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  1. Article ; Online: Menopause hormone therapy and physical performance: The Canadian Longitudinal Study on Aging.

    Macêdo, Pedro R S / Macêdo, Sabrina G G F / Velez, Maria P / Câmara, Saionara M A

    Maturitas

    2024  Volume 184, Page(s) 107959

    Abstract: Objective: To examine the association between menopause hormone therapy (MHT) and physical performance among women from the Canadian Longitudinal Study on Aging.: Study design: Cross-sectional study of 12,506 postmenopausal Canadian women.: Main ... ...

    Abstract Objective: To examine the association between menopause hormone therapy (MHT) and physical performance among women from the Canadian Longitudinal Study on Aging.
    Study design: Cross-sectional study of 12,506 postmenopausal Canadian women.
    Main outcome measures: Grip strength (kg), gait speed (m/s), timed up and go (s), chair rise (s), and balance (s) were assessed following standard procedures. The association between MHT and physical performance was evaluated using linear regression models adjusted for age, education, study site, smoking, alcohol consumption, body mass index, diabetes, hypertension, and hysterectomy. Sensitivity analyses were conducted according to age at study visit (<65 vs. ≥65 years), body mass index (<25 kg/m
    Results: Compared with those who never used MHT, prior or current use was associated with better performance on the timed up and go test (β: -0.19; 95%CI: -0.28; -0.11) and faster gait speed (β = 0.01, 95%CI = 0.00; 0.02). No association was found for grip strength, balance, and chair rise. Results did not change by body mass index, physical activity, or duration of MHT use. When stratified by age at study visit, the effect remained significant only in among those aged 65 years or more. Starting MHT <5 years after menopause was associated with better physical performance.
    Conclusions: MHT was associated with better physical performance in gait speed and timed up and go tests. The cross-sectional design of the study limits causal interpretation. Prospective studies are needed to confirm our results.
    Language English
    Publishing date 2024-03-01
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 80460-5
    ISSN 1873-4111 ; 0378-5122
    ISSN (online) 1873-4111
    ISSN 0378-5122
    DOI 10.1016/j.maturitas.2024.107959
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  2. Article ; Online: Re: Working classification and the quest for an effective, reconstructive management strategy in Y duplication of male urethra.

    Macedo, Antonio

    Journal of pediatric urology

    2021  Volume 17, Issue 3, Page(s) 415–416

    Language English
    Publishing date 2021-03-05
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2021.02.029
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  3. Article ; Online: Editorial Comment: Effects of spongioplasty on neourethral function following hypospadias repair: an experimental study on rabbits.

    Macedo, Antonio

    International braz j urol : official journal of the Brazilian Society of Urology

    2020  Volume 46, Issue 3, Page(s) 444–445

    MeSH term(s) Animals ; Humans ; Hypospadias ; Male ; Rabbits ; Surgical Flaps ; Urethra
    Language English
    Publishing date 2020-05-14
    Publishing country Brazil
    Document type Editorial ; Comment
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2019.0453.1
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  4. Book ; Online: Acceso abierto como bien común y público en Angola

    Becerril-García, Arianna / Aguado-López, Eduardo / Macedo-García, Alejandro / Neupane, Bhanu / Gungula, Eurico Wongo

    colaboración Sur-Sur

    2022  

    Keywords Media studies ; open access, scientific communication, international cooperation, media
    Language Spanish
    Size 1 electronic resource (474 pages)
    Publisher Ariadna Ediciones
    Publishing place Santiago, Chile
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030378614
    ISBN 9789893339510 ; 9893339510
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay.

    Macedo-Viñas, Marina / Lucas, Andrea

    Biomedicines

    2023  Volume 11, Issue 11

    Abstract: 1) Background: Infections are a main cause of morbidity and mortality among burn patients. The spectrum of microorganisms depends on the epidemiological context and treatment practices. We aimed to describe the evolution of microbial flora colonizing ... ...

    Abstract (1) Background: Infections are a main cause of morbidity and mortality among burn patients. The spectrum of microorganisms depends on the epidemiological context and treatment practices. We aimed to describe the evolution of microbial flora colonizing burn wounds among patients hospitalized during 15 or more days at the National Burn Center in 2015. (2) Methods: Demographic data, length of stay, total body surface area burn, and status at discharge were collected from electronic records and culture results from the laboratory database. (3) Results: Among 98 included patients, 87 were colonized. The mean length of stay was 39 days overall and 16 days in the ICU.
    Language English
    Publishing date 2023-10-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11112900
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  6. Article ; Online: Random-hopping approach to fluctuation phenomena in quantum dots with chiral symmetry.

    Pessoa, N L / Barbosa, A L R / Macêdo, A M S

    Chaos (Woodbury, N.Y.)

    2023  Volume 33, Issue 11

    Abstract: We propose a numerical approach to study mesoscopic fluctuations in quantum dots with chiral symmetry. Our method involves applying the random-hopping model to a tight-binding Hamiltonian, allowing us to calculate the conductance and shot-noise power ... ...

    Abstract We propose a numerical approach to study mesoscopic fluctuations in quantum dots with chiral symmetry. Our method involves applying the random-hopping model to a tight-binding Hamiltonian, allowing us to calculate the conductance and shot-noise power distributions for systems belonging to the three chiral symmetry classes of random matrix theory. Furthermore, we demonstrate that the spectral fluctuations of quantum dots belonging to the Wigner-Dyson symmetry classes of random matrix theory can be obtained by applying the random-hopping model to a scattering region that was originally integrable, thus bypassing the need to use the boundaries of chaotic billiards.
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1472677-4
    ISSN 1089-7682 ; 1054-1500
    ISSN (online) 1089-7682
    ISSN 1054-1500
    DOI 10.1063/5.0168974
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  7. Article ; Online: Ibuprofen-Immobilized Thin Films: A Novel Approach to Improve the Clearance of Protein-Bound Uremic Toxins.

    Rodrigues, Flávia S C / Brilhante, Dialina / Macêdo, Ana / Pires, Rita F / Faria, Mónica

    ACS applied materials & interfaces

    2024  Volume 16, Issue 5, Page(s) 6589–6604

    Abstract: Chronic kidney disease (CKD), a pressing global health issue, affects millions and leads to end-stage renal disease (ESRD). Hemodialysis (HD) is a crucial treatment for ESRD, yet its limited efficiency in removing protein-bound uremic toxins (PBUTs) ... ...

    Abstract Chronic kidney disease (CKD), a pressing global health issue, affects millions and leads to end-stage renal disease (ESRD). Hemodialysis (HD) is a crucial treatment for ESRD, yet its limited efficiency in removing protein-bound uremic toxins (PBUTs) results in high morbidity and mortality rates. A high affinity of pharmaceutical drugs for human serum albumin (HSA) can be leveraged to compete effectively with PBUTs for the same HSA binding sites, thereby enabling them to be capable of displacing these toxins. One such drug is ibuprofen (IBF), known for its very high affinity for HSA and sharing the same binding site as indoxyl sulfate (IS). This study explores the development of IBF-immobilized cellulose acetate-based (CA-based) thin films. The films were created by reacting CA with IBF-modified silica precursors at varying concentrations. The presence of IBF in CA/TEOS/APTES-IBF-3 and CA/TEOS-IBF-25 films, containing 3 and 25 wt % IBF, respectively, was confirmed through
    MeSH term(s) Humans ; Uremic Toxins ; Ibuprofen ; Uremia ; Quality of Life ; Protein Binding ; Kidney Failure, Chronic/therapy ; Renal Dialysis ; Serum Albumin, Human/metabolism ; Toxins, Biological ; Indican
    Chemical Substances Uremic Toxins ; Ibuprofen (WK2XYI10QM) ; Serum Albumin, Human (ZIF514RVZR) ; Toxins, Biological ; Indican (N187WK1Y1J)
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c15291
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  8. Article ; Online: Systematic review and meta-analysis: assessing the accuracy of rapid immunochromatographic tests in dengue diagnosis.

    Macêdo, Jéssica V L / Júnior, Alberto G S / Oliveira, Maria D L / Andrade, César A S

    Diagnostic microbiology and infectious disease

    2024  Volume 109, Issue 2, Page(s) 116227

    Abstract: The objective of this systematic review is to analyze the diagnostic accuracy of rapid dengue diagnostic tests. The search was conducted in the following databases: LILACS, Medline (Pubmed), CRD, The Cochrane Library, Trip Medical Database and Google ... ...

    Abstract The objective of this systematic review is to analyze the diagnostic accuracy of rapid dengue diagnostic tests. The search was conducted in the following databases: LILACS, Medline (Pubmed), CRD, The Cochrane Library, Trip Medical Database and Google Scholar. ELISA and PCR assays were adopted as reference methods. Thirty-four articles were included in this systematic review. Receiver operating characteristic (ROC) and Forest Plot were performed to evaluate sensitivity and specificity for each parameter analyzed (NS1, IgM and IgG). The results revealed that the combined analysis of the IgM antibody with the NS1 antigen resulted in greater sensitivity than the isolated analysis of IgM. The three analytes together showed the best performance, with a combined sensitivity of 90 % (95 % CI: 89-92 %) using ELISA as a comparator. Thus, the present review provides relevant knowledge for decision-making between the available rapid diagnostic tests.
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2024.116227
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  9. Article ; Online: Effectiveness of undergraduate medical students training on LGBTQIA + people health: a systematic review and meta-analysis.

    Macedo, Ana / Aurindo, Maria / Febra, Cláudia

    BMC medical education

    2024  Volume 24, Issue 1, Page(s) 63

    Abstract: Background: Adequacy of learning models and their ability to engage students and match session's objectives are critical factors in achieving the desired outcome. In this systematic review and meta-analysis, we assess the methodological approach, ... ...

    Abstract Background: Adequacy of learning models and their ability to engage students and match session's objectives are critical factors in achieving the desired outcome. In this systematic review and meta-analysis, we assess the methodological approach, content, and effectiveness of training initiatives addressing medical students' knowledge, attitudes, confidence and discrimination perception towards LGBTQIA + people.
    Method: PubMed, Web of Science, Medline and Scopus were searched to identify published studies, from 2013 to 2023, on effectiveness of training initiatives addressing medical students' knowledge, attitudes, confidence and discrimination perception towards LGBTQIA + people. The risk of bias of the selected studies was assessed by the Medical Education Research Study Quality Instrument. Overall effect sizes were calculated using a Mantel-Haenszel method, fixed effect meta-analyses.
    Results: A total of 22 studies were included, representing 2,164 medical students. The interventions were highly diverse and included seminars, lectures, videos, real-case discussions, roleplay, and group discussions with people from the LGBTQIA + community. After the interventions, there was a significant improvement in self-confidence and comfort interacting with patients and in the understanding of the unique and specific health concerns experienced by LGBTQIA + patients.
    Conclusion: Our findings indicated that the outcomes of interventions training actions for medical students that promote knowledge and equity regarding LGBTQIA + people, regardless of their scope, methodology and duration, result in a considerable increase in students' self-confidence and comfort interacting with LGBTQIA + patients, highlight the need for more actions and programs in this area promoting a more inclusive society and greater equity.
    MeSH term(s) Humans ; Students, Medical ; Sexual and Gender Minorities ; Learning ; Attitude ; Education, Medical
    Language English
    Publishing date 2024-01-16
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-024-05041-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Two-dimensional dilute Baxter-Wu model: Transition order and universality.

    Macêdo, A R S / Vasilopoulos, A / Akritidis, M / Plascak, J A / Fytas, N G / Weigel, M

    Physical review. E

    2023  Volume 108, Issue 2-1, Page(s) 24140

    Abstract: We investigate the critical behavior of the two-dimensional spin-1 Baxter-Wu model in the presence of a crystal-field coupling Δ with the goal of determining the universality class of transitions along the second-order part of the transition line as one ... ...

    Abstract We investigate the critical behavior of the two-dimensional spin-1 Baxter-Wu model in the presence of a crystal-field coupling Δ with the goal of determining the universality class of transitions along the second-order part of the transition line as one approaches the putative location of the multicritical point. We employ extensive Monte Carlo simulations using two different methodologies: (i) a study of the zeros of the energy probability distribution, closely related to the Fisher zeros of the partition function, and (ii) the well-established multicanonical approach employed to study the probability distribution of the crystal-field energy. A detailed finite-size scaling analysis in the regime of second-order phase transitions in the (Δ,T) phase diagram supports previous claims that the transition belongs to the universality class of the four-state Potts model. For positive values of Δ, we observe the presence of strong finite-size effects, indicative of crossover effects due to the proximity of the first-order part of the transition line. Finally, we demonstrate how a combination of cluster and heat-bath updates allows one to equilibrate larger systems, and we demonstrate the potential of this approach for resolving the ambiguities observed in the regime of Δ≳0.
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.108.024140
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