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Book: Reducing mortality in the perioperative period

Landoni, Giovanni / Ruggeri, Laura / Zangrillo, Alberto

2014

Author's details	Giovanni Landoni ; Laura Ruggeri ; Alberto Zangrillo ed
Language	English
Size	XI, 139 S. : Ill., graph. Darst.
Publisher	Springer
Publishing place	Cham u.a.
Publishing country	Germany
Document type	Book
HBZ-ID	HT018120565
ISBN	978-3-319-02185-0 ; 3-319-02185-0 ; 9783319021867 ; 3319021869
Database	Catalogue ZB MED Medicine, Health

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2014 A 44	available for loan (reading room)	Lesesaal EG

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Article ; Online: “Location, Location, Location”

Laura Gabrielli / Aurora Greta Ruggeri / Massimiliano Scarpa

Land, Vol 12, Iss 1248, p

Fluctuations in Real Estate Market Values after COVID-19 and the War in Ukraine Based on Econometric and Spatial Analysis, Random Forest, and Multivariate Regression

2023 Volume 1248

Abstract: In this research, the authors aim to detect the marginal appreciation of construction and neighbourhood characteristics of property prices at three different time points: before the COVID-19 pandemic, two years after the first COVID-19 alert but before ... ...

Abstract	In this research, the authors aim to detect the marginal appreciation of construction and neighbourhood characteristics of property prices at three different time points: before the COVID-19 pandemic, two years after the first COVID-19 alert but before the War in Ukraine, and one year after the outbreak of the War. The marginal appreciations of the building’s features are analysed for a pilot case study in Northern Italy using a Random Forest feature importance analysis and a Multivariate Regression. Several techniques are integrated into this study, such as computer programming in Python language, multi-parametric value assessment techniques, feature selection procedures, and spatial analysis. The results may represent an interesting ongoing monitoring of how these anomalous events affect the buyer’s willingness to pay for specific characteristics of the buildings, with particular attention to the location features of the neighbourhood and accessibility.
Keywords	market value ; value assessment ; multiple regression ; location ; fixed effects ; computer programming ; Agriculture ; S
Subject code	720
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Amplitude spectrum area measured in real-time during cardiopulmonary resuscitation - How does this technology work?

Ruggeri, Laura / Fumagalli, Francesca / Merigo, Giulia / Magliocca, Aurora / Ristagno, Giuseppe

Resuscitation

2023 Volume 191, Page(s) 109941

Abstract: Amplitude spectrum area (AMSA) is one of the most accurate predictors of defibrillation outcome. Details on functioning and use of the available technology to measure AMSA during cardiopulmonary resuscitation (CPR) in the real clinical scenario are ... ...

Abstract	Amplitude spectrum area (AMSA) is one of the most accurate predictors of defibrillation outcome. Details on functioning and use of the available technology to measure AMSA during cardiopulmonary resuscitation (CPR) in the real clinical scenario are described. During chest compression (CC) pauses for ventilations, AMSA is promptly calculated and values displayed through a modified defibrillator. In addition, real-time AMSA analysis has the additional promise to monitor CPR quality, being AMSA threshold values contingent on CC depth. Future larger studies employing this new technology are now needed to demonstrate the impact of AMSA on survival of cardiac arrest.
MeSH term(s)	Humans ; Cardiopulmonary Resuscitation ; Electric Countershock ; Ventricular Fibrillation ; Amsacrine ; Heart Arrest/therapy
Chemical Substances	Amsacrine (00DPD30SOY)
Language	English
Publishing date	2023-08-23
Publishing country	Ireland
Document type	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	189901-6
ISSN	1873-1570 ; 0300-9572
ISSN (online)	1873-1570
ISSN	0300-9572
DOI	10.1016/j.resuscitation.2023.109941
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Article ; Online: Optimizing defibrillation during cardiac arrest.

Babini, Giovanni / Ruggeri, Laura / Ristagno, Giuseppe

Current opinion in critical care

2022 Volume 27, Issue 3, Page(s) 246–254

Abstract: Purpose of review: Current cardiac arrest guidelines are based on a fixed, time-based defibrillation strategy. Rhythm analysis and shock delivery (if indicated) are repeated every 2 min requiring cyclical interruptions of chest compressions. This ... ...

Abstract	Purpose of review: Current cardiac arrest guidelines are based on a fixed, time-based defibrillation strategy. Rhythm analysis and shock delivery (if indicated) are repeated every 2 min requiring cyclical interruptions of chest compressions. This approach has several downsides, such as the need to temporarily stop cardiopulmonary resuscitation (CPR) for a variable amount of time, thus reducing myocardial perfusion and decreasing the chance of successful defibrillation. A tailored defibrillation strategy should identify treatment priority for each patient, that is chest compressions (CCS) or defibrillation, minimize CCs interruptions, speed up the delivery of early effective defibrillation and reduce the number of ineffective shocks. Recent findings: Real-time ECG analysis (using adaptive filters, new algorithms robust to chest compressions artifacts and shock-advisory algorithms) is an effective strategy to correctly identify heart rhythm during CPR and reduce the hands-off time preceding a shock. Similarly, ventricular fibrillation waveform analysis, that is amplitude spectrum area (AMSA) represents a well established approach to reserve defibrillation in patients with high chance of shock success and postpone it when ventricular fibrillation termination is unlikely. Both approaches demonstrated valuable results in improving cardiac arrest outcomes in experimental and observational study. Summary: Real-time ECG analysis and AMSA have the potential to predict ventricular fibrillation termination, return of spontaneous circulation and even survival, with discretely high confidence. Prospective studies are now necessary to validate these new approaches in the clinical scenario.
MeSH term(s)	Cardiopulmonary Resuscitation ; Electric Countershock ; Electrocardiography ; Heart Arrest/therapy ; Humans ; Observational Studies as Topic ; Prospective Studies ; Ventricular Fibrillation/therapy
Language	English
Publishing date	2022-07-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1235629-3
ISSN	1531-7072 ; 1070-5295
ISSN (online)	1531-7072
ISSN	1070-5295
DOI	10.1097/MCC.0000000000000821
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Article: Does Point-of-Care Ultrasound Affect Fluid Resuscitation Volume in Patients with Septic Shock: A Retrospective Review.

Ablordeppey, Enyo A / Zhao, Amy / Ruggeri, Jeffery / Hassan, Ahmad / Wallace, Laura / Agarwal, Mansi / Stickles, Sean P / Holthaus, Christopher / Theodoro, Daniel

Emergency medicine international

2024 Volume 2024, Page(s) 5675066

Abstract: Background: Fixed, large volume resuscitation with intravenous fluids (IVFs) in septic shock can cause inadvertent hypervolemia, increased medical interventions, and death when unguided by point-of-care ultrasound (POCUS). The primary study objective ... ...

Abstract	Background: Fixed, large volume resuscitation with intravenous fluids (IVFs) in septic shock can cause inadvertent hypervolemia, increased medical interventions, and death when unguided by point-of-care ultrasound (POCUS). The primary study objective was to evaluate whether total IVF volume differs for emergency department (ED) septic shock patients receiving POCUS versus no POCUS. Methods: We conducted a retrospective observational cohort study from 7/1/2018 to 8/31/2021 of atraumatic adult ED patients with septic shock. We agreed upon Results: 304 patients met criteria and 26% (78/304) underwent POCUS. Cardiac POCUS demonstrated reduced ejection fraction in 15.4% of patients. Lung ultrasound showed normal findings in 53% of patients. The POCUS vs. non-POCUS cohorts had statistically significant differences for the following variables: higher median lactate (6.7 [IQR 5.2-8.7] vs. 5.6], Conclusions: Among ED patients with septic shock, POCUS was more likely to be used in sicker patients. Patients who had POCUS were given similar volume of crystalloids although these patients were more critically ill. There were no differences in new oxygen requirement or mortality in the POCUS group compared to the non-POCUS group.
Language	English
Publishing date	2024-05-06
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2596429-X
ISSN	2090-2859 ; 2090-2840
ISSN (online)	2090-2859
ISSN	2090-2840
DOI	10.1155/2024/5675066
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Article: Aging deteriorates the ability to discriminate the weight of an object during an action observation task.

Albergoni, Andrea / Biggio, Monica / Faelli, Emanuela / Ruggeri, Piero / Avanzino, Laura / Bove, Marco / Bisio, Ambra

Frontiers in aging neuroscience

2023 Volume 15, Page(s) 1216304

Abstract: The ability to predict the weight of objects is important for skilled and dexterous manipulation during activities of daily living. The observation of other people moving objects might represent an important source of information on object features and ... ...

Abstract	The ability to predict the weight of objects is important for skilled and dexterous manipulation during activities of daily living. The observation of other people moving objects might represent an important source of information on object features and help to plan the correct motor interaction with it. In aging, an impaired ability to evaluate the object weight might have negative drawbacks in term of the safety of the person. The aim of this study was to investigate the role of aging in the ability to discriminate the object weight during action observation. Twenty older adults (Old) and twenty young subjects (Young) performed a two-interval forced-choice task consisting in the observation of a couple of videos showing an actor moving a box of different weights. The observer had to evaluate which video showed the heavier box. Handgrip strength was acquired from all subjects. Sensitivity analysis was performed and psychometric curves were built on participants' responses. The results showed a diminished sensitivity in the object weight discrimination in Old than in Young group. The analysis of the psychometric curves revealed that this impairment pertained both the light and heavy boxes and the minimum difference to discriminate different weights was greater in Old than in Young. At last, the sensitivity and the discrimination ability significantly correlated with individuals' handgrip strength. These findings allow us to deeply characterize the impairments older adults have in discriminating the weight of an object moved by another individual.
Language	English
Publishing date	2023-08-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2558898-9
ISSN	1663-4365
ISSN	1663-4365
DOI	10.3389/fnagi.2023.1216304
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Article ; Online: Sensorimotor expertise influences perceptual weight judgments during observation of a sport-specific gesture.

Albergoni, Andrea / Biggio, Monica / Faelli, Emanuela / Pesce, Andrea / Ruggeri, Piero / Avanzino, Laura / Bove, Marco / Bisio, Ambra

Frontiers in sports and active living

2023 Volume 5, Page(s) 1148812

Abstract: This study aimed to investigate the role of sensorimotor expertise in evaluating relative weight of a lifted object during the observation of a sport-specific gesture, namely the deadlift. Fifty-six participants, assigned to three groups according to ... ...

Abstract	This study aimed to investigate the role of sensorimotor expertise in evaluating relative weight of a lifted object during the observation of a sport-specific gesture, namely the deadlift. Fifty-six participants, assigned to three groups according to their experience in weight lifting, powerlifters, CrossFit® practitioners and naïve participants (controls), performed a perceptual weight judgments task. Participants observed videos showing a powerlifter executing a deadlift at the 80%, 90% and 100% of 1 repetition maximum (1RM) and answered a question about the weight of the lifted object. Participants' response accuracy and variability were evaluated. Findings showed that powerlifters were more accurate than controls. No differences appeared between powerlifter and CrossFit® practitioners, and between CrossFit® practitioners and controls. Response variability was similar in the three groups. These findings suggest that a fine sensorimotor expertise specific for the observed gesture is crucial to detect the weight of the object displayed in the observed movement, since it might allow detecting small changes in the observed movement kinematics, which we speculate are at the basis of the object weight recognition.
Language	English
Publishing date	2023-06-22
Publishing country	Switzerland
Document type	Journal Article
ISSN	2624-9367
ISSN (online)	2624-9367
DOI	10.3389/fspor.2023.1148812
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Article ; Online: Eating behaviour, physical activity and lifestyle of Italian children during lockdown for COVID-19.

Censi, Laura / Ruggeri, Stefania / Galfo, Myriam / Buonocore, Pasquale / Roccaldo, Romana

International journal of food sciences and nutrition

2021 Volume 73, Issue 1, Page(s) 93–105

Abstract: In March 2020 Italy went into lockdown due to COVID-19 pandemic and children changed rapidly their lifestyles with possible negative effects on their health status. An online survey collected data on eating habits, physical activity, perception/behaviour ...

Abstract	In March 2020 Italy went into lockdown due to COVID-19 pandemic and children changed rapidly their lifestyles with possible negative effects on their health status. An online survey collected data on eating habits, physical activity, perception/behaviour of 1027 Italian 2-11 years children during lockdown. The chi-square test was applied to test differences in proportions. Results showed a tendency of eating behaviour to worsen as children age and by areas. Only 32.3% of the children had high adherence to Mediterranean Diet, with better scores in 2-5 years children. 78.1% of the children stopped their habitual physical activity, with higher percentage among 6-11 and in Northern children; only 51.8% maintained some activities at home, playing mainly movement games/sports. Children spent more time on devices, missed school and friends, being more bored and less creative. This framework highlights the growing need for strategies to preserve children's health in this and future pandemics.
MeSH term(s)	COVID-19 ; Communicable Disease Control ; Exercise ; Feeding Behavior ; Humans ; Italy ; Life Style ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2021-05-12
Publishing country	England
Document type	Journal Article
ZDB-ID	1121877-0
ISSN	1465-3478 ; 0963-7486
ISSN (online)	1465-3478
ISSN	0963-7486
DOI	10.1080/09637486.2021.1921127
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Article ; Online: Performance and effectiveness of step progressive care pathways within mental health supported accommodation services in Italy.

Martinelli, Alessandra / Iozzino, Laura / Pozzan, Tecla / Cristofalo, Doriana / Bonetto, Chiara / Ruggeri, Mirella

Social psychiatry and psychiatric epidemiology

2022 Volume 57, Issue 5, Page(s) 939–952

Abstract: Background: In Italy, a growing number of people with severe mental illness (SMI) require care in residential facilities (RFs), a key component of the care pathway. However, despite their development, studies about resident samples have been very few.!## ...

Abstract	Background: In Italy, a growing number of people with severe mental illness (SMI) require care in residential facilities (RFs), a key component of the care pathway. However, despite their development, studies about resident samples have been very few. Aims: This study, the VALERE-REC Study (eVALuation of outcomE in Residential-use of clinical data with REsearch objeCtives) aims to identify the characteristics that increase the probability to move patients living in RFs to a more independent setting. Methods: A survey involved 167 patients hosted in 25 RFs of the Verona Mental Health Department. Forty-five patients were residents (27%) in Comunità Terapeutico Riabilitativa Protetta (CTRP); 56 (34%) in Comunità Alloggio (CA), 14 (8%) in Gruppo Appartamento Protetto (GAP), 52 (31%) in Comunità Alloggio Estensiva (CAE). They were assessed for their care pathway after 30-months. The Quality Indicators for Rehabilitative Care-Supported Accommodation (QuIRC-SA) evaluated the quality of 19/25 (76%) RFs. Descriptive analyses were done. Results: According to the mission stated by the Veneto Region guidelines, RFs hosted patients with different needs and clinical profiles. The mean stay was longer than expected, most patients were unemployed, unmet needs were related to self-management and patient's social contacts, and recovery-oriented practices were not implemented. Conclusions: Despite the appropriate admission of patients in different RFs considering their psychopathology, functioning, and needs, the progressive step care pathway did not result effectively pursued. To improve the effectiveness of residential interventions a major task should be to focus on the acquisition of the necessary skills to live independently.
MeSH term(s)	Critical Pathways ; Humans ; Mental Disorders/psychology ; Mental Disorders/therapy ; Mental Health ; Mental Health Services ; Residential Facilities
Language	English
Publishing date	2022-01-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	623071-4
ISSN	1433-9285 ; 0037-7813 ; 0933-7954
ISSN (online)	1433-9285
ISSN	0037-7813 ; 0933-7954
DOI	10.1007/s00127-021-02128-3
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Article ; Online: Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte.

Adams, Laura / Liu, Ying / Durrant, Barbara / Ruggeri, Elena / Young, Carly / Krisher, Rebecca / Polejaeva, Irina

Journal of visualized experiments : JoVE

2022 , Issue 185

Abstract: Interspecies somatic cell nuclear transfer (iSCNT) may be used to rescue endangered species, but two distinct populations of mitochondrial DNA (mtDNA) exist within the reconstructed embryo: one within the recipient ooplasm and one within the donor ... ...

Abstract	Interspecies somatic cell nuclear transfer (iSCNT) may be used to rescue endangered species, but two distinct populations of mitochondrial DNA (mtDNA) exist within the reconstructed embryo: one within the recipient ooplasm and one within the donor somatic cell. This mitochondrial heteroplasmy can lead to developmental issues in the embryo and the fetus. Handmade cloning protocols include oocyte bisection, which can be used to decrease the mtDNA copy number, reducing the degree of mitochondrial heteroplasmy in a reconstructed embryo. Centrifugation of denuded, mature bovine oocytes produced a visible mitochondria-dense fraction at one pole of the oocyte. Oocytes' zonae pellucidae were removed by exposure to a pronase solution. Bisection was performed using a microblade to remove the visible mitochondria fraction. qPCR was used to quantify the mtDNA present in DNA samples extracted from whole oocytes and bisected ooplasts, providing a comparison of mtDNA copy numbers before and after bisection. Copy numbers were calculated using cycle threshold values, a standard curve's regression line formula, and a ratio that included the respective sizes of mtDNA PCR products and genomic PCR products. One bovine oocyte had an average mtDNA copy number (± standard deviation) of 137,904 ± 94,768 (n = 38). One mitochondria-depleted ooplast had an average mtDNA copy number of 8,442 ± 13,806 (n = 33). Average mtDNA copies present in a mitochondria-rich ooplast were 79,390 ± 58,526 mtDNA copies (n = 28). The differences between these calculated averages indicate that the centrifugation and subsequent bisection can significantly decrease the mtDNA copy numbers present in the mitochondria-depleted ooplast when compared to the original oocyte (P < 0.0001, determined by one-way ANOVA). The reduction in mtDNA should decrease the degree of mitochondrial heteroplasmy in a reconstructed embryo, possibly fostering standard embryonic and fetal development. Supplementation with mitochondrial extract from the somatic donor cell may also be essential to achieve successful embryonic development.
MeSH term(s)	Animals ; Cattle/genetics ; Cloning, Organism/methods ; DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Female ; Mitochondria/genetics ; Mitochondria/metabolism ; Nuclear Transfer Techniques ; Oocytes ; Pregnancy
Chemical Substances	DNA, Mitochondrial
Language	English
Publishing date	2022-07-06
Publishing country	United States
Document type	Journal Article ; Video-Audio Media
ZDB-ID	2259946-0
ISSN	1940-087X ; 1940-087X
ISSN (online)	1940-087X
ISSN	1940-087X
DOI	10.3791/64060
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