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  1. Book: Are skin diseases systemic ones? / 3

    Kazandjieva, Jana / Darlenski, Razvigor / Tsankov, Nikolai

    (Clinics in dermatology ; volume 37, number 6 (November/December 2019))

    2019  

    Author's details guest ed.: Nikolai Tsankov ; Jana Kazandjieva ; Razvigor Darlenski
    Series title Clinics in dermatology ; volume 37, number 6 (November/December 2019)
    Are skin diseases systemic ones?
    Collection Are skin diseases systemic ones?
    Language English
    Size Seite 607-717, Illustrationen
    Publishing country United States
    Document type Book
    HBZ-ID HT020382812
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 972 -37,6- verfügbar in Königswinter Königswinter

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  2. Article ; Online: Achenbach's Syndrome after mRNA COVID-19 Vaccination.

    Darlenski, Razvigor / Gospodinova, Klimentina / Vassileva, Snejina

    Skinmed

    2023  Volume 21, Issue 5, Page(s) 375–376

    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171125-2
    ISSN 1751-7125 ; 1540-9740
    ISSN (online) 1751-7125
    ISSN 1540-9740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: The hen and the egg question in atopic dermatitis: allergy or eczema comes first.

    Allenova, Anastasiia / Darlenski, Razvigor

    Asthma research and practice

    2023  Volume 9, Issue 1, Page(s) 1

    Abstract: Atopic dermatitis (AD) as a chronic inflammatory systemic condition is far more than skin deep. Co-morbidities such as asthma and allergic rhinitis as well as the psychological impact influence seriously the quality of life of the patients. Recent ... ...

    Abstract Atopic dermatitis (AD) as a chronic inflammatory systemic condition is far more than skin deep. Co-morbidities such as asthma and allergic rhinitis as well as the psychological impact influence seriously the quality of life of the patients. Recent studies have shown that only 10% of atopic patients undergo full manifestation of the atopic march, while 40% demonstrate concomitant food allergy. Exposure to food allergens in the environment causes sensitization and food allergy through the disruption of the skin barrier, as in AD. Food allergy and AD are closely related. While not all AD patients have a food allergy, 20-40% of children with moderate to severe AD will have an IgE-mediated food allergy. It is known that they may coexist but it is unclear if food allergy worsens the course of AD. Experimental, clinical, and epidemiological studies have provided evidence of the primary role of an epidermal barrier defect in the development of sensitization to environmental allergens and that this process occurs in the damaged skin barrier rather than the gastrointestinal or respiratory tract. There is strong evidence for a connection between early AD onset and the development of other allergic diseases later in life.
    Language English
    Publishing date 2023-02-10
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2054-7064
    ISSN 2054-7064
    DOI 10.1186/s40733-023-00090-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: How do the skin barrier and microbiome adapt to the extra-uterine environment after birth? Implications for the clinical practice.

    Darlenski, Razvigor / Fluhr, Joachim W

    International journal of cosmetic science

    2023  Volume 45, Issue 3, Page(s) 288–298

    Abstract: The multiple protective functions of the skin derive from the interactions between epithelial skin and immune cells as well as the commensal microbiota. Developed in the last trimester of intra-uterine life, the skin barrier adapts dynamically after ... ...

    Abstract The multiple protective functions of the skin derive from the interactions between epithelial skin and immune cells as well as the commensal microbiota. Developed in the last trimester of intra-uterine life, the skin barrier adapts dynamically after birth. Specific differences in the structure and physiology have been disclosed between infant and adult skin. The stratum corneum of infants is thinner and structured by thicker corneocytes with a more anisotropic surface in comparison to adult skin. Lower levels of the natural moisturizing factor and its constituents, together with the increased protease activity in the epidermis result in dry baby skin and ongoing adaptation of the desquamation to the extra-uterine environment. Infant epidermis is characterized by an accelerated proliferation rate and clinically competent permeability barrier in term neonates, despite the higher baseline values of transepidermal water loss in infants. The skin surface of newborns is less acidic, which could increase susceptibility to diaper and atopic dermatitis. Immediately after birth, skin is colonized by commensal bacteria-a process dependent on the mode of delivery and of major importance for the maturation of the immune system. Skin bacterial diversity and dysbiosis have been related to different pathology such as atopic and seborrheic dermatitis. This paper focuses on the ongoing structural, functional and biochemical adaptation of the human skin barrier after birth. We discuss the interactions on the 'skin barrier/ microbiota/ immune system' axis and their role in the development of competent functional integrity of the epidermal barrier.
    MeSH term(s) Adult ; Infant ; Humans ; Infant, Newborn ; Skin ; Epidermis/pathology ; Dermatitis, Atopic ; Water ; Microbiota
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 198917-0
    ISSN 1468-2494 ; 0142-5463
    ISSN (online) 1468-2494
    ISSN 0142-5463
    DOI 10.1111/ics.12844
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2391: Show issues Location:
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  5. Article ; Online: Visible light spectrum light-emitting diode (LED) mask-induced cutaneous lupus erythematosus-like reaction.

    Kotirkova, Desislava / Kadurina, Miroslava / Kacheva, Margarita / Darlenski, Razvigor

    International journal of dermatology

    2023  Volume 62, Issue 11, Page(s) 1416–1417

    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: Probable contact urticaria caused by tacrolimus-containing ointment in the treatment of atopic dermatitis.

    Darlenski, Razvigor

    The journal of allergy and clinical immunology. In practice

    2018  Volume 7, Issue 5, Page(s) 1665–1667

    MeSH term(s) Child, Preschool ; Dermatitis, Atopic/drug therapy ; Female ; Histamine H1 Antagonists/therapeutic use ; Humans ; Immunosuppressive Agents/adverse effects ; Ointments ; Tacrolimus/adverse effects ; Urticaria/chemically induced ; Urticaria/drug therapy
    Chemical Substances Histamine H1 Antagonists ; Immunosuppressive Agents ; Ointments ; Tacrolimus (WM0HAQ4WNM)
    Language English
    Publishing date 2018-12-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2018.11.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 7086: Show issues Location:
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  7. Article: Delayed type hypersensitivity injection site reaction and tolerance induction to liraglutide for the treatment of obesity.

    Yaneva, Martina / Handjieva-Darlenska, Teodora / Kazandjieva, Jana / Darlenski, Razvigor

    JAAD case reports

    2023  Volume 38, Page(s) 100–101

    Language English
    Publishing date 2023-06-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.06.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Allergic contact dermatitis caused by topical propranolol therapy for infantile haemangioma.

    Mahmoud, Inaya / Kotirkova, Desislava / Gospodinova, Klimentina / Darlenski, Razvigor / Kazandjieva, Jana

    Contact dermatitis

    2023  Volume 89, Issue 1, Page(s) 62–63

    MeSH term(s) Humans ; Infant ; Propranolol/adverse effects ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Adrenergic beta-Antagonists/adverse effects ; Hemangioma/drug therapy
    Chemical Substances Propranolol (9Y8NXQ24VQ) ; Adrenergic beta-Antagonists
    Language English
    Publishing date 2023-04-03
    Publishing country England
    Document type Case Reports
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1116: Show issues Location:
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  9. Book: Are skin diseases systemic ones? / 2

    Kazandjieva, Jana / Darlenski, Razvigor / Tsankov, Nikolai

    (Clinics in dermatology ; 33,5)

    2015  

    Author's details guest ed.: Nikolai Tsankov ; Jana Kazandjieva ; Razvigor Darlenski
    Series title Clinics in dermatology ; 33,5
    Are skin diseases systemic ones?
    Collection Are skin diseases systemic ones?
    Language English
    Size S. 510 - 586 : Ill.
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT018813306
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 972 -33,5- verfügbar in Königswinter Königswinter

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  10. Book ; Collection: Are skin diseases systemic ones?

    Kazandjieva, Jana / Darlenski, Razvigor / Tsankov, Nikolai

    (Clinics in dermatology ; ...)

    2014  

    Author's details guest ed.: Nikolai Tsankov ; Jana Kazandjieva ; Razvigor Darlenski
    Series title Clinics in dermatology
    ...
    Language English
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Collection (display volumes)
    HBZ-ID HT018323488
    Database Catalogue ZB MED Medicine, Health

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