D and its inhibitors. Usefulness of non-modified and modified proteins and synthetic peptides as measurement substrates was evaluated. The survey includes also chemical and immunochemical methods used to determine the distribution of cathepsin D and its inhibitors in cells and tissues.
    MeSH term(s) Amino Acid Sequence ; Animals ; Cathepsin D/analysis ; Cathepsin D/antagonists & inhibitors ; Enzyme Inhibitors/analysis ; Immunochemistry ; Molecular Sequence Data ; Spleen/enzymology ; Swine
    Chemical Substances Enzyme Inhibitors ; Cathepsin D (EC 3.4.23.5)
    Language English
    Publishing date 2009
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 605761-5
    ISSN 1897-5631 ; 0015-5586 ; 0239-8508
    ISSN (online) 1897-5631
    ISSN 0015-5586 ; 0239-8508
    DOI 10.2478/v10042-009-0073-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 6: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 545: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Human cathepsin D.

    Minarowska, Alina / Gacko, Marek / Karwowska, Alicja / Minarowski, Łukasz

    Folia histochemica et cytobiologica

    2008  Volume 46, Issue 1, Page(s) 23–38

    Abstract: A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this ... ...

    Abstract A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were considered.
    MeSH term(s) Amino Acid Sequence ; Cathepsin D/chemistry ; Cathepsin D/genetics ; Cathepsin D/isolation & purification ; Cathepsin D/metabolism ; Humans ; Molecular Sequence Data ; Protein Processing, Post-Translational ; Substrate Specificity
    Chemical Substances Cathepsin D (EC 3.4.23.5)
    Language English
    Publishing date 2008
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 605761-5
    ISSN 1897-5631 ; 0015-5586 ; 0239-8508
    ISSN (online) 1897-5631
    ISSN 0015-5586 ; 0239-8508
    DOI 10.2478/v10042-008-0003-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 6: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 545: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Objawy oczne w zwłóknieniu torbielowatym.

    Mrugacz, Małgorzata / Minarowska, Alina

    Klinika oczna

    2002  Volume 104, Issue 5-6, Page(s) 418–420

    Abstract: Cystic fibrosis is common genetic disease, inherited via an autosomal recessive pattern. The authors present state of knowledge, concerning genetic and diagnostic problems, clinical signs and treatment. Several clinically evident involvements of the eye ... ...

    Title translation Eye symptoms of cystic fibrosis.
    Abstract Cystic fibrosis is common genetic disease, inherited via an autosomal recessive pattern. The authors present state of knowledge, concerning genetic and diagnostic problems, clinical signs and treatment. Several clinically evident involvements of the eye such as xerophthalmia, deficiencies of tear film, functional changes of the optic nerve, papilloedema, nyctalopia, retinal hemorrhages, have been described.
    MeSH term(s) Cystic Fibrosis/complications ; Humans ; Night Blindness/etiology ; Optic Nerve Diseases/etiology ; Papilledema/etiology ; Xerophthalmia/etiology
    Language Polish
    Publishing date 2002
    Publishing country Poland
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 411755-4
    ISSN 0023-2157
    ISSN 0023-2157
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 339: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Regulatory role of cathepsin D in apoptosis.

    Minarowska, Alina / Minarowski, Lukasz / Karwowska, Alicja / Gacko, Marek

    Folia histochemica et cytobiologica

    2007  Volume 45, Issue 3, Page(s) 159–163

    Abstract: Cathepsin D (CTSD, EC 3.4.23.5) is well known aspartyl protease. Among different role in cell physiology, a new function of this enzyme is examined. Cathepsin D is an important regulator of apoptotic pathways in cells. It acts at different stage of ... ...

    Abstract Cathepsin D (CTSD, EC 3.4.23.5) is well known aspartyl protease. Among different role in cell physiology, a new function of this enzyme is examined. Cathepsin D is an important regulator of apoptotic pathways in cells. It acts at different stage of intrinsic and extrinsic pathway of apoptosis. Cathepsin D can either induce apoptosis in presence of cytotoxic factors, but in certain studies an inhibitory role in apoptosis was also reviewed. Detailed review of involvement of cathepsin D in cell apoptosis is a purpose of this paper.
    MeSH term(s) Animals ; Apoptosis/physiology ; Cathepsin D/physiology ; Humans
    Chemical Substances Cathepsin D (EC 3.4.23.5)
    Language English
    Publishing date 2007
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 605761-5
    ISSN 1897-5631 ; 0239-8508 ; 0015-5586
    ISSN (online) 1897-5631
    ISSN 0239-8508 ; 0015-5586
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 6: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 545: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Cathepsin D inhibitors.

    Gacko, Marek / Minarowska, Alina / Karwowska, Alicja / Minarowski, Łukasz

    Folia histochemica et cytobiologica

    2007  Volume 45, Issue 4, Page(s) 291–313

    Abstract: Inhibitors of cathepsin D belong to chemical compounds that estrify carboxyl groups of the Asp33 and Asp231 residues of its catalytic site, penta-peptides containing statin, i.e. the amino acid similar in structure to the tetraedric indirect product, and ...

    Abstract Inhibitors of cathepsin D belong to chemical compounds that estrify carboxyl groups of the Asp33 and Asp231 residues of its catalytic site, penta-peptides containing statin, i.e. the amino acid similar in structure to the tetraedric indirect product, and polypeptides found in the spare organs of many plants and forming permanent noncovalent complexes with cathepsin. Cathepsin D activity is also inhibited by alpha2-macroglobulin and antibodies directed against this enzyme. Methods used to determine the activity and concentration of these inhibitors and their analytical, preparative and therapeutic applications are discussed.
    MeSH term(s) Amino Acid Sequence ; Animals ; Bacteria/metabolism ; Cathepsin D/antagonists & inhibitors ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/classification ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/pharmacology ; Humans ; Kinetics ; Molecular Sequence Data ; Plants/metabolism ; Substrate Specificity
    Chemical Substances Enzyme Inhibitors ; Cathepsin D (EC 3.4.23.5)
    Language English
    Publishing date 2007
    Publishing country Poland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 605761-5
    ISSN 1897-5631 ; 0015-5586 ; 0239-8508
    ISSN (online) 1897-5631
    ISSN 0015-5586 ; 0239-8508
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 6: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 545: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Role of cathepsin A and cathepsin C in the regulation of glycosidase activity.

    Minarowska, Alina / Minarowski, Łukasz / Karwowska, Alicja / Milewska, Anna Justyna / Gacko, Marek

    Folia histochemica et cytobiologica

    2012  Volume 50, Issue 1, Page(s) 20–24

    Abstract: Increased tissue activity of cathepsin A and cathepsin C can be observed in many pathological conditions. It is associated with an enhanced degradation of glycosaminoglycans, proteoglycans, and glycoproteins, and results in their decreased tissue content. ...

    Abstract Increased tissue activity of cathepsin A and cathepsin C can be observed in many pathological conditions. It is associated with an enhanced degradation of glycosaminoglycans, proteoglycans, and glycoproteins, and results in their decreased tissue content. Cathepsin C releases the glycosidases from complexes formed with cathepsin A, and reinstates their activity. In this review a current state of knowledge is presented concerning the regulation of selected glycosidases activity by cathepsin A (EC 3.4.16.1) and C (EC 3.4.14.1).
    MeSH term(s) Amino Acid Sequence ; Cathepsin A/metabolism ; Cathepsin C/metabolism ; Glycoside Hydrolases/metabolism ; Humans ; Models, Molecular ; Molecular Sequence Data
    Chemical Substances Glycoside Hydrolases (EC 3.2.1.-) ; Cathepsin C (EC 3.4.14.1) ; Cathepsin A (EC 3.4.16.5)
    Language English
    Publishing date 2012-04-24
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 605761-5
    ISSN 1897-5631 ; 0015-5586 ; 0239-8508
    ISSN (online) 1897-5631
    ISSN 0015-5586 ; 0239-8508
    DOI 10.2478/18692
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 6: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 545: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top