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  1. Book ; Online ; E-Book: Berne & Levy physiology

    Berne, Robert M. / Stanton, Bruce A / Koeppen, Bruce M. / Swiatecka-Urban, Agnieszka / Hall, Julianne M.

    2023  

    Author's details Bruce M. Koeppen [and others]
    Keywords Human physiology
    Subject code 612
    Language English
    Size 1 online resource (1308 pages)
    Edition 8th ed.
    Publisher Elsevier
    Publishing place Philadelphia, PA
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-84792-7 ; 978-0-323-84792-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Book: Financial structure of New York agricultural cooperatives / Bruce L. Anderson, Bernard F. Stanton

    Anderson, Bruce L / Stanton, B. F

    (A.E. res ; 79-19)

    1979  

    Institution New York State College of Agriculture and Life Sciences. / Dept. of Agricultural Economics
    Series title A.E. res ; 79-19
    Keywords Agriculture, Cooperative/Finance. ; Agriculture/Economic aspects
    Language English
    Size 18 p. :, ill. ;, 28 cm.
    Publisher Dept. of Agricultural Economics, Cornell University Agricultural Experiment Station, New York State College of Agriculture and Life Sciences
    Publishing place Ithaca, N.Y
    Document type Book
    Note Cover title. ; "September 1979."
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Extracellular Vesicles and Host-Pathogen Interactions: A Review of Inter-Kingdom Signaling by Small Noncoding RNA.

    Stanton, Bruce A

    Genes

    2021  Volume 12, Issue 7

    Abstract: The focus of this brief review is to describe the role of noncoding regulatory RNAs, including short RNAs (sRNA), transfer RNA (tRNA) fragments and microRNAs (miRNA) secreted in extracellular vesicles (EVs), in inter-kingdom communication between ... ...

    Abstract The focus of this brief review is to describe the role of noncoding regulatory RNAs, including short RNAs (sRNA), transfer RNA (tRNA) fragments and microRNAs (miRNA) secreted in extracellular vesicles (EVs), in inter-kingdom communication between bacteria and mammalian (human) host cells. Bacteria secrete vesicles that contain noncoding regulatory RNAs, and recent studies have shown that the bacterial vesicles fuse with and deliver regulatory RNAs to host cells, and similar to eukaryotic miRNAs, regulatory RNAs modulate the host immune response to infection. Recent studies have also demonstrated that mammalian cells secrete EVs containing miRNAs that regulate the gut microbiome, biofilm formation and the bacterial response to antibiotics. Thus, as evidence accumulates it is becoming clear that the secretion of noncoding regulatory RNAs and miRNAs in extracellular vesicles is an important mechanism of bidirectional communication between bacteria and mammalian (human) host cells. However, additional research is necessary to elucidate how noncoding regulatory RNAs and miRNA secreted in extracellular vesicles mediate inter-kingdom communication.
    MeSH term(s) Animals ; Extracellular Vesicles/genetics ; Extracellular Vesicles/pathology ; Host-Pathogen Interactions ; Humans ; MicroRNAs/genetics ; RNA, Small Untranslated/genetics ; Signal Transduction
    Chemical Substances MicroRNAs ; RNA, Small Untranslated
    Language English
    Publishing date 2021-06-30
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes12071010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells.

    Lau, Fung Yi / Chui, Chung Hin / Gambari, Roberto / Kok, Stanton Hon Lung / Kan, Kin Luen / Cheng, Gregory Yin Ming / Wong, Raymond Siu Ming / Teo, Ivy Tuang Ngo / Cheng, Chor Hing / Wan, Thomas Shek Kwong / Chan, Albert Sun Chi / Tang, Johnny Cheuk On

    International journal of molecular medicine

    2005  Volume 16, Issue 6, Page(s) 1157–1162

    Abstract: ... Here, we further report the potential anti-cancer activity of the warmed water extract of Brucea ...

    Abstract We have recently demonstrated the antiproliferative and apoptotic activities of herbal traditional Chinese medicines, including the analomous fruit extract of Gleditsia sinensis, the fresh juice of Scutellaria barbata and the warmed water extract of Radix Sophorae Tonkinensis on a series of human carcinoma cells. Here, we further report the potential anti-cancer activity of the warmed water extract of Brucea javanica (BJE). Four cancer cell lines, including A549 non-small cell lung cancer, Hep3B hepatocellular carcinoma, MDA-MB231 breast cancer and SLMT-1 oesophageal squamous cell carcinoma, were incubated with BJE and strong apoptotic induction was observed under inverted microscopic investigation for all of the four cell lines tested. Using the MDA-MB231 breast cancer cell line as an experimental model, additional analyses supported the hypothesis that the mitochondrial membrane potential depolarization pathway was induced by BJE. The APO-1/Fas receptor death induction pathway was not activated under the influence of BJE, as studied by staining with Fas ligand and Fas receptor specific antibodies. Accordingly, only weak activation of caspase 8 was observed upon BJE treatment. On the other hand, caspase 3 activity was stimulated up to five-fold in BJE-treated cells compared to untreated controls. Oligonucleosomal DNA fragmentation formation was detected by labelling the nucleic acid ladders with TdT-mediated dUTP nick end labelling. Collectively, BJE-induced cancer cell death proceeds through a mitochondrial dependent pathway associated with caspase 3 activation.
    MeSH term(s) Apoptosis/drug effects ; Bone Marrow/drug effects ; Brucea/chemistry ; Caspase 3 ; Caspase 8 ; Caspases/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; DNA Fragmentation/drug effects ; Humans ; Membrane Potentials/drug effects ; Neoplasms/drug therapy ; Neoplasms/pathology ; Phytotherapy ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; fas Receptor/metabolism
    Chemical Substances Plant Extracts ; fas Receptor ; CASP3 protein, human (EC 3.4.22.-) ; CASP8 protein, human (EC 3.4.22.-) ; Caspase 3 (EC 3.4.22.-) ; Caspase 8 (EC 3.4.22.-) ; Caspases (EC 3.4.22.-)
    Language English
    Publishing date 2005-12
    Publishing country Greece
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1444428-8
    ISSN 1107-3756
    ISSN 1107-3756
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4942: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Berne & Levy physiology

    Koeppen, Bruce M. / Stanton, Bruce A. / Berne, Robert M.

    (A student consult title)

    2010  

    Title variant Physiology
    Author's details ed. Bruce M. Koeppen ; Bruce A. Stanton
    Series title A student consult title
    Keywords Physiological Phenomena
    Language English
    Size XII, 836 S. : Ill., graph. Darst.
    Edition 6. ed., updated ed.
    Publisher Mosby Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    Note Previous ed.: 2004
    Accompanying material Zugang zu Internetausgabe über Code
    Old title Frühere Auflage u.d.T. Physiology
    HBZ-ID HT016361904
    ISBN 978-0-323-07362-2 ; 0-323-07362-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 2560 order for loan Magazin
    Zugang zur Internetausgabe aus lizenzrechtlichen Gründen nicht verfügbar

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Extracellular Vesicles and Host–Pathogen Interactions: A Review of Inter-Kingdom Signaling by Small Noncoding RNA

    Stanton, Bruce A.

    Genes. 2021 June 30, v. 12, no. 7

    2021  

    Abstract: The focus of this brief review is to describe the role of noncoding regulatory RNAs, including short RNAs (sRNA), transfer RNA (tRNA) fragments and microRNAs (miRNA) secreted in extracellular vesicles (EVs), in inter-kingdom communication between ... ...

    Abstract The focus of this brief review is to describe the role of noncoding regulatory RNAs, including short RNAs (sRNA), transfer RNA (tRNA) fragments and microRNAs (miRNA) secreted in extracellular vesicles (EVs), in inter-kingdom communication between bacteria and mammalian (human) host cells. Bacteria secrete vesicles that contain noncoding regulatory RNAs, and recent studies have shown that the bacterial vesicles fuse with and deliver regulatory RNAs to host cells, and similar to eukaryotic miRNAs, regulatory RNAs modulate the host immune response to infection. Recent studies have also demonstrated that mammalian cells secrete EVs containing miRNAs that regulate the gut microbiome, biofilm formation and the bacterial response to antibiotics. Thus, as evidence accumulates it is becoming clear that the secretion of noncoding regulatory RNAs and miRNAs in extracellular vesicles is an important mechanism of bidirectional communication between bacteria and mammalian (human) host cells. However, additional research is necessary to elucidate how noncoding regulatory RNAs and miRNA secreted in extracellular vesicles mediate inter-kingdom communication.
    Keywords biofilm ; humans ; immune response ; intestinal microorganisms ; microRNA ; non-coding RNA ; secretion ; transfer RNA
    Language English
    Dates of publication 2021-0630
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2527218-4
    ISSN 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes12071010
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Transfer RNA-Derived Fragments, the Underappreciated Regulatory Small RNAs in Microbial Pathogenesis.

    Li, Zhongyou / Stanton, Bruce A

    Frontiers in microbiology

    2021  Volume 12, Page(s) 687632

    Abstract: In eukaryotic organisms, transfer RNA (tRNA)-derived fragments have diverse biological functions. Considering the conserved sequences of tRNAs, it is not surprising that endogenous tRNA fragments in bacteria also play important regulatory roles. Recent ... ...

    Abstract In eukaryotic organisms, transfer RNA (tRNA)-derived fragments have diverse biological functions. Considering the conserved sequences of tRNAs, it is not surprising that endogenous tRNA fragments in bacteria also play important regulatory roles. Recent studies have shown that microbes secrete extracellular vesicles (EVs) containing tRNA fragments and that the EVs deliver tRNA fragments to eukaryotic hosts where they regulate gene expression. Here, we review the literature describing microbial tRNA fragment biogenesis and how the fragments secreted in microbial EVs suppress the host immune response, thereby facilitating chronic infection. Also, we discuss knowledge gaps and research challenges for understanding the pathogenic roles of microbial tRNA fragments in regulating the host response to infection.
    Language English
    Publishing date 2021-05-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.687632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of

    Stanton, Bruce A

    American journal of physiology. Cell physiology

    2017  Volume 312, Issue 4, Page(s) C357–C366

    Abstract: In the healthy lung the opportunistic pathogen, ...

    Abstract In the healthy lung the opportunistic pathogen,
    MeSH term(s) Chlorine/immunology ; Cystic Fibrosis Transmembrane Conductance Regulator/immunology ; Humans ; Immunity, Mucosal/immunology ; Ion Channel Gating/immunology ; Models, Immunological ; Mucociliary Clearance/immunology ; Pneumonia, Bacterial/immunology ; Pneumonia, Bacterial/microbiology ; Pseudomonas Infections/immunology ; Pseudomonas Infections/microbiology ; Pseudomonas aeruginosa/immunology ; Respiratory Mucosa/immunology
    Chemical Substances CFTR protein, human ; Cystic Fibrosis Transmembrane Conductance Regulator (126880-72-6) ; Chlorine (4R7X1O2820)
    Language English
    Publishing date 2017-01-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00373.2016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.89: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Extracellular vesicles secreted by primary human bronchial epithelial cells reduce

    Sarkar, Sharanya / Barnaby, Roxanna / Nymon, Amanda B / Taatjes, Douglas J / Kelley, Thomas J / Stanton, Bruce A

    American journal of physiology. Lung cellular and molecular physiology

    2023  Volume 326, Issue 2, Page(s) L164–L174

    Abstract: Cystic fibrosis (CF) results in a reduction in the volume of airway surface liquid, increased accumulation of viscous mucus, persistent antibiotic-resistant lung infections that cause chronic inflammation, and a decline in lung function. More than 50% of ...

    Abstract Cystic fibrosis (CF) results in a reduction in the volume of airway surface liquid, increased accumulation of viscous mucus, persistent antibiotic-resistant lung infections that cause chronic inflammation, and a decline in lung function. More than 50% of adults with CF are chronically colonized by
    MeSH term(s) Adult ; Humans ; Mice ; Animals ; Cystic Fibrosis/metabolism ; Pseudomonas aeruginosa/physiology ; Pseudomonas Infections ; Lung ; Inflammation/metabolism ; Disease Models, Animal ; Epithelial Cells ; Extracellular Vesicles/metabolism
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1013184-x
    ISSN 1522-1504 ; 1040-0605
    ISSN (online) 1522-1504
    ISSN 1040-0605
    DOI 10.1152/ajplung.00253.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.89: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.A 2749: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Book: Berne & Levy physiology

    Koeppen, Bruce M / Stanton, Bruce A

    2018  

    Title variant Berne and Levy physiology ; Physiology
    Author's details editors, Bruce M. Koeppen, Bruce A. Stanton
    MeSH term(s) Physiological Phenomena
    Language English
    Size p. ;, cm.
    Edition Seventh edition.
    Document type Book
    Note Includes index.
    ISBN 9780323393942 ; 9780323443388 ; 0323393942 ; 0323443389
    Database Catalogue of the US National Library of Medicine (NLM)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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