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  1. Article ; Online: Preoperative systemic inflammatory response index predicts the prognosis of patients with hepatocellular carcinoma after liver transplantation.

    Cui, Songping / Cao, Shuang / Chen, Qing / He, Qiang / Lang, Ren

    Frontiers in immunology

    2023  Volume 14, Page(s) 1118053

    Abstract: Background: Preoperative inflammatory status plays an important role in the prognosis of malignancy. We sought to explore the value of preoperative inflammatory biomarkers in predicting long-term outcomes of liver transplantation (LT) in patients with ... ...

    Abstract Background: Preoperative inflammatory status plays an important role in the prognosis of malignancy. We sought to explore the value of preoperative inflammatory biomarkers in predicting long-term outcomes of liver transplantation (LT) in patients with hepatocellular carcinoma (HCC).
    Method: Patients who underwent LT for HCC in our hospital between January 2010 and June 2020 were included in this study. Demographic, clinical, laboratory, and outcome data were obtained. The area under the curve (AUC) of the receiver operating characteristic curve was used to evaluate the predictive value of inflammatory biomarkers. The effectiveness of inflammatory biomarkers in predicting outcomes was analyzed by univariate and multivariate Cox proportional hazards analyses.
    Results: A total of 218 patients were included in the study, with a mean age of 53.9 ± 8.5 years. The AUC of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune inflammation index (SII), and systemic inflammatory response index (SIRI) for overall survival (OS) were 0.741, 0.731, 0.756, 0.746, and 0.749, respectively. Cox proportional hazards model indicated that SIRI > 1.25 was independently associated with low OS [hazard ratio (HR) = 2.258, P = 0.024]. PLR > 82.15 and SIRI > 0.95 were independently associated with low disease-free survival (HR = 1.492, P = 0.015; and HR = 1.732, P = 0.008, respectively). In the survival analysis, the prognosis of patients with high preoperative SIRI and PLR was significantly worse (P < 0.001).
    Conclusion: SIRI and PLR were useful prognostic markers for predicting patients with HCC after LT.
    MeSH term(s) Humans ; Middle Aged ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/pathology ; Liver Transplantation/adverse effects ; Retrospective Studies ; Prognosis ; Biomarkers ; Systemic Inflammatory Response Syndrome
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1118053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Allogeneic Vessels in Pancreaticoduodenectomy with Portal Vein Resection: Risk of Portal Vein Thrombosis and Prognosis.

    Cui, Songping / Wang, Hanxuan / Huang, Jincan / He, Qiang / Lyu, Shaocheng / Lang, Ren

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2023  Volume 27, Issue 12, Page(s) 2797–2805

    Abstract: Background: Allogeneic vessels (AV) are commonly used in pancreaticoduodenectomy (PD) with portal vein resection (PVR), but the epidemiological characteristics of portal vein thrombosis (PVT) are still unclear.: Methods: The clinicopathological data ... ...

    Abstract Background: Allogeneic vessels (AV) are commonly used in pancreaticoduodenectomy (PD) with portal vein resection (PVR), but the epidemiological characteristics of portal vein thrombosis (PVT) are still unclear.
    Methods: The clinicopathological data of patients who underwent PD combined with PVR in our hospital from January 2011 to October 2022 were retrospectively collected. All patients underwent regular contrast-enhanced CT of the abdomen after surgery to identify PVT or recurrence and metastasis of the tumor.
    Results: A total of 878 patients received PD, of which 213 patients who also underwent PVR were included in the study. Among them are 16 (7.5%) tangential/patch reconstructions, 51 (23.9%) end-to-end anastomosis, and 146 (68.5%) AV reconstructions. The cumulative incidence of PVT in 1 month, 3 months, 6 months, 1 year, 2 years, and 3 years after surgery was 0.9%, 7.3%, 7.3%, 15.9%, 23.4%, and 27.6%, respectively. The results of logistic regression analysis showed that diabetes, operation procedure, and AV reconstruction were independent risk factors for PVT (P < 0.05). In the Cox analysis, PVT was clearly correlated with tumor recurrence (P = 0.038, hazard ratio (HR) = 1.553) and overall survival (P = 0.044, HR = 1.592) of pancreatic cancer patients.
    Conclusion: The prevalence of PVT is high in PD with PVR, particularly in patients undergoing AV reconstructions. The occurrence of PVT has a clear correlation with the patient's long-term prognosis.
    MeSH term(s) Humans ; Pancreaticoduodenectomy/methods ; Retrospective Studies ; Portal Vein/surgery ; Portal Vein/pathology ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Venous Thrombosis/epidemiology ; Venous Thrombosis/etiology ; Liver Diseases/surgery ; Abdomen/surgery ; Hematopoietic Stem Cell Transplantation/adverse effects
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1007/s11605-023-05832-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A nomogram model to predict the portal vein thrombosis risk after surgery in patients with pancreatic cancer.

    Wang, Jing / Wang, Hanxuan / Li, Binglin / Cui, Songping / Lyu, Shaocheng / Lang, Ren

    Frontiers in surgery

    2023  Volume 10, Page(s) 1293004

    Abstract: Background: Portal vein thrombosis (PVT) is a common postoperative complication in patients with pancreatic cancer (PC), significantly affecting their quality of life and long-term prognosis. Our aim is to establish a new nomogram to predict the risk of ...

    Abstract Background: Portal vein thrombosis (PVT) is a common postoperative complication in patients with pancreatic cancer (PC), significantly affecting their quality of life and long-term prognosis. Our aim is to establish a new nomogram to predict the risk of PVT after PC surgery.
    Method: We collected data from 416 patients who underwent PC surgery at our hospital between January 2011 and June 2022. This includes 87 patients with PVT and 329 patients without PVT. The patients were randomly divided into a training group and a validation group at a ratio of 7:3. We constructed a nomogram model using the outcomes from both univariate and multivariate logistic regression analyses conducted on the training group. The nomogram's predictive capacity was assessed using calibration curve, receiver operating characteristic (ROC) curve, and decision curve analysis (DCA).
    Results: In the study, the prevalence of PVT was 20.9%. Age, albumin, vein reconstruction and preoperative D-dimer were independent related factors. The model achieved a C-index of 0.810 (95% confidence interval: 0.752-0.867), demonstrating excellent discrimination and calibration performance. The area under the ROC curve of the nomogram was 0.829 (95% CI: 0.750-0.909) in the validation group. DCA confirmed that the nomogram model was clinically useful when the incidence of PVT in patients was 5%-60%.
    Conclusion: We have established a high-performance nomogram for predicting the risk of PVT in patients undergoing PC surgery. This will assist clinical doctors in identifying individuals at high risk of PVT and taking appropriate preventive measures.
    Language English
    Publishing date 2023-12-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2023.1293004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply to "Ibuprofen and thromboembolism in SARS-COV2".

    Cui, Songping / Chen, Shuo / Ke, Lihui

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 9, Page(s) 2427–2428

    MeSH term(s) COVID-19 ; Humans ; Ibuprofen ; Pandemics ; SARS-CoV-2 ; Thromboembolism
    Chemical Substances Ibuprofen (WK2XYI10QM)
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: [Perioperative Venous Thromboembolism (VTE) Prophylaxis in Thoracic Cancer Patients: Chinese Experts Consensus - Interpretation of Perioperative Hypercoagulable State].

    Cui, Songping / Li, Hui

    Zhongguo fei ai za zhi = Chinese journal of lung cancer

    2019  Volume 22, Issue 12, Page(s) 752–756

    Abstract: Venous thromboembolism (VTE) is a common perioperative complication of lung cancer and a major cause of unexpected death in hospital. The clinical risk factors of VTE include: patients' factors (advanced age, obesity, etc.), tumor-related factors ( ... ...

    Abstract Venous thromboembolism (VTE) is a common perioperative complication of lung cancer and a major cause of unexpected death in hospital. The clinical risk factors of VTE include: patients' factors (advanced age, obesity, etc.), tumor-related factors (classification, staging, etc.), treatment-related factors (chemotherapy, surgery, etc.). In addition, tumor cells express cancer procoagulant (CP), tissue factor (TF), inflammatory factors or activate platelets, inflammatory cells and other related cells, directly or indirectly activate the coagulation process, and cause blood hypercoagulable state, thus promote the occurrence of VTE. At the same time, the relevant biomarkers can also reflect the perioperative coagulation status of patients, which is helpful to more accurately identify high-risk subgroups to establish more accurate and targeted anticoagulation strategies to prevent thrombosis in lung cancer patients.
    MeSH term(s) Biomarkers, Tumor/metabolism ; Consensus ; Humans ; Perioperative Period ; Risk Factors ; Thoracic Neoplasms/metabolism ; Thoracic Neoplasms/surgery ; Venous Thromboembolism/metabolism ; Venous Thromboembolism/surgery
    Chemical Substances Biomarkers, Tumor
    Language Chinese
    Publishing date 2019-12-24
    Publishing country China
    Document type Journal Article
    ZDB-ID 2438672-8
    ISSN 1999-6187 ; 1009-3419
    ISSN (online) 1999-6187
    ISSN 1009-3419
    DOI 10.3779/j.issn.1009-3419.2019.12.03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Venous thromboembolism in patients undergoing distal cholangiocarcinoma surgery: Prevalence, risk factors, and outcomes.

    Chen, Qing / Cui, Songping / Huang, Jincan / Wang, Jing / Wang, Di / Wang, Hanxuan / Lyu, Shaocheng / Lang, Ren

    Asian journal of surgery

    2023  Volume 46, Issue 9, Page(s) 3648–3655

    Abstract: Background: To investigate venous thromboembolism (VTE) in patients undergoing distal cholangiocarcinoma (dCCA) surgery, we performed a single-center study to assess its prevalence, risk factors, prognosis.: Method: We studied a total of 177 patients ...

    Abstract Background: To investigate venous thromboembolism (VTE) in patients undergoing distal cholangiocarcinoma (dCCA) surgery, we performed a single-center study to assess its prevalence, risk factors, prognosis.
    Method: We studied a total of 177 patients undergoing dCCA surgery from January 2017 to April 2022. Demographic, clinical data, laboratory data (including lower extremity ultrasound findings), and outcome variables were obtained, and compared between VTE and non-VTE groups.
    Results: Of the 177 patients undergoing dCCA surgery (aged 65.2 ± 9.6 years; 108 (61.0%) male), 64 patients developed VTE after surgery. Logistic multivariate analysis showed that, age, operation procedure, TNM stage, ventilator duration and preoperative D-dimer were independent risk factors. Based on these factors, we constructed the nomogram to predict VTE after dCCA for the first time. The areas under the receiver operating curve (ROC) of the nomogram were 0.80 (95% CI: 0.72-0.88) and 0.79 (95% CI: 0.73-0.89) in the training and validation groups, respectively. Patients developed VTE had a worse prognosis by Kaplan-Meier curve analysis (p = 0.001).
    Conclusion: The prevalence of VTE is high and is associated with adverse outcomes in patients undergoing dCCA surgery. We developed a nomogram assessing VTE risk, which may help clinicians to screen out people at high risk for VTE and to undertake rational preventive measures.
    MeSH term(s) Humans ; Male ; Female ; Venous Thromboembolism/epidemiology ; Prevalence ; Risk Factors ; Cholangiocarcinoma ; Bile Duct Neoplasms ; Bile Ducts, Intrahepatic ; Retrospective Studies
    Language English
    Publishing date 2023-02-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.02.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Prognostic and recurrent significance of SII in patients with pancreatic head cancer undergoing pancreaticoduodenectomy.

    Chen, Qing / Ren, Siqian / Cui, Songping / Huang, Jincan / Wang, Di / Li, Binglin / He, Qiang / Lang, Ren

    Frontiers in oncology

    2023  Volume 13, Page(s) 1122811

    Abstract: Background: To investigate the clinical significance of preoperative inflammatory status in patients with pancreatic head carcinoma (PHC), we performed a single-center study to assess it.: Method: We studied a total of 164 patients with PHC ... ...

    Abstract Background: To investigate the clinical significance of preoperative inflammatory status in patients with pancreatic head carcinoma (PHC), we performed a single-center study to assess it.
    Method: We studied a total of 164 patients with PHC undergoing PD surgery (with or without allogeneic venous replacement) from January 2018 to April 2022. Systemic immune-inflammation index (SII) was the most important peripheral immune index in predicting the prognosis according to XGBoost analysis. The optimal cutoff value of SII for OS was calculated according to Youden index based on the receiver operating characteristic (ROC) curve and the cohort was divided into Low SII group and High SII group. Demographic, clinical data, laboratory data, follow-up data variables were obtained and compared between the two groups. Kaplan-Meier curves, univariable and multivariable Cox regression models were used to determine the association between preoperative inflammation index, nutritional index and TNM staging system with OS and DFS respectively.
    Results: The median follow-up time was 16 months (IQR 23), and 41.4% of recurrences occurred within 1 year. The cutoff value of SII was 563, with a sensitivity of 70.3%, and a specificity of 60.7%. Peripheral immune status was different between the two groups. Patients in High SII group had higher PAR, NLR than those in Low SII group (P <0.01, <0.01, respectively), and lower PNI (P <0.01). Kaplan-Meier analysis showed significantly poorer OS and DFS (P < 0.001, <0.001, respectively) in patients with high SII. By using the multivariable Cox regression model, high SII (HR, 2.056; 95% CI, 1.082-3.905, P=0.028) was significant predictor of OS. Of these 68 high-risk patients who recurrence within one year, patients with widespread metastasis had lower SII and worse prognosis (P <0.01).
    Conclusion: High SII was significantly associated with poor prognosis in patients with PHC. However, in patients who recurrence within one year, SII was lower in patients at TNM stage III. Thus, care needs to be taken to differentiate those high-risk patients.
    Language English
    Publishing date 2023-05-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1122811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Influence of early-life factors on the development of endometriosis.

    Liu, Songping / Cui, Hongyan / Zhang, Qiong / Hua, Keqin

    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception

    2019  Volume 24, Issue 3, Page(s) 216–221

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Adult ; Breast Feeding/statistics & numerical data ; Case-Control Studies ; Cesarean Section/statistics & numerical data ; China/epidemiology ; Endometriosis/epidemiology ; Fathers/statistics & numerical data ; Female ; Humans ; Infant ; Infant, Newborn ; Middle Aged ; Pregnancy ; Premature Birth/epidemiology ; Prenatal Exposure Delayed Effects/epidemiology ; Retrospective Studies ; Risk Factors ; Smoking/epidemiology ; Uterine Hemorrhage/epidemiology ; Young Adult
    Language English
    Publishing date 2019-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1397560-2
    ISSN 1473-0782 ; 1362-5187
    ISSN (online) 1473-0782
    ISSN 1362-5187
    DOI 10.1080/13625187.2019.1602723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Supercooling of Water Controlled by Nanoparticles and Ultrasound.

    Cui, Wei / Jia, Lisi / Chen, Ying / Li, Yi'ang / Li, Jun / Mo, Songping

    Nanoscale research letters

    2018  Volume 13, Issue 1, Page(s) 145

    Abstract: Nanoparticles, including ... ...

    Abstract Nanoparticles, including Al
    Language English
    Publishing date 2018-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2253244-4
    ISSN 1556-276X ; 1931-7573
    ISSN (online) 1556-276X
    ISSN 1931-7573
    DOI 10.1186/s11671-018-2560-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: 2D Bismuth@N-Doped Carbon Sheets for Ultrahigh Rate and Stable Potassium Storage.

    Xu, Anding / Zhu, Qi / Li, Guilan / Gong, Caihong / Li, Xue / Chen, Huaming / Cui, Jie / Wu, Songping / Xu, Zhiguang / Yan, Yurong

    Small (Weinheim an der Bergstrasse, Germany)

    2022  Volume 18, Issue 44, Page(s) e2203976

    Abstract: Metallic Bi, as an alloying-type anode material, has demonstrated tremendous potential for practical application of potassium-ion batteries. However, the giant volume expansion, severe structure pulverization, and sluggish dynamics of Bi-based materials ... ...

    Abstract Metallic Bi, as an alloying-type anode material, has demonstrated tremendous potential for practical application of potassium-ion batteries. However, the giant volume expansion, severe structure pulverization, and sluggish dynamics of Bi-based materials result in unsatisfied rate performance and unstable cycling stability. Here, 2D bismuth@N-doped carbon sheets with BiOC bond and internal void space (2D Bi@NOC) are successfully fabricated via a self-template strategy to address these issues, which own ultrafast electrochemical kinetics and impressive long-term cycling stability for delivering an admirable capacity of 341.7 mAh g
    Language English
    Publishing date 2022-09-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202203976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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