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Article: The role of PET/CT imaging in penile cancer.

Ottenhof, Sarah R / Vegt, Erik

2017 Volume 6, Issue 5, Page(s) 833–838

Abstract: Positron emission tomography (PET) imaging ... ...

Abstract	Positron emission tomography (PET) imaging with
Language	English
Publishing date	2017-11-08
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2851630-8
ISSN	2223-4691 ; 2223-4691 ; 2223-4683
ISSN (online)	2223-4691
ISSN	2223-4691 ; 2223-4683
DOI	10.21037/tau.2017.04.36
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Article: Reduction of [

Cox, Christina P W / Brabander, Tessa / Vegt, Erik / de Lussanet de la Sablonière, Quido G / Graven, Laura H / Verburg, Frederik A / Segbers, Marcel

EJNMMI physics

2024 Volume 11, Issue 1, Page(s) 27

Abstract: Background: New digital detectors and block-sequential regularized expectation maximization (BSREM) reconstruction algorithm improve positron emission tomography (PET)/magnetic resonance (MR) image quality. The impact on image quality may differ from ... ...

Abstract	Background: New digital detectors and block-sequential regularized expectation maximization (BSREM) reconstruction algorithm improve positron emission tomography (PET)/magnetic resonance (MR) image quality. The impact on image quality may differ from analogue PET/computed tomography (CT) protocol. The aim of this study is to determine the potential reduction of injected [ Methods: NEMA IQ phantom data and 25 patients scheduled for a diagnostic PET/MR were included. According to our current protocol, 1.5 MBq [ Results: Phantom analysis resulted in a possible injected activity reduction of 50% with factor β = 600. Quantitative analysis of patient images revealed a possible injected activity reduction of 67% with factor β = 600. Both with equal or improved image quality as compared to PET/CT. However, based on visual scoring a maximum activity reduction of 33% with factor β = 450 was acceptable, which was further limited by lesion detectability analysis to an injected activity reduction of 17% with factor β = 450. Conclusion: A digital [
Language	English
Publishing date	2024-03-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2768912-8
ISSN	2197-7364
ISSN	2197-7364
DOI	10.1186/s40658-024-00629-z
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Article ; Online: Factors influencing brown fat activation in FDG PET/CT: a retrospective analysis of 15,000+ cases.

Steinberg, Jeffrey D / Vogel, Wouter / Vegt, Erik

The British journal of radiology

2017 Volume 90, Issue 1075, Page(s) 20170093

Abstract: Objective: Brown fat can exhibit high uptake of fluorine-18 fludeoxyglucose (: Methods: A retrospective study of : Results: The total reported BAT activation was 3.6%. BAT activation was reported significantly more often in patients who were ... ...

Abstract	Objective: Brown fat can exhibit high uptake of fluorine-18 fludeoxyglucose ( Methods: A retrospective study of Results: The total reported BAT activation was 3.6%. BAT activation was reported significantly more often in patients who were female (p < 0.0001), younger (p < 0.0001), with lower body mass index (p < 0.0001), with lower blood glucose levels (p = 0.01), indicated for breast cancer (p = 0.004), not administered chemotherapy recently before the scan (p < 0.0001) and shown to have BAT activation in a previous scan (p < 0.0001). BAT activation was also reported significantly more for lower outdoor temperatures (p < 0.0001) and for late morning scans than for afternoon (p = 0.005) and early morning (p = 0.001) scans. Conclusion: This retrospective study of 15,109 scans highlights multiple factors contributing to BAT activation on
MeSH term(s)	Adipose Tissue, Brown/diagnostic imaging ; Adipose Tissue, Brown/metabolism ; Adult ; Aged ; Aged, 80 and over ; Female ; Fluorodeoxyglucose F18/pharmacokinetics ; Humans ; Male ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Radiopharmaceuticals/pharmacokinetics ; Retrospective Studies ; Young Adult
Chemical Substances	Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2017-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr.20170093
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Article ; Online: Staging

Voskuilen, Charlotte S / van Gennep, Erik J / Einerhand, Sarah M H / Vegt, Erik / Donswijk, Maarten L / Bruining, Annemarie / van der Poel, Henk G / Horenblas, Simon / Hendricksen, Kees / van Rhijn, Bas W G / Mertens, Laura S

European urology oncology

2021 Volume 5, Issue 3, Page(s) 366–369

Abstract: Given the high risk of systemic relapse following initial therapy for muscle-invasive bladder cancer (MIBC), improved pretreatment staging is needed. We evaluated the incremental value ... ...

Abstract	Given the high risk of systemic relapse following initial therapy for muscle-invasive bladder cancer (MIBC), improved pretreatment staging is needed. We evaluated the incremental value of
MeSH term(s)	Fluorodeoxyglucose F18 ; Humans ; Lymphatic Metastasis ; Neoplasm Recurrence, Local ; Positron Emission Tomography Computed Tomography/methods ; Retrospective Studies ; Urinary Bladder Neoplasms/diagnostic imaging ; Urinary Bladder Neoplasms/therapy
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2021-02-11
Publishing country	Netherlands
Document type	Journal Article
ISSN	2588-9311
ISSN (online)	2588-9311
DOI	10.1016/j.euo.2021.01.005
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Article ; Online: Progressive Visual Occlusion and Postural Control Responses in Individuals With and Without Chronic Ankle Instability.

VanDeMark, Lilly H / Vander Vegt, Christina B / Ford, Cassie B / Mihalik, Jason P / Wikstrom, Erik A

Journal of sport rehabilitation

2021 Volume 30, Issue 8, Page(s) 1115–1120

Abstract: Context: Prophylactic and rehabilitative balance training is needed to maximize postural control and develop appropriate sensory organization strategies. Partially occluding vision during functional exercise may promote appropriate sensory organization ... ...

Abstract	Context: Prophylactic and rehabilitative balance training is needed to maximize postural control and develop appropriate sensory organization strategies. Partially occluding vision during functional exercise may promote appropriate sensory organization strategies, but little is known about the influence of partially occluded vision on postural control in those with and without a history of musculoskeletal injury. Objective: To determine the effect of increasing levels of visual occlusion on postural control in a heterogeneous sample of those with and without chronic ankle instability (CAI). The secondary objective was to explore postural control responses to increasing levels of visual occlusion among those with unilateral and bilateral CAI relative to uninjured controls. Design: Cross-sectional. Setting: Sports medicine research laboratory. Patients or other participants: Twenty-five participants with unilateral CAI, 10 with bilateral CAI, and 16 participants with no history of lower extremity injury. Main outcome measures: All participants completed four 3-minute postural control assessments in double-limb stance under the following 4 visual conditions: (1) eyes open, (2) low occlusion, (3) high occlusion, and (4) eyes closed. Low- and high-occlusion conditions were produced using stroboscopic eyewear. Postural control outcomes included time-to-boundary minima means in the anteroposterior (TTB-AP) and mediolateral directions (TTB-ML). Repeated-measures analysis of variances tested the effects of visual condition on TTB-AP and TTB-ML. Results: Postural control under the eyes-open condition was significantly better (ie, higher) than the limited visual occlusion and eyes-closed conditions (P < .001) for TTB-AP and TTB-ML. For TTB-AP only, partially occluded vision resulted in better postural control than the eyes-closed condition (P ≤ .003). Conclusions: Partial and complete visual occlusion impaired postural control during dual-limb stance in a heterogeneous sample of those with and without CAI. Stroboscopic eyewear appears to induce postural control impairments to the same extent as complete visual occlusion in the mediolateral direction.
MeSH term(s)	Ankle ; Ankle Joint ; Cross-Sectional Studies ; Humans ; Joint Instability ; Postural Balance
Language	English
Publishing date	2021-06-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	1106769-x
ISSN	1543-3072 ; 1056-6716
ISSN (online)	1543-3072
ISSN	1056-6716
DOI	10.1123/jsr.2020-0466
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Article ; Online: Recent developments in penile cancer imaging.

de Vries, Hielke M / Brouwer, Oscar R / Heijmink, Stijn / Horenblas, Simon / Vegt, Erik

Current opinion in urology

2019 Volume 29, Issue 2, Page(s) 150–155

Abstract: Purpose of review: This review discusses new findings in penile cancer imaging in relation to the European Association of Urology and National Comprehensive Cancer Network guidelines.: Recent findings: For imaging in penile cancer patients who are ... ...

Abstract	Purpose of review: This review discusses new findings in penile cancer imaging in relation to the European Association of Urology and National Comprehensive Cancer Network guidelines. Recent findings: For imaging in penile cancer patients who are candidates for organ-sparing primary treatment, ultrasound with Doppler seems to be the method of choice in addition to physical examination. The sentinel node biopsy (SNB) procedure is used to detect small nodal metastases in clinically node-negative patients. In recent years, this procedure has been enhanced by 3D imaging using single photon emission computed tomography (SPECT) with computed tomography (CT) to improve preoperative localization and interpretation of sentinel nodes, as well as hybrid fluorescent and radioactive tracers to increase intraoperative localization of sentinel nodes. 18F-fluorodeoxyglucose PET (FDG-PET) with CT appears to be mainly useful for pelvic and distant staging in clinically node-positive patients. Other modalities with a potential future role in penile cancer are ultrasound with shear wave elastography, FDG-PET with MRI and ultrasmall paramagnetic iron oxide-enhanced MRI. Summary: Imaging modalities in penile cancer have advanced throughout the years, assisting in treatment decision-making and during invasive procedures.
MeSH term(s)	Fluorodeoxyglucose F18 ; Humans ; Lymph Nodes ; Male ; Neoplasm Staging ; Penile Neoplasms/diagnostic imaging ; Positron-Emission Tomography ; Radiopharmaceuticals ; Sentinel Lymph Node ; Sentinel Lymph Node Biopsy
Chemical Substances	Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2019-01-02
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1091792-5
ISSN	1473-6586 ; 0963-0643
ISSN (online)	1473-6586
ISSN	0963-0643
DOI	10.1097/MOU.0000000000000585
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Article ; Online: Multimodal Therapy Versus Primary Surgery for Gastric and Gastroesophageal Junction Diffuse Type Carcinoma, with a Focus on Signet Ring Cell Carcinoma: A Nationwide Study.

Gertsen, Emma C / van der Veen, Arjen / Brenkman, Hylke J F / Brosens, Lodewijk A A / van der Post, Rachel S / Verhoeven, Rob H A / Luijten, Josianne C H B M / Vissers, Pauline A J / Vegt, Erik / van Hillegersberg, Richard / Siersema, Peter D / Ruurda, Jelle P

Annals of surgical oncology

2023 Volume 31, Issue 3, Page(s) 1760–1772

Abstract: Background: Diffuse type adenocarcinoma and, more specifically, signet ring cell carcinoma (SRCC) of the stomach and gastroesophageal junction (GEJ) have a poor prognosis and the value of neoadjuvant chemo(radio)therapy (nCRT) is unclear.: Methods: ... ...

Abstract	Background: Diffuse type adenocarcinoma and, more specifically, signet ring cell carcinoma (SRCC) of the stomach and gastroesophageal junction (GEJ) have a poor prognosis and the value of neoadjuvant chemo(radio)therapy (nCRT) is unclear. Methods: All patients who underwent surgery for diffuse type gastric and GEJ carcinoma between 2004 and 2015 were retrospectively included from the Netherlands Cancer Registry. The primary outcome was overall survival after surgery. Kaplan-Meier curves were plotted. Furthermore, multivariable Poisson and Cox regressions were performed, correcting for confounders. To comply with the Cox regression proportional hazard assumption, gastric cancer survival was split into two groups, i.e. <90 days and >90 days, postoperatively by adding an interaction variable. Results: Analyses included 2046 patients with diffuse type cancer: 1728 gastric cancers (50% SRCC) and 318 GEJ cancers (39% SRCC). In the gastric cancer group, 49% received neoadjuvant chemotherapy (nCT) and 51% received primary surgery (PS). All-cause mortality within 90 days postoperatively was lower after nCT (hazard ratio [HR] 0.29, 95% confidence interval [CI] 0.20-0.44; p < 0.001). Also after 90 days, mortality was lower in the nCT group (HR for the interaction variable 2.84, 95% CI 1.87-4.30, p < 0.001; total HR 0.292.84 = 0.84). In the GEJ group, 38% received nCT, 22% received nCRT, and 39% received PS. All-cause mortality was lower after nCT (HR 0.63, 95% CI 0.43-0.93; p = 0.020) compared with PS. The nCRT group was removed from the Cox regression analysis since the Kaplan-Meier curves of nCRT and PS intersected. The results for gastric and GEJ carcinomas were similar between the SRCC and non-SRCC subgroups. Conclusion:* For gastric and GEJ diffuse type cancer, including SRCC, nCT was associated with increased survival.
MeSH term(s)	Humans ; Stomach Neoplasms/pathology ; Retrospective Studies ; Neoplasm Staging ; Adenocarcinoma/surgery ; Carcinoma, Signet Ring Cell/pathology ; Esophagogastric Junction/pathology
Language	English
Publishing date	2023-12-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-023-14690-y
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Article ; Online: Safety and Efficacy of

Reinders, Margot T M / van Erpecum, Karel J / Smits, Maarten L J / Braat, Arthur J A T / Bruijne, Joep de / Bruijnen, Rutger / Sprengers, Dave / Man, Robert A de / Vegt, Erik / IJzermans, Jan N M / Moelker, Adriaan / Lam, Marnix G E H

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

2022 Volume 63, Issue 12, Page(s) 1891–1898

Abstract: The safety and efficacy ... ...

Abstract	The safety and efficacy of
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/pathology ; Prospective Studies ; Quality of Life ; Ascites/etiology ; Ascites/therapy ; Embolization, Therapeutic/adverse effects ; Microspheres ; Treatment Outcome ; Yttrium Radioisotopes
Chemical Substances	Yttrium Radioisotopes
Language	English
Publishing date	2022-05-19
Publishing country	United States
Document type	Clinical Trial, Phase II ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80272-4
ISSN	1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
ISSN (online)	1535-5667
ISSN	0097-9058 ; 0161-5505 ; 0022-3123
DOI	10.2967/jnumed.122.263823
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Article: Correlation between Histopathological Prognostic Tumor Characteristics and [

Boers, Jorianne / Eisses, Bertha / Zwager, Mieke C / van Geel, Jasper J L / Bensch, Frederike / de Vries, Erik F J / Hospers, Geke A P / Glaudemans, Andor W J M / Brouwers, Adrienne H / den Dekker, Martijn A M / Elias, Sjoerd G / Kuip, Evelien J M / van Herpen, Carla M L / Jager, Agnes / van der Veldt, Astrid A M / Oprea-Lager, Daniela E / de Vries, Elisabeth G E / van der Vegt, Bert / Menke-van der Houven van Oordt, Willemien C /

Schröder, Carolina P

Diagnostics (Basel, Switzerland)

2024 Volume 14, Issue 4

Abstract: Background: In metastatic breast cancer (MBC), [: Patients and methods: Patients with non-rapidly progressive MBC of all subtypes prospectively underwent a baseline histological metastasis biopsy and [: Results: Of 200 patients, 188 had evaluable ... ...

Abstract	Background: In metastatic breast cancer (MBC), [ Patients and methods: Patients with non-rapidly progressive MBC of all subtypes prospectively underwent a baseline histological metastasis biopsy and [ Results: Of 200 patients, 188 had evaluable metastasis biopsies, and 182 of these contained tumor. HER2 positivity and Ki-67 ≥ 20% were correlated with higher [ Conclusions: [
Language	English
Publishing date	2024-02-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics14040416
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Article: Prognostic Value of [

Pullen, Lieke C E / Noortman, Wyanne A / Triemstra, Lianne / de Jongh, Cas / Rademaker, Fenna J / Spijkerman, Romy / Kalisvaart, Gijsbert M / Gertsen, Emma C / de Geus-Oei, Lioe-Fee / Tolboom, Nelleke / de Steur, Wobbe O / Dantuma, Maura / Slart, Riemer H J A / van Hillegersberg, Richard / Siersema, Peter D / Ruurda, Jelle P / van Velden, Floris H P / Vegt, Erik / On Behalf Of The Plastic Study Group

Cancers

2023 Volume 15, Issue 11

Abstract: Aim: To improve identification of peritoneal and distant metastases in locally advanced gastric cancer using [: Methods: [: Results: None of the models could identify metastases with low AUCs of 0.59, 0.51, and 0.56, for the clinical, radiomic, ... ...

Abstract	Aim: To improve identification of peritoneal and distant metastases in locally advanced gastric cancer using [ Methods: [ Results: None of the models could identify metastases with low AUCs of 0.59, 0.51, and 0.56, for the clinical, radiomic, and clinicoradiomic model, respectively. Subgroup analysis of intestinal and mixed-type tumours resulted in low AUCs of 0.67 and 0.60 for the clinical and radiomic models, and a moderate AUC of 0.71 in the clinicoradiomic model. Subgroup analysis of diffuse-type tumours did not improve the classification performance. Conclusion: Overall, [
Language	English
Publishing date	2023-05-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15112874
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