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  1. Article ; Online: Layered Chalcogenide Scintillators Enabled by Reversible Hydrous-Induced Phase Transformation for High-Resolution X-ray Imaging.

    Yang, Jinhai / Huang, Xixi / Xu, Xieming / Lu, Hao / Wang, Shuaihua / Wu, Shaofan

    ACS applied materials & interfaces

    2024  Volume 16, Issue 12, Page(s) 15050–15058

    Abstract: Scintillation materials have been widely used in various fields, such as medical diagnosis and industrial detection. Chalcogenides have the potential to become a new generation of high-performance scintillation materials due to their high effective ... ...

    Abstract Scintillation materials have been widely used in various fields, such as medical diagnosis and industrial detection. Chalcogenides have the potential to become a new generation of high-performance scintillation materials due to their high effective atomic number and good resistance to radiation damage. However, research on their application in radiation detection is currently very scarce. Herein, single crystals of rare earth ion-doped ternary chalcogenides NaGaS
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c19558
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evolution of the Microstructure, Hybridization, and Internal Stress of Al-Doped Diamond-Like Carbon Coatings: A Molecular Dynamics Simulation.

    Huang, Jinhai / Peng, Jihua / Qiu, Xianting / Li, Xiaoling

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 11, Page(s) 3895–3904

    Abstract: This work modified some parameters related to the bond order in REBO-II of the C-C interaction and simulated the ta-C:Al film deposition using the large-scale atomic/molecular massively parallel simulator especially focused on the effect of the Al-doping ...

    Abstract This work modified some parameters related to the bond order in REBO-II of the C-C interaction and simulated the ta-C:Al film deposition using the large-scale atomic/molecular massively parallel simulator especially focused on the effect of the Al-doping content on the microstructural and mechanical properties of tetrahedral amorphous carbon films. According to the Al existence state, the Al content in the films can be divided into three ranges: range I─under 5 at % Al, a single Al atom or a small cluster with 2-3 Al atoms disperses separately in the matrix; range II─at 5-20 at. % Al, the number and incorporating Al atoms of the clusters increase with the Al content; range III─above 20 at. % Al, only a solid network of aluminum atoms forms, which becomes thickened and densified with Al content increment. The existence states of Al atoms play an essential role in determining mechanical and structural properties. With Al content increasing in the films, the isolated small cluster of atoms evolved into a whole network of aluminum inter-crossing with the C-network. With the evolution of Al existence states, the sp
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c03200
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  3. Article ; Online: TMR-Array-Based Pipeline Location Method and Its Realization

    Zhenning Wu / Hanyang Huang / Guangdong Zhao / Jinhai Liu

    Sustainability, Vol 15, Iss 9816, p

    2023  Volume 9816

    Abstract: Pipeline inspection is important to ensure the safe operation of pipelines. Obtaining the location of an underground pipeline is a prerequisite for most inspection technologies. Existing pipeline location methods can find a pipeline’s location, but they ... ...

    Abstract Pipeline inspection is important to ensure the safe operation of pipelines. Obtaining the location of an underground pipeline is a prerequisite for most inspection technologies. Existing pipeline location methods can find a pipeline’s location, but they require multiple measurements and cannot be used by automatic inspection robots. In this paper, a tunnel magnetoresistance (TMR)-sensor-array-based pipeline location method is proposed to solve this problem. Firstly, a detection probe is designed using a TMR sensor array. It is calibrated by the improved ellipsoid fitting method to measure the magnetic field around the pipeline accurately. Secondly, a relative pipeline-position-locating method is proposed by detecting the phases of the magnetic induction signals at different frequencies. Thirdly, a three-dimensional pipeline location method is proposed. The horizontal and vertical distances and the angle between the pipeline and the probe are calculated by measuring the magnetic induction amplitude. Finally, a simulation model and a test platform are established, and the experimental results illustrate that, by adopting the TMR array, the three-dimensional pipeline location method can locate a pipeline in real time in three dimensions with good accuracy.
    Keywords pipeline current mapper ; nondestructive testing ; tunnel magnetoresistance ; ellipsoid fitting ; infrastructure ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 669
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Combining small airway parameters with conventional parameters obtained during spirometry to diagnose airflow obstruction: A cross-sectional study.

    Wang, Zhufeng / Lin, Junfeng / Liang, Lina / Li, Yun / Huang, Jinhai / Gao, Yi / Zheng, Jinping

    Respirology (Carlton, Vic.)

    2024  

    Abstract: Background and objective: The use of small airway parameters generated by spirometry, namely forced expiratory flow between 25% and 75% of forced vital capacity (FVC) (FEF: Methods: We conducted a cross-sectional observational study in which ... ...

    Abstract Background and objective: The use of small airway parameters generated by spirometry, namely forced expiratory flow between 25% and 75% of forced vital capacity (FVC) (FEF
    Methods: We conducted a cross-sectional observational study in which spirometry and bronchodilator responsiveness (BDR) data were collected in a healthcare centre from May 2021 to August 2022 and in a tertiary hospital from January 2017 to March 2022. Discordance was assessed between the classification of test results by the large airway parameters of forced expiratory volume in 1 second (FEV
    Results: Our study included 26,658 people. Among people with a normal FVC (n = 14,688), 3.7%, 4.5% and 3.6% of cases exhibited normal FEV
    Conclusion: It is important to consider both large and small airway parameters in spirometry to avoid missing a diagnosis of airflow obstruction.
    Language English
    Publishing date 2024-04-24
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14725
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    In stock of ZB MED Cologne/Königswinter

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  5. Article: Advances in Non-Invasive Neuromodulation Techniques for Improving Cognitive Function: A Review.

    Chen, Ruijuan / Huang, Lengjie / Wang, Rui / Fei, Jieying / Wang, Huiquan / Wang, Jinhai

    Brain sciences

    2024  Volume 14, Issue 4

    Abstract: Non-invasive neuromodulation techniques are widely utilized to study and improve cognitive function, with the aim of modulating different cognitive processes. For workers performing high-intensity mental and physical tasks, extreme fatigue may not only ... ...

    Abstract Non-invasive neuromodulation techniques are widely utilized to study and improve cognitive function, with the aim of modulating different cognitive processes. For workers performing high-intensity mental and physical tasks, extreme fatigue may not only affect their working efficiency but may also lead to cognitive decline or cognitive impairment, which, in turn, poses a serious threat to their physical health. The use of non-invasive neuromodulation techniques has important research value for improving and enhancing cognitive function. In this paper, we review the research status, existing problems, and future prospects of transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), transcranial magnetic stimulation (TMS), and transcutaneous acupoint stimulation (TAS), which are the most studied physical methods in non-invasive neuromodulation techniques to improve and enhance cognition. The findings presented in this paper will be of great reference value for the in-depth study of non-invasive neuromodulation techniques in the field of cognition.
    Language English
    Publishing date 2024-04-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci14040354
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  6. Article: An in vitro investigation into the impact of corneal rinsing on riboflavin/UVA corneal cross-linking.

    Morgan, Siân R / O'Brart, David P S / Huang, Jinhai / Meek, Keith M / Hayes, Sally

    Eye and vision (London, England)

    2024  Volume 11, Issue 1, Page(s) 8

    Abstract: Background: Corneal cross-linking (CXL) using riboflavin and ultraviolet-A light (UVA) is a treatment used to prevent progression of keratoconus. This ex vivo study assesses the impact on CXL effectiveness, as measured by tissue enzymatic resistance and ...

    Abstract Background: Corneal cross-linking (CXL) using riboflavin and ultraviolet-A light (UVA) is a treatment used to prevent progression of keratoconus. This ex vivo study assesses the impact on CXL effectiveness, as measured by tissue enzymatic resistance and confocal microscopy, of including a pre-UVA corneal surface rinse with balanced salt solution (BSS) as part of the epithelium-off treatment protocol.
    Methods: Sixty-eight porcine eyes, after epithelial debridement, were assigned to six groups in three experimental runs. Group 1 remained untreated. Groups 2-6 received a 16-min application of 0.1% riboflavin/Hydroxypropyl methylcellulose (HPMC) drops, after which Group 3 was exposed to 9 mW/cm
    Results: Application of riboflavin/HPMC solution led to an increase in CCT of 73 ± 14 µm (P < 0.01) after 16 min. All CXL-treated corneas displayed a 2-4 fold greater resistance to collagenase digestion than non-irradiated corneas. There was no difference in resistance between corneas that received no BSS rinse and those that received a 0.25 mL or 1 mL pre-UVA rinse, but each showed a greater level of resistance than those that received a 10 mL pre-UVA rinse (P < 0.05). Confocal microscopy demonstrated reduced stromal riboflavin fluorescence after rinsing.
    Conclusions: All protocols, with and without rinsing, were effective at enhancing the resistance to collagenase digestion, although resistance was significantly decreased, and stromal riboflavin fluorescence reduced with a 10 mL rinse. This suggests that a 10 mL surface rinse can reduce the efficacy of CXL through the dilution of the stromal riboflavin concentration.
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2806610-8
    ISSN 2326-0254
    ISSN 2326-0254
    DOI 10.1186/s40662-024-00375-4
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  7. Article ; Online: Rapid Rescue of Goose Astrovirus Genome via Red/ET Assembly.

    Cui, Daqing / Li, Shujun / Yin, Boxuan / Li, Changyan / Zhang, Lilin / Li, Zexing / Huang, Jinhai

    Food and environmental virology

    2024  

    Abstract: The host-specific infection of Avian Astrovirus (AAstVs) has posed significant challenges to the poultry industry, resulting in substantial economic losses. However, few reports exist on the functional consequences of genome diversity, cross-species ... ...

    Abstract The host-specific infection of Avian Astrovirus (AAstVs) has posed significant challenges to the poultry industry, resulting in substantial economic losses. However, few reports exist on the functional consequences of genome diversity, cross-species infectivity and mechanisms governing virus replication of AAstVs, making it difficult to develop measures to control astrovirus transmission. Reverse genetics technique can be used to study the function of viruses at the molecular level, as well as investigating pathogenic mechanisms and guide vaccine development and disease treatment. Herein, the reverse genetics technique of goose astrovirus GAstV/JS2019 strain was developed based on use of a reconstructed vector including CMV promotor, hammerhead ribozyme (HamRz), hepatitis delta virus ribozyme (HdvRz), and SV40 tail, then the cloned viral genome fragments were connected using Red/ET recombineering. The recombinant rGAstV-JS2019 was readily rescued by transfected the infectious clone plasmid into LMH cells. Importantly, the rescued rGAstV/JS2019 exhibited similar growth kinetics comparable to those of the parental GAstV/JS2019 isolate in cultured cells. Our research results provide an alternative and more effective reverse genetic tool for a detailed understanding of viral replication, pathogenic mechanisms, and molecular mechanisms of evolution.
    Language English
    Publishing date 2024-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2487173-4
    ISSN 1867-0342 ; 1867-0334
    ISSN (online) 1867-0342
    ISSN 1867-0334
    DOI 10.1007/s12560-024-09593-4
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  8. Article: Cell-Penetrating Peptide-Based Delivery of Macromolecular Drugs: Development, Strategies, and Progress.

    Sun, Zhe / Huang, Jinhai / Fishelson, Zvi / Wang, Chenhui / Zhang, Sihe

    Biomedicines

    2023  Volume 11, Issue 7

    Abstract: Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being extensively studied due to their excellent delivery performance. Compared with other delivery vehicles, CPPs hold promise for delivering different types of drugs. Here, ... ...

    Abstract Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being extensively studied due to their excellent delivery performance. Compared with other delivery vehicles, CPPs hold promise for delivering different types of drugs. Here, we review the development process of CPPs and summarize the composition and classification of the CPP-based delivery systems, cellular uptake mechanisms, influencing factors, and biological barriers. We also summarize the optimization routes of CPP-based macromolecular drug delivery from stability and targeting perspectives. Strategies for enhanced endosomal escape, which prolong its half-life in blood, improved targeting efficiency and stimuli-responsive design are comprehensively summarized for CPP-based macromolecule delivery. Finally, after concluding the clinical trials of CPP-based drug delivery systems, we extracted the necessary conditions for a successful CPP-based delivery system. This review provides the latest framework for the CPP-based delivery of macromolecular drugs and summarizes the optimized strategies to improve delivery efficiency.
    Language English
    Publishing date 2023-07-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11071971
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  9. Article ; Online: Influence of Passenger Capacity on Fatigue Life of Gearbox Suspender of the Traction Transmission System in Urban Railway Vehicles

    Xianghe Huang / Jinhai Wang / Jianwei Yang / Yue Zhao / Yuzhu Wang

    Sustainability, Vol 15, Iss 4338, p

    2023  Volume 4338

    Abstract: Fatigue damage is the most dangerous failure behavior for gearbox suspenders in urban railway vehicles, and passenger capacity is crucial to the dynamic load characteristics of the traction transmission system. Therefore, in this paper, a dynamic model ... ...

    Abstract Fatigue damage is the most dangerous failure behavior for gearbox suspenders in urban railway vehicles, and passenger capacity is crucial to the dynamic load characteristics of the traction transmission system. Therefore, in this paper, a dynamic model of the motor car is established, and a numerical simulation is carried out under different speeds and curve radii to investigate the effect of passenger capacity on fatigue life. The research results show that passenger capacity is an essential factor affecting the fatigue life of suspenders. As the vehicle runs at an average speed, the fatigue life of the suspender is 1.07 × 10 6 km when the passenger capacity is 120 people; when there are 240 people, the fatigue life reduction is 60%, while it is 86% at 339 people and 92% at 389 people. The per capita fatigue damage under a straight line is 7.27 × 10 −10 at 20 km/h but 1.23 × 10 −8 at 60 km/h. The per capita fatigue damage under a curved line is 7.18 × 10 −9 in the 600 m curve but 9.00 × 10 −9 in the 400 m curve. It can be concluded that the effect of speed is more significant than the curve radius. This research achievement can provide theoretical support for vehicle design and maintenance decisions.
    Keywords urban railway vehicle ; gearbox suspender ; fatigue life ; passenger capacity ; traction transmission system ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 629
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Oral Immunization with Recombinant

    Li, Huliang / Hua, Deping / Qu, Qingxia / Cao, Hongwei / Feng, Zhehan / Liu, Na / Huang, Jinhai / Zhang, Lei

    Vaccines

    2023  Volume 11, Issue 12

    Abstract: Infectious bursal disease (IBD), as a highly infectious immunosuppressive disease, causes severe economic losses in the poultry industry worldwide. ...

    Abstract Infectious bursal disease (IBD), as a highly infectious immunosuppressive disease, causes severe economic losses in the poultry industry worldwide.
    Language English
    Publishing date 2023-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11121849
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