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  1. Book: Beta-adrenergic receptor blockers in hypertension

    Tobe, Sheldon W.

    (The Canadian journal of cardiology ; 30,5S = Suppl.)

    2014  

    Author's details guest ed. Sheldon W. Tobe
    Series title The Canadian journal of cardiology ; 30,5S = Suppl.
    Collection
    Language English
    Size A6, S53 S. : graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country Canada
    Document type Book
    HBZ-ID HT018348446
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Early Changes of Kidney Function Are a Tell for Heart Disease Risk.

    Tobe, Sheldon W

    Journal of the American Heart Association

    2022  Volume 11, Issue 21, Page(s) e027733

    MeSH term(s) Humans ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency ; Kidney ; Heart Diseases/epidemiology ; Heart Failure
    Language English
    Publishing date 2022-10-31
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.122.027733
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: [No title information]

    Marcusohn, Erez / Tobe, Sheldon W / Dueck, Andrew / Madan, Mina

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2024  Volume 196, Issue 4, Page(s) E136–E141

    Title translation La dénervation rénale dans le traitement de l’hypertension non contrôlée.
    MeSH term(s) Humans ; Hypertension ; Kidney ; Denervation
    Language French
    Publishing date 2024-02-04
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.230745-f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Renal denervation for uncontrolled hypertension.

    Marcusohn, Erez / Tobe, Sheldon W / Dueck, Andrew / Madan, Mina

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2023  Volume 195, Issue 43, Page(s) E1475–E1480

    MeSH term(s) Humans ; Hypertension/drug therapy ; Kidney ; Denervation ; Blood Pressure ; Treatment Outcome ; Antihypertensive Agents/therapeutic use
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-11-04
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.230745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: What Can Declining Kidney Function Tell Us About Heart Failure?

    Tobe, Sheldon W

    The Canadian journal of cardiology

    2018  Volume 34, Issue 10, Page(s) 1261–1263

    MeSH term(s) Biomarkers ; Cardiovascular Physiological Phenomena ; Heart Failure ; Humans ; Kidney ; Prognosis
    Chemical Substances Biomarkers
    Language English
    Publishing date 2018-08-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2018.08.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Evaluation of visual acuity in dry AMD patients after microcurrent electrical stimulation.

    Parkinson, Kevin M / Sayre, Eric C / Tobe, Sheldon W

    International journal of retina and vitreous

    2023  Volume 9, Issue 1, Page(s) 36

    Abstract: Background: To assess micro current to improve vision for dry age-related macular degeneration. Dry age-related macular degeneration is a major cause of blindness, disability, and severe erosion of quality of life, throughout the world. Beyond ... ...

    Abstract Background: To assess micro current to improve vision for dry age-related macular degeneration. Dry age-related macular degeneration is a major cause of blindness, disability, and severe erosion of quality of life, throughout the world. Beyond nutritional supplementation, there is no approved therapy.
    Methods: This was a prospective randomized sham controlled clinical trial for participants with confirmed dry AMD with documented visual loss. Participants were randomized three to one, to receive transpalpebral external micro current electrical stimulation with the MacuMira device. The Treatment group received four treatments in the first two weeks, and two further treatments at weeks 14 and 26. Differences in BCVA and contrast sensitivity (CS) were estimated with mixed-effects repeated measures analysis of variance.
    Results: Change of visual acuity with ETDRS assessment of number of letters read (NLR) and contrast sensitivity at week 4 and 30, compared to the first visit, between 43 treatment and 19 sham control participants. The Sham Control group had NLR of 24.2 (SD 7.1) at baseline, 24.2 (SD 7.2) at 4 weeks, and 22.1 (SD7.4) at 30 weeks. The Treatment group had NLR of 19.6 (SD 8.9) at baseline, 27.6 (SD 9.1) at 4 weeks, and 27.8 (SD 8.4) at 30 weeks. The change in NLR from baseline in the Treatment compared to the Sham control group was 7.7 (95% CI 5.7, 9.7, p < 0.001) at 4 weeks and 10.4 (95% CI 7.8, 13.1, p < 0.001) at 30 weeks. There were similar benefits in CS.
    Conclusions: This pilot study of transpalpebral microcurrent demonstrated improved visual measures and is very encouraging as a potential treatment for dry AMD.
    Trial registration: NCT02540148, ClinicalTrials.gov.
    Language English
    Publishing date 2023-06-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2836254-8
    ISSN 2056-9920
    ISSN 2056-9920
    DOI 10.1186/s40942-023-00471-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Risk of Chronic Kidney Disease in Hospitalized Patients with Hidradenitis Suppurativa.

    Almuhanna, Nouf / Tobe, Sheldon W / Alhusayen, Raed

    Dermatology (Basel, Switzerland)

    2023  Volume 239, Issue 6, Page(s) 912–918

    Abstract: Background: Hidradenitis suppurativa (HS) is associated with several comorbidities such as diabetes mellitus and cardiovascular diseases. These comorbidities are also risk factors for chronic kidney disease (CKD), yet little is known about the risk of ... ...

    Abstract Background: Hidradenitis suppurativa (HS) is associated with several comorbidities such as diabetes mellitus and cardiovascular diseases. These comorbidities are also risk factors for chronic kidney disease (CKD), yet little is known about the risk of CKD in HS patients.
    Objectives: The objective was to study the prevalence of CKD in HS patients.
    Methods: Cross-sectional population-based study using the United States National Inpatient Sample database between January 1, 2002 and December 31, 2012 was performed.
    Results: We identified 23,767 hospital admissions for HS patients and 95,068 admissions for age- and gender-matched controls. The prevalence of CKD in HS patients was 6.3% (1,497/23,767) compared to non-HS controls which was 4.3% (4,052/95,068). The association of CKD was strongest in HS patients, who were ≥60 years old, 16.9% (475/2,811), male 7.3% (695/9,556), obese 7.8% (407/5,209), diabetic 12.5% (890/7,105), hyperlipidemic 13.3% (416/3,126), and had cardiovascular diseases 12.5% (631/5,045). The crude odds ratio of CKD in HS patients was 1.5 (95% CI: 1.420-1.605) compared to non-HS patients. The association remained significant after adjusting for important covariates with adjusted odds ratio of CKD in HS patients of 1.1 (95% CI: 1.014-1.176) compared to non-HS patients.
    Conclusions: Our findings show that there is a possible association of HS with CKD. Any signs of CKD should be assessed by a nephrologist as early diagnosis can hopefully prevent further progression.
    MeSH term(s) Humans ; Male ; United States ; Middle Aged ; Hidradenitis Suppurativa/complications ; Hidradenitis Suppurativa/epidemiology ; Hidradenitis Suppurativa/diagnosis ; Cardiovascular Diseases/epidemiology ; Cross-Sectional Studies ; Comorbidity ; Diabetes Mellitus/epidemiology ; Renal Insufficiency, Chronic/epidemiology
    Language English
    Publishing date 2023-07-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000531960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Age matters in the treatment and management of hypertension.

    Tobe, Sheldon W

    Journal of the American Society of Hypertension : JASH

    2016  Volume 10, Issue 1, Page(s) 10–11

    MeSH term(s) Disease Management ; Humans ; Hypertension
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 2276144-5
    ISSN 1878-7436 ; 1933-1711
    ISSN (online) 1878-7436
    ISSN 1933-1711
    DOI 10.1016/j.jash.2015.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Angiotensin Receptor-Neprilysin Inhibitor Therapy for Heart Failure With Preserved Ejection Fraction Improves Renal Outcomes.

    Tobe, Sheldon W / Poon, Stephanie

    Circulation

    2020  Volume 142, Issue 13, Page(s) 1246–1248

    MeSH term(s) Angiotensin Receptor Antagonists/therapeutic use ; Heart Failure/diagnosis ; Heart Failure/drug therapy ; Humans ; Neprilysin ; Receptors, Angiotensin ; Stroke Volume
    Chemical Substances Angiotensin Receptor Antagonists ; Receptors, Angiotensin ; Neprilysin (EC 3.4.24.11)
    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.050398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Rise and Fall of Hypertension Control in Canada: The Beginning of the End or the End of the Beginning?

    Feldman, Ross D / Padwal, Raj S / Tobe, Sheldon W

    The Canadian journal of cardiology

    2021  Volume 37, Issue 5, Page(s) 679–682

    MeSH term(s) Canada/epidemiology ; Humans ; Hypertension/epidemiology ; Hypertension/prevention & control
    Language English
    Publishing date 2021-02-17
    Publishing country England
    Document type Editorial
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2021.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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