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Article ; Online: The comparisons of expression pattern reveal molecular regulation of fruit metabolites in S. nigrum and S. lycopersicum.

Heo, Jung / Bang, Woo Young / Jeong, Jae Cheol / Park, Sung-Chul / Lee, Je Min / Choi, Sungho / Lee, Byounghee / Lee, Young Koung / Kim, Keunhwa / Park, Soon Ju

Scientific reports

2022 Volume 12, Issue 1, Page(s) 5001

Abstract: ... uninvestigated due to limited genetic information. Here, we identified 47,470 unigenes of S. nigrum from three ... tissue-specific gene expression regulation. We compared gene expression patterns between S. nigrum and tomato (S ... that 9 out of 14 enzyme-coding genes were highly upregulated in the fruit of S. nigrum. Using CRISPR-Cas9 ...

Abstract	Solanum nigrum, known as black nightshade, is a medicinal plant that contains many beneficial metabolites in its fruit. The molecular mechanisms underlying the synthesis of these metabolites remain uninvestigated due to limited genetic information. Here, we identified 47,470 unigenes of S. nigrum from three different tissues by de novo transcriptome assembly, and 78.4% of these genes were functionally annotated. Moreover, gene ontology (GO) analysis using 18,860 differentially expressed genes (DEGs) revealed tissue-specific gene expression regulation. We compared gene expression patterns between S. nigrum and tomato (S. lycopersicum) in three tissue types. The expression patterns of carotenoid biosynthetic genes were different between the two species. Comparison of the expression patterns of flavonoid biosynthetic genes showed that 9 out of 14 enzyme-coding genes were highly upregulated in the fruit of S. nigrum. Using CRISPR-Cas9-mediated gene editing, we knocked out the R2R3-MYB transcription factor SnAN2 gene, an ortholog of S. lycopersicum ANTHOCYANIN 2. The mutants showed yellow/green fruits, suggesting that SnAN2 plays a major role in anthocyanin synthesis in S. nigrum. This study revealed the connection between gene expression regulation and corresponding phenotypic differences through comparative analysis between two closely related species and provided genetic resources for S. nigrum.
MeSH term(s)	Anthocyanins ; Fruit/genetics ; Fruit/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Plant ; Lycopersicon esculentum/genetics ; Lycopersicon esculentum/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Solanum nigrum/metabolism ; Transcription Factors/metabolism ; Transcriptome
Chemical Substances	Anthocyanins ; Plant Proteins ; Transcription Factors
Language	English
Publishing date	2022-03-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-09032-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A robust electrochemical sensor based on N,S-FeNi

Li, Yangguang / Yang, Qiaoran / Feng, Yifan / Ye, Bang-Ce

Mikrochimica acta

2023 Volume 190, Issue 4, Page(s) 150

Abstract: ... S-FeNi ...

Abstract	For practical analysis and simultaneous detection of arbutin (AR) and hydrochinone (HQ) in cosmetics, an electrochemical sensor has been designed based on nitrogen and sulfur co-doped Fe-Ni alloy (N,S-FeNi
Language	English
Publishing date	2023-03-23
Publishing country	Austria
Document type	Journal Article
ZDB-ID	89-9
ISSN	1436-5073 ; 0026-3672
ISSN (online)	1436-5073
ISSN	0026-3672
DOI	10.1007/s00604-023-05733-y
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Article ; Online: Poly(Ethylene Piperidinium)s for Anion Exchange Membranes.

Chen, Huanhuan / Bang, Ki-Taek / Tian, Ye / Hu, Chuan / Tao, Ran / Yuan, Yufei / Wang, Rui / Shin, Dong-Myeong / Shao, Minhua / Lee, Young Moo / Kim, Yoonseob

Angewandte Chemie (International ed. in English)

2023 Volume 62, Issue 38, Page(s) e202307690

Abstract: The lack of anion exchange membranes (AEMs) that possess both high hydroxide conductivity and stable mechanical and chemical properties poses a major challenge to the development of high-performance fuel cells. Improving one side of the balance between ... ...

Abstract	The lack of anion exchange membranes (AEMs) that possess both high hydroxide conductivity and stable mechanical and chemical properties poses a major challenge to the development of high-performance fuel cells. Improving one side of the balance between conductivity and stability usually means sacrificing the other. Herein, we used facile, high-yield chemical reactions to design and synthesize a piperidinium polymer with a polyethylene backbone for AEM fuel cell applications. To improve the performance, we introduced ionic crosslinking into high-cationic-ratio AEMs to suppress high water uptake and swelling while further improving the hydroxide conductivity. Remarkably, PEP80-20PS achieved a hydroxide conductivity of 354.3 mS cm
Language	English
Publishing date	2023-08-09
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2011836-3
ISSN	1521-3773 ; 1433-7851
ISSN (online)	1521-3773
ISSN	1433-7851
DOI	10.1002/anie.202307690
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Article ; Online: Phonon Boost Effect on the S

Bang, Yunkyu

Scientific reports

2019 Volume 9, Issue 1, Page(s) 3907

Abstract: ... scattering) phonon - contribute to boosting Tc of the S ...

Abstract	We showed that the all phonons - not only forward-scattering phonon but also local (all-momentum-scattering) phonon - contribute to boosting Tc of the S
Language	English
Publishing date	2019-03-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-40536-3
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Article ; Online: Assembly processes of bacterial and fungal communities in metal(loid)s smelter soil.

Li, Miaomiao / Yao, Jun / Sunahara, Geoffrey / Duran, Robert / Liu, Bang / Cao, Ying / Li, Hao / Pang, Wancheng / Liu, Houquan / Jiang, Shun / Zhu, Junjie / Zhang, Qinghua

Journal of hazardous materials

2023 Volume 451, Page(s) 131153

Abstract: ... the metal(loid)s biogeochemical cycles at smelters. Here, a systematic investigation combined geochemical ... of the bioavailable fractions of certain metal(loid)s on bacteria (Comamonadaceae and Rhodocyclaceae) and fungi ... s-polluted soils. ...

Abstract	There are few studies on concurrent bacterial and fungal community assembly processes that govern the metal(loid)s biogeochemical cycles at smelters. Here, a systematic investigation combined geochemical characterization, co-occurrence patterns, and assembly mechanisms of bacterial and fungal communities inhabiting soils around an abandoned arsenic smelter. Acidobacteriota, Actinobacteriota, Chloroflexi, and Pseudomonadota were dominant in bacterial communities, whereas Ascomycota and Basidiomycota dominated fungal communities. The random forest model indicated the bioavailable fractions of Fe (9.58%) were the main positive factor driving the beta diversity of bacterial communities, and the total N (8.09%) was the main negative factor for fungal communities. Microbe-contaminant interactions demonstrate the positive impact of the bioavailable fractions of certain metal(loid)s on bacteria (Comamonadaceae and Rhodocyclaceae) and fungi (Meruliaceae and Pleosporaceae). The fungal co-occurrence networks exhibited more connectivity and complexity than the bacterial networks. The keystone taxa were identified in bacterial (including Diplorickettsiaceae, norank_o_Candidatus_Woesebacteria, norank_o_norank_c_AT-s3-28, norank_o_norank_c_bacteriap25, and Phycisphaeraceae) and fungal (including Biatriosporaceae, Ganodermataceae, Peniophoraceae, Phaeosphaeriaceae, Polyporaceae, Teichosporaceae, Trichomeriaceae, Wrightoporiaceae, and Xylariaceae) communities. Meanwhile, community assembly analysis revealed that deterministic processes dominated the microbial community assemblies, which were highly impacted by pH, total N, and total and bioavailable metal(loid) content. This study provides helpful information to develop bioremediation strategies for the mitigation of metal(loid)s-polluted soils.
MeSH term(s)	Mycobiome ; Soil/chemistry ; Metals/analysis ; Bacteria ; Biodegradation, Environmental ; Soil Microbiology
Chemical Substances	Soil ; Metals
Language	English
Publishing date	2023-03-06
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2023.131153
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Article ; Online: Porous silicon surface modification via a microwave-induced in situ cyclic disulfide (S-S) cleavage and Si-S bond formation.

Oh, Ji Hyeon / Um, Hyeji / Park, Yoon Kyung / Kim, Min / Kim, Dopil / Bang, Eun-Kyoung / Kang, Rae Hyung / Kim, Dokyoung

Colloids and surfaces. B, Biointerfaces

2022 Volume 222, Page(s) 113055

Abstract: ... In this study, a new surface modification method of Si-H-terminated pSi materials via microwave-induced Si-S ... with the 5-membered cyclic disulfide (S-S) compound (DL-α-lipoic acid in this study) by microwave-induced ... in situ S-S bond cleavage and Si-S bond formation. This surface chemistry is fast responsive (<10 min) and ...

Abstract	Porous silicon (pSi) materials have gained a great deal of attention from various research fields, and their surface-functionalization is one of the critical points for their applications. In this study, a new surface modification method of Si-H-terminated pSi materials via microwave-induced Si-S bond formation is disclosed. The silicon hydride (Si-H) functionality on the pSi surface could react with the 5-membered cyclic disulfide (S-S) compound (DL-α-lipoic acid in this study) by microwave-induced in situ S-S bond cleavage and Si-S bond formation. This surface chemistry is fast responsive (<10 min) and more efficient than other methods such as vortexing, heating stirring, or ultrasonication. The reaction maintains the primary porous structure of pSi materials including pSi wafer, pSi rugate filer, and pSi nanoparticles. An additional functional group such as carboxylic acid is demonstrated to be readily introducible on the pSi surface for further applications. Overall, this study has successfully demonstrated the porous silicon surface modification via a microwave-induced in situ cyclic disulfide (S-S) cleavage and Si-S bond formation.
MeSH term(s)	Silicon/chemistry ; Porosity ; Microwaves ; Carboxylic Acids
Chemical Substances	Silicon (Z4152N8IUI) ; Carboxylic Acids
Language	English
Publishing date	2022-11-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1500523-9
ISSN	1873-4367 ; 0927-7765
ISSN (online)	1873-4367
ISSN	0927-7765
DOI	10.1016/j.colsurfb.2022.113055
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Article: [PROSI Mutation With Clinical Heterogeneity in Protein S Deficiency:Report of One Case].

Wei, Xin-Yu / Wang, Juan / Tan, Bang-Yun / Li, Zi-Jian

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

2023 Volume 45, Issue 5, Page(s) 863–866

Abstract: Reduced protein S activity is one of the high-risk factors for venous thromboembolism.Hereditary ... protein S deficiency is an autosomal dominant disorder caused by mutations in the PROS1 gene.We reported ...

Abstract	Reduced protein S activity is one of the high-risk factors for venous thromboembolism.Hereditary protein S deficiency is an autosomal dominant disorder caused by mutations in the PROS1 gene.We reported a female patient with a mutation of c.292 G>T in exon 3 of the PROS1 gene,which was identified by sequencing.The genealogical analysis revealed that the mutation probably originated from the patient's mother.After searching against the PROS1 gene mutation database and the relevant literature,we confirmed that this mutation was reported for the first time internationally.
MeSH term(s)	Humans ; Female ; Protein S/genetics ; Protein S Deficiency/genetics ; Pedigree ; Mutation
Chemical Substances	Protein S
Language	Chinese
Publishing date	2023-08-24
Publishing country	China
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	604853-5
ISSN	1000-503X
ISSN	1000-503X
DOI	10.3881/j.issn.1000-503X.15541
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Article ; Online: The ramification of Cameroon’s Anglophone crisis

Henry Ngenyam Bang / Roland Azibo Balgah

Journal of International Humanitarian Action, Vol 7, Iss 1, Pp 1-

conceptual analysis of a looming “Complex Disaster Emergency”

2022 Volume 25

Abstract: Abstract One of Africa’s newest struggles for liberation: Cameroon’s Anglophone crisis ... involving document/content analysis, we apply the Robert Strauss Centre’s complex emergency framework ... in the conflict region, and by applying the Robert Strauss Centre’s complex emergency framework, this article ...

Abstract	Abstract One of Africa’s newest struggles for liberation: Cameroon’s Anglophone crisis, which emerged from legal and education grievances in 2016, rapidly escalated into a secessionist political conflict that is threatening the unity of the country, with potential to degenerate into a complex emergency. In an exploratory, qualitative, analytical, and descriptive case study research tradition involving document/content analysis, we apply the Robert Strauss Centre’s complex emergency framework to investigate the potential of the Anglophone crisis, whose ramifications lead us to consider it an acute complex emergency. Our contention is based on the fact that 72.5% of the variables in all the complex emergencies fall within the relevant to extremely relevant ranking criteria. Furthermore, the establishment of a nexus between the Anglophone crisis and a natural hazard-induced disaster suggest an escalation of the crisis to an unbearable level. Using the high probability of a novel eruption at Mt. Cameroon coupled with the eminent threat of the spread of the COVID-19 virus, we contend that unless otherwise, the crisis has immense potential to cumulatively evolve into a “Complex Disaster Emergency” (CDE) in the Anglophone regions of Cameroon. Amidst the existential challenges in providing humanitarian assistance in the conflict region, and by applying the Robert Strauss Centre’s complex emergency framework, this article concludes with an early warning for an impending CDE that could heighten humanitarian challenges unless there is foresight and goodwill by relevant actors to immediately commence a process of adequate contingency planning.
Keywords	Complex emergency ; Anglophone crisis ; Cameroon ; Human-induced disaster ; Complex Disaster Emergency ; Human rights violation ; Anthropology ; GN1-890 ; International relations ; JZ2-6530
Subject code	710
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mucocutaneous manifestations of Behçet’s disease

Doyoung Kim / Koichiro Nakamura / Fumio Kaneko / Erkan Alpsoy / Dongsik Bang

Frontiers in Medicine, Vol

Pathogenesis and management from perspectives of vasculitis

2022 Volume 9

Abstract: Behçet’s disease (BD) is a systemic inflammatory disorder characterized by vasculitis affecting ...

Abstract	Behçet’s disease (BD) is a systemic inflammatory disorder characterized by vasculitis affecting blood vessels of any caliber or type. It can present with a wide spectrum of vasculitic lesions, including erythema nodosum-like lesions and retinal vasculitis, and may also lead to larger vessel diseases, such as aortic aneurysm and deep vein thrombosis. The full etiology of BD remains unclear, but it is considered a polygenetic disease with multiple genetic risk factors that promote immune dysregulation and thrombophilia. Inflammation can be triggered by environmental factors, such as bacteria or viruses, and the dysregulation of innate and adaptive immune cell subsets. Neutrophils and lymphocytes are the primary players involved in BD pathogenesis, with specific innate (i.e., neutrophil-derived reactive oxygen species and neutrophil extracellular traps) and adaptive (i.e., anti-endothelial cell antibodies) processes inducing endothelial cell activation and chemotaxis of inflammatory cells, leading to coagulation and vasculitis. These inflammation-induced vasculitic or vasculopathic features are observed in most mucocutaneous BD lesions, although vasculitis per se is often pathologically evident only during a brief period of the disease process. Due to the multifactorial nature of BD-associated inflammation, broad-spectrum anti-inflammatory medications, including glucocorticoids and immunosuppressive drugs, have been the mainstay for managing BD. In addition, inhibitors of interleukin (IL)-1, tumor necrosis factor (TNF)-α, and IL-17, which target innate and adaptive immune functions dysregulated in BD, have emerged as promising new therapeutics. In this review, we discuss the muco-cutaneous manifestations of BD by focusing on the underlying vasculitic components in their pathologies, as well as the current array of treatment options.
Keywords	Behçet’s disease ; vasculitis ; mucocutaneous ; pathogenesis ; thrombosis ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The zinc finger protein DHHC09 S-acylates the kinase STRK1 to regulate H2O2 homeostasis and promote salt tolerance in rice.

Tian, Ye / Zeng, Hui / Wu, Ji-Cai / Dai, Gao-Xing / Zheng, He-Ping / Liu, Cong / Wang, Yan / Zhou, Zheng-Kun / Tang, Dong-Ying / Deng, Guo-Fu / Tang, Wen-Bang / Liu, Xuan-Ming / Lin, Jian-Zhong

The Plant cell

2024 Volume 36, Issue 4, Page(s) 919–940

Abstract: Soil salinity results in oxidative stress and heavy losses to crop production. The S-acylated ... CatC) to improve rice (Oryza sativa L.) salt tolerance, but the molecular mechanism underlying its S ... zinc finger protein DHHC09 S-acylates STRK1 at Cys5, Cys10, and Cys14 and promotes salt and oxidative stress ...

Abstract	Soil salinity results in oxidative stress and heavy losses to crop production. The S-acylated protein SALT TOLERANCE RECEPTOR-LIKE CYTOPLASMIC KINASE 1 (STRK1) phosphorylates and activates CATALASE C (CatC) to improve rice (Oryza sativa L.) salt tolerance, but the molecular mechanism underlying its S-acylation involved in salt signal transduction awaits elucidation. Here, we show that the DHHC-type zinc finger protein DHHC09 S-acylates STRK1 at Cys5, Cys10, and Cys14 and promotes salt and oxidative stress tolerance by enhancing rice H2O2-scavenging capacity. This modification determines STRK1 targeting to the plasma membrane or lipid nanodomains and is required for its function. DHHC09 promotes salt signaling from STRK1 to CatC via transphosphorylation, and its deficiency impairs salt signal transduction. Our findings demonstrate that DHHC09 S-acylates and anchors STRK1 to the plasma membrane to promote salt signaling from STRK1 to CatC, thereby regulating H2O2 homeostasis and improving salt stress tolerance in rice. Moreover, overexpression of DHHC09 in rice mitigates grain yield loss under salt stress. Together, these results shed light on the mechanism underlying the role of S-acylation in RLK/RLCK-mediated salt signal transduction and provide a strategy for breeding highly salt-tolerant rice.
MeSH term(s)	Salt Tolerance/genetics ; Oryza/metabolism ; Hydrogen Peroxide/metabolism ; Homeostasis ; Zinc Fingers ; Plant Proteins/genetics ; Plant Proteins/metabolism
Chemical Substances	Hydrogen Peroxide (BBX060AN9V) ; Plant Proteins
Language	English
Publishing date	2024-01-05
Publishing country	England
Document type	Journal Article
ZDB-ID	623171-8
ISSN	1532-298X ; 1040-4651
ISSN (online)	1532-298X
ISSN	1040-4651
DOI	10.1093/plcell/koae001
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