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Article ; Online: Inhibition of Na

Kingma, J G

Journal of cardiovascular pharmacology and therapeutics

2018 Volume 23, Issue 3, Page(s) 254–269

Abstract: Postischemic accumulation of intracellular ... ...

Abstract	Postischemic accumulation of intracellular Na
MeSH term(s)	Animals ; Cardiotonic Agents/administration & dosage ; Cardiotonic Agents/pharmacology ; Disease Models, Animal ; Dogs ; Female ; Guanidines/administration & dosage ; Guanidines/pharmacology ; Ischemic Preconditioning, Myocardial/methods ; Male ; Myocardial Infarction/etiology ; Myocardial Infarction/pathology ; Myocardial Infarction/prevention & control ; Myocardial Reperfusion Injury/drug therapy ; Sodium-Hydrogen Exchanger 1/antagonists & inhibitors ; Sulfones/administration & dosage ; Sulfones/pharmacology ; Time Factors
Chemical Substances	Cardiotonic Agents ; Guanidines ; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine ; Sodium-Hydrogen Exchanger 1 ; Sulfones
Language	English
Publishing date	2018-03-21
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1329372-2
ISSN	1940-4034 ; 1074-2484
ISSN (online)	1940-4034
ISSN	1074-2484
DOI	10.1177/1074248418755120
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Zs.A 4895: Show issues

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Article ; Online: Experienced disrespect & abuse during childbirth and associated birth characteristics: a cross-sectional survey in the Netherlands.

Leijerzapf, Denise R / van der Pijl, Marit S G / Hollander, Martine H / Kingma, Elselijn / de Jonge, Ank / Verhoeven, Corine J M

BMC pregnancy and childbirth

2024 Volume 24, Issue 1, Page(s) 170

Abstract: Background: Experiencing upsetting disrespect and abuse (D&A) during labour and birth negatively affects women's birth experiences. Knowing in what circumstances of birth women experience upsetting situations of D&A can create general awareness and help ...

Abstract	Background: Experiencing upsetting disrespect and abuse (D&A) during labour and birth negatively affects women's birth experiences. Knowing in what circumstances of birth women experience upsetting situations of D&A can create general awareness and help healthcare providers judge the need for extra attention in their care to help reduce these experiences. However, little is known about how different birth characteristics relate to the experience of D&A. Previous studies showed differences in birth experiences and experienced D&A between primiparous and multiparous women. This study explores, stratified for parity, (1) how often D&A are experienced in the Netherlands and are considered upsetting, and (2) which birth characteristics are associated with these upsetting experiences of D&A. Methods: For this cross-sectional study, an online questionnaire was set up and disseminated among women over 16 years of age who gave birth in the Netherlands between 2015 and 2020. D&A was divided into seven categories: emotional pressure, unfriendly behaviour/verbal abuse, use of force/physical violence, communication issues, lack of support, lack of consent and discrimination. Stratified for parity, univariable and multivariable logistic regression analyses were performed to examine which birth characteristics were associated with the upsetting experiences of different categories of D&A. Results: Of all 11,520 women included in this study, 45.1% of primiparous and 27.0% of multiparous women reported at least one upsetting experience of D&A. Lack of consent was reported most frequently, followed by communication issues. For both primiparous and multiparous women, especially transfer from midwife-led to obstetrician-led care, giving birth in a hospital, assisted vaginal birth, and unplanned cesarean section were important factors that increased the odds of experiencing upsetting situations of D&A. Among primiparous women, the use of medical pain relief was also associated with upsetting experiences of D&A. Conclusion: A significant number of women experience upsetting disrespectful and abusive care during birth, particularly when medical interventions are needed after the onset of labour, when care is transferred during birth, and when birth takes place in a hospital. This study emphasizes the need for improving quality of verbal and non-verbal communication, support and adequate decision-making and consent procedures, especially before, during, and after the situations of birth that are associated with D&A.
MeSH term(s)	Pregnancy ; Female ; Humans ; Parturition/psychology ; Cross-Sectional Studies ; Cesarean Section ; Netherlands ; Delivery, Obstetric ; Attitude of Health Personnel ; Maternal Health Services ; Quality of Health Care ; Professional-Patient Relations
Language	English
Publishing date	2024-02-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2059869-5
ISSN	1471-2393 ; 1471-2393
ISSN (online)	1471-2393
ISSN	1471-2393
DOI	10.1186/s12884-024-06360-y
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Article ; Online: Evaluation of regional lung mass and growth in neonates with bronchopulmonary dysplasia using ultrashort echo time magnetic resonance imaging.

Giltmier, Andrew J / Higano, Nara S / Woods, Jason C / Kingma, Paul S

Pediatric pulmonology

2023 Volume 59, Issue 1, Page(s) 55–62

Abstract: ... 49.9 g, 36.2 vs. 26.8 g, 29.5 vs. 23.1 g, respectively). Babies with BPD who survived to discharge ... to discharge (21.6 vs. 15.7 g/kg, p = .01). There was a significant association between the rate of lung mass ...

Abstract	Rationale: Bronchopulmonary dysplasia (BPD) is the most common long term pulmonary morbidity in premature infants and is characterized by impaired lung growth and development. We hypothesized that lung mass growth is a critical factor in determining outcomes in infants with BPD. Objectives: To measure regional lung density and mass in infants with BPD and compare to clinical variables. Methods: We conducted a retrospective cohort study of neonates (n = 5 controls, n = 46 with BPD). Lung mass and lung density were calculated using ultrashort echo time (UTE) magnetic resonance imaging (MRI). Measurements and main results: Lung mass increased with increasing corrected gestational age at the time of MRI in all patients. Total, right, and left lung mass in infants with BPD trended higher than control infants (65.7 vs. 49.9 g, 36.2 vs. 26.8 g, 29.5 vs. 23.1 g, respectively). Babies with BPD who survived to discharge had higher relative lung mass than control infants and infants with BPD that did not survive to discharge (21.6 vs. 15.7 g/kg, p = .01). There was a significant association between the rate of lung mass growth and linear growth at the time of MRI (p = .034). Conclusions: Infants with BPD are capable of building lung mass over time. While this lung mass growth in infants with BPD may not represent fully functional lung tissue, higher lung mass growth is associated with increased linear growth.
MeSH term(s)	Infant, Newborn ; Infant ; Humans ; Bronchopulmonary Dysplasia/complications ; Retrospective Studies ; Lung ; Infant, Premature ; Magnetic Resonance Imaging/methods ; Gestational Age
Language	English
Publishing date	2023-10-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	632784-9
ISSN	1099-0496 ; 8755-6863
ISSN (online)	1099-0496
ISSN	8755-6863
DOI	10.1002/ppul.26705
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Zs.A 2143: Show issues

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Article ; Online: Sex differences in CKD risk factors across ethnic groups.

Vosters, Taryn G / Kingma, Frouke M / Stel, Vianda S / van den Born, Bert-Jan H / Huisman, Brechje J M V / van Ittersum, Frans J / Jager, Kitty J / Vogt, Liffert / van Valkengoed, Irene

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

2024

Language	English
Publishing date	2024-02-08
Publishing country	England
Document type	Journal Article
ZDB-ID	90594-x
ISSN	1460-2385 ; 0931-0509
ISSN (online)	1460-2385
ISSN	0931-0509
DOI	10.1093/ndt/gfae038
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Zs.A 2198: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 329: Show issues

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Article: Best of both worlds? Helpers in a cooperative fairy-wren assist most to breeding pairs that comprise a potential mate and a relative.

Teunissen, Niki / Fan, Marie / Roast, Michael J / Hidalgo Aranzamendi, Nataly / Kingma, Sjouke A / Peters, Anne

Royal Society open science

2023 Volume 10, Issue 11, Page(s) 231342

Abstract: ... to lighten the workload of-or maintain social bonds with-breeders (e.g. kin, potential mates) who in turn ... can offer benefits to helpers (e.g. prolonged nepotism, future mating, future production of relatives). Here ...

Abstract	In cooperative breeders, individuals forego independent reproduction and help others raise offspring. Helping is proposed to be driven by indirect benefits from raising relatives, and/or direct benefits from raising additional recruits or helping itself. We propose that consideration of social context is also important, in particular the characteristics of the breeding pair: helping may also serve to lighten the workload of-or maintain social bonds with-breeders (e.g. kin, potential mates) who in turn can offer benefits to helpers (e.g. prolonged nepotism, future mating, future production of relatives). Here, we test this hypothesis, while controlling for potential direct and indirect benefits from raising offspring, in purple-crowned fairy-wrens (
Language	English
Publishing date	2023-11-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2787755-3
ISSN	2054-5703
ISSN	2054-5703
DOI	10.1098/rsos.231342
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Article ; Online: Sex differences in thermophysiological responses of elderly to low-intensity exercise during uncompensable heat strain.

Daanen, Hein A M / Dijkstra, Iris / Abbink, Emma / de Jong, Iris J / Wolf, S Tony / Bongers, Coen C W G / Hondema, Laurens S / Eijsvogels, Thijs M H / Kingma, Boris R M

European journal of applied physiology

2024

Abstract: Purpose: The rising frequency of extreme heat events poses an escalating threat of heat-related illnesses and fatalities, placing an additional strain on global healthcare systems. Whether the risk of heat-related issues is sex specific, particularly ... ...

Abstract	Purpose: The rising frequency of extreme heat events poses an escalating threat of heat-related illnesses and fatalities, placing an additional strain on global healthcare systems. Whether the risk of heat-related issues is sex specific, particularly among the elderly, remains uncertain. Methods: 16 men and 15 women of similar age (69 ± 5 years) were exposed to an air temperature of 39.1 ± 0.3 °C and a relative humidity (RH) of 25.1 ± 1.9%, during 20 min of seated rest and at least 40 min of low-intensity (10 W) cycling exercise. RH was gradually increased by 2% every 5 min starting at minute 30. We measured sweat rate, heart rate, thermal sensation, and the rise in gastrointestinal temperature (Tgi) and skin temperature (Tsk). Results: Tgi consistently increased from minute 30 to 60, with no significant difference between females and males (0.012 ± 0.004 °C/min vs. 0.011 ± 0.005 °C/min; p = 0.64). Similarly, Tsk increase did not differ between females and males (0.044 ± 0.007 °C/min vs. 0.038 ± 0.011 °C/min; p = 0.07). Females exhibited lower sweat rates than males (0.29 ± 0.06 vs. 0.45 ± 0.14 mg/m Conclusion: Elderly females exhibit significantly lower sweat rates than their male counterparts during low-intensity exercise at ambient temperatures of 39 °C when humidity exceeds 30%. However, both elderly males and females demonstrate a comparable rise in core temperature, skin temperature, and mean body temperature, indicating similar health-related risks associated with heat exposure.
Language	English
Publishing date	2024-03-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	124793-1
ISSN	1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
ISSN (online)	1439-6327 ; 1432-1025
ISSN	0301-5548 ; 1439-6319
DOI	10.1007/s00421-024-05457-8
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Uc I Zs.195: Show issues

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Article: Natural history of three late-diagnosed classic Galactosemia patients.

Quelhas, Dulce / Kingma, Sandra D K / Jonckheere, An I / Smeets-Peels, Claudia S / Gomes, Daniel Costa / Duro, José / Oliveira, Anabela / Matthijs, Gert / Steinbusch, Laura K M / Jaeken, Jaak / Rivera, Isabel / Rubio-Gozalbo, Estela

Molecular genetics and metabolism reports

2024 Volume 38, Page(s) 101057

Abstract: The authors report the natural history of three patients with late-diagnosed Classic Galactosemia (CG) (at 16, 19 and 28 years). This was due to a combination of factors: absence of neonatal screening, absence of some typical acute neonatal symptoms, and ...

Abstract	The authors report the natural history of three patients with late-diagnosed Classic Galactosemia (CG) (at 16, 19 and 28 years). This was due to a combination of factors: absence of neonatal screening, absence of some typical acute neonatal symptoms, and negative galactosemia screening. This report underlines the value of neonatal screening and the importance of further diagnostic testing in case of late-onset manifestations.
Language	English
Publishing date	2024-01-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2821908-9
ISSN	2214-4269
ISSN	2214-4269
DOI	10.1016/j.ymgmr.2024.101057
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Article ; Online: Validation of a wearable system for 3D ambulatory L5/S1 moment assessment during manual lifting using instrumented shoes and an inertial sensor suit.

Faber, G S / Kingma, I / Chang, C C / Dennerlein, J T / van Dieën, J H

Journal of biomechanics

2020 Volume 102, Page(s) 109671

Abstract: This study aimed to evaluate the accuracy of 3D L5/S1 moment estimates from an ambulatory measurement system consisting of a wearable inertial motion capture system (IMC) and instrumented force shoes (FSs), during manual lifting. Reference L5/S1 moments ... ...

Abstract	This study aimed to evaluate the accuracy of 3D L5/S1 moment estimates from an ambulatory measurement system consisting of a wearable inertial motion capture system (IMC) and instrumented force shoes (FSs), during manual lifting. Reference L5/S1 moments were calculated using an inverse dynamics bottom-up laboratory model (
MeSH term(s)	Adult ; Biomechanical Phenomena ; Female ; Hand/physiology ; Humans ; Lifting ; Male ; Monitoring, Physiologic/instrumentation ; Shoes ; Wearable Electronic Devices
Language	English
Publishing date	2020-01-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
ZDB-ID	218076-5
ISSN	1873-2380 ; 0021-9290
ISSN (online)	1873-2380
ISSN	0021-9290
DOI	10.1016/j.jbiomech.2020.109671
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Zs.A 700: Show issues

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Article ; Online: Busulfan target exposure attainment in children undergoing allogeneic hematopoietic cell transplantation: a single day versus a multiday therapeutic drug monitoring regimen.

Bognàr, T Tim / Kingma, J S Jurjen / Smeijsters, E H Erin / van der Elst, K C M Kim / de Kanter, C T M Klaartje / Lindemans, C A Caroline / Egberts, A C G Toine / Bartelink, I H Imke / Lalmohamed, A Arief

Bone marrow transplantation

2023 Volume 58, Issue 7, Page(s) 762–768

Abstract: Busulfan exposure has previously been linked to clinical outcomes, hence the need for therapeutic drug monitoring (TDM). Study objective was to evaluate the effect of day 1 TDM-guided dosing (regimen d1) versus days 1 + 2 TDM-guided dosing (regimen d1 + ... ...

Abstract	Busulfan exposure has previously been linked to clinical outcomes, hence the need for therapeutic drug monitoring (TDM). Study objective was to evaluate the effect of day 1 TDM-guided dosing (regimen d1) versus days 1 + 2 TDM-guided dosing (regimen d1 + 2) on attaining adequate busulfan exposure. In this observational study, we included all children receiving busulfan-based allogeneic hematopoietic cell transplantation. Primary outcome was the percentage of patients achieving busulfan target attainment in both TDM regimens. Secondary outcomes were the variance in busulfan exposure and day-4 clearance (Cl
MeSH term(s)	Child ; Humans ; Busulfan ; Drug Monitoring ; Hematopoietic Stem Cell Transplantation ; Transplantation Conditioning
Chemical Substances	Busulfan (G1LN9045DK)
Language	English
Publishing date	2023-03-31
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	632854-4
ISSN	1476-5365 ; 0268-3369 ; 0951-3078
ISSN (online)	1476-5365
ISSN	0268-3369 ; 0951-3078
DOI	10.1038/s41409-023-01971-z
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Zs.A 2168: Show issues

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Article ; Online: Conditioning Strategies Limit Cellular Injury?

J. G. Kingma

World Journal of Cardiovascular Diseases , Vol 04, Iss 11, Pp 539-

2014 Volume 547

Abstract: Evaluation of multiorgan protection strategies against ischemic injury in humans is essential to improve quality of life and reduce mortality. Over the past 40 years a host of pharmacologic and non-pharmacologic interventions have been evaluated with the ...

Abstract	Evaluation of multiorgan protection strategies against ischemic injury in humans is essential to improve quality of life and reduce mortality. Over the past 40 years a host of pharmacologic and non-pharmacologic interventions have been evaluated with the aim of limiting cell damage produced by ischemia-reperfusion injury. Different conditioning strategies, such as remote conditioning, are documented to mitigate ischemic injury in animal and human studies and may have remarkable clinical promise. However, successful clinical application of these interventions remains questionable since protection is known to be compromised in humans with comorbidities either with or without medications. Regardless, ongoing studies continue to examine the underlying mechanisms involved in this endogenous cytoprotective phenomenon to further its successful implementation in the clinical setting. In this review, we examine recent findings in support of remote conditioning stratagems for organ protection and their relevance for translation to clinical use.
Keywords	Remote Conditioning ; Ischemia ; Reperfusion ; Cellular Protection ; Blood Flow ; Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R
Subject code	610
Language	English
Publishing date	2014-10-01T00:00:00Z
Publisher	Scientific Research Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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