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  1. Article ; Online: Remote ischemic preconditioning: Lung protection in the time of a pandemic?

    Camara-Lemarroy, Carlos R

    Journal of clinical anesthesia

    2020  Volume 66, Page(s) 109920

    MeSH term(s) Humans ; Ischemic Preconditioning ; Lung ; Pandemics
    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country United States
    Document type Letter
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2020.109920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Prolonged Transient Global Amnesia: Part of the Clinical Spectrum or a Separate Disease Entity?

    Yong, Heather Y F / Camara-Lemarroy, Carlos R

    The Neurohospitalist

    2023  Volume 13, Issue 4, Page(s) 425–428

    Abstract: Background: Transient global amnesia (TGA) is the prototypical neurologic disease for acute-onset reversible amnesia. It is currently defined by resolution of symptoms within 24-hours. In this case report we describe an atypical case of prolonged TGA, ... ...

    Abstract Background: Transient global amnesia (TGA) is the prototypical neurologic disease for acute-onset reversible amnesia. It is currently defined by resolution of symptoms within 24-hours. In this case report we describe an atypical case of prolonged TGA, emphasizing our current lack of knowledge surrounding this disease entity and its pathophysiology.
    Results: A 66-year old female presented acutely with profound anterograde amnesia and variable retrograde amnesia with no inciting event. A thorough workup to exclude alternative causes of amnesia (including computed tomography angiogram and electroencephalogram) was normal. Her magnetic resonance imaging was consistent with TGA, with punctate diffusion restriction changes bilaterally in the hippocampi. She was also mildly hypoxemic with no discernible cause. She was ultimately diagnosed with TGA although her diagnosis remains controversial as her symptoms persisted for 72-hours.
    Conclusion: Our patients clinical and imaging features (apart from her protracted time-course and hypoxemia) were in keeping with a diagnosis of TGA. The association of hypoxemia, COVID-19, obstructive sleep apnea, and the development of TGA remains to be elucidated. Although the underlying pathophysiology for TGA is unknown several mechanisms have been postulated including cortical spreading depression and reversible hypoxic-ischemic injury. The time course for symptom resolution, could be an important clue in discerning the pathophysiology of TGA on an individual basis. Importantly, a clinician should not be deterred by amnestic symptoms lasting >24-hours, if the patients clinical/radiologic presentation is consistent with TGA.
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2629083-2
    ISSN 1941-8752 ; 1941-8744
    ISSN (online) 1941-8752
    ISSN 1941-8744
    DOI 10.1177/19418744231184120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Can Our Guts Tell Us Anything About MS?

    Camara-Lemarroy, Carlos R

    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    2019  Volume 14, Issue 3, Page(s) 367–368

    MeSH term(s) Gastrointestinal Microbiome ; Humans ; Lymphocyte Activation ; Monocytes ; Multiple Sclerosis
    Language English
    Publishing date 2019-02-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2227405-4
    ISSN 1557-1904 ; 1557-1890
    ISSN (online) 1557-1904
    ISSN 1557-1890
    DOI 10.1007/s11481-019-09841-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Kikuchi-Fujimoto disease preceding diagnosis of relapsing-remitting multiple sclerosis.

    Mahjoub, Yasamin / Nickel, Alicia / Wong, Michael D / Camara-Lemarroy, Carlos R

    Acta neurologica Belgica

    2023  

    Language English
    Publishing date 2023-04-13
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-023-02270-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sudden sensorineural hearing loss as an initial presentation in multiple sclerosis.

    Yong, Heather Y F / Camara-Lemarroy, Carlos R

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2022  Volume 105, Page(s) 129–130

    MeSH term(s) Hearing Loss, Sensorineural/diagnosis ; Hearing Loss, Sensorineural/etiology ; Hearing Loss, Sudden/diagnosis ; Hearing Loss, Sudden/etiology ; Humans ; Multiple Sclerosis/diagnosis ; Multiple Sclerosis/diagnostic imaging
    Language English
    Publishing date 2022-09-28
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2022.09.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Trigeminal nerve enhancement in multiple sclerosis without clinical correlation presents a mystery: a case report.

    Yong, Heather Y F / Roberts, Jodie / Camara-Lemarroy, Carlos R

    Acta neurologica Belgica

    2022  Volume 122, Issue 5, Page(s) 1399–1401

    MeSH term(s) Humans ; Magnetic Resonance Imaging ; Multiple Sclerosis/complications ; Multiple Sclerosis/diagnostic imaging ; Trigeminal Nerve/diagnostic imaging ; Trigeminal Neuralgia/etiology
    Language English
    Publishing date 2022-06-27
    Publishing country Italy
    Document type Case Reports ; Letter
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-022-02013-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Neuro-Behcet's Presenting as a Tumefactive Brainstem Mass.

    Yong, Heather Y F / Camara-Lemarroy, Carlos R / Alikhani, Katayoun

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2022  Volume 50, Issue 5, Page(s) 787–789

    MeSH term(s) Humans ; Brain Stem/diagnostic imaging ; Behcet Syndrome/complications ; Behcet Syndrome/diagnosis ; Magnetic Resonance Imaging
    Language English
    Publishing date 2022-10-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2022.298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Glucose and stroke: What about glycemic variability?

    Camara-Lemarroy, Carlos R

    Journal of the neurological sciences

    2017  Volume 373, Page(s) 242–243

    MeSH term(s) Blood Glucose ; Glucose ; Humans ; Hyperglycemia ; Stroke
    Chemical Substances Blood Glucose ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2017-02-15
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2017.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Simple parameters from complete blood count predict lymphopenia, adverse effects and efficacy in people with MS treated with dimethyl fumarate.

    Baeva, Maria-Elizabeth / Metz, Luanne M / Greenfield, Jamie / Camara-Lemarroy, Carlos R

    Multiple sclerosis and related disorders

    2023  Volume 74, Page(s) 104699

    Abstract: Background: Dimethyl fumarate (DMF) is a first-line oral therapy for relapsing-remitting multiple sclerosis (RRMS). This retrospective study aims to determine the utility of routine complete blood counts (CBC) in predicting lymphopenia, adverse effects ... ...

    Abstract Background: Dimethyl fumarate (DMF) is a first-line oral therapy for relapsing-remitting multiple sclerosis (RRMS). This retrospective study aims to determine the utility of routine complete blood counts (CBC) in predicting lymphopenia, adverse effects and efficacy in a real-world clinical setting.
    Methods: The Calgary Multiple Sclerosis (MS) Clinic manages over 1800 people with MS on disease-modifying therapies (DMT). Data of patients with relapsing-remitting MS (pwMS) who initiated DMF between July 1, 2013 and December 31, 2014 were included. Patients were followed for one year. DMT use is carefully monitored and pwMS need a screening CBC and have regular CBCs done at follow-up. Demographic, clinical, MRI and relapse information are collected prospectively in a clinic database. We analyzed CBCs at baseline and month 3.
    Results: We identified 139 pwMS in the study period who started DMF. Median follow-up time on-drug was 12 (0.16-12) months. In our study, 15.8% of pwMS developed lymphopenia grade 2 or higher. Baseline lymphocyte counts and older age were significant predictors of lymphopenia. Higher baseline eosinophil counts predicted flushing/gastrointestinal adverse effects, and higher baseline monocyte counts were predictive of breakthrough disease activity. Neutrophil and platelet to lymphocyte ratios, markers that have been associated with overall mortality in the general population, were increased at month 3.
    Conclusions: Routinely obtained CBCs during the screening and monitoring of people with MS starting DMF offer clinically useful information and generate interesting hypotheses. Age and baseline lymphocyte counts are reinforced as clinically useful predictors of lymphopenia. Our novel findings that baseline eosinophil and monocyte counts could offer insights into usual adverse effects and efficacy, respectively, should be further investigated as a potentially new set of biomarkers.
    MeSH term(s) Humans ; Dimethyl Fumarate/adverse effects ; Immunosuppressive Agents/adverse effects ; Retrospective Studies ; Lymphopenia/chemically induced ; Multiple Sclerosis, Relapsing-Remitting/diagnostic imaging ; Multiple Sclerosis, Relapsing-Remitting/drug therapy ; Multiple Sclerosis, Relapsing-Remitting/chemically induced ; Leukopenia ; Lymphocyte Count ; Drug-Related Side Effects and Adverse Reactions/drug therapy ; Thrombocytopenia/chemically induced ; Multiple Sclerosis/drug therapy
    Chemical Substances Dimethyl Fumarate (FO2303MNI2) ; Immunosuppressive Agents
    Language English
    Publishing date 2023-04-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2645330-7
    ISSN 2211-0356 ; 2211-0348
    ISSN (online) 2211-0356
    ISSN 2211-0348
    DOI 10.1016/j.msard.2023.104699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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