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  1. Article ; Online: Impact of social media and applications on everyday cardiovascular practice.

    Lombardi, Marco / Infusino, Fabio / Cimino, Sara

    Minerva cardioangiologica

    2020  Volume 68, Issue 4, Page(s) 288–290

    MeSH term(s) Cardiology ; Humans ; Social Media
    Language English
    Publishing date 2020-04-21
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123583-7
    ISSN 1827-1618 ; 0026-4725
    ISSN (online) 1827-1618
    ISSN 0026-4725
    DOI 10.23736/S0026-4725.20.05266-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 14: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The role of cardiologists in the coronavirus disease 2019 pandemic.

    Fedele, Francesco / Infusino, Fabio / Severino, Paolo / Mancone, Massimo

    Kardiologia polska

    2020  Volume 78, Issue 7-8, Page(s) 808–809

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiologists ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-25
    Publishing country Poland
    Document type Journal Article ; Comment
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.15572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Transcervical approach for TAVI: Perhaps more than a fallback.

    Mancone, Massimo / Infusino, Fabio / Fedele, Francesco / Sardella, Gennaro

    International journal of cardiology

    2020  Volume 327, Page(s) 66–67

    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Fluoroscopy ; Humans ; Transcatheter Aortic Valve Replacement/adverse effects
    Language English
    Publishing date 2020-12-31
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2020.12.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1673: Show issues Location:
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  4. Article ; Online: Unrecognized Hole in the Aortic Stenosis Heart: Acquired Gerbode Defect Detected During Pretransfemoral Aortic Valve Implantation Evaluation.

    Nesta, Marialisa / Bruno, Piergiorgio / d'Acierno, Edoardo Maria / Cutrone, Gessica / Rovere, Giuseppe / Burzotta, Francesco / Trani, Carlo / Romagnoli, Enrico / Aurigemma, Cristina / Infusino, Fabio / Locorotondo, Gabriella / Chiariello, Giovanni A / Cammertoni, Federico / Grandinetti, Maria / Pavone, Natalia / Massetti, Massimo

    Circulation. Cardiovascular imaging

    2024  , Page(s) e016151

    Language English
    Publishing date 2024-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.123.016151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Relationship between angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and SARS-CoV-2 infection: where are we?

    Infusino, Fabio / Cimino, Sara / Lombardi, Marco / Mancone, Massimo / Cavarretta, Elena / Frati, Giacomo / Pugliese, Francesco / Fedele, Francesco / Biondi Zoccai, Giuseppe

    Minerva cardioangiologica

    2020  Volume 68, Issue 4, Page(s) 339–346

    Abstract: In recent months SARS-CoV-2 has spread rapidly throughout the world. The case fatality rate is higher in cardiovascular disease and hypertension. Other comorbidities do not seem to confer the same risk, therefore the understanding of the relationship ... ...

    Abstract In recent months SARS-CoV-2 has spread rapidly throughout the world. The case fatality rate is higher in cardiovascular disease and hypertension. Other comorbidities do not seem to confer the same risk, therefore the understanding of the relationship between infection and cardiovascular system could be a crucial point for the fight against the virus. A great interest is directed towards the angiotensin 2 converting enzyme (ACE 2) which is the SARS-CoV-2 receptor and creates important connections between the virus replication pathway, the cardiovascular system and blood pressure. All cardiovascular conditions share an imbalance of the renin angiotensin system in which ACE 2 plays a central role. In the early pandemic period, much confusion has appeared about the management of therapy with angiotensin converting enzyme inhibitors and angiotensin receptor blockers especially in infected patients and in those at risk of critical illness in case of infection. In this article we will try to reorder the major opinions currently emerging on this topic.
    MeSH term(s) Angiotensin II Type 1 Receptor Blockers/therapeutic use ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Animals ; Antihypertensive Agents/therapeutic use ; COVID-19 ; Coronavirus Infections/drug therapy ; Coronavirus Infections/physiopathology ; Humans ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/physiopathology ; Renin-Angiotensin System
    Chemical Substances Angiotensin II Type 1 Receptor Blockers ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Antihypertensive Agents
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 123583-7
    ISSN 1827-1618 ; 0026-4725
    ISSN (online) 1827-1618
    ISSN 0026-4725
    DOI 10.23736/S0026-4725.20.05271-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Susceptibility to ischaemic heart disease: Focusing on genetic variants for ATP-sensitive potassium channel beyond traditional risk factors.

    Severino, Paolo / D'Amato, Andrea / Netti, Lucrezia / Pucci, Mariateresa / Mariani, Marco V / Cimino, Sara / Birtolo, Lucia I / Infusino, Fabio / De Orchi, Paolo / Palmirotta, Raffaele / Lovero, Domenica / Silvestris, Franco / Caputo, Viviana / Pizzuti, Antonio / Miraldi, Fabio / Maestrini, Viviana / Mancone, Massimo / Fedele, Francesco

    European journal of preventive cardiology

    2021  Volume 28, Issue 13, Page(s) 1495–1500

    Abstract: Aims: Ischaemic heart disease is classically associated with coronary artery disease. Recent evidences showed the correlation between coronary microvascular dysfunction and ischaemic heart disease, even independently of coronary artery disease. Ion ... ...

    Abstract Aims: Ischaemic heart disease is classically associated with coronary artery disease. Recent evidences showed the correlation between coronary microvascular dysfunction and ischaemic heart disease, even independently of coronary artery disease. Ion channels represent the final effectors of blood flow regulation mechanisms and their genetic variants, in particular of Kir6.2 subunit of the ATP-sensitive potassium channel (KATP), are reported to be involved in ischaemic heart disease susceptibility. The aim of the present study is to evaluate the role of KATP channel and its genetic variants in patients with ischaemic heart disease and evaluate whether differences exist between coronary artery disease and coronary microvascular dysfunction.
    Methods: A total of 603 consecutive patients with indication for coronary angiography due to suspected myocardial ischaemia were enrolled. Patients were divided into three groups: coronary artery disease (G1), coronary microvascular dysfunction (G2) and normal coronary arteries (G3). Analysis of four single nucleotide polymorphisms (rs5215, rs5216, rs5218 and rs5219) of the KCNJ11 gene encoding for Kir6.2 subunit of the KATP channel was performed.
    Results: rs5215 A/A and G/A were significantly more represented in G1, while rs5215 G/G was significantly more represented in G3, rs5216 G/G and C/C were both more represented in G3, rs5218 C/C was more represented in G1 and rs5219 G/A was more represented in G1, while rs5219 G/G was significantly more represented in G2. At multivariate analysis, single nucleotide polymorphism rs5215_G/G seems to represent an ischaemic heart disease independent protective factor.
    Conclusions: These results suggest the potential role of KATP genetic variants in ischaemic heart disease susceptibility, as an independent protective factor. They may lead to a future perspective for gene therapy against ischaemic heart disease.
    Language English
    Publishing date 2021-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1177/2047487320926780
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4686: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article: Effects of Ivabradine on Residual Myocardial Ischemia after PCI Evaluated by Stress Echocardiography.

    Calcagno, Simone / Infusino, Fabio / Dettori, Olga / Taccheri, Temistocle / Bruno, Pasqualina / Maestrini, Viviana / Sardella, Gennaro / Mancone, Massimo / Fedele, Francesco

    Cardiology research and practice

    2019  Volume 2019, Page(s) 9185876

    Abstract: Background: Residual angina after PCI is a frequently occurring disease. Ivabradine improves symptoms but its role in patients without left ventricular systolic dysfunction is still unclear. The aim was to quantify the effects of ivabradine in terms of ... ...

    Abstract Background: Residual angina after PCI is a frequently occurring disease. Ivabradine improves symptoms but its role in patients without left ventricular systolic dysfunction is still unclear. The aim was to quantify the effects of ivabradine in terms of MVO
    Methods: Twenty-eight consecutive patients with residual angina after PCI were randomized to ivabradine 5 mg twice/day (IG) or standard therapy (CG). All patients performed a stress echocardiography at the enrollment and after 30 days. MVO
    Results: The exercise time was longer in IG 9'49″ ± 48″ vs 8'09″ ± 59″ in CG (
    Conclusions: Ivabradine seems to produce a significant improvement of ischemic threshold, chronotropic reserve, and diastolic function.
    Language English
    Publishing date 2019-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2506187-2
    ISSN 2090-0597 ; 2090-8016
    ISSN (online) 2090-0597
    ISSN 2090-8016
    DOI 10.1155/2019/9185876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Myocardial Ischemia and Diabetes Mellitus: Role of Oxidative Stress in the Connection between Cardiac Metabolism and Coronary Blood Flow.

    Severino, Paolo / D'Amato, Andrea / Netti, Lucrezia / Pucci, Mariateresa / Infusino, Fabio / Maestrini, Viviana / Mancone, Massimo / Fedele, Francesco

    Journal of diabetes research

    2019  Volume 2019, Page(s) 9489826

    Abstract: Ischemic heart disease (IHD) has several risk factors, among which diabetes mellitus represents one of the most important. In diabetic patients, the pathophysiology of myocardial ischemia remains unclear yet: some have atherosclerotic plaque which ... ...

    Abstract Ischemic heart disease (IHD) has several risk factors, among which diabetes mellitus represents one of the most important. In diabetic patients, the pathophysiology of myocardial ischemia remains unclear yet: some have atherosclerotic plaque which obstructs coronary blood flow, others show myocardial ischemia due to coronary microvascular dysfunction in the absence of plaques in epicardial vessels. In the cross-talk between myocardial metabolism and coronary blood flow (CBF), ion channels have a main role, and, in diabetic patients, they are involved in the pathophysiology of IHD. The exposition to the different cardiovascular risk factors and the ischemic condition determine an imbalance of the redox state, defined as oxidative stress, which shows itself with oxidant accumulation and antioxidant deficiency. In particular, several products of myocardial metabolism, belonging to oxidative stress, may influence ion channel function, altering their capacity to modulate CBF, in response to myocardial metabolism, and predisposing to myocardial ischemia. For this reason, considering the role of oxidative and ion channels in the pathophysiology of myocardial ischemia, it is allowed to consider new therapeutic perspectives in the treatment of IHD.
    MeSH term(s) Antioxidants/metabolism ; Coronary Circulation ; Diabetes Complications/metabolism ; Diabetes Mellitus/metabolism ; Diabetes Mellitus/pathology ; Heart/physiology ; Heart/physiopathology ; Humans ; Ion Channels/metabolism ; Ions/metabolism ; MicroRNAs/metabolism ; Myocardial Ischemia/complications ; Myocardial Ischemia/metabolism ; Oxidation-Reduction ; Oxidative Stress ; Peroxynitrous Acid/metabolism ; Risk Factors
    Chemical Substances Antioxidants ; Ion Channels ; Ions ; MicroRNAs ; Peroxynitrous Acid (14691-52-2)
    Language English
    Publishing date 2019-04-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2711897-6
    ISSN 2314-6753 ; 2314-6745
    ISSN (online) 2314-6753
    ISSN 2314-6745
    DOI 10.1155/2019/9489826
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Successful Transcatheter Treatment of Left Pulmonary Artery to Left Atrium Communication Diagnosed in Adulthood.

    Lillo, Rosa / Graziani, Francesca / Burzotta, Francesco / Locorotondo, Gabriella / Aurigemma, Cristina / Romagnoli, Enrico / Bibiana Delogu, Angelica / Grandinetti, Maria / Panaioli, Elena / Scacciavillani, Roberto / Infusino, Fabio / Savino, Giancarlo / Massetti, Massimo / Trani, Carlo

    Circulation. Cardiovascular imaging

    2020  Volume 13, Issue 11, Page(s) e010668

    MeSH term(s) Adult ; Cardiac Catheterization/instrumentation ; Female ; Heart Atria/abnormalities ; Heart Atria/diagnostic imaging ; Heart Atria/physiopathology ; Heart Defects, Congenital/diagnostic imaging ; Heart Defects, Congenital/physiopathology ; Heart Defects, Congenital/therapy ; Humans ; Pulmonary Artery/abnormalities ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/physiopathology ; Recovery of Function ; Septal Occluder Device ; Treatment Outcome
    Language English
    Publishing date 2020-11-06
    Publishing country United States
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.120.010668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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