LIVIVO - Search results -

Search results

Result 1 - 10 of total 11

Search options

Article: New approaches to combat

Gerits, Evelien / Verstraeten, Natalie / Michiels, Jan

Journal of oral microbiology

2017 Volume 9, Issue 1, Page(s) 1300366

Abstract: In nature, bacteria predominantly reside in structured, surface-attached communities embedded in a self-produced, extracellular matrix. These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are ... ...

Abstract	In nature, bacteria predominantly reside in structured, surface-attached communities embedded in a self-produced, extracellular matrix. These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are difficult to eradicate due to their resistance to antimicrobials and host defense mechanisms. This review focusses on the biofilm-forming periodontal bacterium
Language	English
Publishing date	2017-03-15
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2000-2297
ISSN	2000-2297
DOI	10.1080/20002297.2017.1300366
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

Gerits, Evelien / Spincemaille, Pieter / De Cremer, Kaat / De Brucker, Katrijn / Beullens, Serge / Thevissen, Karin / Cammue, Bruno P A / Vandamme, Katleen / Fauvart, Maarten / Verstraeten, Natalie / Michiels, Jan

Clinical and experimental dental research

2017 Volume 3, Issue 2, Page(s) 69–76

Abstract: Porphyromonas ... ...

Abstract	Porphyromonas gingivalis
Language	English
Publishing date	2017-04-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2829558-4
ISSN	2057-4347
ISSN	2057-4347
DOI	10.1002/cre2.65
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Implant functionalization with mesoporous silica: A promising antibacterial strategy, but does such an implant osseointegrate?

Vandamme, Katleen / Thevissen, Karin / Mesquita, Marcelo F / Coropciuc, Ruxandra-Gabriella / Agbaje, Jimoh / Thevissen, Patrick / da Silva, Wander José / Vleugels, Jozef / De Cremer, Kaat / Gerits, Evelien / Martens, Johan A / Michiels, Jan / Cammue, Bruno P A / Braem, Annabel

Clinical and experimental dental research

2020 Volume 7, Issue 4, Page(s) 502–511

Abstract: Objectives: New strategies for implant surface functionalization in the prevention of peri-implantitis while not compromising osseointegration are currently explored. The aim of this in vivo study was to assess the osseointegration of a titanium-silica ... ...

Abstract	Objectives: New strategies for implant surface functionalization in the prevention of peri-implantitis while not compromising osseointegration are currently explored. The aim of this in vivo study was to assess the osseointegration of a titanium-silica composite implant, previously shown to enable controlled release of therapeutic concentrations of chlorhexidine, in the Göttingen mini-pig oral model. Material and methods: Three implant groups were designed: macroporous titanium implants (Ti-Porous); macroporous titanium implants infiltrated with mesoporous silica (Ti-Porous + SiO Results: Bone-to-implant contact and peri-implant bone volume for Ti-Porous versus Ti-Porous + SiO Conclusions: Next-generation implants made of macroporous Ti infiltrated with mesoporous SiO
MeSH term(s)	Animals ; Anti-Bacterial Agents ; Dental Implants ; Peri-Implantitis/prevention & control ; Prostheses and Implants ; Silicon Dioxide ; Surface Properties ; Swine ; Swine, Miniature ; Titanium
Chemical Substances	Anti-Bacterial Agents ; Dental Implants ; Silicon Dioxide (7631-86-9) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2020-12-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2829558-4
ISSN	2057-4347 ; 2057-4347
ISSN (online)	2057-4347
ISSN	2057-4347
DOI	10.1002/cre2.389
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Repurposing Toremifene for Treatment of Oral Bacterial Infections.

Gerits, Evelien / Defraine, Valerie / Vandamme, Katleen / De Cremer, Kaat / De Brucker, Katrijn / Thevissen, Karin / Cammue, Bruno P A / Beullens, Serge / Fauvart, Maarten / Verstraeten, Natalie / Michiels, Jan

Antimicrobial agents and chemotherapy

2017 Volume 61, Issue 3

Abstract: The spread of antibiotic resistance and the challenges associated with antiseptics such as chlorhexidine have necessitated a search for new antibacterial agents against oral bacterial pathogens. As a result of failing traditional approaches, drug ... ...

Abstract	The spread of antibiotic resistance and the challenges associated with antiseptics such as chlorhexidine have necessitated a search for new antibacterial agents against oral bacterial pathogens. As a result of failing traditional approaches, drug repurposing has emerged as a novel paradigm to find new antibacterial agents. In this study, we examined the effects of the FDA-approved anticancer agent toremifene against the oral bacteria
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Antineoplastic Agents, Hormonal/pharmacology ; Biofilms/drug effects ; Biofilms/growth & development ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cell Membrane/ultrastructure ; Cell Membrane Permeability/drug effects ; Dental Plaque/drug therapy ; Dental Plaque/microbiology ; Drug Repositioning ; Drug Resistance, Multiple, Bacterial/physiology ; Humans ; Microbial Sensitivity Tests ; Periodontitis/drug therapy ; Periodontitis/microbiology ; Porphyromonas gingivalis/drug effects ; Porphyromonas gingivalis/metabolism ; Porphyromonas gingivalis/ultrastructure ; Streptococcus mutans/drug effects ; Streptococcus mutans/metabolism ; Streptococcus mutans/ultrastructure ; Titanium/analysis ; Toremifene/pharmacology
Chemical Substances	Anti-Bacterial Agents ; Antineoplastic Agents, Hormonal ; Toremifene (7NFE54O27T) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2017-02-23
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	217602-6
ISSN	1098-6596 ; 0066-4804
ISSN (online)	1098-6596
ISSN	0066-4804
DOI	10.1128/AAC.01846-16
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 809: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Einzelsignatur: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans.

Gerits, Evelien / Van der Massen, Isolde / Vandamme, Katleen / De Cremer, Kaat / De Brucker, Katrijn / Thevissen, Karin / Cammue, Bruno P A / Beullens, Serge / Fauvart, Maarten / Verstraeten, Natalie / Michiels, Jan

FEMS microbiology letters

2017 Volume 364, Issue 2

Abstract: Oral infections are among the most common diseases worldwide. Many protocols for the prevention and treatment of oral infections have been described, yet no golden standard has been developed so far. The antiseptic chlorhexidine and antibiotics are often ...

Abstract	Oral infections are among the most common diseases worldwide. Many protocols for the prevention and treatment of oral infections have been described, yet no golden standard has been developed so far. The antiseptic chlorhexidine and antibiotics are often used in these treatment procedures. However, long-term use of chlorhexidine can lead to side effects and extensive use of antibiotics can promote the development of antibiotic-resistant bacteria, which in turn can compromise the effectiveness of the treatment. Consequently, it remains important to search for new antibacterial agents for the treatment of oral infections. In this study, we report on the antibacterial activity of the antiasthma drug zafirlukast against oral pathogens Porphyromonas gingivalis and Streptococcus mutans. Furthermore, its activity against oral biofilms grown on titanium surfaces was confirmed. In addition, we demonstrated that zafirlukast displays no cytotoxicity against human osteoblasts. Combined, this study paves the way for further research to determine the potential of zafirlukast to be used as a new antibiotic against oral pathogens.
MeSH term(s)	Anti-Asthmatic Agents/pharmacology ; Anti-Asthmatic Agents/toxicity ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/toxicity ; Biofilms/drug effects ; Biofilms/growth & development ; Cell Line ; Cell Survival/drug effects ; Drug Repositioning ; Humans ; Microbial Sensitivity Tests ; Osteoblasts/drug effects ; Porphyromonas gingivalis/drug effects ; Porphyromonas gingivalis/physiology ; Streptococcus mutans/drug effects ; Streptococcus mutans/physiology ; Tosyl Compounds/pharmacology
Chemical Substances	Anti-Asthmatic Agents ; Anti-Bacterial Agents ; Tosyl Compounds ; zafirlukast (XZ629S5L50)
Language	English
Publishing date	2017-01-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	752343-9
ISSN	1574-6968 ; 0378-1097
ISSN (online)	1574-6968
ISSN	0378-1097
DOI	10.1093/femsle/fnx005
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1372: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo.

De Cremer, Kaat / Delattin, Nicolas / De Brucker, Katrijn / Peeters, Annelies / Kucharíková, Soña / Gerits, Evelien / Verstraeten, Natalie / Michiels, Jan / Van Dijck, Patrick / Cammue, Bruno P A / Thevissen, Karin

Antimicrobial agents and chemotherapy

2014 Volume 58, Issue 12, Page(s) 7606–7610

Abstract: We here report on the in vitro activity of toremifene to inhibit biofilm formation of different fungal and bacterial pathogens, including Candida albicans, Candida glabrata, Candida dubliniensis, Candida krusei, Pseudomonas aeruginosa, Staphylococcus ... ...

Abstract	We here report on the in vitro activity of toremifene to inhibit biofilm formation of different fungal and bacterial pathogens, including Candida albicans, Candida glabrata, Candida dubliniensis, Candida krusei, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis. We validated the in vivo efficacy of orally administered toremifene against C. albicans and S. aureus biofilm formation in a rat subcutaneous catheter model. Combined, our results demonstrate the potential of toremifene as a broad-spectrum oral antibiofilm compound.
MeSH term(s)	Administration, Oral ; Animals ; Anti-Infective Agents/pharmacology ; Biofilms/drug effects ; Biofilms/growth & development ; Candida/drug effects ; Candida/growth & development ; Candidiasis, Cutaneous/drug therapy ; Candidiasis, Cutaneous/microbiology ; Catheters, Indwelling ; Female ; Pseudomonas Infections/drug therapy ; Pseudomonas Infections/microbiology ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/growth & development ; Rats ; Rats, Sprague-Dawley ; Selective Estrogen Receptor Modulators/pharmacology ; Skin/drug effects ; Skin/microbiology ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/growth & development ; Staphylococcus epidermidis/drug effects ; Staphylococcus epidermidis/growth & development ; Toremifene/pharmacology
Chemical Substances	Anti-Infective Agents ; Selective Estrogen Receptor Modulators ; Toremifene (7NFE54O27T)
Language	English
Publishing date	2014-10-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	217602-6
ISSN	1098-6596 ; 0066-4804
ISSN (online)	1098-6596
ISSN	0066-4804
DOI	10.1128/AAC.03869-14
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 809: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Einzelsignatur: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa.

Gerits, Evelien / Blommaert, Eline / Lippell, Anna / O'Neill, Alex J / Weytjens, Bram / De Maeyer, Dries / Fierro, Ana Carolina / Marchal, Kathleen / Marchand, Arnaud / Chaltin, Patrick / Spincemaille, Pieter / De Brucker, Katrijn / Thevissen, Karin / Cammue, Bruno P A / Swings, Toon / Liebens, Veerle / Fauvart, Maarten / Verstraeten, Natalie / Michiels, Jan

PloS one

2016 Volume 11, Issue 5, Page(s) e0155139

Abstract: Nosocomial and community-acquired infections caused by multidrug resistant bacteria represent a major human health problem. Thus, there is an urgent need for the development of antibiotics with new modes of action. In this study, we investigated the ... ...

Abstract	Nosocomial and community-acquired infections caused by multidrug resistant bacteria represent a major human health problem. Thus, there is an urgent need for the development of antibiotics with new modes of action. In this study, we investigated the antibacterial characteristics and mode of action of a new antimicrobial compound, SPI031 (N-alkylated 3, 6-dihalogenocarbazol 1-(sec-butylamino)-3-(3,6-dichloro-9H-carbazol-9-yl)propan-2-ol), which was previously identified in our group. This compound exhibits broad-spectrum antibacterial activity, including activity against the human pathogens Staphylococcus aureus and Pseudomonas aeruginosa. We found that SPI031 has rapid bactericidal activity (7-log reduction within 30 min at 4x MIC) and that the frequency of resistance development against SPI031 is low. To elucidate the mode of action of SPI031, we performed a macromolecular synthesis assay, which showed that SPI031 causes non-specific inhibition of macromolecular biosynthesis pathways. Liposome leakage and membrane permeability studies revealed that SPI031 rapidly exerts membrane damage, which is likely the primary cause of its antibacterial activity. These findings were supported by a mutational analysis of SPI031-resistant mutants, a transcriptome analysis and the identification of transposon mutants with altered sensitivity to the compound. In conclusion, our results show that SPI031 exerts its antimicrobial activity by causing membrane damage, making it an interesting starting point for the development of new antibacterial therapies.
MeSH term(s)	Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/metabolism ; Biosynthetic Pathways/drug effects ; Carbazoles/chemistry ; Carbazoles/pharmacology ; Cell Division/drug effects ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cell Membrane Permeability/drug effects ; Drug Resistance, Bacterial/drug effects ; Fatty Acids/biosynthesis ; Gene Expression Profiling ; Gene Regulatory Networks/drug effects ; Genes, Bacterial ; Kinetics ; Lipid Metabolism/drug effects ; Lipid Metabolism/genetics ; Liposomes/chemistry ; Macromolecular Substances/metabolism ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Mutation/genetics ; Phospholipids/metabolism ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/genetics ; Sequence Analysis, DNA ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/genetics ; Time Factors
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; Carbazoles ; Fatty Acids ; Liposomes ; Macromolecular Substances ; Phospholipids
Language	English
Publishing date	2016-05-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0155139
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

2016 Volume 34, Issue 12, Page(s) 2191–2198

Abstract: Biofilm-associated infections, particularly those caused by Staphylococcus aureus, are a major cause of implant failure. Covalent coupling of broad-spectrum antimicrobials to implants is a promising approach to reduce the risk of infections. In this ... ...

Abstract	Biofilm-associated infections, particularly those caused by Staphylococcus aureus, are a major cause of implant failure. Covalent coupling of broad-spectrum antimicrobials to implants is a promising approach to reduce the risk of infections. In this study, we developed titanium substrates on which the recently discovered antibacterial agent SPI031, a N-alkylated 3, 6-dihalogenocarbazol 1-(sec-butylamino)-3-(3,6-dichloro-9H-carbazol-9-yl)propan-2-ol, was covalently linked (SPI031-Ti). We found that SPI031-Ti substrates prevent biofilm formation of S. aureus and Pseudomonas aeruginosa in vitro, as quantified by plate counting and fluorescence microscopy. To test the effectiveness of SPI031-Ti substrates in vivo, we used an adapted in vivo biomaterial-associated infection model in mice in which SPI031-Ti substrates were implanted subcutaneously and subsequently inoculated with S. aureus. Using this model, we found a significant reduction in biofilm formation (up to 98%) on SPI031-Ti substrates compared to control substrates. Finally, we demonstrated that the functionalization of the titanium surfaces with SPI031 did not influence the adhesion and proliferation of human cells important for osseointegration and bone repair. In conclusion, these data demonstrate the clinical potential of SPI031 to be used as an antibacterial coating for implants, thereby reducing the incidence of implant-associated infections. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:2191-2198, 2016.
MeSH term(s)	Animals ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/therapeutic use ; Carbazoles/pharmacology ; Carbazoles/therapeutic use ; Cell Adhesion/drug effects ; Cell Proliferation/drug effects ; Female ; Mice, Inbred BALB C ; Microbial Sensitivity Tests ; Prosthesis-Related Infections/prevention & control ; Pseudomonas aeruginosa/drug effects ; Staphylococcus aureus/drug effects ; Titanium
Chemical Substances	Anti-Infective Agents ; Carbazoles ; SPI031 ; Titanium (D1JT611TNE)
Language	English
Publishing date	2016-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	605542-4
ISSN	1554-527X ; 0736-0266
ISSN (online)	1554-527X
ISSN	0736-0266
DOI	10.1002/jor.23238
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1879: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa.

Evelien Gerits / Eline Blommaert / Anna Lippell / Alex J O'Neill / Bram Weytjens / Dries De Maeyer / Ana Carolina Fierro / Kathleen Marchal / Arnaud Marchand / Patrick Chaltin / Pieter Spincemaille / Katrijn De Brucker / Karin Thevissen / Bruno P A Cammue / Toon Swings / Veerle Liebens / Maarten Fauvart / Natalie Verstraeten / Jan Michiels

PLoS ONE, Vol 11, Iss 5, p e

2016 Volume 0155139

Abstract	Nosocomial and community-acquired infections caused by multidrug resistant bacteria represent a major human health problem. Thus, there is an urgent need for the development of antibiotics with new modes of action. In this study, we investigated the antibacterial characteristics and mode of action of a new antimicrobial compound, SPI031 (N-alkylated 3, 6-dihalogenocarbazol 1-(sec-butylamino)-3-(3,6-dichloro-9H-carbazol-9-yl)propan-2-ol), which was previously identified in our group. This compound exhibits broad-spectrum antibacterial activity, including activity against the human pathogens Staphylococcus aureus and Pseudomonas aeruginosa. We found that SPI031 has rapid bactericidal activity (7-log reduction within 30 min at 4x MIC) and that the frequency of resistance development against SPI031 is low. To elucidate the mode of action of SPI031, we performed a macromolecular synthesis assay, which showed that SPI031 causes non-specific inhibition of macromolecular biosynthesis pathways. Liposome leakage and membrane permeability studies revealed that SPI031 rapidly exerts membrane damage, which is likely the primary cause of its antibacterial activity. These findings were supported by a mutational analysis of SPI031-resistant mutants, a transcriptome analysis and the identification of transposon mutants with altered sensitivity to the compound. In conclusion, our results show that SPI031 exerts its antimicrobial activity by causing membrane damage, making it an interesting starting point for the development of new antibacterial therapies.
Keywords	Medicine ; R ; Science ; Q
Subject code	572
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity.

Bioorganic & medicinal chemistry letters

2014 Volume 24, Issue 23, Page(s) 5404–5408

Abstract: Pseudomonas aeruginosa strains resistant towards all currently available antibiotics are increasingly encountered, raising the need for new anti-pseudomonal drugs. We therefore conducted a medium-throughput screen of a small-molecule collection resulting ...

Abstract	Pseudomonas aeruginosa strains resistant towards all currently available antibiotics are increasingly encountered, raising the need for new anti-pseudomonal drugs. We therefore conducted a medium-throughput screen of a small-molecule collection resulting in the identification of the N-alkylated 3,6-dihalogenocarbazol 1-(sec-butylamino)-3-(3,6-dichloro-9H-carbazol-9-yl)propan-2-ol (MIC = 18.5 μg mL⁻¹). This compound, compound 1, is bacteriostatic towards a broad spectrum of Gram-positive and Gram-negative pathogens, including P. aeruginosa. Importantly, 1 also eradicates mature biofilms of P. aeruginosa. 1 displays no cytotoxicity against various human cell types, pointing to its potential for further development as a novel antibacterial drug.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Biofilms ; Carbazoles/analysis ; Carbazoles/chemistry ; Humans ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/isolation & purification
Chemical Substances	Anti-Bacterial Agents ; Carbazoles
Language	English
Publishing date	2014-12-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1063195-1
ISSN	1464-3405 ; 0960-894X
ISSN (online)	1464-3405
ISSN	0960-894X
DOI	10.1016/j.bmcl.2014.10.039
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3203: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito