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  1. Article ; Online: Quantifying direct CO

    Liu, Liting / Ouyang, Zhu / Hu, Chunsheng / Li, Jing

    The Science of the total environment

    2023  Volume 906, Page(s) 167603

    Abstract: Organic manure compost offers benefits like enhanced crop yield, improved soil health, and increased soil carbon storage. However, its application might elevate direct ... ...

    Abstract Organic manure compost offers benefits like enhanced crop yield, improved soil health, and increased soil carbon storage. However, its application might elevate direct CO
    MeSH term(s) Manure ; Fertilizers ; Zea mays ; Carbon Dioxide/analysis ; Soil ; Agriculture/methods ; Carbon
    Chemical Substances Manure ; Fertilizers ; Carbon Dioxide (142M471B3J) ; Soil ; Carbon (7440-44-0)
    Language English
    Publishing date 2023-10-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.167603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Correction: Biomimetic Antidote Nanoparticles: A Novel Strategy for Chronic Heavy Metal Poisoning.

    Wang, Hao / Yao, Qing / Zhu, Wenquan / Yang, Yang / Gao, Chunsheng / Chu, Xiaoyang / Han, Cuiyan

    AAPS PharmSciTech

    2023  Volume 24, Issue 5, Page(s) 110

    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2052070-0
    ISSN 1530-9932 ; 1530-9932
    ISSN (online) 1530-9932
    ISSN 1530-9932
    DOI 10.1208/s12249-022-02488-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Activatable dual-functional molecular agents for imaging-guided cancer therapy.

    Zhang, Peng / Zhu, Yaowei / Xiao, Chunsheng / Chen, Xuesi

    Advanced drug delivery reviews

    2023  Volume 195, Page(s) 114725

    Abstract: Theranostics has attracted great attention due to its ability to combine the real-time diagnosis of cancers with efficient treatment modalities. Activatable dual-functional molecular agents could be synthesized by covalently conjugating imaging agents, ... ...

    Abstract Theranostics has attracted great attention due to its ability to combine the real-time diagnosis of cancers with efficient treatment modalities. Activatable dual-functional molecular agents could be synthesized by covalently conjugating imaging agents, therapeutic agents, stimuli-responsive linkers and/or targeting molecules together. They could be selectively activated by overexpressed physiological stimuli or external triggers at the tumor sites to release imaging agents and cytotoxic drugs, thus offering many advantages for tumor imaging and therapy, such as a high signal-to-noise ratio, low systemic toxicity, and improved therapeutic effects. This review summarizes the recent advances of dual-functional molecular agents that respond to various physiological or external stimuli for cancer theranostics. The molecular designs, synthetic strategies, activatable mechanisms, and biomedical applications of these molecular agents are elaborated, followed by a brief discussion of the challenges and opportunities in this field.
    MeSH term(s) Humans ; Neoplasms/diagnostic imaging ; Neoplasms/drug therapy ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Theranostic Nanomedicine/methods
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2023-02-06
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 639113-8
    ISSN 1872-8294 ; 0169-409X
    ISSN (online) 1872-8294
    ISSN 0169-409X
    DOI 10.1016/j.addr.2023.114725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2241: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Cardiac tamponade caused by an ectopic intrapericardial thymic carcinoma.

    Zhu, Kai / Chen, Weijie / Pan, Sun / Wang, Chunsheng

    Cardiology journal

    2022  Volume 29, Issue 1, Page(s) 170–171

    MeSH term(s) Cardiac Tamponade/diagnostic imaging ; Cardiac Tamponade/etiology ; Cardiac Tamponade/surgery ; Humans ; Pericardial Effusion/diagnostic imaging ; Pericardial Effusion/etiology ; Pericardium/diagnostic imaging ; Thymoma/diagnosis ; Thymoma/diagnostic imaging ; Thymus Neoplasms/diagnosis ; Thymus Neoplasms/diagnostic imaging
    Language English
    Publishing date 2022-02-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2488680-4
    ISSN 1898-018X ; 1897-5593
    ISSN (online) 1898-018X
    ISSN 1897-5593
    DOI 10.5603/CJ.2022.0005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6770: Show issues Location:
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  5. Article: Effects of

    Yin, Hang / Zhao, Meirong / Pan, Gang / Zhang, Hongyu / Yang, Rui / Sun, Juanjuan / Yu, Zhu / Bai, Chunsheng / Xue, Yanlin

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1177031

    Abstract: This study aimed to evaluate the effects ... ...

    Abstract This study aimed to evaluate the effects of
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1177031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Abundance of Transgene Transcript Variants Associated with Somatically Active Transgenic

    Li, Chuxi / Cong, Chunsheng / Liu, Fangyuan / Yu, Qian / Zhan, Yuan / Zhu, Li / Li, Yubin

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: ... ...

    Abstract Helitrons
    MeSH term(s) Animals ; Zea mays/genetics ; Genome, Plant ; Base Sequence ; DNA Transposable Elements/genetics ; Plants/genetics ; Transgenes
    Chemical Substances T-DNA ; DNA Transposable Elements
    Language English
    Publishing date 2023-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A rational design of polymers through donor modulation to weaken the aggregation-caused quenching effect for NIR-II fluorescence imaging.

    Zhu, Yaowei / Li, Lili / Sun, Bin / Zhang, Min / Zhang, Chunmei / Xiao, Chunsheng / Chen, Li

    Journal of materials chemistry. B

    2023  Volume 11, Issue 10, Page(s) 2129–2134

    Abstract: The great tissue penetration depth and low tissue autofluorescence of NIR-II fluorescence imaging make it attractive ... ...

    Abstract The great tissue penetration depth and low tissue autofluorescence of NIR-II fluorescence imaging make it attractive for
    MeSH term(s) Animals ; Mice ; Polymers ; Prospective Studies ; Optical Imaging/methods
    Chemical Substances Polymers
    Language English
    Publishing date 2023-03-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d2tb02357a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Comprehensive elaboration of circular RNA in multiple myeloma.

    Zhu, Chunsheng / Guo, Aoxiang / Sun, Bao / Zhou, Zheng

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 971070

    Abstract: Circular RNAs (circRNAs), a novel category of endogenous non-coding RNAs, are usually well conserved across different species with a covalent closed-loop structure. Existing and emerging evidence confirms that circRNAs can function as regulators of ... ...

    Abstract Circular RNAs (circRNAs), a novel category of endogenous non-coding RNAs, are usually well conserved across different species with a covalent closed-loop structure. Existing and emerging evidence confirms that circRNAs can function as regulators of alternative splicing, microRNA and RNA-binding protein sponges and translation, as well as gene transcription. In consideration of their multi-faceted functions, circRNAs are critically involved in hematological malignancies including multiple myeloma (MM). In particular, circRNAs have been found to play vital roles in tumor microenvironment and drug resistance, which may grant them potential roles as biomarkers for MM diagnosis and targeted therapy. In this review, we comprehensively elaborate the current state-of-the-art knowledge of circRNAs in MM, and then focus on their potential as biomarkers in diagnosis and therapy of MM.
    Language English
    Publishing date 2022-08-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.971070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Performance of a non-irrigated bipolar radiofrequency ablation clamp on beating human hearts.

    Weng, Fan / Yan, Tao / Zhu, Miao / Zhu, Shijie / Zhu, Kai / Wang, Chunsheng / Zhao, Zongliang / Guo, Changfa

    International journal of cardiology

    2024  Volume 399, Page(s) 131749

    Abstract: Objective: This study is intended to examine the efficacy of a non-irrigated bipolar RF clamp and explore the factors that can influence its performance on beating human hearts using the electrophysiology mapping method.: Methods: A total of 83 ... ...

    Abstract Objective: This study is intended to examine the efficacy of a non-irrigated bipolar RF clamp and explore the factors that can influence its performance on beating human hearts using the electrophysiology mapping method.
    Methods: A total of 83 atrial fibrillation (AF) patients were included in this study. Based on the Body mass index (BMI, kg/m
    Results: 86.7% (72/83) PV isolation on the LPV and 72.3% (60/83) PV isolation on the RPV could be achieved respectively after performing a single time of surgical ablation. Three times of ablations resulted in 100.0% PV isolation on the left and right PVs. In the normal BMI group, the ratio of patients who achieved a complete PV isolation after a single time of ablation was 83.7% (36/43), which was higher than the 60.0% (24/40) in the overweight or obese group.
    Conclusions: Performing three times of ablations resulted in 100% PV isolation on the left and right PVs. The bipolar RF clamp had a better performance on the LPV than on the RPV. The patients' BMI also influenced the Atricure clamp' s performance.
    MeSH term(s) Humans ; Overweight ; Catheter Ablation/methods ; Pulmonary Veins/surgery ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Radiofrequency Ablation ; Obesity/surgery ; Treatment Outcome
    Language English
    Publishing date 2024-01-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2024.131749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1673: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article: Pharmacomicrobiomics and type 2 diabetes mellitus: A novel perspective towards possible treatment.

    Jia, Liyang / Huang, Shiqiong / Sun, Boyu / Shang, Yongguang / Zhu, Chunsheng

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1149256

    Abstract: Type 2 diabetes mellitus (T2DM), a major driver of mortality worldwide, is more likely to develop other cardiometabolic risk factors, ultimately leading to diabetes-related mortality. Although a set of measures including lifestyle intervention and ... ...

    Abstract Type 2 diabetes mellitus (T2DM), a major driver of mortality worldwide, is more likely to develop other cardiometabolic risk factors, ultimately leading to diabetes-related mortality. Although a set of measures including lifestyle intervention and antidiabetic drugs have been proposed to manage T2DM, problems associated with potential side-effects and drug resistance are still unresolved. Pharmacomicrobiomics is an emerging field that investigates the interactions between the gut microbiome and drug response variability or drug toxicity. In recent years, increasing evidence supports that the gut microbiome, as the second genome, can serve as an attractive target for improving drug efficacy and safety by manipulating its composition. In this review, we outline the different composition of gut microbiome in T2DM and highlight how these microbiomes actually play a vital role in its development. Furthermore, we also investigate current state-of-the-art knowledge on pharmacomicrobiomics and microbiome's role in modulating the response to antidiabetic drugs, as well as provide innovative potential personalized treatments, including approaches for predicting response to treatment and for modulating the microbiome to improve drug efficacy or reduce drug toxicity.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/drug therapy ; Hypoglycemic Agents/therapeutic use ; Hypoglycemic Agents/pharmacology ; Gastrointestinal Microbiome ; Microbiota ; Drug-Related Side Effects and Adverse Reactions
    Chemical Substances Hypoglycemic Agents
    Language English
    Publishing date 2023-03-23
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1149256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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