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  1. Article: Preface from European Respiratory Society President 2018 Mina Gaga and European Respiratory Society Early-Career Member Committee Chair Lieuwe D. J. Bos.

    Gaga, Mina / Bos, Lieuwe D J

    Journal of thoracic disease

    2018  Volume 10, Issue Suppl 25, Page(s) S2975–S2976

    Language English
    Publishing date 2018-10-05
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.08.119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to Volpicelli and Bouhemad.

    Smit, Marry R / Bos, Lieuwe D J

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 1, Page(s) 113–114

    MeSH term(s) Humans ; Lung ; Respiratory Distress Syndrome
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202304-0683LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Targeted immunomodulation: a primer for intensivists.

    Janssen, Malou / Endeman, Henrik / Bos, Lieuwe D J

    Intensive care medicine

    2023  Volume 49, Issue 4, Page(s) 462–464

    MeSH term(s) Humans ; Critical Care ; Intensive Care Units
    Language English
    Publishing date 2023-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-023-07009-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1089: Show issues Location:
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  4. Article ; Online: The Emulated Targeted Trial: A Causal, But Never Casual, Surrogate for Randomized Clinical Trials.

    Wendel-Garcia, Pedro D / Bos, Lieuwe D J

    Chest

    2023  Volume 164, Issue 4, Page(s) 816–817

    MeSH term(s) Humans ; Randomized Controlled Trials as Topic ; Causality ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Molecular diagnostics in severe pneumonia: a new dawn or false promise?

    Conway Morris, Andrew / Bos, Lieuwe D J / Nseir, Saad

    Intensive care medicine

    2022  Volume 48, Issue 6, Page(s) 740–742

    MeSH term(s) Humans ; Pathology, Molecular ; Pneumonia/diagnosis
    Language English
    Publishing date 2022-05-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06722-0
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  6. Article: The ESICM datathon and the ESICM and ICMx data science strategy.

    Elbers, Paul / Thoral, Patrick / Bos, Lieuwe D J / Greco, Massimiliano / Wendel-Garcia, Pedro D / Ercole, Ari

    Intensive care medicine experimental

    2024  Volume 12, Issue 1, Page(s) 29

    Language English
    Publishing date 2024-03-12
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2740385-3
    ISSN 2197-425X
    ISSN 2197-425X
    DOI 10.1186/s40635-024-00615-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19-related Acute Respiratory Distress Syndrome: Not So Atypical.

    Bos, Lieuwe D J

    American journal of respiratory and critical care medicine

    2020  Volume 202, Issue 4, Page(s) 622–624

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Diagnosis, Differential ; Disease Management ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Respiratory Distress Syndrome/diagnosis ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-24
    Publishing country United States
    Document type Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202004-1423LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Gut-lung crosstalk during critical illness.

    Nath, Sridesh / Kitsios, Georgios D / Bos, Lieuwe D J

    Current opinion in critical care

    2023  Volume 29, Issue 2, Page(s) 130–137

    Abstract: Purpose of review: Study of organ crosstalk in critical illness has uncovered complex biological communication between different organ systems, but the role of microbiota in organ crosstalk has received limited attention. We highlight the emerging ... ...

    Abstract Purpose of review: Study of organ crosstalk in critical illness has uncovered complex biological communication between different organ systems, but the role of microbiota in organ crosstalk has received limited attention. We highlight the emerging understanding of the gut-lung axis, and how the largest biomass of the human body in the gut may affect lung physiology in critical illness.
    Recent findings: Disruption of healthy gut microbial communities and replacement by disease-promoting pathogens (pathobiome) generates a maladaptive transmitter of messages from the gut to the lungs, connected via the portal venous and the mesenteric lymphatic systems. Gut barrier impairment allows for microbial translocation (living organisms or cellular fragments) to the lungs. Host-microbiota interactions in the gut mucosa can also impact lung physiology through microbial metabolite secretion or host-derived messengers (hormones, cytokines or immune cells). Clinical examples like the prevention of ventilator-associated pneumonia by selective decontamination of the digestive tract show that the gut-lung axis can be manipulated therapeutically.
    Summary: A growing body of evidence supports the pathophysiological relevance of the gut-lung axis, yet we are only at the brink of understanding the therapeutic and prognostic relevance of the gut microbiome, metabolites and host-microbe interactions in critical illness.
    MeSH term(s) Humans ; Critical Illness ; Gastrointestinal Microbiome ; Microbiota ; Lung ; Cytokines
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000001015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: COVID-19 Pathophysiology: An Opportunity to Start Appreciating Time-Dependent Variation.

    van Vught, Lonneke A / Bos, Lieuwe D J

    American journal of respiratory and critical care medicine

    2022  Volume 205, Issue 5, Page(s) 483–485

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202112-2857ED
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  10. Article ; Online: Slicing and dicing ARDS: we almost forgot the lungs.

    Smit, Marry R / Bos, Lieuwe D J

    Critical care (London, England)

    2021  Volume 25, Issue 1, Page(s) 180

    Language English
    Publishing date 2021-05-28
    Publishing country England
    Document type Editorial
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-021-03611-8
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