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  1. Article: Pressures, indexes and peripheral arterial disease: Time to rethink our approach?

    Westby, Daniel / Doolan, Nathalie N / Walsh, Stewart R

    Annals of the Academy of Medicine, Singapore

    2022  Volume 51, Issue 3, Page(s) 134–135

    MeSH term(s) Humans ; Peripheral Arterial Disease/epidemiology
    Language English
    Publishing date 2022-03-31
    Publishing country Singapore
    Document type Editorial ; Comment
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.202263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Report of Penile Mondor's Disease After Mechanochemical Ablation and Adjunct Foam Sclerotherapy of Bilateral Lower Extremity Truncal Incompetence.

    Foley, Megan Power / Westby, Daniel / Walsh, Stewart R

    Vascular and endovascular surgery

    2023  Volume 57, Issue 5, Page(s) 494–496

    Abstract: Introduction: Mondor's disease of the penis, or superficial thrombophlebitis affecting penile veins, is a rare condition. Common causes include prothombotic states, venous stasis or excessive manipulation. The literature includes one case report of ... ...

    Abstract Introduction: Mondor's disease of the penis, or superficial thrombophlebitis affecting penile veins, is a rare condition. Common causes include prothombotic states, venous stasis or excessive manipulation. The literature includes one case report of Mondor's Disease after endovenous laser ablation and foam sclerotherapy and a case series after open saphenofemoral junction ligation. However, there have been no noted cases of this rare complication after mechanochemical ablation of the GSV.
    Case details: A 50-year-old man with bilateral great saphenous venous incompetence had truncal mechanochemical ablation of both above-knee GSV segments with the Clarivein
    Conclusions: Vascular surgeons should be aware that this rare albeit self-limiting thrombotic complication can occur after endovenous mechanochemical ablation of the great saphenous vein with adjunct foam sclerotherapy, particularly as this procedure is performed very frequently. Interestingly, the majority of reported cases have occurred after bilateral interventions. The patients can be reassured that their symptoms will likely settle and the use of anti-thrombotic therapy is largely at the surgeon's discretion.
    MeSH term(s) Male ; Humans ; Middle Aged ; Sclerotherapy/adverse effects ; Sclerotherapy/methods ; Varicose Veins/diagnostic imaging ; Varicose Veins/surgery ; Treatment Outcome ; Thrombophlebitis/complications ; Laser Therapy ; Lower Extremity ; Saphenous Vein/diagnostic imaging ; Saphenous Vein/surgery ; Venous Insufficiency/diagnostic imaging ; Venous Insufficiency/surgery
    Language English
    Publishing date 2023-01-22
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2076272-0
    ISSN 1938-9116 ; 1538-5744
    ISSN (online) 1938-9116
    ISSN 1538-5744
    DOI 10.1177/15385744231154329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: An audit of secondary prevention for peripheral arterial disease in primary care - scope for improved collaboration between vascular surgery and general practitioners.

    Foley, Megan Power / Tubassam, Muhammad / Walsh, Stewart R

    Irish journal of medical science

    2023  Volume 192, Issue 6, Page(s) 3007–3010

    Abstract: Background: Symptomatic peripheral arterial disease (PAD) is a common cause for referral from primary care to vascular surgery. Best medical therapy (BMT), encompassing anti-platelets, statins, smoking cessation, blood pressure and glycaemic control, is ...

    Abstract Background: Symptomatic peripheral arterial disease (PAD) is a common cause for referral from primary care to vascular surgery. Best medical therapy (BMT), encompassing anti-platelets, statins, smoking cessation, blood pressure and glycaemic control, is a cornerstone of PAD management. However, these easily modifiable risk factors are often left unaddressed between referral and clinic review.
    Methods: A prospective audit of electronic 'Healthlink' referrals by GPs to the vascular department for symptomatic PAD between July 2021 and June 2022 was performed. Referrals were individually reviewed for demographics, symptoms, medical history, smoking status and medications. An information leaflet on BMT was posted to all GP practices in the Soalta region as part of an educational intervention, with plans to re-audit after 6 months.
    Results: One-hundred-and-seventy referrals were analysed. The median age was 68.5 years (range 33-94) and 69% (n = 117) were male. The typical vasculopath comorbidity profile was noted. Fifty-two percent (n = 88) were referred with claudication-type pain and 25% (n = 43) with critical limb ischaemia (CLI). Twenty-eight percent (n = 33) were active smokers and 31% (n = 36) had no smoking status documented. Regarding BMT, only 34.5% (n = 40) and 52% (n = 60) were on anti-platelets and statins, respectively. Suspected CLI was not significantly associated with BMT prescription at referral (p = 0.664). Only eleven referral letters mentioned risk factor optimisation.
    Conclusions: Our first-cycle results identified significant scope for improvement in community-based risk factor modification for PAD referrals. We aim to continue supporting and educating our colleagues that effective medical management can start safely in primary care and further explore the barriers preventing this.
    MeSH term(s) Male ; Humans ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Female ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; General Practitioners ; Secondary Prevention ; Peripheral Arterial Disease/prevention & control ; Peripheral Arterial Disease/surgery ; Risk Factors ; Vascular Surgical Procedures ; Primary Health Care
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2023-04-26
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-023-03362-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Letter to the Editor Regarding "Use of Embolectomy With Local Anesthesia for Anticoagulation Failure in Radial Artery Thrombosis" by Yilmaz et al.

    Keohane, Colum R / Walsh, Stewart R

    Journal of cardiovascular pharmacology and therapeutics

    2020  Volume 26, Issue 1, Page(s) 100

    MeSH term(s) Anesthesia, Local ; Anticoagulants ; Embolectomy ; Humans ; Radial Artery ; Thrombosis
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2020-08-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1329372-2
    ISSN 1940-4034 ; 1074-2484
    ISSN (online) 1940-4034
    ISSN 1074-2484
    DOI 10.1177/1074248420951142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pharmacological Thromboprophylaxis for VTE Post-Endovenous Ablation of Varicose Veins: Network Meta-Analysis.

    Westby, Daniel / Gasior, Sara / Twyford, Mark / Power Foley, Megan / Lowery, Aoife / Walsh, Stewart R

    Vascular and endovascular surgery

    2024  , Page(s) 15385744241245079

    Abstract: Objective: Endovenous ablation has revolutionized treatment of varicose vein surgery but is associated with a risk of venous thromboembolism. There is no consensus regarding anticoagulation protocols for these patients. This network meta-analysis (NMA) ... ...

    Abstract Objective: Endovenous ablation has revolutionized treatment of varicose vein surgery but is associated with a risk of venous thromboembolism. There is no consensus regarding anticoagulation protocols for these patients. This network meta-analysis (NMA) aims to identify which anticoagulant is optimal in this cohort for clot prevention with minimal risk of adverse bleeding events.
    Methods: Library databases were searched for studies where patients were treated with one or more anticoagulants following endovenous ablation for varicose veins. The methodological quality of included studies was quantified using the Risk of Bias (ROB) assessment tools. Findings were reported using the meta-analysis of observational studies in epidemiology (MOOSE) checklist. Statistical analysis was carried out using metainsight (rpackage).
    Results: Observational data on just under 1500 patients prescribed post ablation anticoagulation (Rivaroxaban, Enoxaparin, Fondaparinux) were analyzed. Patient characteristics were comparable across the cohorts. 81 thrombotic and 40 minor bleeding events occurred in total. Overall rivaroxaban is found to be superior to the other agents.
    Conclusions: This NMA indicates that prophylactic rivaroxaban is the highest ranked anticoagulant for thromboprophylaxis in patients post endovenous ablation for varicose veins, with a low risk of adverse bleeding. The choice whether to anticoagulate these patients is likely to remain at the discretion of the treating clinician.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2076272-0
    ISSN 1938-9116 ; 1538-5744
    ISSN (online) 1938-9116
    ISSN 1538-5744
    DOI 10.1177/15385744241245079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Sensitivity Analysis Does Not Alter Conclusions.

    Foley, Megan Power / Walsh, Stewart R / Doolan, Nathalie / Vulliamy, Paul / McMonagle, Morgan / Aylwin, Christopher

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2023  Volume 67, Issue 3, Page(s) 520–522

    Language English
    Publishing date 2023-12-15
    Publishing country England
    Document type Letter
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2023.12.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Exertional Dyspnoea responses reported in the Dyspnoea Challenge and measures of disease severity in COPD.

    Aitken, Craig R / Walsh, James R / Stewart, Glenn M / Sabapathy, Surendran / Adams, Lewis / Morris, Norman R

    Respiratory physiology & neurobiology

    2022  Volume 304, Page(s) 103941

    Abstract: Background: The Dyspnoea Challenge has been developed to facilitate the field-based measure of exertional dyspnoea(ED). To further validate the test, we aimed to; investigate the relationship between end-exercise ED, generated by a fixed-intensity ... ...

    Abstract Background: The Dyspnoea Challenge has been developed to facilitate the field-based measure of exertional dyspnoea(ED). To further validate the test, we aimed to; investigate the relationship between end-exercise ED, generated by a fixed-intensity Dyspnoea Challenge(DC
    Methods: Thirty-two individuals (15 female) with COPD (GOLD II-IV) (age: 69.7 ± 9.4 yrs; FEV
    Results: End-exercise ED measured during the DC
    Conclusions: The Dyspnoea Challenge is correlated to different parameters of disease severity and produces a similar physiological and ED response to that of the 6MWT with the added benefit of being appropriate for longitudinal assessment of ED.
    MeSH term(s) Aged ; Dyspnea/diagnosis ; Dyspnea/etiology ; Exercise Test ; Exercise Tolerance ; Female ; Forced Expiratory Volume ; Humans ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/complications ; Severity of Illness Index
    Language English
    Publishing date 2022-06-28
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2077867-3
    ISSN 1878-1519 ; 1569-9048
    ISSN (online) 1878-1519
    ISSN 1569-9048
    DOI 10.1016/j.resp.2022.103941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Optimising the Dyspnoea Challenge: exertional dyspnoea responses to changing treadmill gradients.

    Aitken, Craig R / Walsh, James R / Sabapathy, Surendran / Adams, Lewis / Morris, Norman R / Stewart, Glenn M

    Respiratory physiology & neurobiology

    2022  Volume 302, Page(s) 103915

    Abstract: Background: The Dyspnoea Challenge is a two-minute treadmill walk designed to measure exertional dyspnoea(ED). To efficiently individualise workload, we aimed to assess; 1) whether the Dyspnoea Challenge is responsive to 1% changes in treadmill gradient ...

    Abstract Background: The Dyspnoea Challenge is a two-minute treadmill walk designed to measure exertional dyspnoea(ED). To efficiently individualise workload, we aimed to assess; 1) whether the Dyspnoea Challenge is responsive to 1% changes in treadmill gradient and 2) the minimum gradient variation necessary to generate a clinically meaningful change in ED (≥1 modified Borg scale).
    Methods: Thirty individuals with COPD(GOLD II-IV) (age: 69.2 ± 9.2 years; FEV
    Results: Higher treadmill gradients generated stronger intensities of ED (3%:2.6 ± 1.8; 4%:2.8 ± 2.2; 5%:3.2 ± 2.2; 6%:3.4 ± 2.2; 7%:3.7 ± 1.8; 8%:4.0 ± 2.1units). Statistical changes were observed in ED(e.g.,3 vs. 5%: P = .03) and the MDP discomfort data(e.g.,4 vs. 6%: P = .04) at ≥ a 2% variation in treadmill gradient. Linear regression found a 4% variation in treadmill gradient corresponded to a rise in ED ≥ 1unit. Increases in ED intensity corresponded to heightened sensations of work/effort(P < .01) and breathing frequency(P < .01). There were no changes in emotional constructs(P = .27). While there was an increase in HR with increasing gradient(P < .01), no differences were observed in end-exercise S
    Conclusion: To significantly change ED, the treadmill gradient must be manipulated by ≥ 2%, with a ≥ 4% change in gradient required to induce a clinically meaningful change in ED.
    MeSH term(s) Aged ; Dyspnea ; Exercise Test/methods ; Exercise Tolerance/physiology ; Fatigue ; Humans ; Middle Aged ; Respiratory Function Tests
    Language English
    Publishing date 2022-04-29
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2077867-3
    ISSN 1878-1519 ; 1569-9048
    ISSN (online) 1878-1519
    ISSN 1569-9048
    DOI 10.1016/j.resp.2022.103915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Vascular access device type for systemic anti-cancer therapies: a scoping review protocol.

    Duggan, Caitriona / Hernon, Orlaith / Dunne, Rosie / McInerney, Veronica / Walsh, Stewart R / Carr, Peter J

    British journal of nursing (Mark Allen Publishing)

    2023  Volume 32, Issue 7, Page(s) S18–S22

    Abstract: Introduction: Vascular access devices (VADs) are the most common invasive procedure performed in acute medicine and cancer patients undergo multiple invasive vascular access procedures. Our aim is to identify the type of evidence available regarding the ...

    Abstract Introduction: Vascular access devices (VADs) are the most common invasive procedure performed in acute medicine and cancer patients undergo multiple invasive vascular access procedures. Our aim is to identify the type of evidence available regarding the best choice of VAD for cancer patients undergoing systemic anti-cancer therapy (SACT). In this article, the authors frame the scoping review protocol used, which will systematically report all published and unpublished literature around the use of VADs for the infusion of SACT in oncology.
    Inclusion criteria: For studies to be included, they must focus on people or populations aged 18 years or older and report on vascular access in cancer patients. The concept is the variety of VAD use in cancer and reported insertion and post-insertion complications. The context surrounds the intravenous treatment of SACT whether in a cancer centre or non-cancer setting.
    Methods: The JBI scoping review methodology framework will guide the conduct of this scoping review. Electronic databases (CINAHL, Cochrane, Medline and Embase) will be searched. Grey literature sources and the reference lists of key studies will be reviewed to identify those appropriate for inclusion. No date limits will be used in the searches and studies will be limited to the English language. Two reviewers will independently screen all titles and abstracts and full-text studies for inclusion, and a third reviewer will arbitrate disagreements. All bibliographic data, study characteristics and indicators will be collected and charted using a data extraction tool.
    MeSH term(s) Humans ; Neoplasms/drug therapy ; Research Design ; Review Literature as Topic
    Language English
    Publishing date 2023-04-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1119191-0
    ISSN 0966-0461
    ISSN 0966-0461
    DOI 10.12968/bjon.2023.32.7.S18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Assessment of oxygenation after balloon pulmonary angioplasty for patients with inoperable chronic thromboembolic pulmonary hypertension.

    Aitken, Craig R / Stewart, Glenn / Walsh, James / Seale, Helen / Morris, Norman R

    International journal of cardiology

    2021  Volume 337, Page(s) 104

    MeSH term(s) Angioplasty, Balloon ; Humans ; Hypertension, Pulmonary/diagnostic imaging ; Hypertension, Pulmonary/therapy ; Pulmonary Artery/diagnostic imaging ; Respiratory Physiological Phenomena
    Language English
    Publishing date 2021-05-15
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2021.05.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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