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  1. Article: Author Reply: Therapeutic Drug Monitoring of Isavuconazole: Lessons Learnt from a Real-life Setting in a Tertiary Care Center in India.

    Prayag, Parikshit Shirish

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 27, Issue 6, Page(s) 451

    Abstract: How to cite this ... ...

    Abstract How to cite this article
    Language English
    Publishing date 2023-05-18
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Respiratory Care for Severe COVID-19.

    Prayag, Shirish

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2020  Volume 24, Issue 7, Page(s) 493–495

    Abstract: ... to COVID-19 has progressed rapidly over the last 6 months.: How to cite this article: Prayag S ...

    Abstract Coronavirus disease-2019 (COVID-19) pandemic has put a severe strain on the healthcare services around the globe. Among the most affected areas of the hospital is critical care. A large number of patients of COVID-19 need critical care especially respiratory care. The acute hypoxemic respiratory failure (AHRF) due to COVID-19 needs careful understanding and strategies for management. Research in AHRF due to COVID-19 has progressed rapidly over the last 6 months.
    How to cite this article: Prayag S. Respiratory Care for Severe COVID-19. Indian J Crit Care Med 2020;24(7):493-495.
    Keywords covid19
    Language English
    Publishing date 2020-09-18
    Publishing country India
    Document type Editorial
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Respiratory Care for Severe COVID-19

    Prayag, Shirish

    Indian J Crit Care Med

    Abstract: ... to COVID-19 has progressed rapidly over the last 6 months. How to cite this article: Prayag S. Respiratory ...

    Abstract Coronavirus disease-2019 (COVID-19) pandemic has put a severe strain on the healthcare services around the globe. Among the most affected areas of the hospital is critical care. A large number of patients of COVID-19 need critical care especially respiratory care. The acute hypoxemic respiratory failure (AHRF) due to COVID-19 needs careful understanding and strategies for management. Research in AHRF due to COVID-19 has progressed rapidly over the last 6 months. How to cite this article: Prayag S. Respiratory Care for Severe COVID-19. Indian J Crit Care Med 2020;24(7):493-495.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #749207
    Database COVID19

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  4. Article: Enzyme Patterns and Factors Associated with Mortality among Patients with Carbapenem Resistant

    Prayag, Parikshit Shirish / Patwardhan, Sampada A / Joshi, Rasika S / Panchakshari, Shweta P / Rane, Tejashree / Prayag, Amrita P

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 27, Issue 9, Page(s) 663–668

    Abstract: ... associated with mortality (: Conclusion: A. baumannii: How to cite this article: Prayag PS, Patwardhan ... SA, Joshi RS, Panchakshari SP, Rane T, Prayag AP. Enzyme Patterns and Factors Associated ...

    Abstract Introduction: In the Indian setting, antimicrobial resistance in
    Materials and methods: A retrospective analysis of 50 episodes of bacteremia caused by CRAB. We analyzed the enzyme patterns and the susceptibility rates to various antibiotics.
    Results: The resistance rates for amikacin, tigecycline, minocycline, and fluoroquinolones were 88, 82, 50, and 88% respectively. OXA-23 was the most commonly isolated enzyme (86% of the isolates produced OXA-23) followed by OXA-51 and NDM. The overall mortality was high (58%). On univariate analysis, pneumonia, and higher Pitt's bacteremia score were significantly associated with mortality (
    Conclusion: A. baumannii
    How to cite this article: Prayag PS, Patwardhan SA, Joshi RS, Panchakshari SP, Rane T, Prayag AP. Enzyme Patterns and Factors Associated with Mortality among Patients with Carbapenem Resistant
    Language English
    Publishing date 2023-09-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Fecal Microbiota Transplantation for

    Prayag, Parikshit Shirish / Patwardhan, Sampada Ajeet / Ajapuje, Preeti Shankarrao / Melinkeri, Sameer / Gadhikar, Harshal / Palnitkar, Sachin / Simbasivam, Ramya / Joshi, Rasika Saheel / Baheti, Abhijit / Sheth, Urmi Sitanshu / Prayag, Amrita Parikshit

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2024  Volume 28, Issue 2, Page(s) 106–110

    Abstract: ... to cite this article: Prayag PS, Patwardhan SA, Ajapuje PS, Melinkeri S, Gadhikar H, Palnitkar S, ...

    Abstract Objectives: Fecal microbiota transplantation (FMT) is an emerging option for recurrent or refractory
    Methods: A prospective observational study of HSCT recipients with CDAD who received FMT in our center.
    Results: A total of 13 patients were included. All the patients were allogenic HSCT recipients; FMT was performed in seven patients due to refractory CDAD, in five patients due to the presence of both CDAD and graft vs host disease (GVHD), and in 1 patient due to recurrent CDAD. The approach to FMT was colonoscopic in 10 (77%) patients. Only one patient reported bacteremia and one patient had candidemia, both of which were unrelated to FMT. Of the 10 patients who had complete resolution of CDAD, only one patient presented with a recurrence of CDAD within 8 weeks post-FMT.
    Conclusion: This is the first study from India using FMT as a therapeutic modality for CDAD in the setting of HSCT. Here we demonstrate that FMT in India is an effective option, especially when patients have refractory CDAD, recurrent CDAD, or both GVHD and CDAD. Further studies should explore the efficacy and feasibility of FMT in India.
    How to cite this article: Prayag PS, Patwardhan SA, Ajapuje PS, Melinkeri S, Gadhikar H, Palnitkar S,
    Language English
    Publishing date 2024-02-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Therapeutic Drug Monitoring of Isavuconazole: Lessons Learnt from a Real-life Setting in a Tertiary Care Center in India.

    Prayag, Parikshit Shirish / Soman, Rajeev N / Panchakshari, Shweta P / Ajapuje, Preeti S / Mahale, Namita P / Dhupad, Surabhi / Patwardhan, Sampada A / Naik, Sadanand S / Narawade, Sharwari / Athavale, Anand / Saseedharan, Sanjith / Melinkeri, Sameer / Prayag, Amrita P

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 27, Issue 4, Page(s) 260–264

    Abstract: ... How to cite this article: Prayag PS, Soman RN, Panchakshari SP, Ajapuje PS, Mahale NP, Dhupad S, ...

    Abstract Introduction: Isavuconazole is an emerging therapeutic option for invasive infections caused by molds, especially aspergillosis and mucormycosis. Isavuconazole has predictable pharmacokinetics and good bioavailability. These attributes have led to some doubts regarding the need for therapeutic drug monitoring (TDM). There are no data from India regarding TDM for isavuconazole.
    Methods: A retrospective analysis of 50 patients who received oral isavuconazole for therapeutic purposes. Plasma isavuconazole levels were measured using a reversed phase high-performance liquid chromatography (HPLC) and UV detector with acetonitrile (ACN) as protein precipitating solvent.
    Results: Of the 50 cases, 5 (10.0%) patients had subtherapeutic levels, while 45 (90.0%) had therapeutic levels. Higher body weight and solid organ transplantation (SOT) were significantly associated with subtherapeutic levels of isavuconazole (
    Conclusion: Our study reemphasizes the need of TDM for isavuconazole and adds to the growing evidence for the need to obtain drug levels. Factors associated with subtherapeutic levels of isavuconazole need to be assessed in larger studies to help identify those patients who are at risk of having subtherapeutic drug levels.
    How to cite this article: Prayag PS, Soman RN, Panchakshari SP, Ajapuje PS, Mahale NP, Dhupad S,
    Language English
    Publishing date 2023-06-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Let Us Eradicate All Bias, Gender Included

    Kulkarni, Padmaj S / Prayag, Amrita / Borker, Anupama Shirish / Sirohi, Bhawna

    Indian Journal of Medical and Paediatric Oncology

    2020  Volume 41, Issue 01, Page(s) 1–3

    Language English
    Publishing date 2020-01-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2181724-8
    ISSN 0975-2129 ; 0971-5851 ; 0975-2129
    ISSN (online) 0975-2129
    ISSN 0971-5851 ; 0975-2129
    DOI 10.4103/ijmpo.ijmpo_93_20
    Database Thieme publisher's database

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  8. Article: Indian Society of Critical Care Medicine Consensus Statement for Prevention of Venous Thromboembolism in the Critical Care Unit.

    Jagiasi, Bharat G / Chhallani, Akshaykumar A / Dixit, Subhal B / Kumar, Rishi / Pandit, Rahul A / Govil, Deepak / Prayag, Shirish / Zirpe, Kapil G / Mishra, Rajesh C / Chanchalani, Gunjan / Kapadia, Farhad N

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 26, Issue Suppl 2, Page(s) S51–S65

    Abstract: Deep vein thrombosis (DVT) is a preventable complication of critical illness, and this guideline aims to convey a pragmatic approach to the problem. Guidelines have multiplied over the last decade, and their utility has become increasingly conflicted as ... ...

    Abstract Deep vein thrombosis (DVT) is a preventable complication of critical illness, and this guideline aims to convey a pragmatic approach to the problem. Guidelines have multiplied over the last decade, and their utility has become increasingly conflicted as the reader interprets all suggestions or recommendations as something that must be followed. The nuances of grade of recommendation vs level of evidence are often ignored, and the difference between a "we suggest" vs a "we recommend" is overlooked. There is a general unease among clinicians that failure to follow the guidelines translates to poor medical practice and legal culpability. We attempt to overcome these limitations by highlighting ambiguity when it occurs and refraining from dogmatic recommendations in the absence of robust evidence. Readers and practitioners may find the lack of specific recommendations unsatisfactory, but we believe that true ambiguity is better than inaccurate certainty. We have attempted to comply with the guidelines on how to create guidelines.
    How to cite this article: Jagiasi BG, Chhallani AA, Dixit SB, Kumar R, Pandit RA, Govil D,
    Language English
    Publishing date 2023-02-21
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Noninvasive Respiratory Assist Devices in the Management of COVID-19-related Hypoxic Respiratory Failure: Pune ISCCM COVID-19 ARDS Study Consortium (PICASo).

    Jog, Sameer / Zirpe, Kapil / Dixit, Subhal / Godavarthy, Purushotham / Shahane, Manasi / Kadapatti, Kayanoosh / Shah, Jignesh / Borawake, Kapil / Khan, Zafer / Shukla, Urvi / Jahagirdar, Ashwini / Dhat, Venkatesh / D'costa, Pradeep / Shelgaonkar, Jayant / Deshmukh, Abhijit / Khatib, Khalid / Prayag, Shirish

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 26, Issue 7, Page(s) 791–797

    Abstract: Objective: To determine whether high-flow nasal oxygen (HFNO) or noninvasive ventilator (NIV) can avoid invasive mechanical ventilation (IMV) in COVID-19-related acute respiratory distress syndrome (ADRS), and the outcome predictors of these modalities.! ...

    Abstract Objective: To determine whether high-flow nasal oxygen (HFNO) or noninvasive ventilator (NIV) can avoid invasive mechanical ventilation (IMV) in COVID-19-related acute respiratory distress syndrome (ADRS), and the outcome predictors of these modalities.
    Design: Multicenter retrospective study conducted in 12 ICUs in Pune, India.
    Patients: Patients with COVID-19 pneumonia who had PaO
    Intervention: HFNO and/or NIV.
    Measurements: The primary outcome was to assess the need of IMV. Secondary outcomes were death at Day 28 and mortality rates in different treatment groups.
    Main results: Among 1,201 patients who met the inclusion criteria, 35.9% (431/1,201) were treated successfully with HFNO and/or NIV and did not require IMV. About 59.5% (714/1,201) patients needed IMV for the failure of HFNO and/or NIV. About 48.3, 61.6, and 63.6% of patients who were treated with HFNO, NIV, or both, respectively, needed IMV. The need of IMV was significantly lower in the HFNO group (
    Conclusions: During COVID-19 pandemic surge, HFNO and/or NIV could successfully avoid IMV in 35.5% individuals with PO
    How to cite this article: Jog S, Zirpe K, Dixit S, Godavarthy P, Shahane M, Kadapatti K,
    Language English
    Publishing date 2023-02-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: ICUs worldwide: critical care in India.

    Prayag, Shirish

    Critical care (London, England)

    2002  Volume 6, Issue 6, Page(s) 479–480

    MeSH term(s) Humans ; India ; Intensive Care Units/organization & administration
    Language English
    Publishing date 2002-08-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041406-7
    ISSN 1364-8535
    ISSN 1364-8535
    DOI 10.1186/cc1544
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