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  1. Article: Respirators evaluated by fit testing.

    Kleinjohann, Lukas / Lange, Christoph

    ERJ open research

    2020  Volume 6, Issue 4

    Abstract: FFP2/KN95 respirators can vary greatly in their ability to protect the wearer. Fit testing of respirators should be performed by all healthcare workers at risk for airborne transmitted diseases like #COVID19, #influenza or # ... ...

    Abstract FFP2/KN95 respirators can vary greatly in their ability to protect the wearer. Fit testing of respirators should be performed by all healthcare workers at risk for airborne transmitted diseases like #COVID19, #influenza or #tuberculosis
    Language English
    Publishing date 2020-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00581-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Learning-based Position and Stiffness Feedforward Control of Antagonistic Soft Pneumatic Actuators using Gaussian Processes

    Habich, Tim-Lukas / Kleinjohann, Sarah / Schappler, Moritz

    2023  

    Abstract: Variable stiffness actuator (VSA) designs are manifold. Conventional model-based control of these nonlinear systems is associated with high effort and design-dependent assumptions. In contrast, machine learning offers a promising alternative as models ... ...

    Abstract Variable stiffness actuator (VSA) designs are manifold. Conventional model-based control of these nonlinear systems is associated with high effort and design-dependent assumptions. In contrast, machine learning offers a promising alternative as models are trained on real measured data and nonlinearities are inherently taken into account. Our work presents a universal, learning-based approach for position and stiffness control of soft actuators. After introducing a soft pneumatic VSA, the model is learned with input-output data. For this purpose, a test bench was set up which enables automated measurement of the variable joint stiffness. During control, Gaussian processes are used to predict pressures for achieving desired position and stiffness. The feedforward error is on average 11.5% of the total pressure range and is compensated by feedback control. Experiments with the soft actuator show that the learning-based approach allows continuous adjustment of position and stiffness without model knowledge.

    Comment: Accepted for publication at IEEE-RAS International Conference on Soft Robotics (RoboSoft) 2023
    Keywords Electrical Engineering and Systems Science - Systems and Control ; Computer Science - Robotics
    Subject code 629
    Publishing date 2023-03-03
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Testing the Proper Fit Of Respirator Masks During the COVID-19 Pandemic–A Study Among Medical Staff.

    Schumacher, Jan / Lange, Christoph / Kleinjohann, Lukas / Carvalho, Clarissa

    Deutsches Arzteblatt international

    2021  Volume 118, Issue 14, Page(s) 250–251

    MeSH term(s) COVID-19 ; Humans ; Masks ; Occupational Exposure ; Pandemics/prevention & control ; SARS-CoV-2 ; Ventilators, Mechanical
    Language English
    Publishing date 2021-06-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2021.0186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Respirators evaluated by fit testing

    Lukas Kleinjohann / Christoph Lange

    ERJ Open Research, Vol 6, Iss

    2020  Volume 4

    Keywords Medicine ; R
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher European Respiratory Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Korrespondenz. Kunmitteilung: Dichtsitzprüfung von Atemschutzmasken während der COVID-ID-Pandemie Untersuchung bei medizinischen Mitarbeitern

    Schumacher, Jan / Lange, Christoph / Kleinjohann, Lukas / Carvalho, Clarissa

    Deutsches Ärzteblatt : Ausgabe A, Praxis-Ausgabe : niedergelassene Ärzte

    2021  Volume 118, Issue 14, Page(s) 250

    Language German
    Document type Article
    ZDB-ID 1453475-7
    ISSN 0012-1207
    Database Current Contents Medicine

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  6. Article ; Online: Impact of antibiotic intake on the incidence of extended-spectrum β-lactamase-producing Enterobacterales in sub-Saharan Africa: results from a community-based longitudinal study.

    Heinemann, Melina / Kleinjohann, Lukas / Rolling, Thierry / Winter, Doris / Hackbarth, Nina / Ramharter, Michael / Addo, Marylyn / Eibach, Daniel / Phillips, Richard O / Owusu-Ofori, Alex / Vinnemeier, Christof D

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2022  Volume 29, Issue 3, Page(s) 340–345

    Abstract: Objectives: The global prevalence of intestinal extended-spectrum β-lactamase-producing Enterobacterales (ESBL-PE) is approximately 17% in communities, with significant variations among regions. This longitudinal study aimed to assess the impact of ... ...

    Abstract Objectives: The global prevalence of intestinal extended-spectrum β-lactamase-producing Enterobacterales (ESBL-PE) is approximately 17% in communities, with significant variations among regions. This longitudinal study aimed to assess the impact of antibiotic intake on the incidence of intestinal ESBL-PE in Ghanaian pharmacy customers outside of hospitals.
    Methods: Screening for ESBL-PE was performed in four independent pharmacies in Kumasi, Ghana, using rectal swabs and an ESBL-PE-selective medium. Pharmacy customers purchasing antibiotics were recruited, and those buying non-antibiotic drugs served as controls. Participants who were negative for ESBL-PE provided follow-up swabs for up to 28 days.
    Results: At baseline, 302 (75%) of 404 participants were colonized with ESBL-PE. Sixty-three participants who were negative for ESBL-PE at baseline received per-protocol follow-up, including 28 individuals who took antibiotics and 35 controls. The cumulative proportions of ESBL-PE in the antibiotics and control groups were 71% (20/28) and 54% (19/35) at the first follow-up (p 0.258), 86% (24/28) and 80% (28/35) at the second follow-up (p 0.741) and 86% (24/28) and 94% (33/35) at the third follow-up (p 0.393), respectively.
    Discussion: The rate of intestinal ESBL-PE carriage among pharmacy customers outside of hospitals was higher than expected at baseline and further increased during the 28 days of follow-up, irrespective of antibiotic intake. This alarming finding needs to be considered in the antibiotic treatment of outpatients and emphasizes the urgent need for improved prevention strategies, development of new antibiotic drugs and potential future elimination strategies. Further longitudinal studies on ESBL-PE in African communities, also outside of pharmacy settings, are required.
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Enterobacteriaceae Infections/epidemiology ; Enterobacteriaceae ; Longitudinal Studies ; Ghana ; Incidence ; beta-Lactamases ; Risk Factors ; Gammaproteobacteria
    Chemical Substances Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2022-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2022.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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