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  1. Article: Recycling of plastic wastes generated from COVID-19: A comprehensive illustration of type and properties of plastics with remedial options

    Abhilash / Inamdar, Isiri

    Science of the total environment. 2022 Sept. 10, v. 838

    2022  

    Abstract: ... on the methods, strategies have been enumerated for combination of different methods, vis-à-vis studying ...

    Abstract Plastic has contributed enormously to the healthcare sector and towards public health safety during the COVID-19 pandemic. With the frequent usage of plastic-based personal protective equipment (PPEs) (including face masks, gloves, protective body suits, aprons, gowns, face shields, surgical masks, and goggles), by frontline health workers, there has been a tremendous increase in their manufacture and distribution. Different types of plastic polymers are used in the manufacture of this equipment, depending upon their usage. However, since a majority of these plastics are still single-use plastics (SUP), they are not at all eco-friendly and end up generating large quantities of plastic waste. The overview presents the various available and practiced methods in vogue for disposal cum treatment of these highly contaminated plastic wastes. Among the current methods of plastic waste disposal, incineration and land filling are the most common ones, but both these methods have their negative impacts on the environment. Alongside, numerous methods that can be used to sterilize them before any treatment have been discussed. There are several new sorting technologies, to help produce purer polymers that can be made to undergo thermal or chemical treatments. Microbial degradation is one such novel method that is under the spotlight currently and being studied extensively, because of its ecological advantages, cost-effectiveness, ease of use, and maintenance. In addition to the deliberations on the methods, strategies have been enumerated for combination of different methods, vis-à-vis studying the life cycle assessment towards a more circular economy in handling this menace to protect mankind.
    Keywords COVID-19 infection ; biodegradation ; circular economy ; cost effectiveness ; environment ; health services ; humans ; life cycle assessment ; manufacturing ; plastics ; public health ; safety equipment ; waste disposal ; wastes
    Language English
    Dates of publication 2022-0910
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.155895
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Recycling of plastic wastes generated from COVID-19: A comprehensive illustration of type and properties of plastics with remedial options.

    Abhilash / Inamdar, Isiri

    The Science of the total environment

    2022  Volume 838, Issue Pt 1, Page(s) 155895

    Abstract: ... on the methods, strategies have been enumerated for combination of different methods, vis-à-vis studying ...

    Abstract Plastic has contributed enormously to the healthcare sector and towards public health safety during the COVID-19 pandemic. With the frequent usage of plastic-based personal protective equipment (PPEs) (including face masks, gloves, protective body suits, aprons, gowns, face shields, surgical masks, and goggles), by frontline health workers, there has been a tremendous increase in their manufacture and distribution. Different types of plastic polymers are used in the manufacture of this equipment, depending upon their usage. However, since a majority of these plastics are still single-use plastics (SUP), they are not at all eco-friendly and end up generating large quantities of plastic waste. The overview presents the various available and practiced methods in vogue for disposal cum treatment of these highly contaminated plastic wastes. Among the current methods of plastic waste disposal, incineration and land filling are the most common ones, but both these methods have their negative impacts on the environment. Alongside, numerous methods that can be used to sterilize them before any treatment have been discussed. There are several new sorting technologies, to help produce purer polymers that can be made to undergo thermal or chemical treatments. Microbial degradation is one such novel method that is under the spotlight currently and being studied extensively, because of its ecological advantages, cost-effectiveness, ease of use, and maintenance. In addition to the deliberations on the methods, strategies have been enumerated for combination of different methods, vis-à-vis studying the life cycle assessment towards a more circular economy in handling this menace to protect mankind.
    MeSH term(s) COVID-19 ; Humans ; Pandemics ; Plastics ; Recycling ; Refuse Disposal
    Chemical Substances Plastics
    Language English
    Publishing date 2022-05-12
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.155895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A two-process model of Drosophila sleep reveals an inter-dependence between circadian clock speed and the rate of sleep pressure decay.

    Abhilash, Lakshman / Shafer, Orie Thomas

    Sleep

    2023  Volume 47, Issue 2

    Abstract: ... For four decades, Borbély and Daan's two-process model has provided a powerful framework for understanding ...

    Abstract Sleep is controlled by two processes-a circadian clock that regulates its timing and a homeostat that regulates the drive to sleep. Drosophila has been an insightful model for understanding both processes. For four decades, Borbély and Daan's two-process model has provided a powerful framework for understanding sleep regulation. However, the field of fly sleep has not employed such a model as a framework for the investigation of sleep. To this end, we have adapted the two-process model to the fly and established its utility by showing that it can provide empirically testable predictions regarding the circadian and homeostatic control of fly sleep. We show that the ultradian rhythms previously reported for loss-of-function clock mutants in the fly are robustly detectable and a predictable consequence of a functional sleep homeostat in the absence of a functioning circadian system. We find that a model in which the circadian clock speed and homeostatic rates act without influencing each other provides imprecise predictions regarding how clock speed influences the strength of sleep rhythms and the amount of daily sleep. We also find that quantitatively good fits between empirical values and model predictions were achieved only when clock speeds were positively correlated with rates of decay of sleep pressure. Our results indicate that longer sleep bouts better reflect the homeostatic process than the current definition of sleep as any inactivity lasting 5 minutes or more. This two-process model represents a powerful framework for work on the molecular and physiological regulation of fly sleep.
    MeSH term(s) Animals ; Drosophila/physiology ; Circadian Clocks/genetics ; Circadian Rhythm/genetics ; Sleep/physiology ; Drosophila Proteins/genetics
    Chemical Substances Drosophila Proteins
    Language English
    Publishing date 2023-11-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsad277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Prosthetics in urology: Current status and future directions.

    Cheriyan, Abhilash

    Indian journal of urology : IJU : journal of the Urological Society of India

    2022  Volume 39, Issue 1, Page(s) 12–20

    Abstract: ... newer indications such as Peyronie's disease and gender-affirming surgeries. This review, based ... on the Urological Society of India's Best Essay Award 2022, aims to elaborate on the advances in the field ...

    Abstract The field of genitourinary prosthetics has evolved rapidly to become the standard of care for conditions such as incontinence and refractory erectile dysfunction. Its scope has expanded to encompass newer indications such as Peyronie's disease and gender-affirming surgeries. This review, based on the Urological Society of India's Best Essay Award 2022, aims to elaborate on the advances in the field of urological prosthetics in the past 20 years as well as to provide an insight into ongoing research and what one can expect to see in the next decade, particularly in the area of penile and testicular prosthetics as well as treatment of incontinence. A PubMed and patent search was performed to achieve these objectives. Future considerations include improving acceptance, reliability, making them more accessible for developing countries and improving training and education to improve outcomes.
    Language English
    Publishing date 2022-12-29
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 639268-4
    ISSN 1998-3824 ; 0970-1591
    ISSN (online) 1998-3824
    ISSN 0970-1591
    DOI 10.4103/iju.iju_90_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: West coast India’s rainfall is becoming more convective

    A. V. Sreenath / S. Abhilash / P. Vijaykumar / B. E. Mapes

    npj Climate and Atmospheric Science, Vol 5, Iss 1, Pp 1-

    2022  Volume 7

    Abstract: Abstract A disastrous cloudburst and associated floods in Kerala during the 2019 monsoon season raise the hypothesis that rainfall over the west coast of India, much of which is stratiform, may be trending towards being more convective. As a first ... ...

    Abstract Abstract A disastrous cloudburst and associated floods in Kerala during the 2019 monsoon season raise the hypothesis that rainfall over the west coast of India, much of which is stratiform, may be trending towards being more convective. As a first exploration, we sought statistically significant differences in monthly ERA-5 reanalysis data for the monsoon season between two epochs, 1980–1999 and 2000–2019. Results suggest a more convective (deeper, ice-rich) cloud population in recent decades, with patterns illustrated in ERA-5 spatial maps. Deepening of convection, above and beyond its trend in amount, is also indicated by the steeper regression slope of outgoing longwave radiation trends against precipitation than that exhibited in interannual variability. Our reanalysis results are strengthened by related trends manifested in more direct observations from satellite and gauge-based rainfall and a CAPE index from balloon soundings data.
    Keywords Environmental sciences ; GE1-350 ; Meteorology. Climatology ; QC851-999
    Subject code 910
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: A rapid assessment of stubble burning and air pollutants from satellite observations.

    Das, P / Behera, M D / Abhilash, P C

    Tropical ecology

    2023  , Page(s) 1–6

    Abstract: For the last several years, the air quality of India's capital Delhi and surrounding region (NCR ...

    Abstract For the last several years, the air quality of India's capital Delhi and surrounding region (NCR) has been degrading to a very poor and severe category during the autumn season. In addition to the various sources of air pollutants within the NCR region, the stubble burning in Punjab and Haryana states contributes to the poor air quality in this region. The current study employs the Moderate Resolution Imaging Spectroradiometer (MODIS) active fire products and TROPOspheric Monitoring Instrument (TROPOMI) products on carbon monoxide (CO) and nitrogen dioxide (NO
    Language English
    Publishing date 2023-05-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 975741-7
    ISSN 0564-3295
    ISSN 0564-3295
    DOI 10.1007/s42965-022-00291-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Assessing the pulmonary vascular responsiveness to oxygen with proton MRI.

    Kizhakke Puliyakote, Abhilash S / Tedjasaputra, Vincent / Petersen, Gregory M / Sá, Rui Carlos / Hopkins, Susan R

    Journal of applied physiology (Bethesda, Md. : 1985)

    2024  Volume 136, Issue 4, Page(s) 853–863

    Abstract: Ventilation-perfusion matching occurs passively and is also actively regulated through hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly normal subjects, is uncertain. Current evaluation of HPV assesses changes ... ...

    Abstract Ventilation-perfusion matching occurs passively and is also actively regulated through hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly normal subjects, is uncertain. Current evaluation of HPV assesses changes in ventilation-perfusion relationships/pulmonary vascular resistance with hypoxia and is invasive, or unsuitable for patients because of safety concerns. We used a noninvasive imaging-based approach to quantify the pulmonary vascular response to oxygen as a metric of HPV by measuring perfusion changes between breathing 21% and 30%O
    MeSH term(s) Humans ; Young Adult ; Adult ; Middle Aged ; Oxygen ; Protons ; Pulmonary Circulation/physiology ; Hyperoxia ; Papillomavirus Infections ; Lung/physiology ; Hypoxia ; Vasoconstriction/physiology ; Magnetic Resonance Imaging/methods
    Chemical Substances Oxygen (S88TT14065) ; Protons
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00747.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Modulation of Aβ 16-22 aggregation by glucose.

    Jain, Meenal / Sahoo, Abhilash / Matysiak, Silvina

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 6, Page(s) 5038–5044

    Abstract: ... a signature of Alzheimer's disease. Recent studies have reported correlations between Alzheimer's disease and ...

    Abstract The self-assembly of amyloid-beta (Aβ) peptides into fibrillar structures in the brain is a signature of Alzheimer's disease. Recent studies have reported correlations between Alzheimer's disease and type-2 diabetes. Structurally, hyperglycemia induces covalent protein crosslinkings by advanced glycation end products (AGE), which can affect the stability of Aβ oligomers. In this work, we leverage physics-based coarse-grained molecular simulations to probe alternate thermodynamic pathways that affect peptide aggregation propensities at varying concentrations of glucose molecules. Similar to previous experimental reports, our simulations show a glucose concentration-dependent increase in Aβ aggregation rates, without changes in the overall secondary structure content. We discovered that glucose molecules prefer partitioning onto the aggregate-water interface at a specific orientation, resulting in a loss of molecular rotational entropy. This effectively hastens the aggregation rates, as peptide self-assembly can reduce the available surface area for peptide-glucose interactions. This work introduces a new thermodynamic-driven pathway, beyond chemical cross-linking, that can modulate Aβ aggregation.
    MeSH term(s) Humans ; Alzheimer Disease/metabolism ; Glucose ; Amyloid beta-Peptides/chemistry ; Protein Structure, Secondary ; Thermodynamics ; Peptide Fragments/metabolism
    Chemical Substances Glucose (IY9XDZ35W2) ; Amyloid beta-Peptides ; Peptide Fragments
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp04494g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Insights on the structural characteristics and molecular dynamic studies of methyl vanillin Schiff base bio-compounds.

    Asha, S / Sandhya, K S / Abhilash, A / Achuthsankar, Nair S / Suma, S / Sudarsanakumar, M R

    Journal of biomolecular structure & dynamics

    2023  , Page(s) 1–15

    Abstract: A new crystalline form of Schiff base, ...

    Abstract A new crystalline form of Schiff base,
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2259492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Point of Care Ultrasonography Enhanced Physical Examination: A Nephrologist's Perspective.

    Koratala, Abhilash

    The American journal of medicine

    2020  Volume 133, Issue 7, Page(s) e384–e385

    MeSH term(s) Humans ; Internal Medicine ; Internship and Residency ; Nephrologists ; Point-of-Care Systems ; Ultrasonography
    Language English
    Publishing date 2020-06-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2020.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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