Article ; Online: Relationship between macular intervortex vein anastomosis and optical coherence tomography biomarkers in chronic central serous chorioretinopathy.
Photodiagnosis and photodynamic therapy
2023 Volume 42, Page(s) 103559
Abstract: Backgrounds: To evaluate the optical coherence tomography (OCT) biomarkers of patients with central serous chorioretinopathy (CSC) according to the presence or absence of direct anatomical relation to intervortex vein anastomosis (IVA) on indocyanine ... ...
| Abstract | Backgrounds: To evaluate the optical coherence tomography (OCT) biomarkers of patients with central serous chorioretinopathy (CSC) according to the presence or absence of direct anatomical relation to intervortex vein anastomosis (IVA) on indocyanine green angiography. Methods: We reviewed the records of 39 patients with chronic CSC. Patients were categorized in 2 groups: presence of IVA(Group A) or absence of IVA(Group B) in the macular region. Localization of IVA was categorized in 3 areas according to ETDRS grid:inner 1 mm circle (area-1), 1-3 mm middle circle (area-2) and 3-6 mm outer circle (area-3). Results: There were 31 eyes in Group A,21 eyes in Group B. Mean age of the patients was 52.5 ± 11.3years in Group A,47.2 ± 11years in Group B(p<0.001).Mean initial visual acuity (VA) was 0.38±0.38LogMAR in Group A, 0.19±0.21LogMAR in Group B(p<0.001).Mean subfoveal choroidal thickness(SFCT) was 436.3 ± 134.3µ in Group A,480.2 ± 136.6µ in Group B(p<0.001).Localization of IVA in area-1 was correlated with inner choroidal attenuation (ICA) and leakage on IVA(p = 0.011,p = 0.02). Localization of IVA in area-3 was correlated with irregular lesions on RPE(p = 0.042).Smokestack configuration,intraretinal cysts and ICA were correlated with worse initial VA(p<0.001,p = 0.001 and p = 0.04).Shaggy subtype of photoreceptor disruption was associated with better initial VA(p = 0.003). Conclusions: We detected older age, worse initial VA and thinner SFCT in patients with chronic CSC and macular region IVA(m-IVA). Long term follow-up of patients with and without m-IVA may exhibit the difference in treatment outcomes and development of neovasculopathy. |
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| MeSH term(s) | Arteriovenous Anastomosis/diagnostic imaging ; Arteriovenous Anastomosis/pathology ; Central Serous Chorioretinopathy/diagnostic imaging ; Central Serous Chorioretinopathy/pathology ; Retina/diagnostic imaging ; Retina/pathology ; Tomography, Optical Coherence ; Biomarkers ; Humans ; Male ; Female ; Adult ; Middle Aged ; Retrospective Studies ; Age Factors ; Visual Acuity |
| Chemical Substances | Biomarkers |
| Language | English |
| Publishing date | 2023-04-06 |
| Publishing country | Netherlands |
| Document type | Journal Article |
| ZDB-ID | 2149918-4 |
| ISSN | 1873-1597 ; 1572-1000 |
| ISSN (online) | 1873-1597 |
| ISSN | 1572-1000 |
| DOI | 10.1016/j.pdpdt.2023.103559 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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