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  1. Article: Mayo Clinic office visit. Drug-eluting stents. An interview with Abhiram Prasad, M.D.

    Prasad, Abhiram

    Mayo Clinic women's healthsource

    2007  Volume 11, Issue 5, Page(s) 6

    MeSH term(s) Drug Implants/adverse effects ; Humans ; Stents/adverse effects ; Thrombosis/prevention & control
    Chemical Substances Drug Implants
    Language English
    Publishing date 2007-05
    Publishing country United States
    Document type Interview
    ZDB-ID 2192476-4
    ISSN 1091-0220
    ISSN 1091-0220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6141: Show issues Location:
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  2. Article: Nonatheromatous Coronary Kink Causing Angiographic Obstruction: A Rare Structural Anomaly.

    Jhawar, Nikita / Prasad, Abhiram / Gharacholou, S Michael

    Case reports in cardiology

    2023  Volume 2023, Page(s) 6626263

    Abstract: Ischemic symptoms may be explained by a multitude of coronary pathologies, including coronary artery tortuosity, atherosclerosis, fibromuscular dysplasia, vasculitis, coronary vasospasm, or microvascular disease. We present an unusual case of coronary ... ...

    Abstract Ischemic symptoms may be explained by a multitude of coronary pathologies, including coronary artery tortuosity, atherosclerosis, fibromuscular dysplasia, vasculitis, coronary vasospasm, or microvascular disease. We present an unusual case of coronary kinking in a patient presenting with exertional jaw pain in the absence of atherosclerotic risk factors. Multimodality imaging, coronary imaging, and coronary physiology helped establish the diagnosis and guide management.
    Language English
    Publishing date 2023-08-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627627-6
    ISSN 2090-6412 ; 2090-6404
    ISSN (online) 2090-6412
    ISSN 2090-6404
    DOI 10.1155/2023/6626263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: What is Takotsubo (Stress) Cardiomyopathy?

    Prasad, Abhiram

    European cardiology

    2018  Volume 10, Issue 1, Page(s) 6–8

    Abstract: Takotsubo/stress cardiomyopathy (TC) or apical ballooning syndrome is an increasingly recognised entity around the world. It is an acute reversible cardiac syndrome that has a striking female predominance, with approximately 90 % of cases occurring in ... ...

    Abstract Takotsubo/stress cardiomyopathy (TC) or apical ballooning syndrome is an increasingly recognised entity around the world. It is an acute reversible cardiac syndrome that has a striking female predominance, with approximately 90 % of cases occurring in women, the vast majority of whom are post-menopausal. Chest pain and dysponea are the most common presenting symptoms. The symptoms and signs are similar to those in other acute cardiac conditions characterised by acute myocardial ischemia or heart failure. A characteristic feature of the syndrome is its relationship to emotional or physical stressful triggers. The process of diagnosing TC is, to a large extent, one of exclusion of other conditions that it mimics. The Mayo Clinic diagnostic criteria are the most widely used. Since acute coronary syndrome is often suspected before the diagnosis of TC is made, initial treatment is often similar to that for an acute myocardial infarction. However, after the diagnosis of TC is confirmed, treatment is supportive with monitoring and treatment of complications. The vast majority of patients with TC have good prognosis with complete resolution of systolic dysfunction.
    Language English
    Publishing date 2018-09-17
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1758-3764
    ISSN (online) 1758-3764
    DOI 10.15420/ecr.2015.10.01.6
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  4. Article ; Online: Augmented Reality and Ultrasound-Guided Vascular Access.

    Al-Abcha, Abdullah / Alkhouli, Mohamad / Prasad, Abhiram / Bell, Malcolm / Yalamuri, Suraj / Lerman, Amir / Gulati, Rajiv / Simard, Trevor

    Circulation. Cardiovascular interventions

    2023  Volume 16, Issue 9, Page(s) e013360

    MeSH term(s) Humans ; Augmented Reality ; Treatment Outcome ; Ultrasonography, Interventional
    Language English
    Publishing date 2023-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2450797-0
    ISSN 1941-7632 ; 1941-7640
    ISSN (online) 1941-7632
    ISSN 1941-7640
    DOI 10.1161/CIRCINTERVENTIONS.123.013360
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    Zs.A 6746: Show issues Location:
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  5. Article ; Online: MY APPROACH to Takotsubo (stress) cardiomyopathy.

    Prasad, Abhiram

    Trends in cardiovascular medicine

    2015  Volume 25, Issue 8, Page(s) 751–752

    MeSH term(s) Age Factors ; Aged ; Catecholamines/metabolism ; Chest Pain/diagnosis ; Chest Pain/etiology ; Diagnosis, Differential ; Echocardiography, Doppler/methods ; Electrocardiography/methods ; Female ; Humans ; Magnetic Resonance Imaging, Cine/methods ; Male ; Middle Aged ; Monitoring, Physiologic ; Multimodal Imaging/methods ; Myocardial Infarction/diagnosis ; Myocardial Infarction/therapy ; Practice Patterns, Physicians' ; Risk Assessment ; Sex Factors ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/therapy
    Chemical Substances Catecholamines
    Language English
    Publishing date 2015-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2015.05.015
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    Zs.A 3419: Show issues Location:
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  6. Article ; Online: Patients With Coronary Microvascular Dysfunction Have Less Circulating α-Klotho.

    Akhiyat, Nadia / Ozcan, Ilke / Gulati, Rajiv / Prasad, Abhiram / Tchkonia, Tamara / Kirkland, James L / Lewis, Bradley / Lerman, Lilach O / Lerman, Amir

    Journal of the American Heart Association

    2024  , Page(s) e031972

    Abstract: Background: Coronary microvascular dysfunction (CMD) represents an early functional characteristic of coronary vascular aging. Klotho (α-klotho) is a circulating protein inversely linked to physiological aging. We examined low klotho as a potential ... ...

    Abstract Background: Coronary microvascular dysfunction (CMD) represents an early functional characteristic of coronary vascular aging. Klotho (α-klotho) is a circulating protein inversely linked to physiological aging. We examined low klotho as a potential marker for vascular aging in patients with CMD and no coronary artery disease.
    Methods and results: Patients undergoing nonurgent angiogram for chest pain who had no coronary artery disease underwent invasive coronary microvascular and endothelial function testing. CMD was defined by ≤50% increase in coronary blood flow (percentage change in coronary blood flow) in response to intracoronary acetylcholine or coronary flow reserve ≤2. Fresh arterial whole blood was used to analyze circulating endothelial progenitor cells with flow cytometry. Stored arterial plasma was used for klotho analysis by ELISA. Participants with CMD (n=62) were compared with those without CMD (n=36). Those with CMD were age 55±10 years (versus 51±11 years;
    Conclusions: Klotho may be a biomarker for CMD and may be a therapeutic target for groups of patients without significant traditional cardiovascular risk.
    Language English
    Publishing date 2024-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.123.031972
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  7. Article ; Online: Slow but steady progress towards understanding peri-procedural myocardial infarction.

    Prasad, Abhiram

    European heart journal

    2013  Volume 34, Issue 22, Page(s) 1615–1617

    MeSH term(s) Female ; Humans ; Male ; Myocardial Infarction/etiology ; Percutaneous Coronary Intervention/adverse effects
    Language English
    Publishing date 2013-06
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/eht103
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    Zs.A 1563: Show issues Location:
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    Zs.MO 640: Show issues

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  8. Article ; Online: Acute coronary occlusion and percutaneous coronary intervention after out-of-hospital cardiac arrest.

    Lobo, Ronstan / Sarma, Dhruv / Tabi, Meir / Barsness, Gregory W / Prasad, Abhiram / Bell, Malcolm R / Jentzer, Jacob C

    The Journal of invasive cardiology

    2024  Volume 36, Issue 1

    Abstract: Objectives: Early coronary angiography (CAG) has been recommended in selected patients following out-of-hospital-cardiac-arrest (OHCA). We aimed to identify clinical features associated with acute coronary occlusion (ACO) and evaluate the associations ... ...

    Abstract Objectives: Early coronary angiography (CAG) has been recommended in selected patients following out-of-hospital-cardiac-arrest (OHCA). We aimed to identify clinical features associated with acute coronary occlusion (ACO) and evaluate the associations between ACO, successful percutaneous coronary intervention (PCI) and outcomes in this population.
    Methods: We included comatose OHCA patients treated with targeted temperature management (TTM) between December 2005 and September 2016 who underwent early CAG within 24 hours. The co-primary outcomes were all-cause 30-day mortality and good neurological outcome (modified Rankin Score [mRS] ≤2) at hospital discharge.
    Results: Among 155 patients (93% shockable arrest rhythm, 55% with ST elevation), 133 (86%) had coronary artery stenosis ≥50% and 65 (42%) had ACO. ST elevation (sensitivity 74%, specificity 59%, OR 4.0, 95% CI 2.0-8.1) and elevated first troponin (sensitivity 88%, specificity 26%, OR 2.5, 95% CI 1.1-6.1) had limited sensitivity and specificity for ACO. Unadjusted 30-day mortality did not differ significantly by coronary disease severity or ACO. Successful PCI was associated with a lower risk of 30-day mortality (adjusted HR 0.5, 95% CI 0.2-0.9, P=.03), especially among patients with ACO (adjusted HR 0.4, 95% CI 0.1-0.9, P=0.03). After adjustment, ACO and PCI were not associated with the probability of good neurological outcome.
    Conclusions: In this select cohort of resuscitated OHCA patients undergoing CAG, unstable coronary disease is highly prevalent and successful PCI was associated with a higher probability of 30-day survival, especially among those with ACO. Neither ACO nor successful PCI were independently associated with good neurological outcome.
    MeSH term(s) Humans ; Coronary Occlusion/diagnosis ; Coronary Occlusion/surgery ; Out-of-Hospital Cardiac Arrest/diagnosis ; Out-of-Hospital Cardiac Arrest/etiology ; Out-of-Hospital Cardiac Arrest/therapy ; Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction ; Heart ; Coronary Artery Disease
    Language English
    Publishing date 2024-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
    DOI 10.25270/jic/23.00115
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    Zs.A 3701: Show issues Location:
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    Zs.MO 272: Show issues
    Zs.MG 31: Show issues

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  9. Book ; Online: Tracing chirality from molecular organization to triply-periodic network assemblies

    Prasad, Ishan / Reddy, Abhiram / Grason, Gregory M.

    Threading biaxial twist through block copolymer gyroids

    2023  

    Abstract: Chirality transfer from the level of molecular structure up to mesoscopic lengthscales of supramolecular morphologies is a broad and persistent theme in self-assembled soft materials, from biological to synthetic matter. Here, we analyze the mechanism of ...

    Abstract Chirality transfer from the level of molecular structure up to mesoscopic lengthscales of supramolecular morphologies is a broad and persistent theme in self-assembled soft materials, from biological to synthetic matter. Here, we analyze the mechanism of chirality transfer in a prototypical self-assembly system, block copolymers (BCPs), in particular, its impact on one of the most complex and functionally vital phases: the cubic, triply-periodic, gyroid network. Motivated by recent experimental studies, we consider a self-consistent field model of ABC* triblock copolymers possessing an end-block of chain chemistry and examine the interplay between chirality at the scale of networks, in alternating double network phases, and the patterns of segmental order within tubular network domains. We show that while segments in gyroids exhibit twist in both polar and nematic segmental order parameters, the magnitude of net nematic twist is generically much larger than polar twist, and more surprising, {\it reverses handedness} relative to the sense of polar order as well as the sense of dihedral twist of the network. Careful analysis of the intra-domain nematic order reveals that this unique chirality transfer mechanism relies on the strongly biaxial nature of segmental order in BCP networks and relates the {\it biaxial twist} to complex patterns of frame rotation of the principal directors in the intra-domain texture. Finally, we show that this mechanism of twist reversal leads to chirality selection of alternating gyroid networks in ABC* triblocks, in the limit of very weak chirality .

    Comment: 14 pages, 8 figures, 5 appendices
    Keywords Condensed Matter - Soft Condensed Matter ; Condensed Matter - Materials Science
    Subject code 612
    Publishing date 2023-03-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Well-to-wake analysis of switchgrass to jet fuel via a novel co-fermentation of sugars and CO

    Pamula, Abhiram Siva Prasad / Lampert, David J / Atiyeh, Hasan K

    The Science of the total environment

    2021  Volume 782, Page(s) 146770

    Abstract: Lignocellulosic biomass such as switchgrass can be converted to n-butanol using fermentation, which can be further processed into jet fuel. Traditional acetone-butanol-ethanol (ABE) fermentation only converts sugars derived from switchgrass to ABE. Novel ...

    Abstract Lignocellulosic biomass such as switchgrass can be converted to n-butanol using fermentation, which can be further processed into jet fuel. Traditional acetone-butanol-ethanol (ABE) fermentation only converts sugars derived from switchgrass to ABE. Novel co-fermentation processes convert sugars and gas (CO
    MeSH term(s) Butanols ; Carbon Dioxide ; Fermentation ; Panicum ; Sugars
    Chemical Substances Butanols ; Sugars ; Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2021-03-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2021.146770
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    Zs.A 949: Show issues Location:
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