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  1. Article ; Online: Coding Error Resulting in Change in Secondary Outcome Scores in Trial of Safety and Benefit of Discontinuing Statin Therapy Among Terminally Ill Patients.

    Kutner, Jean S / Abernethy, Amy P

    JAMA internal medicine

    2018  Volume 179, Issue 1, Page(s) 126

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Patients ; Terminally Ill
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2018-12-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2018.7162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Demonstrating the learning health system through practical use cases.

    Abernethy, Amy P

    Pediatrics

    2014  Volume 134, Issue 1, Page(s) 171–172

    MeSH term(s) Crohn Disease/drug therapy ; Female ; Humans ; Male ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
    Chemical Substances Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2014-1182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A Balanced Approach to Physician Responsibilities: Oncologists' Duties toward Themselves.

    Abernethy, Amy P

    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

    2014  , Page(s) e9–e14

    Abstract: Although critical to the provision of best patient care, physician self-care is an underattended aspect of responsibility in the medical professions, including oncology. Neglecting self-care bears negative consequences for the individual oncologist, ... ...

    Abstract Although critical to the provision of best patient care, physician self-care is an underattended aspect of responsibility in the medical professions, including oncology. Neglecting self-care bears negative consequences for the individual oncologist, ranging from burnout and fatigue to interpersonal and relationship stress, addiction, and disruptive behavior. It may also contribute to medical errors, disinterest in or depersonalization of patient care, and lower quality of care. Because of its effect on physicians, patients, and the health care environment, physician self-care is increasingly recognized as an important professional responsibility. Nonetheless, professional obligations, competing demands on time, and personal priorities conspire to prevent a large proportion of oncologists from adequately attending to self-care in even simple ways, such as getting sufficient exercise and sleep. This chapter discusses the need for physician self-care and the repercussions of not meeting this fundamental responsibility. Self-care is described in the context of three life domains: professional, personal (physical, psychological, mental, and spiritual), and interpersonal (relationships, family, social, and community). Strategies are provided for caring for the self in each domain.
    Language English
    Publishing date 2014-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2431126-1
    ISSN 1548-8756 ; 1548-8748
    ISSN (online) 1548-8756
    ISSN 1548-8748
    DOI 10.14694/EdBook_AM.2012.32.e9
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  4. Article ; Online: Diversity, Equity, and Inclusion in Clinical Research: A Path Toward Precision Health for Everyone.

    Washington, Vindell / Franklin, Joseph B / Huang, Erich S / Mega, Jessica L / Abernethy, Amy P

    Clinical pharmacology and therapeutics

    2022  Volume 113, Issue 3, Page(s) 575–584

    Abstract: Healthcare disparities are a persistent societal problem. One of the contributing factors to this status quo is the lack of diversity and representativeness of research efforts, which result in nongeneralizable evidence that, in turn, provides suboptimal ...

    Abstract Healthcare disparities are a persistent societal problem. One of the contributing factors to this status quo is the lack of diversity and representativeness of research efforts, which result in nongeneralizable evidence that, in turn, provides suboptimal means to enable the best possible outcomes at the individual level. There are several strategies that research teams can adopt to improve the diversity, equity, and inclusion (DEI) of their efforts; these strategies span the totality of the research path, from initial design to the shepherding of clinical data through a potential regulatory process. These strategies include more intentionality and DEI-based goal-setting, more diverse research and leadership teams, better community engagement to set study goals and approaches, better tailored outreach interventions, decentralization of study procedures and incorporation of innovative technology for more flexible data collection, and self-surveillance to identify and prevent biases. Within their remit of overlooking research efforts, regulatory authorities, as stakeholders, also have the potential for a positive effect on the DEI of emerging clinical evidence. All these are implementable tools and mechanisms that can make study participation more approachable to diverse communities, and ultimately generate evidence that is more generalizable and a conduit for better outcomes. The research community has an imperative to make DEI principles key foundational aspects in study conduct in order to pursue better personalized medicine for diverse patient populations.
    MeSH term(s) Humans ; Diversity, Equity, Inclusion ; Precision Medicine ; Data Collection ; Leadership
    Language English
    Publishing date 2022-12-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 123793-7
    ISSN 1532-6535 ; 0009-9236
    ISSN (online) 1532-6535
    ISSN 0009-9236
    DOI 10.1002/cpt.2804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Digital Health COVID-19 Impact Assessment: Lessons Learned and Compelling Needs.

    Lee, Peter / Abernethy, Amy / Shaywitz, David / Gundlapalli, Adi V / Weinstein, Jim / Doraiswamy, P Murali / Schulman, Kevin / Madhavan, Subha

    NAM perspectives

    2022  Volume 2022

    Language English
    Publishing date 2022-01-18
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2578-6865
    ISSN (online) 2578-6865
    DOI 10.31478/202201c
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  6. Article ; Online: Harnessing the Power of Real-World Evidence (RWE): A Checklist to Ensure Regulatory-Grade Data Quality.

    Miksad, Rebecca A / Abernethy, Amy P

    Clinical pharmacology and therapeutics

    2017  Volume 103, Issue 2, Page(s) 202–205

    Abstract: The role of real-world evidence (RWE) in regulatory, drug development, and healthcare decision-making is rapidly expanding. Recent advances have increased the complexity of cancer care and widened the gap between randomized clinical trial (RCT) results ... ...

    Abstract The role of real-world evidence (RWE) in regulatory, drug development, and healthcare decision-making is rapidly expanding. Recent advances have increased the complexity of cancer care and widened the gap between randomized clinical trial (RCT) results and the evidence needed for real-world clinical decisions. Instead of remaining invisible, data from the >95% of cancer patients treated outside of clinical trials can help fill this void.
    MeSH term(s) Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Checklist ; Data Accuracy ; Data Mining/methods ; Databases, Factual ; Drug Development/methods ; Drug Discovery/methods ; Evidence-Based Medicine/methods ; Humans ; Learning ; Models, Theoretical ; Patient Safety ; Risk Assessment ; Translational Medical Research/methods
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2017-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123793-7
    ISSN 1532-6535 ; 0009-9236
    ISSN (online) 1532-6535
    ISSN 0009-9236
    DOI 10.1002/cpt.946
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  7. Article ; Online: PC-FACS.

    Abernethy, Amy P

    Journal of pain and symptom management

    2012  Volume 43, Issue 3, Page(s) 651–662

    Abstract: PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care), an electronic publication of the American Academy of Hospice and Palliative Medicine, provides palliative care clinicians with concise summaries of the most important findings ... ...

    Abstract PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care), an electronic publication of the American Academy of Hospice and Palliative Medicine, provides palliative care clinicians with concise summaries of the most important findings from more than 50 medical and scientific journals. Each month, structured summaries and insightful commentaries on 6-10 articles help palliative care clinicians stay on top of the research that is critical to contemporary practice. PC-FACS is free to AAHPM members and members can earn up to 3 CME credits quarterly. Following are excerpts from recent issues, and comments from readers are welcomed at resources@aahpm.org.
    MeSH term(s) Adult ; Allied Health Personnel/psychology ; Analgesics, Opioid/adverse effects ; Antidepressive Agents/therapeutic use ; Attitude of Health Personnel ; Clinical Trials, Phase I as Topic ; Cognition Disorders/therapy ; Conscious Sedation ; Death ; Depressive Disorder, Major/therapy ; Happiness ; Hematology/education ; Humans ; Infant, Newborn ; Intensive Care Units ; Medical Oncology/education ; Neoplasms/therapy ; Nursing Homes ; Pain/complications ; Palliative Care ; Phototherapy ; Right to Die ; Serotonin Plasma Membrane Transport Proteins/genetics
    Chemical Substances Analgesics, Opioid ; Antidepressive Agents ; SLC6A4 protein, human ; Serotonin Plasma Membrane Transport Proteins
    Language English
    Publishing date 2012-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639142-4
    ISSN 1873-6513 ; 0885-3924
    ISSN (online) 1873-6513
    ISSN 0885-3924
    DOI 10.1016/S0885-3924(12)00044-9
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    Zs.A 2252: Show issues Location:
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  8. Article ; Online: Pc-facs.

    Abernethy, Amy P

    Journal of pain and symptom management

    2011  Volume 42, Issue 1, Page(s) 162–167

    Abstract: PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care), an electronic publication of the American Academy of Hospice and Palliative Medicine, provides palliative care clinicians with concise summaries of the most important findings ... ...

    Abstract PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care), an electronic publication of the American Academy of Hospice and Palliative Medicine, provides palliative care clinicians with concise summaries of the most important findings from more than 50 medical and scientific journals. Each month, structured summaries and insightful commentaries on 6-10 articles help palliative care clinicians stay on top of the research that is critical to contemporary practice. PC-FACS is free to AAHPM members and members can earn up to 3 CME credits quarterly. Following are excerpts from recent issues, and comments from readers are welcomed at resources@aahpm.org.
    MeSH term(s) Hospice Care ; Humans ; Palliative Care ; Truth Disclosure
    Language English
    Publishing date 2011-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639142-4
    ISSN 1873-6513 ; 0885-3924
    ISSN (online) 1873-6513
    ISSN 0885-3924
    DOI 10.1016/S0885-3924(11)00284-3
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  9. Article ; Online: Small But Mighty: The Use of Real-World Evidence to Inform Precision Medicine.

    Miksad, Rebecca A / Samant, Meghna K / Sarkar, Somnath / Abernethy, Amy P

    Clinical pharmacology and therapeutics

    2019  Volume 106, Issue 1, Page(s) 87–90

    MeSH term(s) Computational Biology/methods ; Data Accuracy ; Endpoint Determination ; Humans ; Neoplasms/drug therapy ; Precision Medicine/methods ; Product Surveillance, Postmarketing/methods ; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors ; Research Design ; Selection Bias
    Chemical Substances Receptor Protein-Tyrosine Kinases (EC 2.7.10.1)
    Language English
    Publishing date 2019-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123793-7
    ISSN 1532-6535 ; 0009-9236
    ISSN (online) 1532-6535
    ISSN 0009-9236
    DOI 10.1002/cpt.1466
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  10. Article ; Online: "Learning health care" for patients and populations.

    Abernethy, Amy P

    The Medical journal of Australia

    2010  Volume 194, Issue 11, Page(s) 564

    Abstract: A patient-focused learning health system, using integrated data sources, will facilitate optimal care of individuals and result in better care of our populations and society. ...

    Abstract A patient-focused learning health system, using integrated data sources, will facilitate optimal care of individuals and result in better care of our populations and society.
    MeSH term(s) Australia ; Delivery of Health Care/organization & administration ; Evidence-Based Medicine ; Health Services/statistics & numerical data ; Health Services Needs and Demand ; Humans ; Quality Assurance, Health Care
    Language English
    Publishing date 2010-10-17
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/j.1326-5377.2011.tb03103.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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